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• O2k-Publications: Mouse
  ...:Publications]] [[Instrument and method::Oxygraph-2k]] [[Mammal and model::Mouse]] == O2k-Publications: Mouse - Abstracts ==
  1 KB (201 words) - 11:14, 11 November 2016
• Mouse control: Zoom
  |description=Select '''Mouse Control: Zoom''' in the Graph-menu or press [Ctrl+Z]. :::: If '''Mouse control: Zoom''' is enabled (instead of [[Mouse control: Mark]]) zooming into the graph is possible by doing the following:
  982 bytes (149 words) - 11:55, 25 March 2022
• Mouse control: Mark
  ...de is active by default, can be selected in the menu or by [Ctrl+M]. If '''Mouse control: Mark''' is enabled, specific sections of the experiment can be mar
  628 bytes (99 words) - 11:55, 25 March 2022
• MiPNet17.17 Amplex-Mouse-brain
  ...tocols]] O2k-Fluorometry: HRR and H₂O₂ production in mouse brain mitochondria. ...|Bioblast pdf]] »[http://www.bioblast.at/index.php/File:MiPNet17.17_Amplex-Mouse-brain.pdf Versions]
  828 bytes (117 words) - 10:54, 27 November 2019
• MiPNet18.05 Amplex-Mouse-heart
  ...tocols]] O2k-Fluorometry: HRR and H₂O<sub>2</Sub> production in mouse cardiac tissue homogenate. ...|Bioblast pdf]] »[http://www.bioblast.at/index.php/File:MiPNet18.05_Amplex-Mouse-heart.pdf Versions]
  1 KB (151 words) - 12:30, 25 October 2023
• Curr Protoc Mouse Biol
  ...entprotocols.onlinelibrary.wiley.com/journal/21612617 Current Protocols in Mouse Biology]
  122 bytes (13 words) - 15:01, 20 August 2019
• MiPNet20.06 Isolation of mouse heart mitochondria.
  48 bytes (3 words) - 14:59, 10 June 2015
• MiPNet20.06 Isolation of mouse heart mitochondria
  48 bytes (3 words) - 11:09, 27 April 2015
• Canto 2015 Curr Protoc Mouse Biol
  ...r mitochondrial characterization of ''ex vivo'' mouse tissues. Curr Protoc Mouse Biol 5:135-53. |journal=Curr Protoc Mouse Biol
  1 KB (141 words) - 17:11, 9 November 2017
• Cantó 2015 Curr Protoc Mouse Biol
  #REDIRECT [[Canto 2015 Curr Protoc Mouse Biol]]
  47 bytes (6 words) - 09:58, 13 November 2015
• O2k-Publications: Skeletal muscle - human vs mouse
  ...and method::Oxygraph-2k]] [[Mammal and model::Human]] [[Mammal and model::Mouse]] [[Tissue and cell::Skeletal muscle]] == O2k-Publications: Skeletal muscle - human vs mouse - Abstracts ==
  2 KB (214 words) - 16:04, 16 April 2018
• MiPNet17.15 PBI-Shredder Mouse-heart-brain-liver
  ...]] Tissue homogenates for diagnosis of mitochondrial respiratory function: Mouse heart, brain and liver. ...5) Tissue homogenates for diagnosis of mitochondrial respiratory function: Mouse heart, brain and liver. Mitochondr Physiol Network 17.15(04):1-6.
  1 KB (132 words) - 16:49, 17 October 2023

Page text matches

• Graph control - DatLab
  | description=A combination of mouse and keyboard commands provides convenient control of graphs in DatLab 8. === Mouse ===
  2 KB (267 words) - 13:04, 24 March 2022
• Canto 2015 Curr Protoc Mouse Biol
  ...r mitochondrial characterization of ''ex vivo'' mouse tissues. Curr Protoc Mouse Biol 5:135-53. |journal=Curr Protoc Mouse Biol
  1 KB (141 words) - 17:11, 9 November 2017
• Mouse control: Zoom
  |description=Select '''Mouse Control: Zoom''' in the Graph-menu or press [Ctrl+Z]. :::: If '''Mouse control: Zoom''' is enabled (instead of [[Mouse control: Mark]]) zooming into the graph is possible by doing the following:
  982 bytes (149 words) - 11:55, 25 March 2022
• MiPNet18.05
  #REDIRECT [[MiPNet18.05 Amplex-Mouse-heart]]
  44 bytes (3 words) - 08:42, 18 October 2013
• MiPNet12.01 Suppl T-issue
  ...ink=O2k-Protocols|O2k-Protocols contents]] MitoPathways at the Q-junction: mouse skeletal muscle fibers. |abstract= Oroboros (2018) MitoPathways at the Q-junction: mouse skeletal muscle fibers. Mitochondr Physiol Network 12.01(03): Suppl T-issue
  931 bytes (121 words) - 12:30, 4 December 2019
• Curr Protoc Mouse Biol
  ...entprotocols.onlinelibrary.wiley.com/journal/21612617 Current Protocols in Mouse Biology]
  122 bytes (13 words) - 15:01, 20 August 2019
• MiPNet17.15
  #REDIRECT [[MiPNet17.15 PBI-Shredder Mouse-heart-brain-liver]]
  62 bytes (4 words) - 08:56, 19 December 2016
• MiPNet20.06 IsolationMouseHeart-mt
  ...t|80px|link=O2k-Protocols|O2k-Protocols]]Laboratory protocol: isolation of mouse heart mitochondria. ...omlodi T, Cardoso LHD, Gnaiger E (2021) Laboratory protocol: Isolation of mouse heart mitochondria. Mitochondr Physiol Network 20.06(02):1-4.
  1 KB (135 words) - 07:10, 20 December 2023
• MiPNet18.05 Amplex-Mouse-heart
  ...tocols]] O2k-Fluorometry: HRR and H₂O<sub>2</Sub> production in mouse cardiac tissue homogenate. ...|Bioblast pdf]] »[http://www.bioblast.at/index.php/File:MiPNet18.05_Amplex-Mouse-heart.pdf Versions]
  1 KB (151 words) - 12:30, 25 October 2023
• Jacobs 2013b Exp Physiol
  |title=Jacobs R, Díaz V, Meinild AK, Gassmann M, Lundby C (2012) The C57Bl/6 mouse serves as a suitable model of human skeletal muscle mitochondrial function. ...t qualitative differences in mitochondria function exist between different mouse skeletal muscles types when respiratory capacity is normalized to mitochond
  2 KB (333 words) - 12:06, 28 March 2018
• O2k-Publications: Mouse
  ...:Publications]] [[Instrument and method::Oxygraph-2k]] [[Mammal and model::Mouse]] == O2k-Publications: Mouse - Abstracts ==
  1 KB (201 words) - 11:14, 11 November 2016
• Goetzman 2011 Prog Mol Biol Transl Sci
  |title=Goetzman ES (2011) Modeling disorders of fatty acid metabolism in the mouse. Prog Mol Biol Transl Sci 100:389-417. https://doi.org/10.1016/B978-0-12-38 ...n-3. Finally, nongenetic means of manipulating fatty acid oxidation in the mouse are discussed, in particular the various chemical inhibitors that have been
  2 KB (276 words) - 16:16, 29 October 2023
• Long 2019 Methods Mol Biol
  ...(2019) Assessing mitochondrial bioenergetics in isolated mitochondria from mouse heart tissues using Oroboros Oxygraph-2k. Methods Mol Biol 1966:237-46. ...ng high-resolution respirometry on mitochondria extracted from adult whole mouse heart using the Oroboros Oxygraph-2k system. The method provides detailed p
  1 KB (191 words) - 18:21, 29 February 2020
• Sparks 2015 Fatty Acid Oxidation O2k-Network Discussion Forum
  |abstract=We routinely (up to 4 human and mouse studies) measure respiration supported by glycolytic and fatty acid substra |organism=Human, Mouse
  732 bytes (99 words) - 11:30, 8 November 2016
• MiPNet17.17 Amplex-Mouse-brain
  ...tocols]] O2k-Fluorometry: HRR and H₂O₂ production in mouse brain mitochondria. ...|Bioblast pdf]] »[http://www.bioblast.at/index.php/File:MiPNet17.17_Amplex-Mouse-brain.pdf Versions]
  828 bytes (117 words) - 10:54, 27 November 2019
• Kucera 2016 Drug Chem Toxicol
  ...otková H, Sobotka O, Červinková Z (2016) Acetaminophen toxicity in rat and mouse hepatocytes ''in vitro''. Drug Chem Toxicol 40:448-56. The aim of our work was to compare hepatotoxicity of APAP in rat and mouse hepatocytes in primary cultures.
  3 KB (343 words) - 12:08, 18 January 2019
• Ost 2015 Fatty Acid Oxidation O2k-Network Discussion Forum
  |abstract=Right now we´re using octanoyl carnitine (OC) when examining mouse skeletal muscle permeabilized fiber respiration. We ususally start with Mal |organism=Mouse
  734 bytes (105 words) - 11:27, 8 November 2016
• O2k-Publications: Skeletal muscle - human vs mouse
  ...and method::Oxygraph-2k]] [[Mammal and model::Human]] [[Mammal and model::Mouse]] [[Tissue and cell::Skeletal muscle]] == O2k-Publications: Skeletal muscle - human vs mouse - Abstracts ==
  2 KB (214 words) - 16:04, 16 April 2018
• Herbst 2016 Appl Physiol Nutr Metab
  ...oway GP (2016) Exercise increases mitochondrial glutamate oxidation in the mouse cerebral cortex. Appl Physiol Nutr Metab 41:799-801. ...act of acute exercise on stimulating mitochondrial respiratory function in mouse cerebral cortex. Where pyruvate-stimulated respiration was not affected by
  1 KB (173 words) - 17:24, 7 November 2016
• Garcia-Roves 2016b Abstract MitoFit Science Camp 2016
  ...olution respirometry in permeabilized skinned muscle fibers from different mouse models. ...ventions to induce obesity-related type 2 diabetes or genetically modified mouse models are the main experimental approaches. Our overall interest is to ass
  2 KB (209 words) - 08:56, 1 July 2016
• Pichova A
  ...n mitochondria in intestinal system and marginally in another tissues from mouse (conventional and gnotobiological).
  1 KB (176 words) - 15:40, 6 September 2022
• Can 2018 IOC130
  |title=Mitochondrial dysfunction in a mouse model of Rett syndrome. |organism=Mouse
  800 bytes (104 words) - 10:52, 28 May 2018
• Lindfors 2011 Proc Natl Acad Sci U S A
  ...thalamic mitochondrial dysfunction associated with anorexia in the anx/anx mouse. Proc Natl Acad Sci U S A 108:18108-13. ...uggest that the anorexia and hypothalamic neurodegeneration of the anx/anx mouse are associated with dysfunction of mitochondrial Complex I.
  2 KB (312 words) - 15:51, 17 February 2015
• Herbst 2015 J Physiol
  ...n situ enables multi-region analysis of mitochondrial function in a single mouse brain. J Physiol 593:787-801. ...as the majority of genetic models used for unique approaches exist in the mouse model.
  2 KB (303 words) - 17:24, 7 November 2016
• Chinopoulos 2011 Methods Mol Biol
  ...Isolation and functional assessment of mitochondria from small amounts of mouse brain tissue. Methods Mol Biol 793:311-24. ...matic and functional assays, thereby eliminating the necessity for pooling mouse brain tissue. We also include a method of measuring ADP-ATP exchange rate a
  2 KB (311 words) - 17:51, 22 February 2021
• Tsouka 2024 Commun Med (Lond)
  ...abolic pathway analysis reveals similar alterations in lipid metabolism in mouse MASH model and human. Commun Med (Lond) 4:39. https://doi.org/10.1038/s4385 ...develop treatment strategies. Through meta-analysis of currently proposed mouse models, we hypothesized that a diet- and chemical-induced MASH model closel
  3 KB (363 words) - 14:12, 13 March 2024
• MiPNet17.15 PBI-Shredder Mouse-heart-brain-liver
  ...]] Tissue homogenates for diagnosis of mitochondrial respiratory function: Mouse heart, brain and liver. ...5) Tissue homogenates for diagnosis of mitochondrial respiratory function: Mouse heart, brain and liver. Mitochondr Physiol Network 17.15(04):1-6.
  1 KB (132 words) - 16:49, 17 October 2023
• Bonsignore 2015 Mech Ageing Dev
  ...l ROS and subsequent DNA damage. These studies position the NRMT1 knockout mouse as a useful new system for studying the effects of genomic instability and |organism=Mouse
  2 KB (299 words) - 16:59, 9 November 2017
• Cotter Matthew
  ...pring mitochondrial function, in placenta, PBMCs, and platelets (human and mouse). ...itochondrial function, in skeletal muscle, PBMCs, and platelets (human and mouse).
  965 bytes (125 words) - 09:11, 4 March 2020
• Doerrier 2022 MitoFit NADH
  ...NAD-redox state, high-resolution respirometry HRR, isolated mitochondria, mouse liver mitochondria, SUIT protocols, N-pathway |organism=Mouse
  946 bytes (114 words) - 10:06, 3 May 2022
• Bundgaard 2019 Sci Rep
  ...concentrations and succinate/fumarate ratios were lower in turtle than in mouse heart, limiting the driving force for production of reactive oxygen species |organism=Mouse, Reptiles
  2 KB (303 words) - 21:36, 13 February 2022
• Krumschnabel 2016a Abstract MitoFit Science Camp 2016
  ...It is shown that different mt preparations may result in almost identical (mouse) or at least comparable (beef) mitochondrial coupling control and respirato |organism=Mouse
  2 KB (201 words) - 18:41, 10 January 2022
• Mufazalov 2009 Mol Biol (Mosk)
  ...DV, Skulachev VP, Nedospasov SA (2009) Preparation and characterization of mouse embryonic fibroblasts with K72W mutation in somatic cytochrome ''c'' gene. |abstract=Mouse embryonic fibroblasts (MEF) with point mutation in somatic cytochrome ''c''
  2 KB (212 words) - 15:40, 9 November 2016
• Tripp FD
  |institution=Mouse Metabolic Phenotyping Center
  347 bytes (41 words) - 14:25, 14 April 2015
• Kassassir 2016 Flow Cytometry - Select Topics
  ...and disadvantages of flow cytometry as a method of choice in the study of mouse and rat platelets. Flow Cytometry - Select Topics Chapter 3:31-83. .... We hope that our paper may further facilitate other researchers to study mouse and rat platelets with the use of the most optimal and the least artefact-p
  2 KB (301 words) - 14:49, 27 March 2018
• Freyer 2010 Nucleic Acids Res
  ...tafsson CM, Larsson NG (2010) Maintenance of respiratory chain function in mouse hearts with severely impaired mtDNA transcription. Nucleic Acids Res 38:657 ...shed mtDNA transcription caused by tissue-specific knockout of TFAM in the mouse heart leads to early onset of a severe mitochondrial cardiomyopathy with le
  2 KB (305 words) - 16:34, 7 November 2016
• Du 2015 J Biol Chem
  ...) Phototransduction influences metabolic flux and nucleotide metabolism in mouse retina. J Biol Chem 291:4698-710. ...is not coupled tightly to ATP consumption. By analyzing metabolic flux in mouse retinas, we also found that phototransduction slows metabolic flux through
  2 KB (294 words) - 13:17, 10 March 2020
• Rubio-Villena 2018 Hum Mol Genet
  ...In addition, we have observed that primary cultures of astrocytes from LD mouse models accumulate higher levels of glycogen than controls. These results su |organism=Mouse
  2 KB (280 words) - 16:32, 27 March 2018
• Valenti 2014 Anal Biochem
  ...ial functional integrity in mitochondria isolated from small cryopreserved mouse brain areas. Anal Biochem 444:25-31. ...ained in crude mitochondria isolated from different areas of cryopreserved mouse brain samples. Long-term cryopreservation of small brain areas from which i
  2 KB (283 words) - 16:22, 13 November 2017
• Barksdale 2010 FASEB J
  ..., Melendez-Ferro M, Roberts RC, Bijur GN (2010) Mitochondrial viability in mouse and human postmortem brain. FASEB J 24:3590-9. ...ith increasing postmortem intervals. Mitochondria isolated from postmortem mouse brains maintain the ability to produce ATP, but rates of production decreas
  2 KB (276 words) - 15:50, 15 June 2015
• Onopiuk 2009 Biochem Biophys Res Commun
  ...K (2009) Mutation in dystrophin-encoding gene affects energy metabolism in mouse myoblasts. Biochem Biophys Res Commun 386:463-6. ...he dystrophic and control myoblasts used were derived from a common inbred mouse strain and the only difference between them is a point mutation in the dyst
  2 KB (259 words) - 17:41, 25 November 2015
• Halsne 2012 DNA Repair (Amst)
  ...ack of the DNA glycosylases MYH and OGG1 in the cancer prone double mutant mouse does not increase mitochondrial DNA mutagenesis. DNA Repair (Amst) 11:278-8 ...acity was observed in brain mitochondria from the adult myh(-/-)/ogg1(-/-) mouse. The reduced respiration capacity correlated with a specific reduction (-25
  2 KB (388 words) - 03:05, 1 March 2020
• Kim MiP2010
  ...mitochondrial nitric oxide (mtNO) and increase of ROS production in Spr-/- mouse which induced oxidative damage on mitochondrial function accompanied with m |organism=Mouse
  2 KB (312 words) - 15:45, 28 March 2018
• Pharaoh 2021 JCSM Rapid Commun
  ...eletal muscle mitochondria increases reactive oxygen species production in mouse models of aging and oxidative stress but not denervation. https://doi.org/1 ...sensitivity) in aged human muscle. Here, we investigate ADP sensitivity in mouse muscle mitochondria.
  3 KB (401 words) - 16:23, 4 January 2023
• Farsijani N
  * High resolution respirometry of mouse kidney tissue
  353 bytes (40 words) - 17:33, 12 February 2018
• Garcia-Corzo 2011 Abstract Euromit 8
  |title=Generation of a mouse model of Coenzyme Q deficiency.
