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From Bioblast
Year | Reference | Coupling | Pathway | Preparation | Organism | Tissue;cell | |
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Garcia-Roche 2022 J Dairy Sci | 2022 | García-Roche M, Talmón D, Cañibe G, Astessiano AL, Mendoza A, Quijano C, Cassina A, Carriquiry M (2022) Differential hepatic mitochondrial function and gluconeogenic gene expression in 2 Holstein strains in a pasture-based system. https://doi.org/10.3168/jds.2021-21358 | LEAK OXPHOS ET | N S NS ROX | Intact cells | Bovines | Liver |
Gonzalez-Franquesa 2022 Redox Biol | 2022 | Gonzalez-Franquesa A, Gama-Perez P, Kulis M, Szczepanowska K, Dahdah N, Moreno-Gomez S, Latorre-Pellicer A, Fernández-Ruiz R, Aguilar-Mogas A, Hoffman A, Monelli E, Samino S, Miró-Blanch J, Oemer G, Duran X, Sanchez-Rebordelo E, Schneeberger M, Obach M, Montane J, Castellano G, Chapaprieta V, Sun W, Navarro L, Prieto I, Castaño C, Novials A, Gomis R, Monsalve M, Claret M, Graupera M, Soria G, Wolfrum C, Vendrell J, Fernández-Veledo S, Enríquez JA, Carracedo A, Perales JC, Nogueiras R, Herrero L, Trifunovic A, Keller MA, Yanes O, Sales-Pardo M, Guimerà R, Blüher M, Martín-Subero JI, Garcia-Roves PM (2022) Remission of obesity and insulin resistance is not sufficient to restore mitochondrial homeostasis in visceral adipose tissue. https://doi.org/10.1016/j.redox.2022.102353 | LEAK OXPHOS ET | N S NS ROX | Permeabilized tissue Homogenate | Mouse | Skeletal muscle Nervous system Liver Fat |
Takada 2022 Proc Natl Acad Sci U S A | 2022 | Takada S, Maekawa S, Furihata T, Kakutani N, Setoyama D, Ueda K, Nambu H, Hagiwara H, Handa H, Fumoto Y, Hata S, Masunaga T, Fukushima A, Yokota T, Kang D, Kinugawa S, Sabe H (2022) Succinyl-CoA-based energy metabolism dysfunction in chronic heart failure. Proc Natl Acad Sci U S A 119: e2203628119. | LEAK OXPHOS | Isolated mitochondria | Mouse | Heart | |
Hadanny 2022 Sports Med Open | 2022 | Hadanny A, Hachmo Y, Rozali D, Catalogna M, Yaakobi E, Sova M, Gattegno H, Abu Hamed R, Lang E, Polak N, Friedman M, Finci S, Zemel Y, Bechor Y, Gal N, Efrati S (2022) Effects of hyperbaric oxygen therapy on mitochondrial respiration and physical performance in middle-aged athletes: a blinded, randomized controlled trial. | LEAK OXPHOS ET | N S NS ROX | Permeabilized tissue | Human | Skeletal muscle |
Lai 2022 PLoS One | 2022 | Lai RE, Holman ME, Chen Q, Rivers J, Lesnefsky EJ, Gorgey AS (2022) Assessment of mitochondrial respiratory capacity using minimally invasive and noninvasive techniques in persons with spinal cord injury. PLoS One 17:e0265141. | LEAK OXPHOS | N S | Permeabilized tissue | Skeletal muscle | |
Quemeneur 2022 Sci Rep | 2022 | Quéméneur JB, Danion M, Cabon J, Collet S, Zambonino-Infante JL, Salin K (2022) The relationships between growth rate and mitochondrial metabolism varies over time. https://doi.org/10.1038/s41598-022-20428-9 | LEAK OXPHOS | N CIV NS ROX | Homogenate | Fishes | Skeletal muscle |
Chojnacka 2022 Mol Biol Cell | 2022 | Chojnacka KJ, Elancheliyan P, Mussulini BHM, Mohanraj K, Callegari S, Gosk A, Banach T, Góral T, Szczepanowska K, Rehling P, Serwa RA, Chacinska A (2022) Ovarian carcinoma immunoreactive antigen-like protein 2 (OCIAD2) is a novel complex III-specific assembly factor in mitochondria. https://doi.org/10.1091/mbc.e21-03-0143 | LEAK ROUTINE OXPHOS ET | F N S Gp CIV NS ROX | Permeabilized cells Intact cells | Human | HEK |
Serna 2022 BEC | 2022 | Serna JDC, Ramos VM, Cabral-Costa JV, Vilas-Boas EA, Amaral AG, Ohya G, da Silva CCC, Kowaltowski AJ (2022) Measuring mitochondrial Ca2+ efflux in isolated mitochondria and permeabilized cells. Bioenerg Commun 2022.7. https://doi.org/10.26124/bec:2022-0007 | LEAK OXPHOS | S ROX | Permeabilized cells Isolated mitochondria | Human Mouse | Liver Other cell lines |
Pedersen 2022 Nat Commun | 2022 | Pedersen JS, Rygg MO, Chrøis K, Sustarsic EG, Gerhart-Hines Z, Wever Albrechtsen NJ, Serizawa RR, Kristiansen VB, Basse AL, Boilesen AEB, Olsen BH, Hansen T, Gluud LL, Madsbad S, Larsen S, Bendtsen F, Dela F (2022) Influence of NAFLD and bariatric surgery on hepatic and adipose tissue mitochondrial biogenesis and respiration. https://doi.org/10.1038/s41467-022-30629-5 | LEAK OXPHOS ET | F N S CIV NS | Permeabilized tissue | Human | Liver Fat |
Trewin 2022 BMC Biol | 2022 | Trewin AJ, Silver J, Dillon HT, Della Gatta PA, Parker L, Hiam DS, Lee YP, Richardson M, Wadley GD, Lamon S (2022) Long non-coding RNA Tug1 modulates mitochondrial and myogenic responses to exercise in skeletal muscle. https://doi.org/10.1186/s12915-022-01366-4 | LEAK OXPHOS ET | N S NS ROX | Permeabilized cells | Mouse | Skeletal muscle |
Soares 2022 Geroscience | 2022 | Soares RN, Ramirez-Perez FI, Cabral-Amador FJ, Morales-Quinones M, Foote CA, Ghiarone T, Sharma N, Power G, Smith JA, Rector RS, Martinez-Lemus LA, Padilla J, Manrique-Acevedo C (2022) SGLT2 inhibition attenuates arterial dysfunction and decreases vascular F-actin content and expression of proteins associated with oxidative stress in aged mice. https://doi.org/10.1007/s11357-022-00563-x | LEAK OXPHOS ET | N S NS ROX | Permeabilized cells | Mouse | Endothelial;epithelial;mesothelial cell |
Loughland 2022 J Exp Biol | 2022 | Loughland I, Lau GY, Jolly J, Seebacher F (2022) Rates of warming impact oxidative stress in zebrafish (Danio rerio). | LEAK OXPHOS ET | N NS | Isolated mitochondria | Zebrafish | Skeletal muscle |
