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• Sies 2019 Stress: Physiology, Biochemistry, and Pathology. Handbook of Stress Series.
  ...homeostasis. Stress: Physiology, Biochemistry, and Pathology. Handbook of Stress Series. 3:153-163. doi.org/10.1016/B978-0-12-813146-6.00013-8 |journal=Stress: Physiology, Biochemistry, and Pathology. Handbook of Stress Series.
  478 bytes (64 words) - 14:17, 4 February 2022
• Oxidative stress
  ...in pro-oxidants, by a depletion of antioxidant systems or both. Oxidative stress generates oxidative damage of proteins, lipids and DNA.
  401 bytes (54 words) - 13:26, 8 November 2016
• Neurobiol Stress
  ...=[https://www.journals.elsevier.com/neurobiology-of-stress Neurobiology of Stress]
  101 bytes (11 words) - 12:05, 13 January 2020
• MiP2013 Stress: Hypoxia
  {{#ask:[[Category:Abstracts]] [[Additional label::MiP2013]] [[Stress::Hypoxia]]
  458 bytes (63 words) - 14:48, 29 November 2016
• Salvi 2019 Neurobiol Stress
  ...mechanisms in air pollution-related neurobiological impairments. Neurobiol Stress 12:100205. |journal=Neurobiol Stress
  2 KB (219 words) - 12:31, 13 January 2020
• Sies 1985 Oxidative Stress
  ...985) Oxidative stress: introductory remarks. In: Sies H. editor. Oxidative stress. Academic Press; London 1–8.
  309 bytes (37 words) - 11:45, 22 March 2021
• Grasso 2020 Cell Stress
  ...Capelôa T, Van de Velde JA, Sonveaux P (2020) Mitochondria in cancer. Cell Stress 4:114-46. https://doi.org/10.15698/cst2020.06.221 |journal=Cell Stress
  2 KB (229 words) - 22:55, 12 October 2023
• O2k-Publications: RONS; Oxidative stress
  ...[[Instrument and method::Oxygraph-2k]] [[Injury and adaptation::Oxidative stress;RONS]] == O2k-Publications: Oxidative stress;RONS - Abstracts ==
  1 KB (191 words) - 16:11, 4 June 2017
• Jones 1985 Oxidative stress. Academic Press Inc (London) Ltd
  ...concentration in oxidative stress: hypoxic and hyperoxic models. Oxidative stress. Academic Press Inc (London) Ltd. 0-12-642760-7:151-195. ...&oi=fnd&pg=PA151&dq=Jones+PD+the+role+of+oxygen+concentration+in+oxidative+stress:+hypoxic+and+hyperoxic+models&ots=hlX8eUnw_F&sig=2CjSfBnj5051Jj1nEMamj4kGeS
  656 bytes (100 words) - 17:07, 3 February 2022
• 6th International Conference on Tumor Microenvironment and Cellular Stress 2019 Crete GR
  ...23-28. 6th International Conference on Tumor Microenvironment and Cellular Stress: Signaling, Metabolism, Imaging and Therapeutic Targets. |abstract=6th International Conference on Tumor Microenvironment and Cellular Stress: Signaling, Metabolism, Imaging and Therapeutic Targets, Chania, Crete, Gre
  1 KB (160 words) - 09:11, 8 October 2019

Page text matches

• Sies 2019 Stress: Physiology, Biochemistry, and Pathology. Handbook of Stress Series.
  ...homeostasis. Stress: Physiology, Biochemistry, and Pathology. Handbook of Stress Series. 3:153-163. doi.org/10.1016/B978-0-12-813146-6.00013-8 |journal=Stress: Physiology, Biochemistry, and Pathology. Handbook of Stress Series.
  478 bytes (64 words) - 14:17, 4 February 2022
• Latent mitochondrial dysfunction
  ...in response to a particular (e.g. oxidative) stress, using a mitochondrial stress resistance test.