  263 bytes (35 words) - 16:59, 29 November 2016
• McElroy 2020 Cell Metab
  ...Chandel NS (2020) NAD+ regeneration rescues lifespan, but not ataxia, in a mouse model of brain mitochondrial Complex I dysfunction. Cell Metab 32:301-8.e6. ...cally prolong lifespan without significantly improving motor function in a mouse model of Leigh syndrome driven by the loss of NDUFS4, a subunit of mitochon
  2 KB (235 words) - 23:40, 23 April 2023
• Klaus S
  ...imagine working on a joint review article. Next to examining muscle from mouse models, we are studying biopsies from human heart muscle and liver, but th ...imagine working on a common review article. In addition to muscle from the mouse, we are currently investigating human heart muscle and liver biopsy, but we
  2 KB (228 words) - 10:51, 9 July 2018
• Lehto 2022 Neurochem Res
  ...xybutyrate improves mitochondrial function after transient ischemia in the mouse. https://doi.org/10.1007/s11064-022-03637-6 ...he neurological score determined after 24 h. In isolated mitochondria from mouse brain, oxygen consumption by the complexes I, II and IV was reduced immedia
  2 KB (274 words) - 14:10, 2 May 2023
• Garratt 2014 Proc Natl Acad Sci U S A
  ...f superoxide dismutase deficiency not observed in previous studies of this mouse model. This range included impaired bioenergetic function, which was undete |organism=Mouse
  2 KB (287 words) - 14:18, 13 November 2017
• Keyboard shortcuts - DatLab
  ...s to allow for quick access to many functions and settings without using a mouse. ! Alt+Mouse
  3 KB (455 words) - 11:14, 25 March 2022
• Crombie 2015 Biochem Biophys Rep
  ...lation (OXPHOS) and phagocytosis. We showed that whilst the YG22R and YG8R mouse models display elements of retinal degeneration, they do not recapitulate t ...ia, Induced pluripotent stem cells, Retinal pigment epithelium, Human eye, Mouse models, Oxidative phosphorylation
  2 KB (282 words) - 17:27, 9 November 2017
• Fourcade 2014 Biochimie
  ...n efficacy at halting axonal degeneration and associated disability in the mouse, and thus offer therapeutic hope.
  2 KB (223 words) - 11:24, 9 March 2015
• Ahting 2009 Biochim Biophys Acta
  ...notype and reduced lifespan in heterozygous Tim23 knockout mice, the first mouse model of defective mitochondrial import. Biochim Biophys Acta 1787:371-76. ...he mitochondrial protein import machinery. We created a ''Tim23'' knockout mouse from a gene trap embryonic stem cell clone. Homozygous Tim23 mice were not
  2 KB (277 words) - 11:09, 18 October 2018
• Jelenik 2014 Diabetes
  ...Tissue-specific differences in the development of insulin resistance in a mouse model for type 1 diabetes. Diabetes 63:3856-67. ...distinct cellular mechanisms during the development of diabetes in the NOD mouse.
  2 KB (283 words) - 14:46, 13 November 2017
• Chang 2020 J Biol Chem
  ...ese findings provide evidence of metabolic defects in G2435R-RYR1 knock-in mouse muscle under basal conditions. Differences in metabolic profile could be th |keywords=Bioenergetics, Malignant hyperthermia, Mitochondrial metabolism, Mouse, Muscle physiology, Ryanodine receptor
  2 KB (348 words) - 19:28, 21 February 2022
• Lima 2021 Nat Metab
  ...fying selection to eliminate cells with mitochondrial defects during early mouse development. Nat Metab 3:1091-108. https://doi.org/10.1038/s42255-021-00422 ...hondrial function triggers cell competition. Moreover, we show that in the mouse embryo, cell competition eliminates cells with sequence changes in mt-Rnr1
  2 KB (315 words) - 15:27, 5 October 2023
• Karadayian 2015 Neuroscience
  ...hangover induces mitochondrial dysfunction and free radical production in mouse cerebellum. Neuroscience 304:47-59. ...t the physiopathological state of AH involves mitochondrial dysfunction in mouse cerebellum showing the long-lasting effects of acute EtOH exposure in the c
  2 KB (345 words) - 12:00, 11 July 2017
• Hagl 2015 Neurochem Int
  ...oved to be more efficient in preventing mitochondrial swelling in isolated mouse brain mitochondria and protecting PC12 cells from nitrosative stress than n |organism=Mouse
  2 KB (339 words) - 07:51, 21 February 2020
• McCourt 2016 PLOS ONE
  ...S, Elmér E, Björkqvist M (2016) White adipose tissue browning in the R6/2 mouse model of Huntington's disease. PLOS ONE 11:e0159870. ...ained from Q175 mice. In summary, for the first time, we here show that HD mouse WAT undergoes a process of browning, resulting in molecular and functional
  3 KB (423 words) - 15:16, 13 November 2017
• Wall 2006 Am J Physiol Heart Circ Physiol
  ...on complex proteins. Thus the cardioprotection observed in MKK6 transgenic mouse hearts may be partly due to decreased electron transport, which is potentia
  3 KB (385 words) - 10:40, 19 December 2023
• Vandenberg 2021 Neurochem Int
  ...tt AL (2021) Astrocyte-mediated disruption of ROS homeostasis in Fragile X mouse model. Neurochem Int 146:105036. ...antioxidant expression that may occur in FXS. Using the Fmr1 knockout (KO) mouse model, mitochondrial respiration and reactive oxygen species (ROS) emission
  2 KB (321 words) - 09:13, 11 August 2021
• Weber 2015 Fatty Acid Oxidation O2k-Network Discussion Forum
  |organism=Human, Mouse
  358 bytes (47 words) - 11:31, 8 November 2016
• Hagl 2014 J Alzheimers Dis b
  ...J, Eckert GP (2014) Curcumin micelles improve mitochondrial function in a mouse model of Alzheimer’s disease. J Alzheimers Dis 1:80-3. mouse model of AD (Thy1-APP751SL transgenic mice) after 3-
  2 KB (255 words) - 04:31, 12 February 2020
• Hogeboom 1950 J Biol Chem
  ...dehydrogenase and triphosphopyridine nucleotide-cytochrome c reductase of mouse liver. J Biol Chem 186:417-27.
  409 bytes (51 words) - 14:16, 27 May 2015
• Ferreira 2017 MiPschool Obergurgl
  ...x|Ferreira Luciana]] Doxorubicin toxicity and mitochondrial dysfunction in mouse induced pluripotent stem cells-derived cardiomyocytes.
  476 bytes (54 words) - 16:01, 12 January 2018
• Shum 2018 Thesis
  (CypD). Our CypD knockout mouse model has protected mitochondrial function our ovariectomy model in the CypD knockout mouse did not show any protection.
  2 KB (296 words) - 14:46, 6 August 2018
• Kamberov 2013 Cell
  ...ficance and potential adaptive role remain unclear. We generated a knockin mouse model and find that, as in humans, hair thickness is increased in EDAR370A |keywords=Population genetic analyses, Humanized mouse model, Human association study, Natural human gene variant
  2 KB (263 words) - 17:30, 25 February 2020
• Talati 2016 Am J Respir Crit Care Med
  ...2 mutation. Electron microscopy and metabolomic analysis were performed on mouse RVs. ...tabolomics analysis showed reduced indices of FAO. Using both mutant BMPR2 mouse RVs and cardiomyocytes, we found an increase in the uptake of (14)C-palmita
  3 KB (376 words) - 11:21, 3 August 2017
• Baekkerud 2015 Fatty Acid Oxidation O2k-Network Discussion Forum
  |organism=Mouse
  417 bytes (50 words) - 10:49, 8 November 2016
• Silva Ramos 2019 PLoS Genet
  ...oes not affect transcription. Furthermore, the profound mtDNA depletion in mouse hearts lacking OMM fusion is not caused by defective integrity or increased |organism=Mouse
  2 KB (330 words) - 15:17, 17 June 2019
• Wang 2011 J Neurochem
  ...a previously published procedure for isolating mitochondria from neonatal mouse brain (method A) with procedures adapted from those for adult rats (method |organism=Mouse, Rat
  2 KB (288 words) - 17:20, 31 January 2020
• Neviere 2015 Fatty Acid Oxidation O2k-Network Discussion Forum
  |organism=Human, Mouse
  411 bytes (53 words) - 16:41, 26 March 2018
• US OR Corvallis Robinson MM
  |keyword=Exercise, insulin resistance, obesity, humans, mouse model
  426 bytes (56 words) - 10:26, 14 December 2022
• Ceru 2010 J Biol Chem
  ...ficient mouse embryonic fibroblasts entered S phase earlier than wild type mouse embryonic fibroblasts. In contrast, increased expression of stefin B in the |organism=Mouse
  2 KB (300 words) - 14:47, 29 July 2016
• Zhang 2022 Mol Med Rep
  ...enyl‑1,2,3,6‑tetrahydropyridine on inducing chronic Parkinson's disease in mouse models. https://doi.org/10.3892/mmr.2022.12607 ...no significant differences in neurobehavior were observed between the two mouse models, the MPTP model reproduced the pathological features of PD more prec
  3 KB (478 words) - 12:56, 12 December 2022
• Kovarova 2015 Abstract MiP2015
  ...espiratory enzymes. This was achieved by investigating SURF1^-/- mouse tissues and fibroblasts in comparison with patient fibroblasts lacking SURF ...stigating of COX biogenesis in SURF1^+/+ and SURF1^-/- mouse fibroblasts and in control and SURF1 patient fibroblasts.
  5 KB (697 words) - 15:38, 9 November 2016
• Fedorov 2022 Naunyn Schmiedebergs Arch Pharmacol
  ...In the present work, we used mitochondria that were freshly isolated from mouse brain to test mitochondrial respiration and ATP synthesis in the presence o |organism=Mouse
  2 KB (289 words) - 19:17, 24 February 2023
• Mayayo-Vallverdu 2023 Redox Biol
  ...ant l-Ergothioneine prevents cystine lithiasis in the Slc7a9^-/- mouse model of cystinuria. https://doi.org/10.1016/j.redox.2023.102801 ...ine administration prevented cystine lithiasis in the Slc7a9^-/- mouse model by increasing urinary cystine solubility and recovered renal GSH meta
  3 KB (415 words) - 13:53, 18 July 2023
• Antico 2021 Sci Adv
  ...49 PINK1 activation–dependent diGLY sites in 22 proteins conserved across mouse and human systems. We use reconstitution assays to demonstrate direct ubiqu |organism=Mouse
  2 KB (271 words) - 17:45, 22 November 2021
• Lindenberg 2013 Abstract MiP2013
  ...s in mitochondrial proteome of brain and skeletal muscle in two transgenic mouse models for Huntington´s disease. Mitochondr Physiol Network 18.08. ...muscle from two different mouse models for HD (R6/2 mice and HdhQ-knock in mouse) were isolated and the mitochondrial proteomes of the HD mice and respectiv
  4 KB (544 words) - 15:14, 20 October 2017
• Hals 2017 Physiol Rep
  ...nd results indicate inhibitory effects on insulin secretion ''in vivo'' in mouse neonates. Negative effects may be lessened by the demonstrated swift and pr |organism=Human, Mouse
  3 KB (380 words) - 14:41, 27 March 2018
• Kemp 1994 BTK-226
  ...ical study of the producion of lactate by glutaminolysis and glycolysis in mouse macrophage hybridoma cells. In: ''What is Controlling Life?'' (Gnaiger E, G |organism=Mouse
  1 KB (173 words) - 19:14, 17 December 2023
• Gottlieb 2015 Fatty Acid Oxidation O2k-Network Discussion Forum
  |organism=Mouse
  452 bytes (61 words) - 11:06, 8 November 2016
• Fernando 2023 Commun Biol
  ...mitochondrial metabolism is a driver for fast skeletal muscle loss during mouse aging. https://doi.org/10.1038/s42003-023-05595-3 ...onsistent is the altered mitochondrial morphology. We further compared our mouse EDL aging signature with human data from the GTEx database, reinforcing the
  2 KB (278 words) - 16:16, 12 December 2023
• De la Rosa Vargas 2019 Arch Cardiovasc Dis
  ...rdiomyocytes due to the deletion of the mitochondrial protease YME1L. This mouse model recapitulates all the clinical features of DCM as well as the metabol Using our DCM mouse model, we will test whether reducing cardiac glucose overload to the heart
  2 KB (362 words) - 17:25, 26 March 2019
• Harisseh 2017 Basic Res Cardiol
  ...cardioprotective effect when administrated for postconditioning in C57BL6 mouse IR model. Treatment with AZP-531 rescued the myocardium from cell death at |organism=Mouse
  2 KB (325 words) - 10:11, 22 November 2017
• Liepinsh 2024 Br J Pharmacol
  ...y acids to prevent lethal accumulation of long-chain acylcarnitines in the mouse liver. Br J Pharmacol [Epub ahead of print]. https://doi.org/10.1111/bph.16 ...se effects remain unclear. We used a tamoxifen-induced Hmgcr-knockout (KO) mouse model, a multi-omics approach and mitochondrial function assessments to inv
  3 KB (380 words) - 15:47, 15 May 2024
• Hernandez-Vivanco 2012 J Pharmacol Exp Ther
  ...ls, which express very different percentages of VDCC types with respect to mouse chromaffin cells. These results demonstrate that the inhibitory action of p |organism=Human, Mouse, Bovines
  3 KB (365 words) - 16:29, 10 October 2016
• Herbst 2014 Abstract MiP2014
  ...ation to investigating regional variation in mitochondrial function in the mouse brain with both acute and chronic perturbations and compared our results wi ...for analysis of mitochondrial respiration in multiple regions in a single mouse brain.
  2 KB (327 words) - 15:22, 20 October 2017
• Roden 2015 Fatty Acid Oxidation O2k-Network Discussion Forum
  |organism=Human, Mouse
  483 bytes (60 words) - 10:27, 27 March 2018
• Chinas 2022 Metabolites
  ...tal high-fat and high-sucrose diet on cardiometabolic health in adult male mouse offspring. https://doi.org/10.3390/metabo12060563 ...ning can attenuate the deleterious effects of long-term HFHS in adult male mouse offspring.
  2 KB (352 words) - 09:56, 15 February 2024
• Gizatullina 2005 Biochim Biophys Acta
  ...FN (2005) Effects of extramitochondrial ADP on permeability transition of mouse liver mitochondria. Biochim Biophys Acta 1706:98-104. ...e opening of permeability transition pore (PTP). Following pretreatment of mouse liver mitochondria with 5 μM CAT and 75 μM Ca²⁺, the activity
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• Davoudi 2016 PLOS ONE
  ...e-complex III modify respiratory chain supercomplex formation in different mouse strains with a Bcs1l mutation. PLOS ONE 11:e0168774. ...hown to impede respirasome formation, a major concern for the use of C57BL mouse strains in mitochondrial research. In contradiction, another recent study s
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• Brandt 2013 Abstract MiP2013
  ...Stewart JB, Larsson NG, Kühlbrandt W (2013) Structure and function of aged mouse mitochondria. Mitochondr Physiol Network 18.08. ...igated the morphology and function of aged mammalian mitochondria. We used mouse models that would reveal changes in mitochondrial structure and function in
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• Dogan 2018 Cell Metab
  ...skeletal muscle-specific COX15 knockout (KO) mouse with an AOX-transgenic mouse. Surprisingly, the double KO-AOX mutants had decreased lifespan and a subst |organism=Mouse
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• Ivannikov 2013 J Mol Neurosci
  ...memory. In this study, we show by visualizing synaptic vesicle release in mouse hippocampal synaptosomes that presynaptic mitochondria and, specifically, t |organism=Mouse
  2 KB (203 words) - 15:39, 27 April 2015
• Takahashi 2016 Exp Gerontol
  ...glutamate transporter 1 (VGluT1) decreased compared with that in the young mouse brain. The administration of exogenous water-soluble CoQ₁₀ to ag |organism=Mouse
  2 KB (281 words) - 17:37, 25 February 2020
• Tichanek 2020 Sci Rep
  ...n and psychiatric-relevant behavioral deficits in spinocerebellar ataxia 1 mouse model. Sci Rep 10:5418. ...ntroversial. This study aimed to explore behavioral deficits in a knock-in mouse SCA1 (SCA1^154Q/2Q) model and to identify the underlying neuropat
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• Seok 2013 Proc Natl Acad Sci U S A
  ...LL, Herndon DN, Davis RW, Xiao W, Tompkins RG (2013) Genomic responses in mouse models poorly mimic human inflammatory diseases. Proc Natl Acad Sci U S A 1 ...earch to focus on the more complex human conditions rather than relying on mouse models to study human inflammatory diseases.