Spielmann 2022 Mamm Genome | 2022 | Spielmann N, Schenkl C, Komlódi T, da Silva-Buttkus P, Heyne E, Rohde J, Amarie OV, Rathkolb B, Gnaiger E, Doenst T, Fuchs H, Gailus-Durner V, de Angelis MH, Szibor M (2022) Knockout of the Complex III subunit Uqcrh causes bioenergetic impairment and cardiac contractile dysfunction. Mamm Genome 10.1007/s00335-022-09973-w | LEAK OXPHOS ET | N S NS ROX | Intact organism Isolated mitochondria | Mouse | Heart |
Cho 2022 BMC Med | 2022 | Cho J, Johnson BD, Watt KD, Niven AS, Yeo D, Kim CH (2022) Exercise training attenuates pulmonary inflammation and mitochondrial dysfunction in a mouse model of high-fat high-carbohydrate-induced NAFLD. https://doi.org/10.1186/s12916-022-02629-1 | LEAK OXPHOS | N NS | Homogenate | Mouse | Lung;gill |
Damgaard 2022 iScience | 2022 | Damgaard MV, Nielsen TS, Basse AL, Chubanava S, Trost K, Moritz T, Dellinger RW, Larsen S, Treebak JT (2022) Intravenous nicotinamide riboside elevates mouse skeletal muscle NAD+ without impacting respiratory capacity or insulin sensitivity. https://doi.org/10.1016/j.isci.2022.103863 | LEAK OXPHOS | N NS ROX | Permeabilized tissue | Mouse | Skeletal muscle |
Lehto 2022 Neurochem Res | 2022 | Lehto A, Koch K, Barnstorf-Brandes J, Viel C, Fuchs M, Klein J (2022) ß-Hydroxybutyrate improves mitochondrial function after transient ischemia in the mouse. https://doi.org/10.1007/s11064-022-03637-6 | LEAK OXPHOS ET | N S CIV NS ROX | Isolated mitochondria | Mouse | Nervous system |
Jayasankar 2022 ACS Omega | 2022 | Jayasankar V, Vrdoljak N, Roma A, Ahmed N, Tcheng M, Minden MD, Spagnuolo PA (2022) Novel mango ginger bioactive (2,4,6-trihydroxy-3,5-diprenyldihydrochalcone) inhibits mitochondrial metabolism in combination with Avocatin B. ACS Omega 7:1682-93. https://doi.org/10.1021/acsomega.1c04053 | OXPHOS | F N | Permeabilized cells | ||
Dias 2022 Free Radic Biol Med | 2022 | Dias C, Lourenço CF, Laranjinha J, Ledo A (2022) Modulation of oxidative neurometabolism in ischemia/reperfusion by nitrite. https://doi.org/10.1016/j.freeradbiomed.2022.11.021 | ROUTINE OXPHOS ET | N S ROX | Permeabilized tissue Intact cells | Rat | Nervous system |
Daradics 2022 PLoS One | 2022 | Daradics N, Horvath G, Tretter L, Paal A, Fulop A, Budai A, Szijarto A (2022) The effect of Cyclophilin D depletion on liver regeneration following associating liver partition and portal vein ligation for staged hepatectomy. https://doi.org/10.1371/journal.pone.0271606 | LEAK OXPHOS | N S | Isolated mitochondria | Mouse | Liver |
Cossin-Sevrin 2022 J Exp Biol | 2022 | Cossin-Sevrin N, Hsu BY, Marciau C, Viblanc VA, Ruuskanen S, Stier A (2022) Effect of prenatal glucocorticoids and thyroid hormones on developmental plasticity of mitochondrial aerobic metabolism, growth and survival: an experimental test in wild great tits. https://doi.org/10.1242/jeb.243414 | LEAK OXPHOS | N NS | Intact cells | Birds | Blood cells |
Paulus 2022 Basic Res Cardiol | 2022 | Paulus MG, Renner K, Nickel AG, Brochhausen C, Limm K, Zügner E, Baier MJ, Pabel S, Wallner S, Birner C, Luchner A, Magnes C, Oefner PJ, Stark KJ, Wagner S, Maack C, Maier LS, Streckfuss-Bömeke K, Sossalla S, Dietl A (2022) Tachycardiomyopathy entails a dysfunctional pattern of interrelated mitochondrial functions. https://doi.org/10.1007/s00395-022-00949-0 | OXPHOS ET | NS F ROX | Permeabilized tissue Isolated mitochondria | Rabbit | Heart |
Felix 2022 Chemosphere | 2022 | Félix L, Carreira P, Peixoto F (2022) Effects of chronic exposure of naturally weathered microplastics on oxidative stress level, behaviour, and mitochondrial function of adult zebrafish (Danio rerio). https://doi.org/10.1016/j.chemosphere.2022.136895 | LEAK OXPHOS | N S CIV ROX | Homogenate | Zebrafish | Nervous system Liver |
Rome 2022 Mol Metab | 2022 | Rome FI, Hughey CC (2022) Disrupted liver oxidative metabolism in glycine N-methyltransferase-deficient mice is mitigated by dietary methionine restriction. https://doi.org/10.1016/j.molmet.2022.101452 | LEAK OXPHOS ET | N CIV ROX | Isolated mitochondria | Mouse | Liver |
Yamauchi 2022 Sci Rep | 2022 | Yamauchi Y, Nakamura A, Yokota T, Takahashi K, Kawata S, Tsuchida K, Omori K, Nomoto H, Kameda H, Cho KY, Anzai T, Tanaka S, Terauchi Y, Miyoshi H, Atsumi T (2022) Luseogliflozin preserves the pancreatic beta-cell mass and function in db/db mice by improving mitochondrial function. Sci Rep 12: 9740. | LEAK OXPHOS | Mouse | Islet cell;pancreas;thymus | ||
Vanweert 2022 Nat Commun | 2022 | Vanweert F, Neinast M, Tapia EE, van de Weijer T, Hoeks J, Schrauwen-Hinderling VB, Blair MC, Bornstein MR, Hesselink MKC, Schrauwen P, Arany Z, Phielix E (2022) A randomized placebo-controlled clinical trial for pharmacological activation of BCAA catabolism in patients with type 2 diabetes. https://doi.org/10.1038/s41467-022-31249-9 | LEAK OXPHOS ET | F N NS | Permeabilized tissue | Human | Skeletal muscle |
Wang 2022 Transl Cancer Res | 2022 | Wang B, Liu B, Luo Q, Sun D, Li H, Zhang J, Jin X, Cheng X, Niu J, Yuan Q, Chen Y (2022) PANK1 associates with cancer metabolism and immune infiltration in clear cell renal cell carcinoma: a retrospective prognostic study based on the TCGA database. https://doi.org/10.21037/tcr-22-1488 | LEAK OXPHOS ET | N NS S | Human | Kidney Endothelial;epithelial;mesothelial cell | |