  794 bytes (104 words) - 16:32, 4 October 2011
• Jones 1985 Oxidative stress. Academic Press Inc (London) Ltd
  ...concentration in oxidative stress: hypoxic and hyperoxic models. Oxidative stress. Academic Press Inc (London) Ltd. 0-12-642760-7:151-195. ...&oi=fnd&pg=PA151&dq=Jones+PD+the+role+of+oxygen+concentration+in+oxidative+stress:+hypoxic+and+hyperoxic+models&ots=hlX8eUnw_F&sig=2CjSfBnj5051Jj1nEMamj4kGeS
  656 bytes (100 words) - 17:07, 3 February 2022
• Oliveira 2018 Front Physiol
  ...França TFA, Moreira DC, Hermes-Lima M (2018) Is "Preparation for Oxidative Stress" a Case of Physiological Conditioning Hormesis?. Front Physiol 9:945. |keywords=antioxidant, biochemical adaptation, estivation, hypoxia, oxidative stress, reactive oxygen species, redox
  595 bytes (76 words) - 13:20, 31 May 2019
• Kim 2024 J Exerc Rehabil
  ...m SH (2024) Exercise before pregnancy exerts protective effect on prenatal stress-induced impairment of memory, neurogenesis, and mitochondrial function in o ...e, exercise before pregnancy may have a protective effect against prenatal stress of the offspring.
  2 KB (317 words) - 16:34, 3 April 2024
• Breitenbach 2016 Biomolecules
  |title=Breitenbach M, Eckl P (Ed.) (2016) Oxidative stress in health and disease. Biomolecules p512. |abstract=Oxidative stress is now a well-researched area with thousands of new articles
  896 bytes (128 words) - 14:15, 26 March 2018
• Hijazi 2020 J Cell Sci
  ...signaling mediates an adaptive survival response to endoplasmic reticulum stress. J Cell Sci 133:jcs241539. ...oping therapeutic strategies to limit cell death in disorders linked to ER stress.
  2 KB (257 words) - 15:53, 7 May 2020
• Azzi 2022 Antioxidants (Basel)
  |title=Azzi A (2022) Oxidative stress: What is it? Can it be measured? Where is it located? Can it be good or bad ...sign. There is no officially approved therapy to prevent or cure oxidative stress or oxidative damage.
  2 KB (241 words) - 09:24, 1 May 2024
• Ma 2020 Oxid Med Cell Longev
  |title=Ma WX, Li CY, Tao R, Wang XP, Yan LJ (2020) Reductive stress-induced mitochondrial dysfunction and cardiomyopathy. Oxid Med Cell Longev ...vide novel insights into therapeutic approaches for ameliorating reductive stress-induced cardiomyopathy.
  2 KB (217 words) - 16:11, 3 February 2022
• Salvi 2019 Neurobiol Stress
  ...mechanisms in air pollution-related neurobiological impairments. Neurobiol Stress 12:100205. |journal=Neurobiol Stress
  2 KB (219 words) - 12:31, 13 January 2020
• Sharma 2023 Biosci Biotechnol Biochem
  ...023) Valine improves mitochondrial function and protects against oxidative stress. https://doi.org/10.1093/bbb/zbad169 ...tion thereby preventing mitochondrial/cellular damage induced by oxidative stress.
  2 KB (268 words) - 15:21, 20 December 2023
• Neurobiol Stress
  ...=[https://www.journals.elsevier.com/neurobiology-of-stress Neurobiology of Stress]
  101 bytes (11 words) - 12:05, 13 January 2020
• Pignatelli 2018 Kardiol Pol
  |title=Pignatelli P, Menichelli D, Pastori D, Violi F (2018) Oxidative stress and cardiovascular disease: new insights. Kardiol Pol 76:713-722. ...cardiovascular risk, and 3) therapeutic implications to modulate oxidative stress.
  1 KB (170 words) - 09:30, 14 December 2021
• Wang 2021 Oxid Med Cell Longev
  ...etal muscle, in order to clarify the effects of exercise-induced oxidative stress on the pathophysiological functions of skeletal muscle. |injuries=Oxidative stress;RONS, Hypoxia
  2 KB (229 words) - 14:24, 4 February 2022
• Yan 2014 J Diabetes Res
  ...Pathogenesis of chronic hyperglycemia: from reductive stress to oxidative stress. J Diabetes Res 2014:137919. https://doi.org/10.1155/2014/137919 ...llular oxidative stress. Therefore, reductive stress followed by oxidative stress comprises a major mechanism of hyperglycemia-induced metabolic syndrome.