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• Claude 1940 Science
  |organism=Mouse
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• Aon 2015 J Gen Physiol
  ...a percentage of the total O₂ consumption flux was 11%/2.3% for mouse in states 4 and 3 followed by 2%/0.25% and 0.74%/0.29% in the rat and guine |organism=Mouse, Rat, Guinea pig
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• Pinkert 2013 Abstract MiP2013
  ...1-5]. We have developed or are currently characterizing transmitochondrial mouse models of human disease including models for Parkinson’s disease and Comp |organism=Mouse
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• Ferreira 2017 MITOEAGLE Obergurgl
  ...x|Ferreira Luciana]] Doxorubicin toxicity and mitochondrial dysfunction in mouse induced pluripotent stem cells-derived cardiomyocytes. In this work we used cultured mouse induced pluripotent stem cells (iPSC)-derived cardiomyocytes treated with 0
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• Konjar 2010 Immunology
  ...T, Peters C, Turk V, Turk B, Trapani JA, Kopitar-Jerala N (2010) Human and mouse perforin are processed in part through cleavage by the lysosomal cysteine p ..., we show that incubation of human NK cells and primary antigen-restricted mouse CTLs with the cathepsin L (CatL) inhibitor L1 resulted in a marked inhibiti
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• Boerma 2015 Radiat Res
  ...cts of local heart irradiation in a glutathione S-transferase alpha 4-null mouse model. Radiat Res 183:610-9. ...Nrf2 in the heart. Here we examined the sensitivity of this ''Gsta4''-null mouse model towards cardiac function and structure loss due to local heart irradi
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• Civiletto 2018 EMBO Mol Med
  ...ed cytochrome c oxidase (COX) activity of a muscle-specific Cox15 knockout mouse (Cox15^sm/sm). Rapamycin treatment restored autophagic flux, whic |organism=Mouse
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• Wagenaars J
  |topics=mouse model, skeletal muscle, complex 1, mPTP
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• Bratic 2013 J Clin Invest
  ...tion levels contribute to progeroid phenotypes came from the mtDNA mutator mouse. Recent evidence suggests that increases in aging-associated mtDNA mutation |organism=Human, Mouse, Other mammals, Drosophila, Caenorhabditis elegans
  2 KB (216 words) - 18:50, 9 October 2023
• Formiga-Jr 2022 J Vis Exp
  ...ions, inherited disorders, and tumors. Assessing mitochondrial function in mouse peripheral nerves can be challenging due to the small sample size, a limite |organism=Mouse
  2 KB (219 words) - 13:37, 2 November 2022
• Nilsson 2010 Thesis
  ...sson I (2010) Hypothalmic regulation of food intake – focus on the anx/anx mouse. Thesis Karolinska Institute Stockholm, Department of Molecular Medicine an |organism=Mouse
  5 KB (722 words) - 16:54, 17 March 2015
• Gutierrez 2022 Cell Rep Med
  ...the GLP1-IL-6 axis. We show that liraglutide transiently increases IL-6 in mouse circulation and IL-6R signaling in AT. Metronomic liraglutide treatment res |organism=Mouse
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• Votion 2015 Fatty Acid Oxidation O2k-Network Discussion Forum
  |organism=Mouse
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• Aguirre 2012 Mitochondrion
  ...-inducible NOS protein other than iNOS and modulates oxygen consumption in mouse skeletal muscle. |organism=Mouse
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• Garedew 2006 Biochim Biophys Acta
  ...excess capacity of cytochrome ''c'' oxidase in permeabilized fibers of the mouse heart. Biochim Biophys Acta, EBEC Short Reports Suppl 14 (2006):167-8. ...rtant baseline for further investigations of mitochondrial function in the mouse heart, including genetic models of acquired and inherited mitochondrial def
  3 KB (510 words) - 18:14, 10 January 2022
• Rogers 2011 PLoS One
  .... We describe optimization and validation of this technique using isolated mouse liver and rat heart mitochondria, and apply the approach to discover that i |organism=Mouse
  2 KB (344 words) - 10:48, 26 February 2015
• Huang 2017 Sci Rep
  ...against doxorubicin cardiotoxicity via improving mitochondrial function in mouse hearts. Sci Rep 7:11989. ...cardiomyocytes (H9c2). Honokiol upregulated the expression of PPARγ in the mouse heart. Honokiol repressed cardiac inflammatory responses and oxidative stre
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• Ferreira 2021 Redox Biol
  ...sed mitochondrial activity upon CatSper channel activation is required for mouse sperm capacitation. https://doi.org/10.1016/j.redox.2021.102176 .... To test this hypothesis, we used high-resolution respirometry to measure mouse sperm mitochondrial activity. We also measured mitochondrial membrane poten
  3 KB (340 words) - 19:21, 24 February 2023
• Schoeckel 2015 Cancer Metab
  ...s augmented the anti-tumor effect of BAY 87-2243 in a BRAF mutant melanoma mouse xenograft model. |organism=Human, Mouse
  3 KB (381 words) - 15:07, 9 November 2016
• Marks - DatLab
  ...reduced or the entire mark deleted by holding Shift and pressing the right mouse button, while moving the cursor along the ''x''-axis over the marked sectio ...tting a mark on a plot, the Scaling window may appear. This happens if the mouse cursor is set on the time axis.
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• Silva 2012 PLOS ONE
  ..., Da Poian AT, El-Bacha T (2012) Mitochondrial bioenergetic alterations in mouse neuroblastoma cells infected with Sindbis virus: implications to viral repl ...the effects of Sindbis virus infection on mitochondrial bioenergetics of a mouse neuroblastoma cell lineage, Neuro 2a. The modulation of mitochondrial funct
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• Yardeni 2021 Proc Natl Acad Sci U S A
  ...y AJ, Schaefer PM, McManus MJ, Marsh ED, Wallace DC (2021) An mtDNA mutant mouse demonstrates that mitochondrial deficiency can result in autism endophenoty ...a mouse strain harboring an mtDNA ND6 gene missense mutation (P25L). This mouse manifests impaired social interactions, increased repetitive behaviors and
  3 KB (391 words) - 10:46, 28 October 2022
• Eckert 2013 Neurochem Int
  ...vents mitochondrial dysfunction in the brain of the senescence-accelerated mouse-prone 8. Neurochem Int 62:595-602. ...one 8 (SAMP8) strain and its normally aging control senescence-accelerated mouse-resistant 1 (SAMR1) as a model for the age-dependent changes in mitochondri
  3 KB (383 words) - 07:51, 21 February 2020
• Sucha 2023 Int J Mol Sci
  ...J, Kuncova J, Cendelin J (2023) Experimental treatment with edaravone in a mouse model of spinocerebellar ataxia 1. https://doi.org/10.3390/ijms241310689 ...p, exploring the potential of edaravone to slow down SCA1 progression in a mouse knock-in SCA1 model. SCA1154Q/2Q and healthy SCA12Q/2Q mice were administer
  2 KB (317 words) - 15:47, 2 August 2023
• Bresciani Martins de Andrade P 2013 J Bioenerg Biomembr
  ...t oxygen consumption as a peripheral blood marker of brain energetics in a mouse model of severe neurotoxicity. J Bioenerg Biomembr 45:449-57. ...let oxygen consumption as a peripheral blood marker of brain function in a mouse model MeHg-induced neurotoxicity.
  3 KB (373 words) - 17:13, 27 March 2018
• Kluckova 2015 Methods Mol Biol
  ...ation , Cultured cells , Tumors , Mitochondria-targeted anticancer agents, Mouse mesothelioma tumor cells AE 17 cells |organism=Mouse
  2 KB (216 words) - 14:56, 13 November 2017
• Pesta 2014 Abstract MiP 2014
  |title=Dysregulation of muscle ATP synthesis in hypophosphatemic mouse models and in a patient with hypophosphatemia due to a mutation in NaPi2c. ...th P_i-ATP flux (''J''_ATP) in skeletal muscle in both mouse models of hypophosphatemia. Low plasma P_i levels in these animal
  4 KB (537 words) - 12:44, 21 March 2019
• Aidt 2013 PLoS Curr
  ...al respiration in the striatum of the Huntington's disease transgenic R6/2 mouse model. PLoS Curr 5. pii:ecurrents.hd.d8917b4862929772c5a2f2a34ef1c201. ...ion in Complex II and Complex IV flux control ratios was found in the R6/2 mouse striatum at 12 weeks of age compared to controls, confirming previous findi
  2 KB (312 words) - 21:21, 17 March 2019
• Fieni 2012 Nat Commun
  ...chondrial membrane, we compare mitochondrial calcium uniporter activity in mouse heart, skeletal muscle, liver, kidney and brown fat. Surprisingly, heart mi |organism=Mouse, Drosophila
  2 KB (253 words) - 14:58, 24 February 2020
• Wiedemann 1998 FEBS Lett
  ...l coefficients were detected only at oxygen concentrations close to the KM value of cytochrome c oxidase, with saponin-permeabilized fibers a significant in |organism=Mouse
  2 KB (239 words) - 14:57, 1 December 2015
• Yamaguchi 2007 Cell Death Differ
  ...the cytoplasm. This process can be studied in vitro with freshly isolated mouse liver mitochondria. Unfortunately, mitochondria frozen/thawed in standard s |organism=Mouse
  2 KB (227 words) - 17:03, 19 October 2017
• Gaglianone 2019 Sci Rep
  ...imals, a critical age where muscle regeneration is observed in the ''mdx'' mouse. Using substrates of complex I and complex II from the electron transport c |organism=Mouse
  2 KB (328 words) - 12:10, 25 July 2019
• Baelde 2023 Abstract IOC160
  ...Velden J, Ottenheijm C, de Winter J (2023) Kbtbd13^R408C-knockin mouse model elucidates mitochondrial pathomechanism in NEM6. Mitochondr Physiol N ...disease pathology. Therefore, we used the Kbtbd13^R408C-knockin mouse model that phenocopies NEM6 hallmarks, e.g muscle weakness, impaired muscle
  3 KB (501 words) - 14:24, 24 May 2023
• McLaughlin 2018 Biochem Biophys Res Commun
  ...) Bioenergetic consequences of compromised mitochondrial DNA repair in the mouse heart. Biochem Biophys Res Commun 504:742-48. ...int to the cause of respiratory flux limitations observed in mtDNA mutator mouse mitochondria being due to impairments within the energy transduction step c
  2 KB (319 words) - 11:29, 14 January 2019
• Hawley 2016 Diabetes
  ...at the AMPK sites. Oral administration of canagliflozin activated AMPK in mouse liver, although not in muscle, adipose tissue, or spleen. Because phosphory |keywords=Mouse primary hepatocytes, HEK 293 cells
  2 KB (311 words) - 15:52, 9 November 2016
• Wang 2015 Nat Commun
  ...rt, superoxide generation and as a membrane antioxidant. Here we present a mouse model in which UQ biosynthesis can be interrupted and partially restored at |organism=Mouse
  2 KB (230 words) - 16:56, 7 November 2016
• Gruenig 2017 Toxicol In Vitro
  ...of complex I and IV for entacapone was directly demonstrated in disrupted mouse liver mitochondria. In HepaRG cells, tolcapone-induced inhibition of mitoch |organism=Human, Mouse
  3 KB (332 words) - 11:25, 27 June 2019
• Glancy 2015 Nature
  ...nergy distribution, in the form of the proton-motive force, throughout the mouse skeletal muscle cell. Within this reticulum, we find proteins associated wi |organism=Mouse
  2 KB (222 words) - 15:19, 21 April 2016
• O´Gorman 1997 FEBS Lett
  ...act=Cyclosporin A sensitive swelling of mitochondria isolated from control mouse livers and from the livers of transgenic mice expressing human ubiquitous m |organism=Human, Mouse
  2 KB (220 words) - 15:37, 15 June 2015
• Takahashi 2013 Mech Ageing Dev
  ...on of coenzyme Q10 restores mitochondrial 3 oxygen consumption in the aged mouse brain. Mech Ageing Dev 134:580-6. |organism=Mouse
  2 KB (240 words) - 17:37, 25 February 2020
• Bellissimo 2023 Exp Physiol
  ...Sater AA, MacPherson REK, Perry CGR (2023) Memory impairment in the D2.mdx mouse model of Duchenne muscular dystrophy is prevented by the adiponectin recept ...is study? Can adiponectin receptor agonism improve recognition memory in a mouse model of Duchenne muscular dystrophy? What is the main finding and its impo
  2 KB (339 words) - 15:48, 19 December 2023
• Lemieux 2006 Biochim Biophys Acta
  ...l and capacity of mitochondrial respiration in permeabilized fibers of the mouse heart. Biochim Biophys Acta, EBEC Short Reports Suppl 14 (2006):201-2. ...ete. The present data provide an important baseline for further studies of mouse heart metabolism, including various genetic models of mitochondrial disease
  3 KB (453 words) - 18:14, 10 January 2022
• Harhous 2019 J Mol Cell Cardiol
  ...our results exclusively reveal a unique cellular distribution of STAT3 in mouse adult cardiomyocytes, along the T-tubules and in nucleus, under different c |organism=Mouse
  3 KB (425 words) - 12:20, 9 July 2019
• Garcia-Roves 2019 MiP2019
  |organism=Mouse
  646 bytes (81 words) - 15:18, 2 October 2019
• Friederich-Persson 2014 Adv Exp Med Biol
  ...ion but increases transport-independent oxygen consumption in immortalized mouse proximal tubular cells. Adv Exp Med Biol 812:157-63. ...umption (QO₂). We investigated the effect of Ang II on QO₂ in immortalized mouse proximal tubular cells over-expressing the NADPH oxidase subunit p22(phox);
  2 KB (349 words) - 10:40, 9 November 2016
• Chakrabarti 2018 MiP2018
  ...show that mitochondrial proteomes are distinctly different when comparing mouse with bat, and their mitochondrial lipid signatures clearly define the tissu |organism=Mouse, Other mammals, Caenorhabditis elegans
  5 KB (695 words) - 11:47, 20 August 2018
• Maekawa 2019 Biochem Biophys Rep
  ...chondrial respiration of complex II is not lower than that of complex I in mouse skeletal muscle. Biochem Biophys Rep 21:100717. ...complex II is essential for the normal functioning of complex I and II in mouse SKM mitochondria.
  3 KB (387 words) - 12:52, 25 February 2020
• Anderson 2019 Acta Neuropathol
  ...valent of a disease-associated human S59L mutation, S55L in the endogenous mouse gene. CHCHD10^S55L mice develop progressive motor deficits, myopa |organism=Mouse
  2 KB (317 words) - 11:32, 16 August 2019
• Leveen 2011 Hepatology
  ...on introduced into Bcs1l causes postnatal Complex III deficiency: a viable mouse model for mitochondrial hepatopathy. Hepatology 53:437-47. ...yonic lethality, and thus few disease models are available. We developed a mouse model for GRACILE syndrome, a neonatal mitochondrial disease with liver and
  2 KB (351 words) - 15:48, 19 March 2015
• Kawalec 2015 PLoS One
  ...A neuropathy (CMT2A). Here, cellular energy metabolism was investigated in mouse embryonic fibroblasts (MEF) differing in the presence of the Mfn2 gene; con |keywords=Mouse embryonic fibroblast
  2 KB (351 words) - 14:51, 13 November 2017
• Nakashima 2017 Free Radic Biol Med
  ...25 % of UVA in human keratinocyte mitochondria, compared to 68 % of UVA in mouse skin. Skin autofluorescence was reduced by blue light, suggesting flavins a |organism=Human, Mouse
  2 KB (240 words) - 17:56, 24 December 2021
• Baxter 2020 Elife
  ...mRNA transcripts with low 5'UTR GC content. BUD23 emerges as essential to mouse development, and to postnatal cardiac function. |keywords=Cell biology, Human, Mouse
  2 KB (309 words) - 13:19, 7 March 2020
• Girer 2019 Int J Mol Sci
  ...ational AHR deficiency. Utilizing a novel tamoxifen-inducible AHR knockout mouse model, we analyzed the effects of hepatocyte-targeted AHR loss in adult mic |organism=Mouse
  2 KB (322 words) - 16:21, 27 February 2019
• Segalés 2013 Am J Physiol Endocrinol Metab
  ...ial respiration in Mfn2-deficient muscle cells. The expression of ΔMfn2 in mouse liver or in hepatoma cells stimulated gluconeogenesis. In addition, ΔMfn2 |organism=Mouse
  2 KB (352 words) - 16:00, 13 November 2017
• Melin 2022 JHEP Rep
  ...M, Vozenin MC, Herrmann E, Candinas D, Aebersold DM, Stroka D (2022) A new mouse model of radiation-induced liver disease reveals mitochondrial dysfunction ...rosis of the pericentral sinusoids. In this study, we aimed to establish a mouse model of RILD to investigate the underlying mechanism of radiation-induced
  4 KB (476 words) - 14:35, 28 November 2022
• Johnston 2015 Abstract MiPschool London 2015
  ...proposed bottleneck mechanisms. Using approximate Bayesian computation and mouse data, we find most statistical support for a combination of binomial partit |organism=Mouse
  2 KB (231 words) - 15:39, 10 April 2015
• Percival 2013 Hum Mol Genet
  ...(2013) Defects in mitochondrial localization and ATP synthesis in the mdx mouse model of Duchenne muscular dystrophy are not alleviated by PDE5 inhibition. ...has remained poorly defined and unknown ''in vivo''. Here, we used the mdx mouse model of DMD and non-invasive spectroscopy to determine the impact of dystr
  3 KB (338 words) - 16:20, 25 November 2015
• George 2015 Abstract MiPschool Greenville 2015
  ...iratory oxygen flux (JO₂) was measured in saponin-permeabilized mouse brain cortex samples, prepared as previously described [2]. ...retation that lactate oxidation occurs outside the mitochondrial matrix in mouse cortex and rat hippocampus.
  3 KB (403 words) - 16:41, 7 November 2016
• Donnelly 2024 EU-METAHEART MC2 Meeting
  ...isolated mitochondria. Performing steady-state respirometry with isolated mouse cardiac mitochondria [2] we found that oxygen limitation of respiration red |organism=Mouse
  2 KB (328 words) - 15:53, 13 March 2024
• De Paula Nascimento-Castro 2022 Biomedicines
  ...l characterization of behavioral and hippocampal dysfunction in the YAC128 mouse model of Huntington's disease. https://doi.org/10.3390/biomedicines10061433 ...een in HD may be related to hippocampal dysfunction. We used the YAC128 HD mouse model to perform a temporal characterization of the behavioral and hippocam
  3 KB (337 words) - 13:48, 22 November 2022
• Gray 2017 Neuromethods
  ...hondria isolated from HEK293T cells, and (3) by mitochondria isolated from mouse liver, which are useful as a general model of mitochondrial function. |organism=Human, Mouse
  2 KB (240 words) - 13:34, 14 June 2017
• Fetterman 2013 Biochem J
  exchange) mouse, in which the mtDNA from the C3H/HeN mouse has been inserted on to the C57/BL6 nuclear background
  2 KB (343 words) - 16:31, 7 November 2016
• Kim 2023 Nat Commun
  ...s through p-AMPK enhancement, thus protecting kidney function in our ADTKD mouse model. Conversely, genetic ablation of MANF in the mutant thick ascending l |organism=Mouse
  2 KB (314 words) - 11:25, 26 April 2024
• Sadhukhan 2016 Proc Natl Acad Sci U S A
  ...ation has prompted us to examine protein lysine succinylation in different mouse tissues in the presence and absence of SIRT5. Protein lysine succinylation |organism=Mouse
  2 KB (347 words) - 10:03, 8 November 2016
• Sobotka 2017 Thesis
  ...romopyruvate caused morphological and functional damage of primary rat and mouse hepatocytes in cell cultures; this toxic effect was accompanied by an incre |organism=Mouse, Rat
  3 KB (369 words) - 17:57, 22 November 2017
• Giordano 2021 Gene Ther
  ...bryonic fibroblasts (iMEFs), human lung carcinoma cells (A549) and primary mouse pulmonary arterial smooth muscle cells (PASMCs). AOX protein was detectable |organism=Mouse
  2 KB (330 words) - 19:10, 15 March 2023
• Sendon 2019 Abstract IOC139
  ...M, Simard ML, Stewart J (2019) Development and characterization of a novel mouse model carrying specific mitochondrial DNA mutations. Mitochondr Physiol Net ...on between WT and mutant mice to further molecularly characterize this new mouse model.