Weiss 2022 J Cell Mol Med | 2022 | Weiss SL, Zhang D, Farooqi S, Wallace DC (2022) Sodium butyrate reverses lipopolysaccharide-induced mitochondrial dysfunction in lymphoblasts. https://doi.org/10.1111/jcmm.17342 | ROUTINE OXPHOS ET | N | Intact cells | Other cell lines | |
McKenna 2022 J Appl Physiol (1985) | 2022 | McKenna CF, Salvador AF, Keeble AR, Khan NA, De Lisio M, Konopka AR, Paluska SA, Burd NA (2022) Muscle strength after resistance training correlates to mediators of muscle mass and mitochondrial respiration in middle-aged adults. https://doi.org/10.1152/japplphysiol.00186.2022 | LEAK OXPHOS ET | NS | Permeabilized tissue | Human | Skeletal muscle |
Siewiera 2022 Int J Mol Sci | 2022 | Siewiera K, Labieniec-Watala M, Kassassir H, Wolska N, Polak D, Watala C (2022) Potential role of mitochondria as modulators of blood platelet activation and reactivity in diabetes and effect of metformin on blood platelet bioenergetics and platelet activation. https://doi.org/10.3390/ijms23073666 | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Intact cells | Rat | Platelet |
Dunn 2021 Arterioscler Thromb Vasc Biol | 2021 | Dunn LL, Kong SMY, Tumanov S, Chen W, Cantley J, Ayer A, Maghzal GJ, Midwinter RG, Chan KH, Ng MKC, Stocker R (2021) Hmox1 (heme oxygenase-1) protects against ischemia-mediated injury via stabilization of HIF-1α (hypoxia-inducible factor-1α). Arterioscler Thromb Vasc Biol 41:317-30. | LEAK OXPHOS ET | F N S NS ROX | Permeabilized tissue | Mouse | Skeletal muscle |
Bischof 2021 Sci Transl Med | 2021 | Bischof C, Mirtschink P, Yuan T, Wu M, Zhu C, Kaur J, Pham MD, Gonzalez-Gonoggia S, Hammer M, Rogg EM, Sharma R, Bottermann K, Gercken B, Hagag E, Berthonneche C, Sossalla S, Stehr SN, Maxeiner J, Duda MA, Latreille M, Zamboni N, Martelli F, Pedrazzini T, Dimmeler S, Krishnan J (2021) Mitochondrial-cell cycle cross-talk drives endoreplication in heart disease. Sci Transl Med 13:eabi7964. | LEAK OXPHOS ET | S | |||
Dos Santos Escaliante 2021 Int J Biol Macromol | 2021 | Dos Santos Escaliante LA, Busato B, de Oliveira Petkowicz CL, Suter Correia Cadena SM, Rodrigues Noleto G (2021) Cytotoxic effect of xyloglucan and oxovanadium (IV/V) xyloglucan complex in HepG2 cells. Int J Biol Macromol 185:40-48. | LEAK OXPHOS | N S CIV ROX | Permeabilized cells | Human | Liver |
Correia 2021 Hum Mutat | 2021 | Correia SP, Moedas MF, Naess K, Bruhn H, Maffezzini C, Calvo-Garrido J, Lesko N, Wibom R, Schober FA, Jemt A, Stranneheim H, Freyer C, Wedell A, Wredenberg A (2021) Severe congenital lactic acidosis and hypertrophic cardiomyopathy caused by an intronic variant in NDUFB7. Hum Mutat 42:378-84. | LEAK OXPHOS | N S NS | Permeabilized cells | Human | Fibroblast |
Hansen 2021 Physiol Rep | 2021 | Hansen C, Olsen K, Pilegaard H, Bangsbo J, Gliemann L, Hellsten Y (2021) High metabolic substrate load induces mitochondrial dysfunction in rat skeletal muscle microvascular endothelial cells. Physiol Rep 9:e14855. | LEAK OXPHOS ET | N S NS ROX | Permeabilized cells Intact cells | Rat | Skeletal muscle Endothelial;epithelial;mesothelial cell |
Zunica 2021 Cancer Metab | 2021 | Zunica ERM, Axelrod CL, Cho E, Spielmann G, Davuluri G, Alexopoulos SJ, Beretta M, Hoehn KL, Dantas WS, Stadler K, King WT, Pergola K, Irving BA, Langohr IM, Yang S, Hoppel CL, Gilmore LA, Kirwan JP (2021) Breast cancer growth and proliferation is suppressed by the mitochondrial targeted furazano[3,4-b]pyrazine BAM15. Cancer Metab 9:36. | LEAK OXPHOS ET | N S CIV NS ROX F DQ | Permeabilized cells Homogenate | Human Mouse | Endothelial;epithelial;mesothelial cell |
Chambers 2021 JCI Insight | 2021 | Chambers KT, Cooper MA, Swearingen AR, Brookheart RT, Schweitzer GG, Weinheimer CJ, Kovacs A, Koves TR, Muoio DM, McCommis KS, Finck BN (2021) Myocardial Lipin 1 knockout in mice approximates cardiac effects of human LPIN1 mutations. JCI Insight 6:134340. | LEAK OXPHOS ET | F N S | Permeabilized tissue | Mouse | Heart |
Szczerbinski 2021 Cells | 2021 | Szczerbinski L, Taylor MA, Puchta U, Konopka P, Paszko A, Citko A, Szczerbinski K, Goscik J, Gorska M, Larsen S, Kretowski A (2021) The response of mitochondrial respiration and quantity in skeletal muscle and adipose tissue to exercise in humans with prediabetes. Cells 10:3013. | LEAK OXPHOS ET | N S | Permeabilized tissue | Human | Skeletal muscle Fat |
Acin-Perez 2021 Life (Basel) | 2021 | Acin-Perez R, Benincá C, Shabane B, Shirihai OS, Stiles L (2021) Utilization of human samples for assessment of mitochondrial bioenergetics: gold standards, limitations, and future perspectives. Life (Basel) 11:949. doi: 10.3390/life11090949 | LEAK ROUTINE OXPHOS ET | Intact organ Permeabilized cells Permeabilized tissue Intact cells | Human | Skeletal muscle Blood cells Fibroblast Platelet | |
Cardoso 2021 BEC MgG | 2021 | Cardoso LHD, Doerrier C, Gnaiger E (2021) Magnesium Green for fluorometric measurement of ATP production does not interfere with mitochondrial respiration. Bioenerg Commun 2021.1. https://doi.org/10.26124/bec:2021-0001 | LEAK OXPHOS ET | N S ROX | Isolated mitochondria | Mouse | Heart |
Mendham 2021 Diabetologia | 2021 | Mendham AE, Goedecke JH, Zeng Y, Larsen S, George C, Hauksson J, Fortuin-de Smidt MC, Chibalin AV, Olsson T, Chorell E (2021) Exercise training improves mitochondrial respiration and is associated with an altered intramuscular phospholipid signature in women with obesity. Diabetologia 64:1642-59. | LEAK OXPHOS ET | F N S NS ROX | Intact cells | Human | Skeletal muscle |