  2 KB (256 words) - 06:12, 11 October 2023
• Rains 2011 Free Radic Biol Med
  |title=Rains JL, Jain SK (2011) Oxidative stress, insulin signaling, and diabetes. Free Radic Biol Med 50:567-75. ...view outlines various mechanisms that lead to the development of oxidative stress. Intervention and therapy that alter or disrupt these mechanisms may serve
  2 KB (227 words) - 09:30, 14 December 2021
• Oxidative stress
  ...in pro-oxidants, by a depletion of antioxidant systems or both. Oxidative stress generates oxidative damage of proteins, lipids and DNA.
  401 bytes (54 words) - 13:26, 8 November 2016
• Sies 1985 Oxidative Stress
  ...985) Oxidative stress: introductory remarks. In: Sies H. editor. Oxidative stress. Academic Press; London 1–8.
  309 bytes (37 words) - 11:45, 22 March 2021
• Xiao 2020 Antioxid Redox Signal
  |title=Xiao W, Loscalzo J (2020) Metabolic responses to reductive stress. Antioxid Redox Signal 32:1330-47. DOI: 10.1089/ars.2019.7803 ...loping strategies (e.g., antireductant approaches) to counteract reductive stress and its related adverse biological consequences also requires extensive fut
  2 KB (269 words) - 17:10, 3 February 2022
• Di 2011 EMBO J
  ...n K, Mironov A, Kotiadis VN, Gourlay CW, Jones N, Wilkinson CR (2011) H₂O₂ stress-specific regulation of S. pombe MAPK Sty1 by mitochondrial protein phosphat ...PK signalling is controlled and providing an explanation for the oxidative stress-specific nature of the regulation of Sty1 by Ptc4.
  2 KB (274 words) - 16:28, 23 February 2015
• Robertson 2023 Abstract IOC160
  ...y how specific metabolic pathways are impacted in response to pathological stress and ultimately develop novel therapeutics designed to enhance mitochondrial
  2 KB (268 words) - 12:31, 6 June 2023
• Picard 2018 Psychosom Med
  |title=Picard M, McEwen BS (2018) Psychological stress and mitochondria: a systematic review. Psychosom Med 80:141-53. https://doi ...This article provides a systematic review of the effects of psychological stress on mitochondrial structure and function.
  2 KB (306 words) - 00:07, 13 September 2023
• Furlanetto 2014 Thesis University of Parana
  ...ited in both, 24h and 48h of stress. The cold stress induces the oxidative stress in embryogenic ''A. angustifolia'' cells, which result in up-regulation of ...ds=''Araucaria angustifolia'', Embryogenic cells, Plant mitochondria, Cold stress, Antioxidant enzymes
  3 KB (428 words) - 10:15, 9 November 2016
• Gak 2015 Biochim Biophys Acta
  ...vic SM, Dukic AR, Janjic MM, Stojkov-Mimic NJ, Kostic TS, Andric SA (2015) Stress triggers mitochondrial biogenesis to preserve steroidogenesis in Leydig cel ...anticipate our result to be a starting point for more investigations since stress is a constant factor in life and has become one of the most significant hea
  2 KB (338 words) - 10:38, 22 March 2016
• Li 2015 Oxid Med Cell Longev
  ...Bo H, Li J, Zhang Y and Ji LL (2015) Acute Exercise-Induced Mitochondrial Stress Triggers an Inflammatory Response in the Myocardium via NLRP3 Inflammasome ...aken together, our data suggest that, during acute exercise, mitochondrial stress triggers the rat myocardial inflammatory response via NLRP3 inflammasome ac
  2 KB (279 words) - 09:16, 8 November 2016
• Hoek 2002 Gastroenterology
  ...epaired, impairs mitochondrial function, which further increases oxidative stress in the cell, leading to a vicious cycle of accumulating cell damage that is |injuries=Oxidative stress;RONS
  2 KB (305 words) - 11:14, 12 July 2023
• Moisoi 2018 MiP2018a
  ...of the initiating stress, mitochondria or the nucleus can take the lead in stress response initiation - ‘talks first’. In most situations the nucleus and
  2 KB (222 words) - 08:09, 13 September 2018
• Silber Ariel Mariano
  ...metabolism, amino acid metabolism, parasitology, redox stress, nutritional stress