  3 KB (385 words) - 10:51, 3 June 2019
• Liu 2020 Cell Death Dis
  ...imens from patients with carotid occlusive diseases. Likewise, the ligated mouse arteries exhibited an enhanced mitochondrial binding of DNMT1, repressed mi |organism=Mouse
  2 KB (323 words) - 16:35, 29 February 2020
• Pochakom 2022 Brain Sci
  ...c treatment positively modulates the microbiota-gut-brain axis in the BTBR mouse model of autism. https://doi.org/10.3390/brainsci12060781 ...strains in mitigating autism-related symptomology in the BTBR T+ Itpr3tf/J mouse model of autism spectrum disorder (ASD). Male juvenile BTBR mice were rando
  2 KB (320 words) - 14:41, 22 November 2022
• Collard 2018 Mol Cell Biol
  ...levels: into isolated mitochondria, in patient fibroblast cells, and in a mouse model. Results from Western blots and enzyme activity assays confirmed the |organism=Mouse
  2 KB (247 words) - 11:04, 13 March 2018
• Schoenenberger 2016 Cancer Res
  ...glycolysis, decreased oxygen consumption, and decreased ATP production in mouse embryonic fibroblasts, providing insights into the cellular changes potenti |organism=Mouse
  2 KB (358 words) - 12:03, 28 March 2018
• Bellissimo 2023 BEC
  ...hexokinase clamp was included. CRC was similar in wildtype and D2.''mdx'' mouse cardiac left ventricle fibers whether assessed with ADP and creatine (adeny |organism=Mouse
  4 KB (491 words) - 15:35, 31 July 2023
• Zanou 2021 Nat Commun
  ..., and decreases pyruvate dehydrogenase phosphorylation in human muscle and mouse myotubes. Countering Ca²⁺ leak or preventing mitochondrial Ca<su |organism=Mouse
  2 KB (334 words) - 10:16, 24 March 2022
• Kovalcikova 2015 Abstract MiPschool London 2015
  |title=TMEM70 ablation leads to embryonic lethality in mouse knockout due to impairment of ATP synthase. ...role of TMEM70 in experimental animals shows that Tmem70 deficiency in the mouse has lethal consequences that are analogous to TMEM70 dysfunction in humans.
  3 KB (356 words) - 16:34, 10 April 2015
• Flis 2019 Int J Mol Sci
  ...l muscle energy metabolism and ameliorates reduction in grip strength in a mouse model of amyotrophic lateral sclerosis. Int J Mol Sci 20:E233. |organism=Mouse
  2 KB (350 words) - 10:20, 8 August 2019
• Dhandapani 2014 Abstract IOC 2014-04 Schroecken
  ...ive therapy approach for mitochondrial based HF, for which, we generated a mouse model expressing transgenic AOX. ...r alleviate the symptoms. We will challenge cardiac functions in different mouse models of cardiomyopathy by spatio-temporal manipulation of specific gene e
  3 KB (464 words) - 09:19, 14 June 2017
• Balmaceda 2024 Biochim Biophys Acta Mol Basis Dis
  ...y ETS impairment in a tissue-specific manner using pathologically relevant mouse models lacking either Ndufs4 or Ttc19, leading to Complex I (CI) or Complex |organism=Mouse
  2 KB (345 words) - 09:44, 28 February 2024
• Koene 2011 J Inherit Metab Dis
  |title=Koene S, Willems PH, Roestenberg P, Koopman WJ, Smeitink JA (2011) Mouse models for nuclear DNA-encoded mitochondrial complex I deficiency. J Inheri ...erapeutic potential in suitable animal models. Here, we discuss two recent mouse models for nDNA-encoded complex I deficiency and their tissue-specific knoc
  2 KB (252 words) - 13:27, 14 October 2023
• Mills 2016 Cell Metab
  ...enhance NAD⁺ biosynthesis and ameliorate various pathologies in mouse disease models. In this study, we conducted a 12-month-long NMN administrat |organism=Mouse
  2 KB (247 words) - 11:31, 10 July 2018
• Kiebish 2013 J Lipid Res
  ...ome, we interrogated the cardiac structural and signaling lipidome of this mouse model as well as its myocardial bioenergetic phenotype. A decrease in the d |organism=Mouse
  3 KB (349 words) - 17:51, 7 November 2016
• Li 2013 Free Radic Biol Med
  ...sis of cells bearing mitochondria derived from young, middle-aged, and old mouse skeletal muscles and synaptosomes. Significant age-associated alterations i |organism=Mouse
  2 KB (253 words) - 18:51, 29 February 2020
• Ponce 2019 Thesis
  ...ons with Cdk1. Using cardiac specific cyclin C knockout and overexpression mouse models, we determined cyclin C regulates mitochondria morphology under basa |organism=Mouse
  2 KB (264 words) - 18:08, 19 May 2020
• Lopez Sanchez 2020 PLoS One
  ...ieved with other research models. Furthermore, we used a xenomitochondrial mouse model generated in our laboratory that harbors wild-type, C57BL/6J ''Mus mu
  3 KB (370 words) - 23:00, 16 October 2020
• Karlsson 2016 Shock
  ...(2016) Diverse and tissue-specific mitochondrial respiratory response in a mouse model of sepsis-induced multiple organ failure. Shock 45:404-10. ...luate the temporal dynamics of brain and liver mitochondrial function in a mouse model of sepsis. Sepsis was induced by cecal ligation and puncture. Control
  2 KB (351 words) - 13:40, 7 March 2020
• Visavadiya 2020 Mol Cell Biochem
  ...health, due to impaired mitochondrial function and remodeling. Exposure of mouse hepatocytes to tumor conditioned media models aspects of cachexic liver mit |organism=Mouse
  3 KB (360 words) - 17:21, 22 February 2022
• Sobotka 2016 J Bioenerg Biomembr
  ...ndrial functions contribute to 3-bromopyruvate toxicity in primary rat and mouse hepatocytes. J Bioenerg Biomembr 48:363-73. ...3-BP (p < 0.001). This toxic effect of 3-BP was also proved using primary mouse hepatocytes. In isolated mitochondria, 3-BP induced a dose- and time-depend
  2 KB (328 words) - 10:17, 8 November 2016
• Gomez 2022 Nutrients
  ...to mitochondrial membrane fatty acid remodeling and reduced efficiency in mouse liver mitochondria. https://doi.org/10.3390/nu14030559 ...s imply that endogenous DHA production is vital for the normal function of mouse liver mitochondria and could be relevant not only for mice but also for hum
  3 KB (344 words) - 13:27, 5 December 2022
• Guillet 2011 FASEB J
  ...er P (2011) Bioenergetic defect associated with mKATP channel opening in a mouse model carrying a mitofusin 2 mutation. FASEB J 25:1618-27. ...ther mitochondrial dysfunction is a feature of CMT2A, we used a transgenic mouse model expressing in neurons a mutated R94Q form of human MFN2 shown to indu
  2 KB (354 words) - 14:26, 13 November 2017
• Gispert 2009 PLoS One
  ...increased aggregation of mitochondria only under stress in PINK1-deficient mouse neurons. |keywords=Parkinson, Mitochondrial protein kinase PINK1, PINK1-deficient mouse neurons, Aging
  3 KB (418 words) - 13:50, 7 May 2019
• Kacso 2016 Biochem J
  ...nár MJ, Nagy Z, Patocs A, Adam-Vizi V, Chinopoulos C (2016) Two transgenic mouse models for β-subunit components of succinate-CoA ligase yielding pleiotrop ...ts as well as the availability of the transgenic mouse colonies will be of value in understanding SUCL deficiency.
  3 KB (425 words) - 11:54, 8 November 2016
• Takahashi 2014 Exp Gerontol
  ...ich were rescued from embryonic lethality via the transgenic expression of mouse clk-1. Tg96/I mice lived longer and had smaller bodies than wild-type mice, |organism=Mouse
  2 KB (254 words) - 17:37, 25 February 2020
• Derungs 2017 Mol Psychiatry
  ...ognitive deficits and improves mitochondrial function in an APP transgenic mouse model of Alzheimer's disease. Mol Psychiatry 22:605-14. ...deletion in the PSAPP transgenic mice, an established Alzheimer's disease mouse model of β-amyloidosis. p66^Shc-ablated PSAPP mice were characte
  2 KB (367 words) - 10:59, 25 June 2019
• Quispe 2018 Redox Biol
  ...as to investigate the potential protective effect of (PhSe)₂ on mouse hippocampal cell line (HT22) exposed to tert-BuOOH (''in vitro'' model of o |keywords=Antioxidant, Diphenyl diselenide, Glutathione peroxidase, Mouse Hippocampal Neuronal HT22 cells, Mitochondrial dysfunction, Oxidative stres
  3 KB (353 words) - 09:06, 5 May 2020
• Laner 2013 ASMRM
  ...rt|H₂O₂ production measured with Amplex® Ultrared in mouse heart mitochondria]] was not only a function of respiratory substrate and c |organism=Mouse
  3 KB (367 words) - 18:27, 10 January 2022
• Lieder 2022 J Cardiovasc Pharmacol Ther
  ...RIC (15% ± 5% vs 6% ± 3% before). For comparison, infarct size in isolated mouse hearts after global ischemia and reperfusion was 22% ± 14% of left ventric |organism=Mouse
  3 KB (352 words) - 15:31, 28 November 2022
• Munro 2019 Aging Cell
  ...</sub>O₂; as a proxy of overall ROS metabolism) between NMR and mouse skeletal muscle and heart. We found that the two species had comparable rat |organism=Mouse, Other mammals
  3 KB (369 words) - 13:23, 7 March 2020
• Calvo 2017 Mol Cell Proteomics
  ...JA, Mootha VK (2017) Comparative analysis of mitochondrial N-termini from mouse, human, and yeast. Mol Cell Proteomics 16:512-23.
  453 bytes (64 words) - 21:21, 16 January 2021
• Aral 2018 MiP2018
  ...ology Society|Aral Cenk]] Effects of melatonin treatment on LETM1 silenced mouse embryonic fibroblast cells. ...n oxidative stress and melatonin on mitochondrial function in immortalized mouse embryonic fibroblast cells, to suppress the LETM1 gene siRNA transfection,
  3 KB (399 words) - 09:15, 20 August 2018
• Kluza 2011 PLoS One
  ...n vivo treatment with the pro-oxidants, PEITC and Trisenox, in a syngeneic mouse tumor model. Conversely, inhibition of glycolysis caused derepression of re |keywords=Leukemia cell line, syngeneic mouse tumor model, chronic myeloid leukemia (CML) patients, imatinib, HIF-1α, NA
  3 KB (356 words) - 18:22, 31 January 2020
• Minuzzi 2019 MiPschool Coimbra
  ...Physiology Society|MiPsociety]] A pilot study on mitochondrial function of mouse skin using high-resolution respirometry. ...showed a higher Complex I- and Complex II-linked OXPHOS capacity than CTL mouse skin. The optimization of protocols showed robust and stable oxygen fluxes
  3 KB (464 words) - 10:55, 24 June 2019
• Youcef 2015 Biochem Pharmacol
  ...the cardioprotective effect of cyclosporin A in myocardial ischemia in the mouse. Biochem Pharmacol 94:22-9. ...resistant to CsA inhibition of mPTP opening. TK activity was documented in mouse heart and rat cardiomyoblasts mitochondria. By proximity ligation assay TK
  3 KB (388 words) - 16:44, 26 March 2018
• P/E control ratio
  = ''P/E'' from mouse to man = |title=Gnaiger E (2020) ''P/E'' from mouse to man. Mitochondr Physiol Network (2014-05-20) last update 2020-11-12.
  4 KB (623 words) - 01:14, 31 December 2020
• Carroll 2005 J Biol Chem
  |abstract=We present evidence that rat and mouse thymi contain mitochondrial uncoupling protein (UCP 1). Reverse transcripta |organism=Mouse, Rat
  2 KB (260 words) - 16:07, 23 February 2015
• Cecatto 2023 MitoFit
  ...ation in brain mitochondria: Insights from high-resolution respirometry in mouse, rat and ''Drosophila'' brain, ischemia and aging models. MitoFit Preprints ...ation in brain mitochondria: Insights from high-resolution respirometry in mouse, rat and ''Drosophila'' brain, ischemia and aging models]<br/>
  4 KB (543 words) - 09:47, 23 November 2023
• Ikaga 2015 Biochem Biophys Rep
  ...the present study, we found that AQP8 was expressed in the mitochondria in mouse adipose tissues and 3T3-L1 preadipocytes, and investigated its role by supp |keywords=Aquaporin-8, Mitochondria, Adipocyte, Mouse 3T3-L1 preadipocytes
  3 KB (390 words) - 14:42, 13 November 2017
• Zhuang 2018 Thesis
  ...aims at investigating the expression and function of AOX in the transgenic mouse brain and exploring therapeutic potential of AOX in human diseases. AFG3l2 ...tigated the expression and function of AOX in the brain of this transgenic mouse model. And we established a lentivirus vector to apply AOX gene to human ce
  4 KB (549 words) - 15:22, 18 April 2018
• Bertero 2020 Circ Res
  |organism=Mouse
  736 bytes (86 words) - 16:17, 7 May 2020
• N/S pathway control ratio
  ....5 in mouse heart mitochondria. The S-pathway is highly dominant in human, mouse, and rat liver mitochondria, but not in trout liver mitochondria.
  2 KB (300 words) - 19:14, 30 December 2020
• McCommis 2020 bioRxiv
  ...also able to prevent further remodeling in an ischemic, pressure-overload mouse model of heart failure. In conclusion, loss of mitochondrial pyruvate utili
  2 KB (287 words) - 09:21, 4 September 2023
• Schweitzer 2019 FASEB J
  ...nded by lipodystrophy not phenocopied in people. Herein, 2 muscle-specific mouse models were studied: 1) Lpin1 exon 3 and 4 deletion, resulting in a hypomor |organism=Mouse
  2 KB (337 words) - 21:29, 17 February 2021
• Canto 2019 MiP2019
  ...nto Alvarez]] Mitochondrial dynamics and cellular metabolism: lessons from mouse models. ...etabolism, we have generated a collection of conditional, tissue-specific, mouse models for defective fusion and fission mechanisms. Further, we have examin
  3 KB (376 words) - 13:21, 1 October 2019
• Boardman 2020 Am J Physiol Heart Circ Physiol
  ...NT, Pedersen TM, Rossvoll L, Hafstad AD, Aasum E (2020) Diet-induced obese mouse hearts tolerate an acute high fatty acid exposure that also increases ische ...acute high FA-load. Diet-induced obese (DIO) and age-matched control (CON) mouse hearts were perfused in the presence of low or high FA-load (0.4 and 1.8 mM
  3 KB (360 words) - 18:25, 6 November 2020
• Hedges IBEC2012
  in C57BL/6J wild-type and myostatin-deficient mouse soleus and white |organism=Mouse
  2 KB (230 words) - 09:23, 24 May 2019
• Davila 2018 Elife
  |keywords=NAD, NADH, Cell biology, Mitochondria, Mononucleotide, Mouse, Niacin, Nicotinamide |organism=Mouse
  2 KB (261 words) - 18:04, 31 January 2022
• Bellissimo 2022 MitoFit
  ...and that its regulation by adenylates is specific to ATP in permeabilized mouse quadriceps fibres. Accelerating matrix ADP/ATP cycling with creatine had no |organism=Mouse
  3 KB (444 words) - 14:59, 20 February 2023
• Souza da Silva 2020 Mol Neurobiol
  ...sine neuroprotection of presynaptic mitochondrial calcium homeostasis in a mouse study with amyloid-β oligomers. Mol Neurobiol 57:4790-809. ...lead to deteriorated neural activity and cell death. In this study, an AD mouse model induced by ICV (intracerebroventricular) injection of AβOs was used
  3 KB (347 words) - 10:38, 16 April 2021
• Murray 2013 Exp Physiol
  ...clude that mouse skeletal muscle mitochondria and, in particular, those of mouse quadriceps closely resemble the mitochondria of human quadriceps (vastus la |organism=Human, Mouse
  8 KB (1,107 words) - 12:10, 27 March 2018
• Adams 2010 Biochim Biophys Acta
  ...presence of constitutively expressed mitochondrial uncoupling protein 1 in mouse thymocytes. In our endeavours to understand the role of mitochondrial uncou |organism=Mouse
  2 KB (269 words) - 11:22, 26 May 2015
• Van Doan 2023 Abstract IOC162
  |title=Van Doan K, Luongo TS, Mukherjee S, Baur JA (2023) Mouse cardiac mitochondria are resilient to Nampt-dependent NAD⁺ los. Mouse cardiomyocytes are able to adapt to low cellular NAD⁺ concentrat
  2 KB (292 words) - 17:40, 18 September 2023
• Giordano 2018 Am J Respir Cell Mol Biol
  ...ast, the early-phase inflammatory response induced by acute CS exposure of mouse lung, i.e. infiltration by macrophages and neutrophils and adverse signalin |organism=Mouse
  2 KB (362 words) - 10:12, 8 June 2020
• Damgaard 2022 iScience
  ...RW, Larsen S, Treebak JT (2022) Intravenous nicotinamide riboside elevates mouse skeletal muscle NAD⁺ without impacting respiratory capacity or i |organism=Mouse
  2 KB (278 words) - 14:22, 5 December 2022
• Englund 2022 Mol Metab
  ...nescent cells, and skeletal muscle dysfunction in mice and humans. Using a mouse model of p21 overexpression (p21OE), we examined if p21 mechanistically con |organism=Mouse
  2 KB (268 words) - 19:17, 24 February 2023
• Boutant 2016 Cell Rep
  ...on could be therapeutically used as a CR-mimetic strategy. Here, we used a mouse model of moderate SIRT1 overexpression to test whether SIRT1 gain of functi |organism=Mouse
  2 KB (269 words) - 17:00, 9 November 2017
• Lauritzen 2010 Mol Cell Biol
  ...d in such pathologies. In the present study we designed a mouse model that allows us to specifically induce mitochondrial DNA toxicity in the forebrain neuro |organism=Mouse
  2 KB (278 words) - 15:07, 13 November 2017
• Morato 2015 Cell Death Differ
  ...treatment or by the moderate transgenic overexpression of SIRT1 in a X-ALD mouse model. Both strategies normalized redox homeostasis, mitochondrial respirat |organism=Mouse
  2 KB (252 words) - 08:22, 21 February 2020
• Volani 2017 Metallomics
  ...wo genetically divergent mouse strains, namely C57BL/6N and FVB mice. Both mouse strains differed in their basal iron levels and their metabolic responses t |organism=Mouse
  3 KB (382 words) - 03:19, 23 November 2021
• Dumollard 2007 Development
  ...Ward Z, Carroll J, Duchen MR (2007) Regulation of redox metabolism in the mouse oocyte and embryo. Development 134:455-65. https://doi.org/10.1242/dev.0274 ...of intermediary substrates. It has been known for some time that the early mouse embryo metabolises external pyruvate and lactate but not glucose to produce
  2 KB (298 words) - 07:09, 11 October 2023
• SfRBM Annual Conference 2021 Virtual
  ...etween Hydrogen Peroxide Production and Coenzyme Q-redox State in Isolated Mouse Brain Mitochondria.''