Hoppel 2021 Cells | 2021 | Hoppel F, Garcia-Souza LF, Kantner-Rumplmair W, Burtscher M, Gnaiger E, Pesta D, Calabria E (2021) Human platelet mitochondrial function reflects systemic mitochondrial alterations: a protocol for application in field studies. https://doi.org/10.3390/cells10082088 | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Intact cells | Human | Platelet |
Van Polanen 2021 Physiol Rep | 2021 | van Polanen N, Zacharewicz E, de Ligt M, Timmers S, Moonen-Kornips E, Schaart G, Hoeks J, Schrauwen P, Hesselink MKC (2021) Resveratrol-induced remodelling of myocellular lipid stores: A study in metabolically compromised humans. Physiol Rep 9:e14692. | OXPHOS ET | F N | Permeabilized tissue | Human | Skeletal muscle |
Viel 2021 Pharmaceuticals (Basel) | 2021 | Viel C, Brandtner AT, Weißhaar A, Lehto A, Fuchs M, Klein J (2021) Effects of magnesium orotate, benfotiamine and a combination of vitamins on mitochondrial and cholinergic function in the TgF344-AD rat model of Alzheimer's disease. https://doi.org/10.3390/ph14121218 | LEAK OXPHOS ET | N S CIV ROX | Isolated mitochondria | Rat | Nervous system |
Morgan 2021 Resuscitation | 2021 | Morgan RW, Sutton RM, Himebauch AS, Roberts AL, Landis WP, Lin Y, Starr J, Ranganathan A, Delso N, Mavroudis CD, Volk L, Slovis J, Marquez AM, Nadkarni VM, Hefti M, Berg RA, Kilbaugh TJ (2021) A randomized and blinded trial of inhaled nitric oxide in a piglet model of pediatric cardiopulmonary resuscitation. Resuscitation 162:274-83 . | LEAK OXPHOS | N NS | Homogenate | Pig | Nervous system |
Gvozdjakova 2021 PLoS One | 2021 | Gvozdjáková A, Sumbalová Z, Kucharská J, Szamosová M, Čápová L, Rausová Z, Vančová O, Mojto V, Langsjoen P, Palacka P (2021) Platelet mitochondrial respiration and coenzyme Q10 could be used as new diagnostic strategy for mitochondrial dysfunction in rheumatoid diseases. PLoS ONE 16:e0256135. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Intact cells | Human | Platelet |
Moon 2021 J Lipid Res | 2021 | Moon SH, Dilthey BG, Liu X, Guan S, Sims HF, Gross RW (2021) High-Fat diet activates liver iPLA2γ generating eicosanoids that mediate metabolic stress. J Lipid Res 62:100052. | LEAK OXPHOS ET | N S NS | Isolated mitochondria | Mouse | Liver |
Flensted-Jensen 2021 Free Radic Biol Med | 2021 | Flensted-Jensen M, Gram M, Dela F, Helge JW, Larsen S (2021) Six weeks of high intensity cycle training reduces H2O2 emission and increases antioxidant protein levels in obese adults with risk factors for type 2 diabetes. Free Radic Biol Med 173:1-6. | LEAK OXPHOS | N NS | Permeabilized tissue | Human | Skeletal muscle |
Sahl 2021 Adipocyte | 2021 | Sahl RE, Høy Helms EF, Schmücker M, Flensted-Jensen M, Ingersen A, Morville T, Dela F, Helge JW, Larsen S (2021) Reliability and variation in mitochondrial respiration in human adipose tissue. Adipocyte 10:605-11. | LEAK OXPHOS ET | N NS | Permeabilized cells | Human | Fat |
Goldberg 2021 Biochem J | 2021 | Goldberg EJ, Buddo KA, McLaughlin KL, Fernandez RF, Pereyra AS, Psaltis CE, Lin CT, Hagen JT, Boykov IN, Nguyen TK, Gowdy KM, Ellis JM, Neufer PD, McClung JM, Fisher-Wellman KH (2021) Tissue-specific characterization of mitochondrial branched-chain keto acid oxidation using a multiplexed assay platform. Biochem J 476:1521-37. | LEAK OXPHOS ET | N S NS ROX F | Isolated mitochondria | Mouse | Heart Skeletal muscle Liver |
MacCannell 2021 Int J Obes (Lond) | 2021 | MacCannell ADV, Futers TS, Whitehead A, Moran A, Witte KK, Roberts LD (2021) Sexual dimorphism in adipose tissue mitochondrial function and metabolic flexibility in obesity. Int J Obes (Lond) 45:1773-81. | LEAK OXPHOS ET | N S NS ROX | Permeabilized tissue | Mouse | Fat |
Riguet 2021 Nat Commun | 2021 | Riguet N, Mahul-Mellier AL, Maharjan N, Burtscher J, Croisier M, Knott G, Hastings J, Patin A, Reiterer V, Farhan H, Nasarov S, Lashuel HA (2021) Nuclear and cytoplasmic huntingtin inclusions exhibit distinct biochemical composition, interactome and ultrastructural properties. Nat Commun 12:6579. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Intact cells | Human | HEK |
Deline 2021 Biochim Biophys Acta Bioenerg | 2021 | Deline ML, Grashei M, van Heijster FHA, Schilling F, Straub J, Fromme T (2021) Adenylate kinase derived ATP shapes respiration and calcium storage of isolated mitochondria. Biochim Biophys Acta Bioenerg 1862:148409. | OXPHOS LEAK | S | Isolated mitochondria | Mouse | Liver |
Colin 2021 J Cell Mol Med | 2021 | Colin M, Dechene L, Ceusters J, Niesten A, Demazy C, Lagneaux L, Zouaoui Boudjeltia K, Franck T, Van Antwerpen P, Renard P, Mathieu V, Serteyn D (2021) Priming of mesenchymal stem cells with a hydrosoluble form of curcumin allows keeping their mesenchymal properties for cell-based therapy development. J Cell Mol Med 25:4877-81. | LEAK OXPHOS ET | N S NS | Intact cells | Horse | Stem cells |
Dubinin 2021 Free Radic Biol Med | 2021 | Dubinin MV, Semenova AA, Ilzorkina AI, Penkov NV, Nedopekina DA, Sharapov VA, Khoroshavina EI, Davletshin EV, Belosludtseva NV, Spivak AY, Belosludtsev KN (2021) Mitochondria-targeted prooxidant effects of betulinic acid conjugated with delocalized lipophilic cation F16. Free Radic Biol Med 168:55-69. | LEAK OXPHOS ET | N S NS | Isolated mitochondria | Rat | Liver |