  726 bytes (93 words) - 10:59, 15 February 2022
• UK Cambridge Martins LM
  |keyword=Stress, Parkinson's Disease, Apoptosis, Mitochondrial Signalling |keywords=Stress; parkinson's disease; apoptosis
  736 bytes (96 words) - 13:50, 15 September 2021
• Gumpp 2020 Mitochondrion
  ...Kolassa IT (2020) Mitochondrial bioenergetics in leukocytes and oxidative stress in blood serum of mild to moderately depressed women. Mitochondrion 58:14-2 ...ressed women. Alterations in mitochondrial energy production and oxidative stress did not linearly depend on the current severity of MDD. However, biological
  1 KB (196 words) - 15:47, 19 October 2021
• US CO Fort Collins Hamilton K
  ...aging, mitochondrial biogenesis, proteostasis, oxidative stress, energetic stress, comparative models, rapamycin, metformin, skeletal and cardiac muscle
  676 bytes (89 words) - 19:05, 20 November 2018
• Sies 1991 Am J Med
  |title=Sies H (1991) Oxidative stress: from basic research to clinical application. Am J Med 91:31-38. ...or of the pro-oxidants. A number of diseases are associated with oxidative stress, being the basis of antioxidant therapy. Current evidence in clinical resea
  972 bytes (133 words) - 11:48, 22 March 2021
• Duvigneau 2010 Shock
  ...usion does not induce oxidative stress but sustained endoplasmic reticulum stress in livers of rats subjected to traumatic/hemorrhagic shock. Shock 33:289-98 ...f the liver, independent of oxidative or nitrosylative stress. Although ER stress was not associated with depressed hepatocyte function, it may act as an ear
  3 KB (398 words) - 08:31, 16 June 2015
• Brodnanova 2021 Eur J Pharmacol
  ...imipramine on thapsigargin- and tunicamycin-induced endoplasmic reticulum stress and mitochondrial dysfunction in neuroblastoma SH-SY5Y cells. Eur J Pharmac ...ER stress and mitochondrial dysfunction in neuroblastoma SH-SY5Y cells. ER stress in SH-SY5Y cells was induced by either tunicamycin or thapsigargin in the p
  2 KB (333 words) - 16:01, 21 July 2021
• US CO Fort Collins Miller BF
  ...aging, mitochondrial biogenesis, proteostasis, oxidative stress, energetic stress, comparative models, rapamycin, metformin, skeletal and cardiac muscle
  720 bytes (92 words) - 02:44, 1 March 2023
• Erikstein 2010 J Cell Biochem
  ...kolaisen J, Kulawiec M, Singh KK, Gjertsen BT, Tronstad KJ (2010) Cellular stress induced by resazurin leads to autophagy and cell death via production of re ...phagy, and cell degradation. The ability of cells to tolerate this type of stress may be important in toxicity and chemoresistance.
  2 KB (323 words) - 18:21, 31 January 2020
• Ohsawa 2007 Nat Med
  ...gas markedly suppressed brain injury by buffering the effects of oxidative stress. Thus H₂ can be used as an effective antioxidant therapy; owing |injuries=Ischemia-reperfusion, Oxidative stress;RONS
  2 KB (251 words) - 18:19, 24 December 2021
• Saura-Esteller 2021 Int J Mol Sci
  ...Serret D, Gil J (2021) Activation of the integrated stress response and ER stress protect from fluorizoline-induced apoptosis in HEK293T and U2OS cell lines. ...t fluorizoline causes increased ER stress and activation of the integrated stress response, which in HEK293T and U2OS cells are protective against fluorizoli
  2 KB (316 words) - 12:00, 27 March 2023
• Kennedy 2017 Skelet Muscle
  ...Guiraud S (2017) Utrophin influences mitochondrial pathology and oxidative stress in dystrophic muscle. Skelet Muscle 7:22. ...sess whether utrophin could attenuate mitochondria pathology and oxidative stress.
  2 KB (298 words) - 12:05, 15 January 2018
• Mohsin 2020 Arch Biochem Biophys
  ...on J, Hu Y, Hollander J, Lesnefsky EJ, Chen Q (2020) Endoplasmic reticulum stress-induced complex I defect: Central role of calcium overload. Arch Biochem Bi ...ndent calpains. The contribution of mitochondrial calpain activation in ER stress-mediated complex I damage was studied.