  1 KB (118 words) - 10:55, 22 November 2021
• Herbst 2017 Appl Physiol Nutr Metab
  ...ain mitochondria, oxygen consumption was measured in saponin-permeabilized mouse brain cortex samples, and rat prefrontal cortex and hippocampus (dorsal) su |organism=Mouse, Rat
  2 KB (289 words) - 15:13, 11 October 2018
• Cecatto 2022 MitoFit CaG
  |organism=Mouse
  780 bytes (88 words) - 11:53, 12 February 2022
• Madeo 2020 US Patent
  |organism=Mouse
  895 bytes (119 words) - 14:45, 14 July 2021
• Robinson 2019 Am J Physiol Cell Physiol
  |abstract=Rat L6 and mouse C2C12 cell lines are commonly used to investigate myocellular metabolism. M ...Lipid oxidation, Muscle cells, Reactive oxygen species, Rat L6 myoblasts, Mouse C2C12 myoblasts
  3 KB (418 words) - 13:22, 7 March 2020
• Bahire 2023 Mitochondrion
  ...23) Hemispheric analysis of mitochondrial complex I and II activity in the mouse model of ischemia-reperfusion-induced injury. https://doi.org/10.1016/j.mit |organism=Mouse
  2 KB (281 words) - 13:06, 7 March 2023
• Zhang 2015 J Cell Physiol
  ...DK is a mitochondrial NADK that is enriched and nutritionally-regulated in mouse liver, and a MNADK-deficient patient exhibits symptoms characteristic of mi
  2 KB (288 words) - 10:43, 10 April 2022
• O2k-Publications: Fibroblast
  ...st cultured this cell line, obtained the cells from desegregated NIH Swiss mouse embryo fibroblasts. The cell line has since become a standard fibroblast ce
  2 KB (318 words) - 13:02, 11 January 2017
• Lopez-Erauskin 2013 Hum Mol Genet
  ..., we identified a marked oxidation of key OXPHOS system subunits in Abcd1- mouse spinal cords at presymptomatic stages. Altogether, our results illustrate s |organism=Mouse
  3 KB (378 words) - 14:05, 28 April 2015
• Doig 2019 bioRxiv
  ...nges in NAD+ levels but no overt change in metabolism compared to the H6KO mouse. |organism=Mouse
  3 KB (402 words) - 15:17, 12 March 2019
• Konieczny 2008 J Cell Biol
  ...nd function. Analysis of newly generated plectin isoform–specific knockout mouse models revealed that IF aggregates accumulate in distinct cytoplasmic compa |organism=Mouse
  2 KB (267 words) - 15:55, 20 March 2015
• Kim 2023 bioRxiv
  ...Conversely, genetic ablation of endogenous MANF upregulated in the mutant mouse and human tubular cells worsens autophagy suppression and kidney fibrosis. |organism=Mouse
  3 KB (363 words) - 15:31, 9 February 2023
• Pallag 2022 Int J Mol Sci
  ...b>-ATPase operation in the forward mode. This was observed in CI-inhibited mouse liver and kidney mitochondria that exhibited high levels of proline oxidati |organism=Mouse
  3 KB (409 words) - 15:12, 9 December 2022
• Lopez 2009 J Pineal Res
  ...atonin on normal mitochondrial functions. Mitochondria were recovered from mouse liver cells and incubated ''in vitro'' with melatonin at concentrations ran |organism=Mouse
  2 KB (287 words) - 08:06, 21 February 2020
• Dall 2019 J Biol Chem
  ...t'' knockout has only minor consequences for mitochondrial function in the mouse liver. |organism=Mouse
  3 KB (417 words) - 15:31, 15 October 2019
• Rawat 2019 J Mol Biol
  ...n, Protein misfolding, Protein turnover, Proteomics, Proteostasis, Neuro2a mouse neuroblastoma cells |organism=Mouse
  2 KB (278 words) - 11:11, 14 August 2019
• Cacabelos 2016 Acta Neuropathol Commun
  ...es in spinal cord mitochondrial function and oxidative stress markers in a mouse model of ALS. Acta Neuropathol Commun 4:3. ...y, Fatty acid composition, Oxidative damage, Estrogens, Tissue slice, N2A mouse neuroblastoma cell
  3 KB (393 words) - 17:07, 9 November 2017
• Jiang 2013 Nature
  ...arboxylic-acid-cycle-associated [[malic enzyme]]s ME1 and ME2 in human and mouse cells. Both malic enzymes are important for NADPH production, lipogenesis a |organism=Human, Mouse
  2 KB (297 words) - 11:11, 28 April 2015
• McLaughlin 2020 Sci Rep
  |abstract=The mitochondrial mutator mouse is a well-established model of premature aging. In addition to accelerated |organism=Mouse
  2 KB (292 words) - 10:11, 4 March 2020
• Vigueira 2014 Cell Rep
  ...MPC2 deficiency resulted in embryonic lethality in mice. However, a second mouse line expressing an N-terminal truncated MPC2 protein (Mpc2Δ16) was viable |organism=Mouse
  2 KB (258 words) - 14:20, 18 March 2018
• Wijermars 2016 Am J Transplant
  ...and brain), a remaining question is to what extend these observations for mouse translate to man. We here show that succinate accumulation is not a univers |organism=Human, Pig, Mouse, Rat
  2 KB (273 words) - 13:11, 4 July 2022
• Larsen 2021 Cell Mol Gastroenterol Hepatol
  ...ize the lipid and fatty liver phenotype in human plasma, cell models and a mouse model. ...nt phenotype, but no clear plasma lipid abnormalities were observed in the mouse model. In the siTMEM199 and siCCDC115 HepG2 hepatocyte models, increased nu
  3 KB (473 words) - 17:17, 22 February 2022
• Kopitar-Jerala 2015 Front Cell Neurosci
  ...o-inflammatory M1 and anti-inflammatory M2 microglia in stefin B-deficient mouse brain compared with control mice. In our recent work, we demonstrated that |organism=Mouse
  2 KB (286 words) - 13:40, 27 July 2016
• Ferreira 2020 PLoS Genet
  ...n. To evaluate the effects of infection on mitochondrial disease we used a mouse model of Leigh Syndrome, where a missense mutation in the Taco1 gene result |organism=Mouse
  2 KB (278 words) - 17:20, 11 March 2020
• Burtscher J 2016 Abstract MitoFit Science Camp 2016
  |title=Oxidative phosphorylation in the healthy and epileptic mouse brain. ...rent brain tissues implicated in neurodegenerative diseases of the healthy mouse and disease models, while leaving enough material for further studies on th
  3 KB (364 words) - 18:45, 10 January 2022
• García-Corzo 2015 Biochim Biophys Acta
  ...hich may be improved by using different pharmacological formulations. In a mouse model (Coq9(X/X)) of mitochondrial encephalopathy due to CoQ deficiency, we |keywords=Ubiquinol-10; CoQ10 deficiency; Mitochondrial encephalopathy; Mouse model
  2 KB (291 words) - 12:37, 3 April 2021
• Brennan 2006 Biochim Biophys Acta
  ...ated with brown adipose tissue but has recently been discovered in rat and mouse thymus. We wished to establish whether there was a thermogenic role for UCP |organism=Mouse, Rat
  2 KB (284 words) - 14:57, 24 March 2015
• Porter 2016 Cell Metab
  ..., Rasmussen BB, Borsheim E, Toliver-Kinsky T, Sidossis LS (2016) Human and mouse brown adipose tissue mitochondria have comparable UCP1 function. Cell Metab |organism=Human, Mouse
  2 KB (278 words) - 12:58, 30 November 2018
• Wojtala 2014 Abstract MiP2014
  ...deficiency on p66Shc-Ser36 phosphorylation pathway in NDUFS4^-/- mouse tissues. ...spectrometry analysis was also performed for selected NDUFS4^-/- mouse tissues.
  3 KB (474 words) - 09:00, 18 March 2020
• Cannon 2015 Fatty Acid Oxidation O2k-Network Discussion Forum
  |organism=Human, Mouse
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• Selwood 2017 US Patent
  |organism=Mouse
  820 bytes (104 words) - 14:09, 14 July 2021
• Zeidler 2017 J Biol Chem
  ...decreased the Crabtree effect in Huh7 and C2C12 cells and abrogated it in mouse neuroblastoma N2A cells. Interestingly, the fact that the Crabtree effect w |organism=Mouse
  3 KB (401 words) - 16:35, 5 September 2022
• Cahill 2015 J Biol Chem
  ...disassembly by guanine nucleotides and high ionic strength solutions. In a mouse embryonic fibroblast (MEF) model, Drp1 C452F cells exhibited abnormal mitoc |organism=Mouse
  3 KB (382 words) - 17:08, 9 November 2017
• Kiss 2014 FASEB J
  ...iting no diaphorase activity we show that mitochondrial diaphorases in the mouse liver contributed up to 81 % to the NAD⁺ pool during respiratory |organism=Mouse
  2 KB (278 words) - 13:35, 2 August 2023
• Echevarría 2014 Biochem J
  ...f Gln-tRNAGln ''in vitro''. Here we demonstrate that mgatA interference in mouse cells produces a strong defect in mitochondrial translation without affecti |organism=Human, Mouse
  2 KB (280 words) - 17:55, 9 November 2017
• Dutra 2016 Acta Trop
  ...ore pronounced during the interaction between the parasites and peritoneal mouse macrophages.
  2 KB (308 words) - 13:41, 4 June 2018
• Barriocanal-Casado 2015 Abstract MiP2015
  ...ons, we have evaluated the effects of rapamycin treatment in the Coq9R239X mouse model. |organism=Mouse
  4 KB (568 words) - 17:44, 23 February 2020
• Rudnicki 2014 United States Patent Application Publication
  |organism=Mouse
  814 bytes (104 words) - 15:52, 13 November 2017
• Becker 2018 EMBO Rep
  ...from diet-induced obesity and insulin resistance, which was not present in mouse models with either liver- or muscle-specific depletion of CLPP. However, CL |organism=Mouse
  2 KB (283 words) - 15:52, 9 May 2018
• Ehrlicher 2020 FASEB J
  ...e to exercise training required Bcl2-mediated autophagy using a transgenic mouse model of impaired inducible autophagy (Bcl2^AAA). Mitochondrial a |organism=Mouse
  2 KB (285 words) - 15:31, 7 May 2020
• Volt 2014 Abstract The 2014 Ageing Summit
  ...signals leads to explore the activation of this pathway during ageing in a mouse model of sepsis. The lack of an effective treatment of this disease support |organism=Mouse
  2 KB (288 words) - 17:34, 7 November 2016
• Kataura 2022 Dev Cell
  ...ements of this cascade improved the survival of autophagy-deficient yeast, mouse fibroblasts, and human neurons. Our study provides a mechanistic link betwe |organism=Mouse
  3 KB (367 words) - 13:28, 28 November 2022
• Garcia-Corzo 2014 Thesis
  |organism=Mouse
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• Pamenter 2018 PLoS One
  ...o assess electron transport system (ETS) function in saponin-permeabilized mouse brain at 28 and 37°C. Respirometric analysis revealed that, at the colder |organism=Mouse
  2 KB (288 words) - 11:26, 29 July 2019
• Baeder 2016 Int J Dent
  |keywords=C2C12 mouse myoblast, Myotubes |organism=Mouse
  2 KB (296 words) - 13:07, 7 March 2020
• Salvi 2016 Oxid Med Cell Longev
  |keywords=Tempol, Buthionine sulfoximine, Oxidative stress, Mitochondria, Mouse hippocampal HT22 cells |organism=Mouse
  2 KB (284 words) - 15:06, 9 November 2016
• Mousa 2023 Cell Rep
  ...regulator of muscle mass and mitochondrial respiration. S1P disruption in mouse skeletal muscle reduces Mss51 expression and increases muscle mass and mito |organism=Mouse
  2 KB (293 words) - 10:11, 24 April 2024
• Purhonen 2014 Abstract MiP2014
  |title=Effect of ketogenic diet in mouse model of the mitochondrial hepatopathy GRACILE syndrome.
  844 bytes (112 words) - 14:18, 20 June 2016
• Xiao 2024 Sci Adv
  ...ific nonphosphorylatable FNIP1 (S220A) and phosphomimic (S220D) transgenic mouse models as well as biochemical analysis in primary skeletal muscle cells, we |organism=Mouse
  2 KB (287 words) - 15:56, 6 March 2024
• Li 2014 Mol Cell Biol
  ...first of all the development of adipocyte-like intestinal tissue, we used mouse adipocyte model 3T3-L1 cells to analyze ATAD3 functions during adipogenesis |organism=Mouse
  2 KB (288 words) - 13:30, 28 March 2018
• Maurya 2018 Cell Rep
  ...muscle oxidative metabolism. Using genetically engineered sarcolipin (SLN) mouse models and primary muscle cells, we demonstrate that SLN plays a crucial ro |organism=Mouse
  2 KB (282 words) - 08:46, 1 October 2018
• Kuzniewska 2020 EMBO Rep
  ...nto the protein supercomplexes of the respiratory chain. Importantly, in a mouse model of fragile X syndrome, Fmr1 KO mice, a common disease associated with |organism=Human, Mouse
  2 KB (291 words) - 18:02, 19 October 2021
• Ivarsson 2016 Physiol Behav
  ...Nitrate supplementation is shown to increase submaximal force in human and mouse skeletal muscles. In this study, we test the hypothesis that the increased |organism=Mouse
  2 KB (293 words) - 16:24, 27 March 2018
• Alvarez-Fischer 2013 J Neurochem
  ...co-administered with the dopaminergic neurotoxin MPTP to produce a chronic mouse model of Parkinson's disease. It has been proposed that probenecid serves t |organism=Mouse
  2 KB (305 words) - 14:12, 12 October 2017
• Fernandez-Vizarra 2013 Abstract IOC80
  ...e achieved by RNAi technology applied to cultured cell lines. Furthermore, mouse knock-out models for the gene of interest can eventually be generated to ga |organism=Human, Mouse
  2 KB (300 words) - 10:40, 9 November 2016
• Tang 2022 Elife
  |keywords=TIGAR, Acetylcholine, Cell biology, Cholinergic neurons, Mouse, Neuromuscular junction, Neuroscience, Skeletal muscle thermogenesis |organism=Mouse
  2 KB (265 words) - 14:21, 17 August 2023
• Berger 2016 Nat Commun
  ...stemness and homeostasis. Using intestinal epithelial cell (IEC)-specific mouse models, we show that loss of HSP60, a mitochondrial chaperone, activates th |organism=Mouse
  2 KB (288 words) - 11:26, 27 August 2018
• Naghipour 2023 Dis Model Mech
  ...presses contractile function while activating mitochondrial respiration in mouse hearts. https://doi.org/10.1242/dmm.049975 ...on cardiac contractile, coronary and mitochondrial function. Male C57Bl/6 mouse hearts were Langendorff perfused to assess concentration-dependent effects
  2 KB (271 words) - 15:44, 19 December 2023
• Davoudi 2014 PhD Thesis
  investigate CIII assembly and supercomplexes in a mouse model harboring the |organism=Mouse
  2 KB (333 words) - 17:29, 9 November 2017
• McLaughlin 2020b Sci Rep
  ...etics, relative to the underlying proteome, to be assessed across multiple mouse tissues (e.g., heart, brown adipose, kidney, liver). Our results support th |organism=Mouse
  2 KB (285 words) - 19:00, 29 October 2020
• Kakimoto 2019 PLoS One
  ...of obesity-induced NO. signaling on liver mitochondrial function. We used mouse strains containing mitochondrial nicotinamide transhydrogenase activity, wh |organism=Mouse
  2 KB (285 words) - 12:55, 21 June 2019
• Burtscher 2014 Abstract MiP2014
  ...pecific differences in Complex I- and Complex II-linked respiration in the mouse brain. ...rent brain regions implicated in neurodegenerative diseases of the healthy mouse and disease models while leaving sufficient amounts of sample for additiona
  3 KB (408 words) - 18:29, 10 January 2022
• Kallijarvi 2013 Abstract IOC75
  ...ion to complex III inhibition by myxothiazol decreases with age in GRACILE mouse tissues. However, in patient fibroblasts no alterations in RC activity are ...on introduced into Bcs1l causes postnatal complex III deficiency: a viable mouse model for mitochondrial hepatopathy. Hepatology 53: 437-447.