Elksnis 2021 Clin Sci (Lond) | 2021 | Elksnis A, Schiffer TA, Palm F, Wang Y, Cen J, Turpaev K, Ngamjariyawat A, Younis S, Huang S, Shen Y, Leng Y, Bergsten P, Karlsborn T, Welsh N, Wang X (2021) Imatinib protects against human beta-cell death via inhibition of mitochondrial respiration and activation of AMPK. Clin Sci (Lond) 135:2243-63. | OXPHOS ET | N S | Isolated mitochondria | Rat | Kidney |
Gratl 2021 J Transl Med | 2021 | Gratl A, Pesta D, Gruber L, Speichinger F, Raude B, Omran S, Greiner A, Frese JP (2021) The effect of revascularization on recovery of mitochondrial respiration in peripheral artery disease: a case control study. https://doi.org/10.1186/s12967-021-02908-0J | LEAK OXPHOS ET | F N NS | Permeabilized tissue | Human | Skeletal muscle |
Thoral 2021 Biol Lett | 2021 | Thoral E, Roussel D, Chinopoulos C, Teulier L, Salin K (2021) Low oxygen levels can help to prevent the detrimental effect of acute warming on mitochondrial efficiency in fish. Biol Lett 17:20200759. | LEAK OXPHOS | N CIV NS ROX | Homogenate | Fishes | Skeletal muscle |
Sighel 2021 Cell Rep | 2021 | Sighel D, Notarangelo M, Aibara S, Re A, Ricci G, Guida M, Soldano A, Adami V, Ambrosini C, Broso F, Rosatti EF, Longhi S, Buccarelli M, D'Alessandris QG, Giannetti S, Pacioni S, Ricci-Vitiani L, Rorbach J, Pallini R, Roulland S, Amunts A, Mancini I, Modelska A, Quattrone A (2021) Inhibition of mitochondrial translation suppresses glioblastoma stem cell growth. Cell Rep 35:109024. | ROUTINE OXPHOS | N S NS ROX | Permeabilized cells Intact cells | Human | Nervous system Stem cells |
Hoene 2021 Mol Metab | 2021 | Hoene M, Kappler L, Kollipara L, Hu C, Irmler M, Bleher D, Hoffmann C, Beckers J, Hrabě de Angelis M, Häring HU, Birkenfeld AL, Peter A, Sickmann A, Xu G, Lehmann R, Weigert C (2021) Exercise prevents fatty liver by modifying the compensatory response of mitochondrial metabolism to excess substrate availability. Mol Metab 54:101359. | LEAK OXPHOS ET | F N S NS ROX | Isolated mitochondria | Mouse | Liver |
Baldini 2021 Life Sci | 2021 | Baldini F, Fabbri R, Eberhagen C, Voci A, Portincasa P, Zischka H, Vergani L (2021) Adipocyte hypertrophy parallels alterations of mitochondrial status in a cell model for adipose tissue dysfunction in obesity. Life Sci 265:118812. | LEAK OXPHOS ET | N S NS ROX | Permeabilized cells | Mouse | Fibroblast |
Su 2021 Chin J Physiol | 2021 | Su Y, Wang Y, Xu P, Sun Y, Ping Z, Huang H, Cao X (2021) Study on the time-effectiveness of exercise preconditioning on heart protection in exhausted rats. Chin J Physiol 64:97-105. | LEAK OXPHOS | N S CIV NS ROX | Permeabilized tissue | Rat | Heart |
Sharma 2021 Cancer Cell Int | 2021 | Sharma P, Sharma V, Ahluwalia TS, Dogra N, Kumar S, Singh S (2021) Let-7a induces metabolic reprogramming in breast cancer cells via targeting mitochondrial encoded ND4. Cancer Cell Int 21:629. | LEAK OXPHOS | N S | Permeabilized cells | Human | Endothelial;epithelial;mesothelial cell |
Elliehausen 2021 Exp Gerontol | 2021 | Elliehausen CJ, Minton DM, Nichol AD, Konopka AR (2021) Skeletal muscle mitochondrial respiration in a model of age-related osteoarthritis is impaired after dietary rapamycin. https://doi.org/10.1016/j.exger.2021.111579 | LEAK OXPHOS ET | N S NS ROX | Permeabilized tissue | Guinea pig | Skeletal muscle |
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Valera-Alberni 2021 Cell Rep | 2021 | Valera-Alberni M, Joffraud M, Miro-Blanch J, Capellades J, Junza A, Dayon L, Núñez Galindo A, Sanchez-Garcia JL, Valsesia A, Cercillieux A, Söllner F, Ladurner AG, Yanes O, Cantó C (2021) Crosstalk between Drp1 phosphorylation sites during mitochondrial remodeling and their impact on metabolic adaptation. Cell Rep 36:109565. | LEAK OXPHOS ET | N S NS ROX | Homogenate Isolated mitochondria | Mouse | Liver Fat |
Jacome-Sosa 2021 Commun Biol | 2021 | Jacome-Sosa M, Miao ZF, Peche VS, Morris EF, Narendran R, Pietka KM, Samovski D, Lo HG, Pietka T, Varro A, Love-Gregory L, Goldenring JR, Kuda O, Gamazon ER, Mills JC, Abumrad NA (2021) CD36 maintains the gastric mucosa and associates with gastric disease. Commun Biol 4:1247. https://doi.org/10.1038/s42003-021-02765-z | LEAK OXPHOS ET | N NS | Permeabilized tissue | Mouse | Endothelial;epithelial;mesothelial cell |
Yardeni 2021 Proc Natl Acad Sci U S A | 2021 | Yardeni T, Cristancho AG, McCoy AJ, Schaefer PM, McManus MJ, Marsh ED, Wallace DC (2021) An mtDNA mutant mouse demonstrates that mitochondrial deficiency can result in autism endophenotypes. Proc Natl Acad Sci U S A 118:e2021429118. | LEAK OXPHOS ET | N S NS ROX | Homogenate | Mouse | Nervous system |
Daura 2021 Neurobiol Dis | 2021 | Daura E, Tegelberg S, Yoshihara M, Jackson C, Simonetti F, Aksentjeff K, Ezer S, Hakala P, Katayama S, Kere J, Lehesjoki AE, Joensuu T (2021) Cystatin B-deficiency triggers ectopic histone H3 tail cleavage during neurogenesis. Neurobiol Dis 156:105418. | LEAK OXPHOS ET | N CIV NS | Permeabilized cells | Mouse | Stem cells Nervous system |
Santana-Roman 2021 Insects | 2021 | Santana-Román ME, Maycotte P, Uribe-Carvajal S, Uribe-Alvarez C, Alvarado-Medina N, Khan M, Siddiqui A, Pando-Robles V (2021) Monitoring mitochondrial function in Aedes albopictus C6/36 cell line during dengue virus infection. Insects 12:934. | LEAK OXPHOS ET | S | Permeabilized cells | ||
Tonnesen 2021 Mol Cell Biochem | 2021 | Tonnesen PT, Hjortbak MV, Lassen TR, Seefeldt JM, Bøtker HE, Jespersen NR (2021) Myocardial salvage by succinate dehydrogenase inhibition in ischemia-reperfusion injury depends on diabetes stage in rats. Mol Cell Biochem 476:2675-84. | LEAK OXPHOS | F N | Permeabilized tissue | Rat | Heart |