  3 KB (407 words) - 08:40, 7 October 2020
• Arya 2011 Diabetes Res Clin Pract
  |title=Arya AK, Pokharia D, Tripathi K (2011) Relationship between oxidative stress and apoptotic markers in lymphocytes of diabetic patients with chronic non ...sent study was undertaken to investigate the correlation between oxidative stress and apoptotic markers in lymphocytes of diabetic patients with chronic non
  2 KB (279 words) - 15:24, 1 December 2015
• Picard 2018 Biol Psychiatry
  ...el ES (2018) A mitochondrial health index sensitive to mood and caregiving stress. Biol Psychiatry 84:9-17. https://doi.org/10.1016/j.biopsych.2018.01.012 ...y, but the underlying cellular mechanisms are not well understood. Chronic stress may induce recalibrations in mitochondria leading to changes either in mito
  2 KB (340 words) - 00:09, 13 September 2023
• Crane 2013 PLoS One
  ...l LG, Steinberg GR, Tarnopolsky MA (2013) Elevated mitochondrial oxidative stress impairs metabolic adaptations to exercise in skeletal muscle. PLoS One 8:e8 ...e results demonstrate that chronic skeletal muscle mitochondrial oxidative stress does not impact exercise induced mitochondrial biogenesis, but impairs the
  2 KB (250 words) - 16:07, 7 November 2016
• O2k-Publications: RONS; Oxidative stress
  ...[[Instrument and method::Oxygraph-2k]] [[Injury and adaptation::Oxidative stress;RONS]] == O2k-Publications: Oxidative stress;RONS - Abstracts ==
  1 KB (191 words) - 16:11, 4 June 2017
• Nakashima 2017 Free Radic Biol Med
  |title=Nakashima Y, Ohta S, Wolf AM (2017) Blue light-induced oxidative stress in live skin. Free Radic Biol Med 108:300-10. doi: 10.1016/j.freeradbiomed. ...reen, red, far red or infrared light did not. Blue light-induced oxidative stress was also detected in cultured human keratinocytes, but the per photon effic
  2 KB (240 words) - 17:56, 24 December 2021
• MiPschool Greenville 2015 Abstracts in the MiPMap
  == MiPMap - Areas: stress, diseases == |?Stress
  1 KB (130 words) - 15:56, 11 September 2014
• MiP2015 Abstracts in the MiPMap
  == MiPMap - Areas: stress, diseases == |?Stress
  1 KB (156 words) - 17:11, 8 June 2015
• Nold 2019 Psychoneuroendocrinology
  ...mitochondrial respiration to face allostatic load in a double-hit model of stress. Psychoneuroendocrinology 107:148-59. ...cortex and hippocampus, while only rats with the double-hit of adolescent stress and uCMS demonstrated increased mitochondrial activity in the hippocampus.
  3 KB (366 words) - 12:21, 9 July 2019
• Escribano-Lopez 2019 Cell Physiol Biochem
  ...tioxidant MitoQ Modulates Mitochondrial Function and Endoplasmic Reticulum Stress in Pancreatic β Cells Exposed to Hyperglycaemia.. Cell Physiol Biochem 52( ...f MitoQ on insulin secretion, oxidative stress, endoplasmic reticulum (ER) stress and nuclear factor kappa B (NFκB) signalling in a pancreatic β cell line
  3 KB (360 words) - 16:53, 3 June 2019
• MiPschool Cape Town 2015 Abstracts in the MiPMap
  == MiPMap - Areas: stress, diseases == |?Stress
  1 KB (133 words) - 15:59, 11 September 2014
• Liguori 2018 Clin Interv Aging
  ...D, Gargiulo G, Testa G, Cacciatore F, Bonaduce D, Abete P (2018) Oxidative stress, aging, and diseases. Clin Interv Aging 757–772. ...ng on a specific therapeutic target. Given the important role of oxidative stress in the pathogenesis of many clinical conditions and aging, antioxidant ther
  2 KB (290 words) - 09:29, 14 December 2021
• De Mello 2018 Life Sci
  ...in obesity, including related alterations, such as inflammation, oxidative stress, and apoptosis, and focusing on the whole organism, covering alterations in |injuries=Oxidative stress;RONS
  2 KB (267 words) - 03:31, 24 August 2021
• MiP2014 Abstracts in the MiPMap
  == MiPMap - Areas: stress, diseases == |?Stress
  1 KB (164 words) - 14:50, 29 November 2016
• Dutta 2013 Autophagy
  ...urgh C (2013) Upregulated autophagy protects cardiomyocytes from oxidative stress-induced toxicity. Autophagy 9:328-44. ...in could be utilized as a potential therapeutic strategy against oxidative stress-mediated damage in cardiomyocytes.