  4 KB (510 words) - 15:37, 9 November 2016
• Klepinin 2016 J Bioenerg Biomembr
  ...myocytes, Mitochondria, Neuroblastoma, Mouse neuroblastoma Neuro-2A cells, Mouse cardiac sarcoma HL-1 cell |organism=Human, Mouse, Rat
  3 KB (406 words) - 18:42, 16 January 2021
• Liu 2021 Basic Res Cardiol
  ...lic deficits. Importantly, we found the expression of the human homolog of mouse LncHrt was decreased in patients with dilated cardiomyopathy. Together, the |organism=Mouse
  3 KB (395 words) - 04:47, 21 November 2023
• MiPNet21.13 Comparison mt-preparations
  |organism=Mouse
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• Wredenberg 2013 PLoS Genet
  ...nction of MTERF3 in mitochondrial ribosomal biogenesis is conserved in the mouse, thus we identify a novel and unexpected role for MTERF3 in coordinating th
  2 KB (295 words) - 16:33, 13 November 2017
• Spinazzi 2019 Proc Natl Acad Sci U S A
  ...opez-Lluch G, Serneels L, Navas P, De Strooper B (2019) PARL deficiency in mouse causes Complex III defects, coenzyme Q depletion, and Leigh-like syndrome. ...l role ''in vivo'' remains unclear. Here we show that ''Parl'' ablation in mouse causes a necrotizing encephalomyelopathy similar to Leigh syndrome, a mitoc
  3 KB (406 words) - 02:03, 18 April 2024
• Szelechowski 2018 Sci Rep
  ...ular alterations found in human ALS patients' skin fibroblasts and SODG93A mouse motor neurons, revealing conserved changes in protein translation, folding
  2 KB (296 words) - 14:19, 17 April 2018
• Farias 2018 Int J Biol Macromol
  |keywords=B16F10 mouse skin melanoma cells, Melanoma, Metal complexes, Oxovanadium, Polysaccharide |organism=Mouse
  2 KB (322 words) - 12:15, 9 August 2019
• Wu 2012 Cell
  ...BM (2012) Beige adipocytes are a distinct type of thermogenic fat cell in mouse and human. Cell 150:366-76. |organism=Mouse
  2 KB (298 words) - 18:36, 29 February 2020
• Mourier 2014 Hum Mol Genet
  ...iration and reduced ATP production observed in Lrpprc conditional knockout mouse hearts is caused by an ATP synthase deficiency. Furthermore, the appearance |organism=Mouse
  2 KB (298 words) - 15:27, 13 November 2017
• Rudnicki 2018 Elife
  ...t-induced obesity, Endothelial cells, Glycolysis, Human biology, Medicine, Mouse |organism=Mouse
  2 KB (277 words) - 10:32, 29 July 2019
• Weber 2020 FASEB J
  ...m up, here we show for the first time that liver hCPT1AM gene therapy in a mouse model of established obesity, diabetes, and NAFLD can reduce HFD-induced de |organism=Mouse
  3 KB (396 words) - 16:06, 6 December 2021
• Zhang 2006 J Physiol
  ...rblad H (2006) Limited oxygen diffusion accelerates fatigue development in mouse skeletal muscle. J Physiol 572:551-9. doi: 10.1113/jphysiol.2005.104521 |organism=Mouse
  2 KB (333 words) - 01:55, 18 December 2021
• Horvath 2022 Antioxidants (Basel)
  ...roduction, and expression of antioxidant enzymes were measured in isolated mouse brain mitochondria. Here, we demonstrate that the ADP-stimulated respiratio |organism=Mouse
  3 KB (448 words) - 15:57, 15 December 2022
• Mouse control: Mark
  ...de is active by default, can be selected in the menu or by [Ctrl+M]. If '''Mouse control: Mark''' is enabled, specific sections of the experiment can be mar
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• Claude 1946 J Exp Med
  |organism=Mouse, Rat, Guinea pig
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• Hara 2013 Eur J Anaesthesiol
  ...nus J, Elmér E, Uchino H (2013) Early brain mitochondrial dysfunction in a mouse model of sepsis: 7AP4‐9. Eur J Anaesthesiol 30,112-112. ...was to evaluate the temporal dynamics of brain mitochondrial function in a mouse model of sepsis.
  3 KB (428 words) - 13:45, 7 March 2020
• Andersen 2014 Abstract IOC 2014-04 Schroecken
  ...mide phosphoribosyltransferase knockdown impairs mitochondrial function in mouse myoblasts. Mitochondr Physiol Network 19.02. ...ntaining mitochondrial function we generated a stable Nampt knockdown (KD) mouse myoblast (C2C12) cell line using a shRNA lentiviral approach. Nampt mRNA ex
  3 KB (404 words) - 10:30, 9 November 2016
• Wang 2020 J Mol Med (Berl)
  ...sed. Exercise improved blood pressure and systolic dysfunction in diabetic mouse hearts. The beneficial effects of exercise were also observed in a mitochon |organism=Mouse
  3 KB (425 words) - 17:23, 29 February 2020
• Konhilas 2015 Am J Physiol Heart Circ Physiol
  ...nwand LA (2015) Diet and sex modify exercise and cardiac adaptation in the mouse. Am J Physiol Heart Circ Physiol 308:H135-45. |organism=Mouse
  2 KB (297 words) - 13:22, 24 March 2015
• Karlsson 2013 Int J Biochem Cell Biol
  ...O) is a promising new therapy that has been shown to reduce mortality in a mouse model of CM. In order to further elucidate the metabolic dysfunction in CM |organism=Mouse
  2 KB (340 words) - 14:50, 13 November 2017
• Kanaan 2017 Redox Biol
  ...Grx2 controls cardiac mitochondrial dynamics and function in cellular and mouse models, and that low expression is associated with human cardiac dysfunctio |organism=Mouse
  2 KB (303 words) - 12:22, 8 January 2018
• Morton 2016 Nat Med
  ...Tst expression correlated with indices of metabolic health across diverse mouse strains. Transgenic overexpression of Tst in adipocytes protected mice from |organism=Mouse
  3 KB (372 words) - 10:08, 14 October 2021
• Sabatelli 2011 J Cell Physiol
  ...y transition pore (PTP). This effect was first identified in the Col6a1-/- mouse model and then in muscle cell cultures from UCMD and BM patients; the norma |organism=Human, Mouse
  2 KB (317 words) - 15:49, 9 November 2016
• Ziemer 2015 Dissertation
  ...p, Oxygen consumption measurements, Cyclosporin A, Cyclophilin-D-Knock-out-mouse |organism=Mouse
  2 KB (281 words) - 15:33, 7 November 2016
• Garcia-Corzo 2013 Hum Mol Genet
  ...neity in the clinical phenotypes, we have generated a Coq9 Knockin (R239X) mouse model. The lack of a functional Coq9 protein in homozygous Coq9 mutant (''C |organism=Mouse
  2 KB (314 words) - 16:38, 7 November 2016
• Hancock 2018 Elife
  |keywords=Nfe2l2, Nox4, Exercise, Human biology, Medicine, Mitochondria, Mouse, Reactive oxygen species |organism=Mouse
  2 KB (288 words) - 10:22, 29 July 2019
• Horvath 2012 Abstract Bioblast
  ...y substrate effects on mitochondrial membrane potential - experiments with mouse cardiac muscle homogenate. Mitochondr Physiol Network 17.12. The experiments were carried out in mouse heart homogenate. The measurements were performed using the O2k. We detect
  3 KB (408 words) - 02:15, 9 October 2019
• Dias 2016 Neurobiol Aging
  ...roduce reactive species such as peroxynitrite. Using the triple transgenic mouse model of AD (3xTgAD), we investigated age-dependent changes in the glutamat |organism=Mouse
  2 KB (289 words) - 18:05, 12 July 2019
• Rossetti 2021 Sci Adv
  ...ism. We used CRISPR-Cas9 genome editing to introduce this variant into the mouse Mrpp3 gene and show that the variant causes insulin resistance on a high-fa |organism=Mouse
  2 KB (295 words) - 16:55, 4 October 2021
• Valet 2015 US Patent
  |organism=Mouse
  872 bytes (124 words) - 11:54, 5 February 2018
• Sengupta 2016 Free Radic Biol Med
  ...rotects against nutrient deprivation and oxidative stress. Compared to WT, mouse lung fibroblasts (MLG) stably transfected with a degradation resistant Rev- ...receptor gamma coactivator 1‐alpha (PGC‐1α), (PPARGC1A), Preconditioning, Mouse lung fibroblasts
  3 KB (393 words) - 15:37, 23 January 2019
• Gilliam 2016 Am J Physiol Endocrinol Metab
  ...ined effect of cancer and chemotherapy in an immunocompetent breast cancer mouse model (E0771) would compromise skeletal muscle mitochondrial respiratory fu |organism=Mouse
  2 KB (318 words) - 16:42, 7 November 2016
• Dong 2024 Nat Commun
  ...itochondrial cristae and mitochondrial unfolded protein stress response in mouse hepatocytes, impairing liver mitochondrial fatty acid β-oxidation and lipi |organism=Mouse
  2 KB (301 words) - 16:44, 9 January 2024
• Paech 2018a Toxicology
  ...ory chain in HepG2 cells exposed to the toxicants for 24 h and in isolated mouse liver mitochondria exposed acutely. As a consequence, they increased mitoch |organism=Human, Mouse
  2 KB (330 words) - 14:21, 21 August 2018
• Kuznetsov 1996 J Biol Chem
  |abstract=The brindled mottled mouse (Mobr), an animal model of the Menkes' copper deficiency syndrome, was used |organism=Mouse
  2 KB (312 words) - 17:23, 16 January 2021
• Osenbroch 2009 FEBS J
  ...e accumulates oxidative damage including 8-oxoguanine, and cells from this mouse are hypersensitive to the mitochondrial oxidant menadione. Inhibitors of mi |organism=Mouse
  2 KB (329 words) - 15:08, 19 February 2015
• Nan 2017 Circ Res
  ...study the effects of TNFR2 activation on mitochondrial function. Neonatal mouse cardiac myocytes exhibited increases in mitochondrial fusion, a change that |organism=Mouse
  3 KB (433 words) - 00:27, 1 March 2020
• Valentine 2018 J Gerontol A Biol Sci Med Sci
  ...tion and its relationship with muscle mass across the lifespan, we study a mouse model with muscle-specific NFκB suppression (MISR mice). In wild type mice |organism=Mouse
  2 KB (320 words) - 15:32, 7 May 2020
• Storder 2018 MiPschool Tromso E2
  |organism=Mouse
  831 bytes (113 words) - 08:59, 19 October 2018
• Davoudi 2014 PLoS One
  ...for supercomplex formation in intact liver tissue. We used our transgenic mouse model with a homozygous c.232A>G mutation in Bcs1l leading to decreased exp |organism=Mouse
  2 KB (343 words) - 17:29, 9 November 2017
• Jacobs 2015 Abstract MiP2015
  ...ive oxidase (AOX) from the tunicate ''Ciona intestinalis'' in human cells, mouse and ''Drosophila'', as well as expression of the single-subunit NADH dehydr |organism=Human, Mouse, Drosophila, Other invertebrates
  3 KB (438 words) - 10:12, 9 November 2016
• Thapa 2022 Physiol Rep
  ...eficits that may contribute to the development of diastolic dysfunction in mouse hearts. Cardiomyocyte-specific deletion of the mitochondrial lysine acetyla |organism=Mouse
  2 KB (307 words) - 14:45, 10 August 2022
• Kettunen 2013 Thesis University of Applied Sciences - Turku
  ...lution respirometer was used to measure the oxygen consumption in isolated mouse brown fat cells obtained from the suprascapular brown fat depots. The Oxyge |organism=Mouse
  2 KB (353 words) - 12:12, 28 April 2015
• Volani 2016 Abstract MitoFit Science Camp 2016
  |title=Effects of iron imbalances on mitochondrial activity in mouse liver homogenate and permabilized rat PBMCs. ...icate that mitochondrial function testing can be successfully performed in mouse tissues as well as in isolated PBMCs from rats. Analysis of liver samples f
  3 KB (424 words) - 18:41, 10 January 2022
• Friederich-Persson 2018 Acta Physiol (Oxf)
  ...al mitochondrial leak respiration, intrarenal hypoxia and proteinuria in a mouse model of type 1 diabetes. Acta Physiol (Oxf) 223:e13058. |organism=Mouse
  2 KB (327 words) - 15:18, 2 January 2019
• Wang 2013 Hum Mol Genet
  ...ed to be a mitochondrial electron carrier, had no efficacy on UQ-deficient mouse cells. In our model with liver-specific loss of Mclk1, a large depletion of |organism=Mouse
  2 KB (333 words) - 16:56, 7 November 2016
• Zorzano Antonio
  ...working ÿon the analysis of muscle mitochondrial respiration in different mouse models under different conditions. Our work also involved the study of diff ...e working on the analysis of muscle mitochondrial respiration in different mouse models under different conditions. Our work also involved the study of diff
  2 KB (344 words) - 13:00, 19 November 2021
• Kauppila 2018 Thesis
  ...e animal models has been a to introduce mutations found in cell lines into mouse ES cells. In this thesis, two genetic approaches are presented to introduce ...t screening for pathogenic mutations, is a successful approach to generate mouse models for mitochondrial research.
  5 KB (712 words) - 11:06, 7 January 2019
• Dai 2011 Circ Res
  ...e oxygen species (ROS) to cardiac hypertrophy and failure by using genetic mouse models overexpressing catalase targeted to mitochondria and to peroxisomes. |organism=Mouse
  2 KB (319 words) - 15:40, 19 March 2015
• Oezen 2005 Hum Mol Genet
  ...ation that the accumulation of VLCFA in tissues of the ''Abcd''1-deficient mouse model for X-ALD is not due to a deficiency in VLCFA degradation, led to the |organism=Human, Mouse
  2 KB (312 words) - 13:32, 24 June 2019
• Crowder 2022 Islets
  ...st fluctuations in oxygen consumption rates. The average size of wild-type mouse islets was significantly reduced following a standard Mito Stress Test with |organism=Mouse
  2 KB (320 words) - 18:40, 31 March 2022
• Hingst 2020 Mol Metab
  ...effect(s) of AMPK on muscle metabolism during exercise, we generated a new mouse model with inducible muscle-specific deletion of AMPKα catalytic subunits |organism=Mouse
  3 KB (439 words) - 21:06, 24 September 2020
• Harrison 2015 J Appl Physiol
  ...oub M, Gnaiger E (2015) Cytochrome redox states and respiratory control in mouse and beef heart mitochondria at steady-state levels of hypoxia. J Appl Physi ...n at steady-state levels of hypoxia in mitochondria isolated from beef and mouse heart (BHimt, MHimt), comparing two species with different cardiac dynamics
  3 KB (472 words) - 13:45, 1 May 2024
• Hellgren 2020 Free Radic Biol Med
  ...To this end, we investigated mitochondrial function in the offspring of a mouse model of prenatal hypoxia. Pregnant C57 mice were subjected to either normo |organism=Mouse
  2 KB (317 words) - 13:33, 20 October 2021
• Burtscher 2020 Int J Mol Sci
  ...ce and whether such developmental changes might be compromised in the R6/2 mouse model of HD. We study OXPHOS in the striatum, hippocampus, and motor cortex |organism=Mouse
  2 KB (314 words) - 19:54, 7 December 2021
• Hellgren 2017 MiPschool Obergurgl
  We investigated mitochondrial function in the offspring from a mouse model of prenatal hypoxia. Pregnant C57 mice were subjected to either norm |organism=Mouse
  2 KB (326 words) - 16:05, 12 January 2018
• Bastian 2016 Cancer Lett
  ...usly shown to possess anticancer and antimetastatic activity in two cancer mouse models and to induce mitochondrial depolarization. This study defines the m |organism=Mouse
  2 KB (310 words) - 09:30, 23 December 2016
• Okerblom 2018 Proc Biol Sci
  ...al lineage. ''Cmah'' loss in mice exacerbates disease severity in multiple mouse models for muscular dystrophy, a finding only partially attributed to diffe |organism=Mouse
  2 KB (327 words) - 13:12, 7 May 2019
• Coleman 2018 Sci Rep
  ...physiological responses including muscle mitohormesis. Using a transgenic mouse model with skeletal muscle-specific mitochondrial uncoupling and oxidative |organism=Mouse
  2 KB (301 words) - 12:54, 21 February 2023
• Honrath 2017 Cell Death Differ
  |keywords=HT22 mouse hippocampal neuronal cell s |organism=Mouse
  2 KB (335 words) - 12:31, 28 November 2017
• Dixit 2017 Free Radic Biol Med
  ..., Fessel JP, Harrison FE (2017) Mitochondrial dysfunction in the APP/PSEN1 mouse model of Alzheimer's disease and a novel protective role for ascorbate. Fre |organism=Mouse
  3 KB (338 words) - 17:48, 20 December 2017
• Khattar 2016 J Neurosci Methods
  ...an neuronal mitochondria and can also be used to isolate mitochondria from mouse/rat/monkey brains. |organism=Human, Mouse
  2 KB (329 words) - 14:54, 13 November 2017
• Buck 2016 Abstract J Neurol Neurosurg Psychiatry
  ...ine cortex and liver turned out to show respiratory changes in the HdhQ111 mouse model, which indicates that respiratory capacities are different between ti |organism=Mouse
  3 KB (367 words) - 11:00, 10 January 2017
• Lagoutte 2010 Biochim Biophys Acta
  ...ulfide as a fuel. The SQR activity was found in mitochondria isolated from mouse kidneys, liver, and heart. We demonstrate the precedence of the SQR over th |organism=Mouse
  2 KB (343 words) - 13:30, 13 November 2017
• Ramalho 2019 J Leukoc Biol
  ...adiposity loss, hyperlipidemia, and changes in macrophage metabolism in a mouse model of streptozotocin-induced T1D. LTB4 receptor (BLT1) antagonist u75302 |organism=Mouse
  2 KB (333 words) - 15:15, 15 October 2019
• De Palma 2014 Skelet Muscle
  ...structure/activity and skeletal muscle phenotype/growth/functions using a mouse model in which nNOSμ is absent. Also, NO-induced effects and the NO pathwa We show that nNOSμ deficiency in mouse skeletal muscle leads to altered mitochondrial bioenergetics and network re
  3 KB (483 words) - 17:30, 9 November 2017
• Meszaros 2018 EBEC2018
  ...arious fuel substrates in OXPHOS-, LEAK- and ET-states in mt isolated from mouse brain, heart and liver. ...way to elucidate the underlying mechanisms, and to address the question if mouse brain is an exception or representative of a general pattern.
  3 KB (461 words) - 19:09, 10 January 2022
• MiPNet10.04 CellRespiration
  |organism=Mouse
  1 KB (135 words) - 12:51, 4 December 2019
• Canto 2009 Nature
  ...hat AMPK controls the expression of genes involved in energy metabolism in mouse skeletal muscle by acting in coordination with another metabolic sensor, th |organism=Mouse
  2 KB (323 words) - 13:25, 30 April 2021
• MiPNet18.19 IOC81
  ...homogenate. Mitochondr Physiol Network 18.05(01):1-6. [[MiPNet18.05 Amplex-Mouse-heart |»Open Access]]
  2 KB (301 words) - 02:25, 9 October 2019
• Zhao 2022 J Cell Sci
  ...enes in cardiomyocytes. We therefore provide the first genetic evidence in mouse that Drp1 is essential for RV development. Our research provides further me |organism=Mouse
  2 KB (315 words) - 13:47, 5 December 2022
• Herbst 2015 Neuroscience
  ...strated that voluntary wheel running reduces hindlimb clasping in the R6/1 mouse model of HD, which we hypothesized may be due to preservation of mitochondr |organism=Mouse
  2 KB (347 words) - 17:24, 7 November 2016
• Zhang 2019 Nephron
  A DKD model was constructed using streptozocin (STZ), and an immortalized mouse podocytes cell line MPC-5 was used. Renal histology and western blot were u |organism=Mouse
  2 KB (324 words) - 11:18, 3 March 2020
• Claiborne 2013 Thesis
  ...capacity despite present muscle mitochondrial dysfunction in the TAZ shRNA mouse model of human barth syndrome. Master's Thesis 67pp. mouse model of Barth Syndrome (90% taz-deficient), and examined the effect of exe
  3 KB (420 words) - 17:24, 9 November 2017
• Yuzefovych 2013 Endocrinology
  ...3) Alteration of mitochondrial function and insulin sensitivity in primary mouse skeletal muscle cells isolated from transgenic and knockout mice: role of O |organism=Mouse
  2 KB (325 words) - 15:21, 18 May 2022
• Tegelberg 2017 Orphanet J Rare Dis
  ...type with encephalomyopathy, partially phenocopied in a '''Bcs1l''' mutant mouse model. Orphanet J Rare Dis 12:73. ...g early postnatal mortality, but were partially corroborated in a knock-in mouse model of ''BCS1L'' deficiency.