Prieto-Carrasco 2021 Biology (Basel) | 2021 | Prieto-Carrasco R, Silva-Palacios A, Rojas-Morales P, Aparicio-Trejo OE, Medina-Reyes EI, Hernandez-Cruz EY, Sanchez-Garibay C, Salinas-Lara C, Pavon N, Roldan FJ, Zazueta C, Tapia E, Pedraza-Chaverri J (2021) Unilateral ureteral obstruction for 28 days in rats is not associated with changes in cardiac function or alterations in mitochondrial function. Biology (Basel) 10:671. | LEAK OXPHOS ET | N S ROX | Isolated mitochondria | Rat | Heart |
Dall 2021 J Biol Chem | 2021 | Dall M, Hassing AS, Niu L, Nielsen TS, Ingerslev LR, Sulek K, Trammell SAJ, Gillum MP, Barrès R, Larsen S, Poulsen SS, Mann M, Ørskov C, Treebak JT (2021) Hepatocyte-specific perturbation of NAD+ biosynthetic pathways in mice induces reversible nonalcoholic steatohepatitis-like phenotypes. J Biol Chem 297:101388. | LEAK OXPHOS ET | N NS | Intact cells | Mouse | Liver |
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Drake 2021 Proc Natl Acad Sci U S A | 2021 | Drake JC, Wilson RJ, Laker RC, Guan Y, Spaulding HR, Nichenko AS, Shen W, Shang H, Dorn MV, Huang K, Zhang M, Bandara AB, Brisendine MH, Kashatus JA, Sharma PR, Young A, Gautam J, Cao R, Wallrabe H, Chang PA, Wong M, Desjardins EM, Hawley SA, Christ GJ, Kashatus DF, Miller CL, Wolf MJ, Periasamy A, Steinberg GR, Hardie DG, Yan Z (2021) Mitochondria-localized AMPK responds to local energetics and contributes to exercise and energetic stress-induced mitophagy. Proc Natl Acad Sci U S A 118:e2025932118. | LEAK OXPHOS ET | N S NS | Permeabilized tissue | Mouse | Skeletal muscle |
Cheng 2021 Comp Biochem Physiol B Biochem Mol Biol | 2021 | Cheng H, Munro D, Huynh K, Pamenter ME (2021) Naked mole-rat skeletal muscle mitochondria exhibit minimal functional plasticity in acute or chronic hypoxia. Comp Biochem Physiol B Biochem Mol Biol 255:110596. | OXPHOS ET LEAK | F N S CIV NS ROX | Isolated mitochondria | Other mammals | Skeletal muscle |
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Nambu 2021 Cardiovasc Res | 2021 | Nambu H, Takada S, Maekawa S, Matsumoto J, Kakutani N, Furihata T, Shirakawa R, Katayama T, Nakajima T, Yamanashi K, Obata Y, Nakano I, Tsuda M, Saito A, Fukushima A, Yokota T, Nio-Kobayashi J, Yasui H, Higashikawa K, Kuge Y, Anzai T, Sabe H, Kinugawa S (2021) Inhibition of xanthine oxidase in the acute phase of myocardial infarction prevents skeletal muscle abnormalities and exercise intolerance. Cardiovasc Res 117:805-19. | LEAK OXPHOS | Permeabilized tissue | Mouse | Skeletal muscle | |
Dorigatti 2021 Geroscience | 2021 | Dorigatti JD, Thyne KM, Ginsburg BC, Salmon AB (2021) Beta-guanidinopropionic acid has age-specific effects on markers of health and function in mice. Geroscience 43:1497-511. | LEAK OXPHOS ET | N S NS ROX F | Permeabilized tissue | Mouse | Skeletal muscle |
Zhang 2021 Pharmaceutics | 2021 | Zhang H, Zhang A, Gupte AA, Hamilton DJ (2021) Plumbagin elicits cell-specific cytotoxic effects and metabolic responses in melanoma cells. Pharmaceutics 13:706. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Intact cells | Human | Endothelial;epithelial;mesothelial cell Other cell lines |
Connell 2021 J Nutr | 2021 | Connell NJ, Grevendonk L, Fealy CE, Moonen-Kornips E, Bruls YMH, Schrauwen-Hinderling VB, de Vogel J, Hageman R, Geurts J, Zapata-Perez R, Houtkooper RH, Havekes B, Hoeks J, Schrauwen P (2021) NAD+-precursor supplementation with L-tryptophan, nicotinic acid, and nicotinamide does not affect mitochondrial function or skeletal muscle function in physically compromised older adults. J Nutr 151:2917-31 | LEAK OXPHOS ET | F N NS | Permeabilized tissue | Human | Skeletal muscle |
Trinity 2021 J Appl Physiol | 2021 | Trinity JD, Craig JC, Fermoyle CC, McKenzie AI, Lewis MT, Park SH, Rondina MT, Richardson RS (2021) Impact of presymptomatic COVID-19 on vascular and skeletal muscle function: a case study. J Appl Physiol (1985) 130:1961-70. | LEAK OXPHOS | N S NS | Permeabilized tissue | Human | Skeletal muscle |
Wuest 2021 Int J Mol Sci | 2021 | Wüst RCI, Coolen BF, Held NM, Daal MRR, Alizadeh Tazehkandi V, Baks-Te Bulte L, Wiersma M, Kuster DWD, Brundel BJJM, van Weeghel M, Strijkers GJ, Houtkooper RH (2021) The antibiotic doxycycline impairs cardiac mitochondrial and contractile function. Int J Mol Sci 22:4100. | LEAK OXPHOS ET | N S NS ROX | Permeabilized tissue | Mouse | Heart |
Figueira 2021 Arch Biochem Biophys | 2021 | Figueira TR, Francisco A, Ronchi JA, Dos Santos GRRM, Santos WD, Treberg JR, Castilho RF (2021) NADPH supply and the contribution of NAD(P)+ transhydrogenase (NNT) to H2O2 balance in skeletal muscle mitochondria. Arch Biochem Biophys 707:108934. | LEAK OXPHOS ET | N F | Isolated mitochondria | Mouse | Skeletal muscle |
Jasz 2021 J Cell Mol Med | 2021 | Jász DK, Szilágyi ÁL, Tuboly E, Baráth B, Márton AR, Varga P, Varga G, Érces D, Mohácsi Á, Szabó A, Bozó R, Gömöri K, Görbe A, Boros M, Hartmann P (2021) Reduction in hypoxia-reoxygenation-induced myocardial mitochondrial damage with exogenous methane. https://doi.org/10.1111/jcmm.16498 | LEAK ROUTINE OXPHOS ET | S ROX | Permeabilized cells Isolated mitochondria | Rat | Heart |
Braga 2021 Sci Rep | 2021 | Braga RR, Crisol BM, Brícola RS, Sant'ana MR, Nakandakari SCBR, Costa SO, Prada PO, da Silva ASR, Moura LP, Pauli JR, Cintra DE, Ropelle ER (2021) Exercise alters the mitochondrial proteostasis and induces the mitonuclear imbalance and UPRmt in the hypothalamus of mice. Sci Rep 11:3813. | LEAK OXPHOS ET | N NS | Isolated mitochondria | Mouse | Nervous system |
Goncalves 2021 Redox Biol | 2021 | Goncalves LS, Sales LP, Saito TR, Campos JC, Fernandes AL, Natali J, Jensen L, Arnold A, Ramalho L, Bechara LRG, Esteca MV, Correa I, Sant'Anna D, Ceroni A, Michelini LC, Gualano B, Teodoro W, Carvalho VH, Vargas BS, Medeiros MHG, Baptista IL, Irigoyen MC, Sale C, Ferreira JCB, Artioli GG (2021) Histidine dipeptides are key regulators of excitation-contraction coupling in cardiac muscle: evidence from a novel CARNS1 knockout rat model. Redox Biol 44:102016. | LEAK OXPHOS ET | NS | Isolated mitochondria | Rat | Heart |
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Dubinin 2021 Membranes (Basel) | 2021 | Dubinin MV, Semenova AA, Nedopekina DA, Davletshin EV, Spivak AY, Belosludtsev KN (2021) Effect of F16-betulin conjugate on mitochondrial membranes and its role in cell death initiation. Membranes (Basel) 11:352. | LEAK OXPHOS ET | N S | Isolated mitochondria | Rat | Liver |
Hodges 2021 J Biol Chem | 2021 | Hodges WT, Jarasvaraparn C, Ferguson D, Griffett K, Gill LE, Chen Y, Ilagan MXG, Hegazy L, Elgendy B, Cho K, Patti GJ, McCommis KS, Finck BN (2021) Mitochondrial pyruvate carrier inhibitors improve metabolic parameters in diet-induced obese mice. J Biol Chem 298:101554. | OXPHOS | N NS | Isolated mitochondria | Mouse | Heart |
Knapp-Wilson 2021 bioRxiv | 2021 | Knapp-Wilson A, Pereira GC, Buzzard E, Richardson A, Corey RA, Neal C, Verkade P, Halestrap AP, Gold VAM, Kuwabara P, Collinson I (2021) Maintenance of complex I and respiratory super-complexes by NDUF-11 is essential for respiratory function, mitochondrial structure and health in C. elegans. bioRxiv doi: https://doi.org/10.1101/2021.01.06.425530. | LEAK OXPHOS | N S | Isolated mitochondria | Caenorhabditis elegans | |
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Bastos Sant'Anna Silva 2021 Cancers (Basel) | 2021 | Bastos Sant'Anna Silva AC, Perez Valencia JA, Sciacovelli M, Lalou C, Sarlak S, Tronci L, Nikitopoulou E, Meszaros AT, Frezza C, Rossignol R, Gnaiger E, Klocker H (2021) Succinate anaplerosis has an onco-driving potential in prostate cancer cells. https://doi.org/10.3390/cancers13071727 | LEAK ROUTINE OXPHOS | S ROX | Permeabilized cells Intact cells | Human | Genital |
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Poles 2021 Front Immunol | 2021 | Poles MZ, Nászai A, Gulácsi L, Czakó BL, Gál KG, Glenz RJ, Dookhun D, Rutai A, Tallósy SP, Szabó A, Lőrinczi B, Szatmári I, Fülöp F, Vécsei L, Boros M, Juhász L, Kaszaki J (2021) Kynurenic acid and its synthetic derivatives protect against sepsis-associated neutrophil activation and brain mitochondrial dysfunction in rats. Front Immunol 12:717157. https://doi.org/10.3389/fimmu.2021.717157 | OXPHOS | NS | Homogenate | Rat | Nervous system |
Bandara 2021 Mitochondrion | 2021 | Bandara AB, Drake JC, James CC, Smyth JW, Brown DA (2021) Complex I protein NDUFS2 is vital for growth, ROS generation, membrane integrity, apoptosis, and mitochondrial energetics. Mitochondrion 58:160-68. | LEAK OXPHOS ET | N S | Permeabilized cells | Human | HEK |
Leduc-Gaudet 2021 bioRxiv | 2021 | Leduc-Gaudet JP, Miguez K, Marina Cefis M, Moamer A, Chaffer TJ, Faitg J, Reynaud O, Broering FE, Shams A, Mayaki D, Huck L, Sandri M, Gouspillou G, Hussain SNA (2021) Role of autophagy in sepsis-induced skeletal muscle dysfunction, whole-body metabolism, and survival. bioRxiv doi: https://doi.org/10.1101/2021.08.05.455081. | LEAK OXPHOS | N | Permeabilized tissue | Mouse | Skeletal muscle |
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Davies 2021 FASEB J | 2021 | Davies KL, Smith DJ, El-Bacha T, Stewart ME, Easwaran A, Wooding PFP, Forhead AJ, Murray AJ, Fowden AL, Camm EJ (2021) Development of cerebral mitochondrial respiratory function is impaired by thyroid hormone deficiency before birth in a region-specific manner. FASEB J 35:21591. | LEAK OXPHOS | N S NS | Homogenate | Other mammals | Nervous system |
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Liang 2021 Biomed Pharmacother | 2021 | Liang L, Zhang G, Cheng C, Li H, Jin T, Su C, Xiao Y, Bradley J, Peberdy MA, Ornato JP, Mangino MJ, Tang W (2021) High-resolution respirometry for evaluation of mitochondrial function on brain and heart homogenates in a rat model of cardiac arrest and cardiopulmonary resuscitation. Biomed Pharmacother 142:111935. | LEAK OXPHOS ROUTINE | N S CIV ROX | Homogenate | Rat | Heart Nervous system |
Christiansen 2021 Sci Rep | 2021 | Christiansen LB, Dohlmann TL, Ludvigsen TP, Parfieniuk E, Ciborowski M, Szczerbinski L, Kretowski A, Desler C, Tiano L, Orlando P, Martinussen T, Olsen LH, Larsen S (2021) Atorvastatin impairs liver mitochondrial function in obese Göttingen Minipigs but heart and skeletal muscle are not affected. Sci Rep 11:2167. | LEAK OXPHOS ET | F N S CIV NS | Permeabilized tissue | Pig | Heart Skeletal muscle Liver |
Hamm 2021 Mol Ther Methods Clin Dev | 2021 | Hamm SE, Fathalikhani DD, Bukovec KE, Addington AK, Zhang H, Perry JB, McMillan RP, Lawlor MW, Prom MJ, Vanden Avond MA, Kumar SN, Coleman KE, Dupont JB, Mack DL, Brown DA, Morris CA, Gonzalez JP, Grange RW (2023) Voluntary wheel running complements microdystrophin gene therapy to improve muscle function in mdx mice. https://doi.org/10.1016/j.omtm.2021.02.024 | LEAK OXPHOS | N NS | Permeabilized tissue | Mouse | Skeletal muscle |