  3 KB (473 words) - 11:12, 25 June 2019
• McManus 2016 Abstract MitoFit Science Camp 2016
  ..., motor impairments, and finally cognitive decline. The ND6^P25L mouse provides the first direct demonstration that mtDNA variation alone is suffi
  4 KB (502 words) - 09:02, 1 July 2016
• Zhu 2022 Metabolism
  ...gh fat diet-induced obese mice were subjected to treadmill training. Alpha mouse liver 12 (AML12) cells were used for ''in vitro'' studies. |organism=Mouse
  2 KB (324 words) - 15:24, 26 September 2022
• Harris 2015 Diabetes
  ...e-body energy homeostasis remains unclear. To examine this, we developed a mouse line with skeletal muscle PLIN5 overexpression (MCK-Plin5). We show that MC |organism=Mouse
  2 KB (319 words) - 14:50, 18 October 2018
• Heeman 2011 J Cell Sci
  ...ellular calcium (Ca(2+)) homeostasis in PINK1-knockdown and PINK1-knockout mouse cells, both in basal metabolic conditions and after physiological stimulati |organism=Mouse
  2 KB (311 words) - 14:37, 27 March 2018
• Serafini 2016 Abstract Mito Xmas Meeting Innsbruck
  ...FRET values of a FRET ER-Mitochondria proximity probe (FEMP) expressed in mouse embryonic fibroblasts transduced with lentiviral particles carrying shRNAs |organism=Mouse
  2 KB (334 words) - 17:32, 14 December 2016
• Grimpo 2014 Comp Biochem Physiol A Mol Integr Physiol
  ...troch M (2014) Metabolic depression during warm torpor in the Golden spiny mouse (''Acomys russatus'') does not affect mitochondrial respiration and hydroge ...causes mitochondrial depression during torpor by studying the Golden spiny mouse (''Acomys russatus''), a desert rodent which performs daily torpor at high
  2 KB (327 words) - 11:08, 27 March 2018
• Gupta 2021 Sci Rep
  ...amily, less is known about its role in cardiac physiology. Transgenic (Tg) mouse with cardiomyocyte-specific overexpression of miRNA-7 was generated to dete |organism=Mouse
  2 KB (327 words) - 15:12, 15 November 2021
• Bock 2015 Thesis
  |organism=Mouse
  1,010 bytes (121 words) - 16:58, 9 November 2017
• MiPNet15.12 IOC57 Druskininkai LT
  ...homogenate. Mitochondr Physiol Network 18.05(01):1-6. [[MiPNet18.05 Amplex-Mouse-heart |»Open Access]]
  2 KB (306 words) - 02:28, 9 October 2019
• Zhou 2019 Int J Mol Sci
  ...otential toxicological effects by synthetic cathinones on C2C12 myoblasts (mouse skeletal muscle cell line). We exposed C2C12 myoblasts to 3-methylmethcathi |organism=Mouse
  2 KB (302 words) - 14:06, 3 April 2019
• Ruzickova 2019 Thesis
  ...ndria from donor cells to mtDNA-damaged tumour cells has been described in mouse models of melanoma and mammary tumours. It can be mediated by different mec |organism=Mouse
  3 KB (364 words) - 18:06, 15 June 2020
• MiPNet15.11 IOC58
  ...homogenate. Mitochondr Physiol Network 18.05(01):1-6. [[MiPNet18.05 Amplex-Mouse-heart |»Open Access]]
  2 KB (306 words) - 02:28, 9 October 2019
• Reis 2016 Aging (Albany NY)
  ...As and their processing enzymes - mainly Dicer - that occurs with aging in mouse white adipose tissue (WAT). Here we used fat-specific Dicer knockout mice ( |organism=Mouse
  2 KB (338 words) - 17:48, 23 February 2020
• Dulac 2020 J Physiol
  ...obtained intramuscular injection of Adeno-Associated Virus (AAV) in adult mouse skeletal muscle. Knocking down Drp1 for 4 months resulted in very severe mu |organism=Mouse
  3 KB (329 words) - 14:16, 27 October 2021
• MiPNet18.18 IOC77
  ...homogenate. Mitochondr Physiol Network 18.05(01):1-6. [[MiPNet18.05 Amplex-Mouse-heart |»Open Access]]
  2 KB (294 words) - 02:25, 9 October 2019
• Johnson 2018 J Mol Cell Cardiol
  ...icient to prevent cardiomyopathy and skeletal myopathy ''in vivo'' using a mouse model of BTHS. To this end we crossed mice that overexpress catalase in the |organism=Mouse
  2 KB (335 words) - 02:29, 1 March 2020
• Schober 2022 Hum Mol Genet
  ...those previously described in early-onset cases. We demonstrate using both mouse and fruit fly models that impairment of SAH, rather than SAM, transport acr |organism=Mouse, Drosophila
  2 KB (334 words) - 10:56, 6 September 2022
• Guerrero 2010 Mol Cell Biochem
  ...microtubular network stabilizing STOP protein with mitochondria in rat and mouse cardiac and skeletal muscles by confocal microscopy and oxygraphy. Intracel |organism=Mouse, Rat
  2 KB (346 words) - 16:56, 6 September 2022
• Kruska 2015 Biochim Biophys Acta
  Here, we investigate astrocytes from wild-type control and a genetic X-ALD mouse model (Abcd1-knockout), exposed |organism=Mouse
  3 KB (332 words) - 15:01, 13 November 2017
• Makrecka-Kuka 2015 Biomolecules
  ...>2</sub>O₂ flux, Amplex Red, HEK 293T, Mouse brain homogenate, Mouse cardiac mitochondria |organism=Human, Mouse
  4 KB (484 words) - 19:56, 7 January 2024
• Salazar-Petres 2022 Biol Reprod
  ...) and metabolic signaling (AMPK, AKT, and PPARγ) pathways. Thus, in normal mouse pregnancy, placental structure, function, and mitochondrial phenotype are d |organism=Mouse
  3 KB (355 words) - 17:31, 30 November 2022
• Mayeuf-Louchart 2019 Cell Rep
  ...re the differentiation of brown adipocytes from adipose progenitors in the mouse embryo. We demonstrate that the formation of multiple lipid droplets (LDs) |organism=Mouse
  2 KB (325 words) - 11:48, 22 December 2020
• Burtscher 2020 eNeuro
  ...i C, Lashuel HA (2020) Pronounced α-synuclein pathology in a seeding-based mouse model is not sufficient to induce mitochondrial respiration deficits in the |organism=Mouse
  3 KB (351 words) - 12:14, 3 May 2022
• MiPNet16.05 IOC63
  ...homogenate. Mitochondr Physiol Network 18.05(01):1-6. [[MiPNet18.05 Amplex-Mouse-heart |»Open Access]]
  2 KB (314 words) - 20:10, 25 February 2020
• Ferguson 2020 Endocrinology
  ...lectively, these studies provide further evidence supporting the potential value of MR as a therapeutic target for conditions associated with metabolic synd |organism=Mouse
  2 KB (346 words) - 10:54, 3 May 2024
• Neuzil 2022 Abstract Bioblast
  ...on after partial hepatectomy (PHx), with liver re-growth after 60 % PHx in mouse in 5-6 days. Consistent with the notion that this process requires highly r
  2 KB (343 words) - 08:40, 28 July 2022
• Boutant 2014 Mol Metab
  We have used a mouse model of moderate SIRT1 overexpression, under the control of its natural pr |organism=Mouse
  2 KB (323 words) - 17:31, 20 August 2023
• Hamilton 2016 Physiol Rep
  ...stemic metabolism, insulin action, and cardiac mitochondrial function in a mouse model of metabolic dysfunction (ovariectomy [OVX], insulin resistance, hype |organism=Mouse
  2 KB (308 words) - 11:06, 2 August 2017
• Jiang 2019 EMBO Rep
  ...for mtDNA gene expression. Here, we report that ''Tefm'' is essential for mouse embryogenesis and that levels of promoter-distal mitochondrial transcripts |organism=Mouse
  2 KB (337 words) - 17:19, 29 October 2019
• MiPNet18.20 IOC78
  ...homogenate. Mitochondr Physiol Network 18.05(01):1-6. [[MiPNet18.05 Amplex-Mouse-heart |»Open Access]]
  2 KB (309 words) - 02:26, 9 October 2019
• Lee 2017 Am J Physiol Endocrinol Metab
  ...sponse following endurance training. First, we established and validated a mouse exercise-training-detraining protocol. Second, using multiple physiological |organism=Mouse
  3 KB (359 words) - 10:03, 5 May 2017
• Wuest 2021 Int J Mol Sci
  ...cerbated diastolic dysfunction and reduced ejection fraction in a diabetes mouse model vulnerable for metabolic derangements. We therefore conclude that dox |organism=Mouse
  3 KB (333 words) - 15:09, 8 February 2022
• Dutta 2013 Autophagy
  ...a, as assessed by apoptotic marker activation and viability assays in both mouse atrial HL-1 cardiomyocytes and human ventricular AC16 cells. Importantly, r |organism=Mouse
  3 KB (361 words) - 17:22, 23 February 2020
• Stankova 2020 Int J Mol Sci
  ...ová K, Červinková Z (2020) Adaptation of mitochondrial substrate flux in a mouse model of nonalcoholic fatty liver disease. Int J Mol Sci 21:E1101. |organism=Mouse
  2 KB (351 words) - 10:38, 4 January 2021
• Chennamsetty 2016 Cell Rep
  ...mine the cellular mechanism linking ''NAT2'' to IR and find that ''Nat1'' (mouse ortholog of ''NAT2'') is co-regulated with key mitochondrial genes. RNAi-me |organism=Mouse
  2 KB (317 words) - 11:55, 9 November 2017
• Stepanova 2016 Biochim Biophys Acta
  ...significant, but still controversial topic. We found that complex II from mouse heart and brain tissue has similar affinity to OAA and that only a fraction |organism=Mouse
  3 KB (384 words) - 10:02, 24 September 2018
• Hall 2013 Biochim Biophys Acta
  ...ent ATP leakage to the extracellular medium. Studies with freshly isolated mouse liver mitochondria corroborated with bioenergetic findings and demonstrated |organism=Mouse
  3 KB (327 words) - 11:13, 22 November 2023
• Christian 2019 Respir Physiol Neurobiol
  ...F, Jorge S (2019) NADH-linked mitochondrial respiration in the developing mouse brain is sex-, age- and tissue-dependent. Respir Physiol Neurobiol 266:156- |organism=Mouse
  3 KB (358 words) - 13:59, 12 June 2019
• Ruiz 2017 Brain Pathol
  ...patient-derived fibroblasts and spinal cords of the PLP-tg^66/66 mouse model, and identified redox imbalance, with altered antioxidant defense and |organism=Human, Mouse
  3 KB (433 words) - 14:59, 2 January 2019
• Stiban 2019 MiP2019
  |organism=Mouse
  941 bytes (126 words) - 13:39, 22 August 2019
• Szibor 2019 Biochim Biophys Acta Bioenerg
  ...) Bioenergetic consequences from xenotopic expression of a tunicate AOX in mouse mitochondria: switch from RET and ROS to FET. Biochim Biophys Acta Bioenerg ...d CIV. Here, we used ''Ciona intestinalis'' AOX xenotopically expressed in mouse mitochondria to study how respiratory states impact the Q poise and how AOX
  3 KB (458 words) - 12:35, 3 April 2021
• Sundstroem 2015 PhD Thesis
  ...sed automated quantification of nanoparticle-labeled melanoma cells in the mouse brain after intracardiac injection. We proposed that this model could help |organism=Mouse
  3 KB (375 words) - 16:15, 13 November 2017
• Boel 2020 J Exp Biol
  ...'Mus mattheyi'', ∼5 g, and ''Mus minutoides'', ∼7 g) with the larger house mouse (''Mus musculus'', ∼22 g). Oxygen consumption rates were measured from |organism=Mouse
  3 KB (352 words) - 18:01, 16 April 2020
• Gonnot 2023 Nat Commun
  ...el of SERCA2 at serine 663 is increased in ischemic hearts of patients and mouse. Analyses on different human cell lines indicate that preventing serine 663 |organism=Mouse
  2 KB (330 words) - 16:53, 22 June 2023
• Pfeiffer 2017 Free Radic Biol Med
  ...n mitochondrial shape and function in knockout (KO), wild type and rescued mouse embryonic fibroblast cell lines. Mitochondria of KO cells were more fragmen |organism=Mouse
  3 KB (365 words) - 15:42, 29 November 2017
• Reutzel 2018 Oxid Med Cell Longev
  ...ve secoiridoids were tested on cognition and ATP levels in a commonly used mouse model for brain aging. Over 6 months, female NMRI mice (12 months of age) w |organism=Mouse
  2 KB (343 words) - 10:20, 29 July 2019
• Krumschnabel 2013 Abstract MiP2013
  ...s for respiratory OXPHOS analysis in comparative mitochondrial physiology: mouse and trout – heart and liver. Mitochondr Physiol Network 18.08. ...pect a better mt-model for human mt-cardiac function [4] than mouse heart. Mouse heart and liver homogenates were measured at 37 °C using an identical subs
  6 KB (817 words) - 18:28, 10 January 2022
• Chubanov 2016 Elife
  ...ismal balance of Mg²⁺. Capitalizing on a set of newly generated mouse models, we provide an integrated mechanistic model of the regulation of org ...physics, Human biology, Intestine, Kidney, Longevity, Magnesium, Medicine, Mouse, Placenta, Structural biology, Trophoblast stem cells, Hap1 cells
  2 KB (343 words) - 10:50, 22 November 2017
• Makrecka-Kuka 2020 Cardiovasc Drugs Ther
  ...0) Empagliflozin protects cardiac mitochondrial fatty acid metabolism in a mouse model of diet-induced lipid overload. Cardiovasc Drugs Ther 34:791-97. |organism=Mouse
  3 KB (338 words) - 16:19, 2 December 2021
• Petrick 2019 Biochem J
  ...process remains elusive. Therefore, using permeabilized muscle fibers from mouse skeletal muscle, we aimed to determine if acute exercise altered mitochondr |organism=Mouse
  3 KB (359 words) - 07:00, 20 April 2020
• Mahmoud 2023 Pharmacol Res
  ...l (CBG), suppress HRPC development in the TRansgenic Adenocarcinoma of the Mouse Prostate (TRAMP) model by reprogramming metabolic and oncogenic signaling. |organism=Mouse
  3 KB (336 words) - 17:20, 6 February 2023
• Zabielski 2016 Diabetes
  |keywords=C2C12 mouse myoblast, Myotubes |organism=Mouse
  3 KB (354 words) - 15:41, 28 March 2018
• Gillardon 2007 Proteomics
  ...t in Alzheimer's disease patients and has also been detected in transgenic mouse models. In the present study, we analyzed proteomic changes in synaptosomal |organism=Mouse
  3 KB (345 words) - 16:14, 17 February 2015
• MacPherson 2016 Am J Physiol Cell Physiol
  ...otein kinase, Adipose tissue triglyceride lipase, Lipolysis, Mitochondria, Mouse, White adipose tissue |organism=Mouse
  2 KB (334 words) - 14:45, 31 July 2017
• Ravasz 2017 Neurochem Int
  ...ctionality of the adenine nucleotide translocase during anoxia in isolated mouse brain and liver mitochondria. GABA eliminated SLP, and this was rescued by |organism=Mouse
  3 KB (357 words) - 08:16, 28 March 2018
• Cecatto 2023 BPS2023 San Diego
  ...gher in kidney homogenate and ― as expected ― much higher in permeabilized mouse cardiac fibers. Under these experimental conditions the ratio of FAO- to NS |organism=Mouse
  3 KB (468 words) - 17:22, 22 March 2023
• Rindler 2013 J Biol Chem
  ...omics method to measure antioxidant enzyme expression in heart tissue in a mouse model of diet-induced obesity. This experiment showed a rapid and specific |organism=Mouse
  2 KB (352 words) - 15:38, 30 April 2015
• Seillier 2015 EMBO Mol Med
  ...egulator of redox-driven metabolic syndrome and provides a new preclinical mouse model for metabolic syndrome clinical research. |organism=Human, Mouse
  2 KB (337 words) - 23:53, 18 March 2018
• Corrochano 2018 Hum Mol Genet
  ...el disease modifiers, we performed an unbiased mutagenesis screen on an HD mouse model, identifying a mutation in the skeletal muscle voltage-gated sodium c |organism=Mouse
  2 KB (334 words) - 15:22, 2 January 2019
• Jackson 2017 Cancer Res
  ...se to complex energetic, enzymatic, and metabolic cues. Here we utilized a mouse model of hepatocyte-specific PDC inactivation to determine the need for thi |organism=Mouse
  2 KB (333 words) - 14:39, 7 August 2019
• Arnoux 2018 Elife
  ...ngton disease, Cortical microcircuits, In vivo calcium imaging, Metformin, Mouse, Neuronal hyperactivity, Neuroscience |organism=Mouse
  2 KB (331 words) - 10:20, 14 October 2021
• Prouteau-Angebault 2013 Abstract IOC75
  ...ardiolipins involved in the mitochondrial respiratory chain defect in OPA1 mouse model? Mitochondr Physiol Network 18.03. We generated and characterized an Opa1 mouse model carrying the mutation c.2708delTTAG and showed that it presents a syn
  4 KB (542 words) - 16:47, 26 March 2018
• Ferreira 2019 EMBO J
  ...tochondria and its potential effects on metabolism. We generated yeast and mouse models with error-prone and hyper-accurate mitochondrial translation, and f |organism=Mouse
  3 KB (344 words) - 11:24, 3 March 2020
• Ravasz 2018 Abstract The evolving concept of mitochondria
  ...by Complex I during anoxia, supporting substrate-level phosphorylation in mouse liver mitochondria. |organism=Mouse
  3 KB (359 words) - 19:05, 10 January 2022
• Roy 2022 Am J Pathol
  ...test the function of SLC25A34 ''in vivo'', a hepatocyte-specific knockout mouse was generated, and loss of SLC25A34 was assessed in mice maintained on a ch |organism=Mouse
  2 KB (363 words) - 14:15, 22 November 2022
• Hill 2015 Abstract MiPschool London 2015
  ...ne potential. Importantly, in an ''in vivo'' autoimmune encephalomyelitis mouse, a model of demyelinating disease, the compound significantly improved clin |organism=Mouse