Vandenberg 2021 Neurochem Int | 2021 | Vandenberg GG, Dawson NJ, Head A, Scott GR, Scott AL (2021) Astrocyte-mediated disruption of ROS homeostasis in Fragile X mouse model. Neurochem Int 146:105036. | LEAK OXPHOS | N CIV NS | Permeabilized cells | Mouse | Nervous system |
Apostolopoulou 2021 Sci Adv | 2021 | Apostolopoulou M, Mastrototaro L, Hartwig S, Pesta D, Straßburger K, de Filippo E, Jelenik T, Karusheva Y, Gancheva S, Markgraf D, Herder C, Nair KS, Reichert AS, Lehr S, Müssig K, Al-Hasani H, Szendroedi J, Roden M (2021) Metabolic responsiveness to training depends on insulin sensitivity and protein content of exosomes in insulin-resistant males. https://doi.org/10.1126/sciadv.abi9551 | LEAK OXPHOS ET | N NS ROX | Permeabilized tissue | Human | Skeletal muscle |
Pharaoh 2021 JCSM Rapid Commun | 2021 | Pharaoh G, Brown J, Ranjit R, Ungvari Z, Van Remmen H (2021) Reduced adenosine diphosphate sensitivity in skeletal muscle mitochondria increases reactive oxygen species production in mouse models of aging and oxidative stress but not denervation. https://doi.org/10.1002/rco2.29 | LEAK OXPHOS | N S CIV NS ROX | Permeabilized tissue | Mouse | Skeletal muscle |
Kaspar 2021 Sci Adv | 2021 | Kaspar S, Oertlin C, Szczepanowska K, Kukat A, Senft K, Lucas C, Brodesser S, Hatzoglou M, Larsson O, Topisirovic I, Trifunovic A (2021) Adaptation to mitochondrial stress requires CHOP-directed tuning of ISR. Sci Adv 7:0971. | LEAK OXPHOS ET | N S NS ROX | Isolated mitochondria | Mouse | Heart |
Gupta 2021 Sci Rep | 2021 | Gupta MK, Sahu A, Sun Y, Mohan ML, Kumar A, Zalavadia A, Wang X, Martelli EE, Stenson K, Witherow CP, Drazba J, Dasarathy S, Naga Prasad SV (2021) Cardiac expression of microRNA-7 is associated with adverse cardiac remodeling. Sci Rep 11:22018. | LEAK OXPHOS ET | N S CIV NS ROX | Isolated mitochondria | Mouse | Heart |
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Mazzoli 2021 Antioxidants (Basel) | 2021 | Mazzoli A, Spagnuolo MS, Nazzaro M, Gatto C, Iossa S, Cigliano L (2021) Fructose removal from the diet reverses inflammation, mitochondrial dysfunction, and oxidative stress in hippocampus. Antioxidants (Basel) 10:487. | LEAK OXPHOS ET | N S NS ROX | Homogenate | Rat | Nervous system |
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Cruz 2020 Drug Alcohol Depend | 2020 | Cruz JV, Maba IK, Correia D, Kaziuk FD, Cadena SMSC, Zampronio AR (2020) Intermittent binge-like ethanol exposure during adolescence attenuates the febrile response by reducing brown adipose tissue thermogenesis in rats. Drug Alcohol Depend 209:107904. | LEAK OXPHOS | N | Isolated mitochondria | Rat | Fat |
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Hosmann 2020 Acta Neurochir (Wien) | 2020 | Hosmann A, Milivojev N, Dumitrescu S, Reinprecht A, Weidinger A, Kozlov AV (2020) Cerebral nitric oxide and mitochondrial function in patients suffering aneurysmal subarachnoid hemorrhage-a translational approach. Acta Neurochir (Wien) 163:139-49. | OXPHOS | N S CIV ROX | Homogenate | Rat | Nervous system |
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Hayes 2020 Nutrients | 2020 | Hayes P, Fergus C, Ghanim M, Cirzi C, Burtnyak L, McGrenaghan CJ, Tuorto F, Nolan DP, Kelly VP (2020) Queuine micronutrient deficiency promotes Warburg metabolism and reversal of the mitochondrial ATP synthase in HeLa cells. Nutrients 12:E871. | LEAK ROUTINE OXPHOS ET | N S Gp CIV ROX | Permeabilized cells Intact cells | Human | HeLa |
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Szibor 2020 J Cell Mol Med | 2020 | Szibor M, Schreckenberg R, Gizatullina Z, Dufour E, Wiesnet M, Dhandapani PK, Debska-Vielhaber G, Heidler J, Wittig I, Nyman TA, Gaertner U, Hall AR, Pell V, Viscomi C, Krieg T, Murphy MP, Braun T, Gellerich FN, Schlueter KD, Jacobs HT(2020) Respiratory chain signalling is essential for adaptive remodelling following cardiac ischaemia. J Cell Mol Med 24:3534-48. | LEAK OXPHOS | N S CIV | Permeabilized tissue Isolated mitochondria | Mouse | Heart |
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Frambach 2020 Biochim Biophys Acta Mol Basis Dis | 2020 | Frambach SJCM, van de Wal MAE, van den Broek PHH, Smeitink JAM, Russel FGM, de Haas R, Schirris TJJ (2020) Effects of clofibrate and KH176 on life span and motor function in mitochondrial complex I-deficient mice. Biochim Biophys Acta Mol Basis Dis 1866:165727. | LEAK OXPHOS | F N S Gp CIV Other combinations ROX | Permeabilized tissue | Mouse | Skeletal muscle |
Krabbendam 2020 Cell Death Dis | 2020 | Krabbendam IE, Honrath B, Dilberger B, Iannetti EF, Branicky RS, Meyer T, Evers B, Dekker FJ, Koopman WJH, Beyrath J, Bano D, Schmidt M, Bakker BM, Hekimi S, Culmsee C, Eckert GP, Dolga AM (2020) SK channel-mediated metabolic escape to glycolysis inhibits ferroptosis and supports stress resistance in C. elegans. Cell Death Dis 11:263. | LEAK OXPHOS | N S | Isolated mitochondria | Mouse | Nervous system |
Brum 2020 Mol Neurobiol | 2020 | Brum EDS, Fialho MFP, Fischer SPM, Hartmann DD, Gonçalves DF, Scussel R, Machado-de-Ávila RA, Dalla Corte CL, Soares FAA, Oliveira SM (2020) Relevance of mitochondrial dysfunction in the reserpine-induced experimental fibromyalgia model. Mol Neurobiol 57:4202-17. | LEAK OXPHOS ET | N S NS ROX | Permeabilized tissue Homogenate | Mouse | Skeletal muscle Nervous system |