  3 KB (455 words) - 20:08, 7 March 2020
• Stier 2013 Front Zool
  ...n blood of the zebra finch compared to a size-matched mammalian model, the mouse. |organism=Mouse, Birds
  3 KB (371 words) - 09:57, 9 November 2016
• Cejvanovic 2018 Free Radic Biol Med
  ...lsen HE (2018) Iron induced RNA-oxidation in the general population and in mouse tissue. Free Radic Biol Med 115:127-35. |organism=Mouse
  3 KB (345 words) - 17:43, 31 January 2018
• Thomsen 2017 Neurobiol Aging
  ...his decline. Using hippocampus and frontal cortex of a segmental progeroid mouse model lacking Cockayne syndrome protein B (CSB^m/m) and C57Bl/6 ( |organism=Mouse
  2 KB (334 words) - 17:33, 25 February 2020
• MiPNet17.19 IOC69
  ...homogenate. Mitochondr Physiol Network 18.05(01):1-6. [[MiPNet18.05 Amplex-Mouse-heart |»Open Access]]
  3 KB (343 words) - 02:26, 9 October 2019
• Littlejohns 2014 PLoS One
  To characterize a non-obese mouse model of high-fat diet, assess the vulnerability of hearts to reperfusion i |organism=Mouse
  3 KB (366 words) - 09:17, 8 November 2016
• Schwarzkopf 2015 Neuroscience
  ...neurotoxic increase of extracellular glutamate, which was observed in the mouse striatum during MCAO, was strongly reduced in triheptanoin-fed mice while g |organism=Mouse
  3 KB (351 words) - 15:58, 13 November 2017
• Pardo 2018 FASEB J
  ...drial biogenesis plays on glucose homeostasis following CR, we generated a mouse model devoid of the coactivators peroxisome proliferator-activated receptor |organism=Mouse
  2 KB (337 words) - 13:17, 17 April 2019
• Liu 2016 EMBO Mol Med
  ...function in myocytes. Restoration of the expression of miR-499 in the mdx mouse model of Duchenne muscular dystrophy (DMD) reduced the severity of DMD. Thu |organism=Mouse
  2 KB (345 words) - 01:05, 1 March 2020
• Copy to clipboard
  :::* '''[[Mark statistics]] - Copy to clipboard''' - Left mouse click to select a single data cell of the table, copy by Ctrl+C, and paste
  844 bytes (133 words) - 11:29, 25 March 2022
• Ali 2015 Abstract MiP2015
  |title=Mitochondrial function and ROS homeostasis in young mouse heart and brain: the sex factor! |organism=Mouse
  3 KB (366 words) - 10:10, 9 April 2018
• Vercellino 2021 Nature
  ...ion. Here we present the first, to our knowledge, structures of mammalian (mouse and ovine) CIII2CIV and its assembly intermediates, in different conformati |organism=Mouse
  3 KB (414 words) - 18:51, 4 October 2023
• Gariani 2016 J Hepatol
  ...e therapeutic potential of poly ADP-ribose polymerase (PARP) inhibitors in mouse models of NAFLD. ...macological therapy. PARP inhibitors given as a treatment in two different mouse models of NAFLD confer a protection against its development. PARP inhibitor
  3 KB (499 words) - 14:08, 2 August 2017
• Djordjevic 2017 Neuroscience
  ...c alterations in mitochondrial function and NF-κB signaling in the TgCRND8 mouse model of Alzheimer's disease. Neuroscience 361:81-92. |organism=Mouse
  3 KB (375 words) - 16:28, 29 November 2017
• Hansen 2015 Shock
  ...ds=Ceramides, Dihydroceramides, Mitochondrial dynamics, Respiration, C2C12 mouse myotubes |organism=Mouse
  3 KB (365 words) - 14:31, 13 November 2017
• Halling 2019 Am J Physiol Endocrinol Metab
  ...timulated respiration, ROS emission and mitochondrial network structure in mouse skeletal muscle during aging and exercise training. |organism=Mouse
  3 KB (351 words) - 13:00, 7 March 2020
• Phosphoenolpyruvate carboxykinase
  ...nse of GTP. PEPCK is a cytoplasmatic enzyme involved in gluconeogenesis in mouse and rat liver, but 'is found in the mitochondria in the rabbit and chicken,
  1 KB (135 words) - 20:44, 30 April 2022
• Larche 2006 J Am Coll Cardiol
  ...test whether mitochondrial dysfunction is causative of sepsis sequelae, a mouse model of peritonitis sepsis induced by cecal ligation and perforation. Inhi |organism=Human, Mouse
  3 KB (360 words) - 11:50, 22 December 2020
• Harrison 2014 Abstract MiP2014
  ...tionship between cytochrome redox state and oxygen consumption in isolated mouse and beef heart mitochondria during hypoxia. ...initial steep decrease in the oxidation fraction of cytochrome ''c'' to a value of ''j'' of approximately 0.7 followed by a plateaux and a further steep de
  3 KB (363 words) - 22:47, 14 November 2022
• Cho 2022 BMC Med
  ...ining attenuates pulmonary inflammation and mitochondrial dysfunction in a mouse model of high-fat high-carbohydrate-induced NAFLD. https://doi.org/10.1186/ |organism=Mouse
  3 KB (348 words) - 19:37, 15 November 2022
• De Oliveira 2011 Neuroscience
  ...f the involvement of such alterations in AD patients, our data render this mouse model of hypercholesterolemia a useful approach to comprehend the molecular |organism=Mouse
  3 KB (335 words) - 09:00, 5 May 2020
• Dobrowolski 2021 Mol Genet Metab
  ...ve stress contribute to osteopenia in the Pah^enu2 classical PKU mouse. Mol Genet Metab 132:173-79. ...a is not fully penetrant in patients, the Pah^enu2 classical PKU mouse is universally osteopenic, making it an ideal model of the phenotype. Pah<s
  3 KB (365 words) - 15:00, 20 October 2021
• Lopez 2017 PLOS ONE
  |abstract=MPTP-mouse model constitutes a well-known model of neuroinflammation and mitochondrial |organism=Mouse
  2 KB (348 words) - 05:59, 8 May 2020
• Abdurrachim 2014 Biochim Biophys Acta
  ...sity-related cardiomyopathy is caused by impaired cardiac energetics. In a mouse model of high-fat diet (HFD)-induced obesity, we applied ''in vivo'' cardia |organism=Mouse
  3 KB (369 words) - 14:27, 27 March 2018
• Makrecka 2015 Fatty Acid Oxidation O2k-Network Discussion Forum
  |organism=Mouse, Rat
  1,013 bytes (143 words) - 14:24, 27 March 2018
• Rouet 2017 US Patent
  |organism=Human, Mouse
  1 KB (157 words) - 12:47, 5 February 2018
• Zeh 2013 Thesis
  ...2013) Neurological and molecular biological characterisation of the mutant mouse line Tom40. Thesis Technische Universität München 243pp. ...ery consists of several translocases. By gene trap mutagenesis, a knockout mouse model for the translocase of the outer mitochondrial membrane (Tom) 40 was
  5 KB (679 words) - 16:36, 13 November 2017
• Keller 2018 MiP2018
  |organism=Mouse
  1,002 bytes (131 words) - 09:41, 20 August 2018
• Musi 2018 Aging Cell
  ..., cellular remodeling, and metabolic dysfunction. Using four AD transgenic mouse models, we found that NFTs, but not Aβ plaques, display a senescence-like |organism=Mouse
  3 KB (362 words) - 13:08, 17 April 2019
• Dolezal 2017 J Biol Chem
  ...cancer that frequently overexpresses the c-Myc (Myc) oncoprotein. Using a mouse model of Myc-induced HCC, we studied the metabolic, biochemical, and molecu |organism=Mouse
  3 KB (340 words) - 15:06, 7 August 2019
• MiPNet20.13 Safranin mt-membranepotential
  |organism=Mouse
  1 KB (148 words) - 11:26, 27 October 2023
• Lamberti 2015 Cold Spring Harb Protoc
  |organism=Mouse
  1 KB (146 words) - 16:10, 9 November 2016
• Lemieux 2017 bioRxiv 103457
  ...ng pathway control of mitochondrial respiratory capacity by temperature in mouse heart: electron flow through the Q-junction in permeabilized fibers. Sci Re ...l and capacity of mitochondrial respiration in permeabilized fibers of the mouse heart. Biochim Biophys Acta, EBEC Short Reports Suppl 14 (2006):201-2. - [[
  4 KB (513 words) - 18:56, 22 May 2019
• Leduc-Gaudet 2021 bioRxiv
  ...ophagosome formation. Using an inducible and muscle-specific Atg7 knockout mouse model (Atg7^iSkM-KO), we investigated the functional importance o |organism=Mouse
  3 KB (373 words) - 14:13, 27 October 2021
• Dobrowolski 2022 Mol Genet Metab
  ...E (2022) Comparative metabolomics in the Pah^enu2 classical PKU mouse identifies cerebral energy pathway disruption and oxidative stress. https:/ ...sue response, metabolomics was applied to Pah^enu2 classical PKU mouse blood, liver, and brain. In blood and liver over-represented analytes were
  3 KB (370 words) - 17:17, 30 November 2022
• Johnson 2016 Stem Cells Dev
  .... To understand the origins of this disease, we have generated a series of mouse embryonic stem cell lines from blastocysts that were wild type, heterozygou |organism=Mouse
  3 KB (391 words) - 16:22, 9 November 2016
• Kaplanova 2015 Abstract MiP2015
  ...role of TMEM70 in experimental animals shows that Tmem70 deficiency in the mouse has lethal consequences that are analogous to TMEM70 dysfunction in humans. |organism=Mouse
  3 KB (360 words) - 16:27, 4 September 2015
• King 2017 ANDA2017
  ...ndrial function and insulin sensitivity will be tested in an inducible cre mouse model, currently breeding in our laboratory. |organism=Mouse
  3 KB (357 words) - 10:04, 15 December 2017
• Chergova 2015 Abstract MiPschool London 2015
  ...blation. ''In vivo'' we will evaluate physiological angiogenesis using the mouse retinal neovascularization model [4] in the conditional endothelial knock o |organism=Human, Mouse
  3 KB (498 words) - 15:56, 9 November 2016
• Latina 2021 Acta Neuropathol Commun
  ...logical N-terminal truncated tau peptide reduces retinal degeneration in a mouse model of Alzheimer's Disease. Acta Neuropathol Commun 9:38. |keywords=Alzheimer’s Disease, Mouse model, Neurodegeneration, Retina, Tau, Β-amyloid
  4 KB (480 words) - 11:20, 8 July 2021
• Nemeth 2017 Thesis
  |organism=Mouse
  1 KB (155 words) - 10:52, 21 June 2019
• Doerrier 2014 Life Sci
  Main methods. Here, we analyzed mitochondrial respiration in isolated mouse liver mitochondria with different substrate combinations (glutamate/malate, |organism=Mouse
  3 KB (352 words) - 00:49, 10 February 2020
• Kopitar-Jerala 2019 MiP2019
  |organism=Mouse
  1 KB (141 words) - 15:30, 2 October 2019
• Fink 2016 Am J Physiol Regul Integr Comp Physiol
  |abstract=Recently, we used an ADP recycling approach to examine mouse skeletal muscle (SkM) mitochondrial function over respiratory states interm |organism=Mouse
  3 KB (375 words) - 01:41, 3 April 2023
• Berschneider 2016 Thesis
  |keywords=MLE12 Mouse lung epithelial cells |organism=Mouse
  6 KB (770 words) - 16:57, 9 November 2017
• Schumann 2021 Commun Biol
  ...at the plasma membrane and report on the effect of Slc16a13 deletion in a mouse model. We show that Slc16a13 increases mitochondrial respiration in the liv |organism=Mouse
  2 KB (341 words) - 11:25, 8 July 2021
• Chicco 2012 Abstract Bioblast
  ...thy. In this study, the cardiac mitochondrial phenotype of a new Taz shRNA mouse model of BTHS was characterized. [[High-resolution respirometry]] revealed ...h MJ, Strauss A, Khuchua Z (2011) Cardiac and skeletal muscle defects in a mouse model of human Barth syndrome. J Biol Chem 286: 899-908. Open Access]
  4 KB (511 words) - 15:57, 7 November 2016
• Lindquist 2015 Abstract IOC106
  ...e=Alteraas EK, Lindquist C, Berge RK, Bjorndal B (2015) OXPHOS capacity in mouse liver altered by modified fatty acids that inhibit or stimulate beta-oxidat |organism=Mouse
  3 KB (391 words) - 15:11, 13 November 2017
• Musi 2020 Aging Cell
  ..., cellular remodeling, and metabolic dysfunction. Using four AD transgenic mouse models, we found that NFTs, but not Aβ plaques, display a senescence-like |organism=Mouse
  3 KB (365 words) - 19:43, 22 September 2020
• Chin 2017 US Patent
  |organism=Mouse
  1 KB (142 words) - 16:06, 26 February 2018
• McCommis 2020 Nat Metab
  ...e show that MPC1 and MPC2 expression is downregulated in failing human and mouse hearts. Mice with cardiac-specific deletion of Mpc2 (CS-MPC2^-/-) |organism=Mouse
  2 KB (350 words) - 09:29, 4 September 2023
• Truksa 2015 Antioxid Redox Signal
  ...The inhibition of mitochondrial transcription was replicated in vivo in a mouse model of HER2high breast cancer, where MitoVES lowered the level of mtDNA t |organism=Human, Mouse
  3 KB (382 words) - 15:14, 9 November 2016
• Francisco 2018 J Neurochem
  ...NNT activity and mitochondrial redox balance in the brain using a congenic mouse model carrying the mutated ''Nnt'' gene from the C57BL/6J strain. The absen |organism=Mouse
  3 KB (405 words) - 13:20, 17 April 2019
• Krumschnabel 2014 Abstract MiP2014
  ...chondrial respiration media. Finally, we show an application example using mouse brain mitochondria as an experimental model for the simultaneous measuremen |organism=Mouse
  3 KB (357 words) - 18:31, 10 January 2022
• Fisher-Wellman 2019 Cell Rep
  ...to evaluate three disparate models of mitochondrial hyperacylation in the mouse heart caused by genetic deletion of malonyl CoA decarboxylase (MCD), SIRT5 |organism=Mouse
  2 KB (332 words) - 13:18, 12 August 2019
• Leduc-Gaudet 2023 Nat Commun
  ...scle integrity ''in vivo''. Mytho is significantly up-regulated in various mouse models of skeletal muscle atrophy. Short term depletion of MYTHO in mice at |organism=Mouse
  3 KB (370 words) - 13:35, 14 March 2023
• Gonzalez-Mariscal 2019 FASEB J
  ...eveloped a skeletal muscle-specific CB1R-knockout (Skm-CB1R^-/-) mouse to study the specific role of CB1R in muscle. Muscle-CB1R ablation prevente |organism=Mouse
  2 KB (356 words) - 10:06, 14 August 2019
• Martines 2019 Sci Rep
  ...metabolic adaptations in the liver may underlie the robustness of this KO mouse. WT and KO mice were given a high- or low-fat diet and subsequently fasted. |organism=Mouse
  2 KB (347 words) - 15:53, 24 October 2019
• Cooper 2019 Exp Physiol
  ...eurons has commonly focused on glucose metabolism. Here, we tested whether mouse sensory neurons and nerves have the capacity to metabolize fat-based fuels |organism=Mouse
  2 KB (367 words) - 13:23, 7 March 2020
• Yang 2010 Cancer Biol Ther
  ...ewer GJ, Singh KK, Nie D (2010) Impairment of mitochondrial respiration in mouse fibroblasts by oncogenic H-RAS(Q61L). Canc Biol Ther 9:122-33. |organism=Mouse
  3 KB (399 words) - 17:34, 29 February 2020
• Volt 2016 J Pineal Res
  ...s, and mitochondrial bioenergetics was analyzed during aging and sepsis in mouse heart. Our results suggest that the sole NF-κB activation does not explain |organism=Mouse
  3 KB (361 words) - 08:04, 21 February 2020
• Crouch 2017 PLOS ONE
  ...eficits in physical performance and ''in vivo'' mitochondria function in a mouse model of chemotherapy late effects. PLOS ONE 12:e0181086. |organism=Mouse
  2 KB (326 words) - 17:53, 22 November 2017
• Komlodi 2018b EBEC2018
  ...by Complex I during anoxia, supporting substrate-level phosphorylation in mouse liver mitochondria. We show that in isolated mouse liver mitochondria Complex I utilizes endogenous quinones oxidizing NADH du
  3 KB (461 words) - 09:59, 3 May 2022
• Lancel 2012 PLoS One
  ...noxide improves cardiac function and mitochondrial population quality in a mouse model of metabolic syndrome. PLoS One 7:e41836. |organism=Mouse
  3 KB (373 words) - 11:48, 22 December 2020
• Kressig 2013 Abstract IOC79
  Mitochondrial respiration was decreased in PASMC of both mouse strains after exposure to hypoxia (48 h, 1% oxygen), but unchanged in PASMC |organism=Mouse
  3 KB (409 words) - 14:15, 9 November 2016
• Langley 2019 Biochim Biophys Acta Mol Basis Dis
  ...tress, mitochondrial dysfunction, and oxidative stress pathways in HFD-fed mouse spinal cords were also identified. Moreover, deficits in TCA cycle intermed |organism=Mouse
  3 KB (372 words) - 11:20, 3 March 2020
• Inigo 2019 Mol Metab
  ...ntribute to the metabolic regulation of skeletal muscle. However, previous mouse models utilized to assess the necessity of ERα signaling in skeletal muscl A novel mouse model was developed allowing for induced deletion of ERα in adult female s
  3 KB (508 words) - 02:28, 1 March 2020
• Hildyard 2003 Biochem J
  ...41.9 kDa MCF member with homologous proteins present in both the human and mouse genomes.
  1 KB (138 words) - 17:17, 16 January 2021
• Figueira 2021 Arch Biochem Biophys
  ...NT gene (Nnt^-/-). Further comparisons between SMM from both Nnt mouse genotypes revealed that the NADPH supplied by NNT supports up to 600 pmol/m |organism=Mouse
  3 KB (434 words) - 17:42, 18 August 2021

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