  3 KB (361 words) - 17:22, 23 February 2020
• Banday 2020 J Am Heart Assoc
  ...imal models. Here we show the nexus between high salt intake and oxidative stress causing renal tubular dopamine oxidation, which leads to mitochondrial and ...act on organelle function or inflammation. Resveratrol prevented oxidative stress, dopamine oxidation, organelle dysfunction, inflammation, and hypertension
  2 KB (335 words) - 09:02, 27 January 2020
• Timon-Gomez 2014 Abstract MiP2014
  ...ochondrial pyruvate carriers in the adaptation of respiration capacity and stress tolerance in yeast. ...itochondrial adaptation to different respiration rates, oxidative and salt stress.
  3 KB (377 words) - 16:42, 11 February 2015
• Weger 2020 Sci Rep
  ...nature in the prefrontal cortex for differential susceptibility to chronic stress. Sci Rep 10:18308. ...individuals with high behavioral susceptibility and resilience to chronic stress.
  2 KB (311 words) - 17:34, 4 November 2020
• Miranda Mendonca 2019 Neurochem Int
  ...F, da Silva Fragoso VM (2019) Highly aggressive behavior induced by social stress is associated to reduced cytochrome c oxidase activity in mice brain cortex ...cytochrome c oxidase. Therefore, aggressive behavior generated upon social stress associates to selective reduction in cytochrome c oxidase activity, with po
  2 KB (323 words) - 14:28, 17 April 2019
• Jelenik 2018 Mol Metab
  ...TR (2018) FGF21 regulates insulin sensitivity following long-term chronic stress. Mol Metab 16:126-38. ...mechanisms are unclear. We investigated how early-life exposure to chronic stress affects long-term insulin sensitivity.
  2 KB (312 words) - 13:26, 7 March 2020
• Wang 2017 Mol Cell
  ...uwerx J (2017) Systems phytohormone responses to mitochondrial proteotoxic stress. Mol Cell 68:540-51. ...dopsis through chemical or genetic interference. Mitochondrial proteotoxic stress activated a plant-specific UPR^mt and impaired plant growth and d
  2 KB (227 words) - 16:48, 8 January 2018
• De Punder 2022 Abstract Bioblast
  ...ens DS, Heim C, Entringer S (2022) Early life stress and perceived chronic stress are associated with increased immune cell mitochondrial DNA copy number in ...ges in PBMC mtDNAcn reflect an adaptation of mitochondria to psychological stress.
  3 KB (455 words) - 08:51, 28 July 2022
• Bullon 2015 Pharmacol Res
  .... In our experiments, LPS-treated fibroblasts provoked increased oxidative stress, mitochondrial dysfunction, reduced oxygen consumption and mitochondrial bi |injuries=Oxidative stress;RONS
  2 KB (208 words) - 15:27, 9 November 2016
• Vanasco 2008 Free Radic Res
  |title=Vanasco V, Cimolai MC, Evelson P, Alvarez S (2008) The oxidative stress and the mitochondrial dysfunction caused by endotoxemia are prevented by al ...in the heart of septic rats. The treatment with LA prevented the oxidative stress and mitochondrial dysfunction observed in this model.
  1 KB (213 words) - 11:38, 18 April 2021
• Andziak 2006 Aging Cell
  ...at the pronounced longevity of naked mole-rats is independent of oxidative stress parameters. |injuries=Oxidative stress;RONS
  2 KB (304 words) - 14:15, 20 February 2015
• Gaur 2021 Int J Biometeorol
  ...review highlights the interconnection between high altitude and oxidative stress and the role of anti-oxidants to protect cells from oxidative damages and t
  2 KB (296 words) - 16:30, 3 February 2022
• Foo 2022 Trends Microbiol
  ...oo J, Bellot G, Pervaiz S, Alonso S (2022) Mitochondria-mediated oxidative stress during viral infection. Trends Microbiol 30:679-92. https://doi.org/10.1016 ...sms employed by viruses to interact with mitochondria and induce oxidative stress. Furthermore, we discuss how viruses benefit from increased ROS levels, how
  1 KB (180 words) - 12:52, 8 October 2023
• Sabogal-Guaqueta 2019 Biomed Pharmacother
  ...Oun A, Kortholt A, Boddeke E, Dolga A (2019) Linalool attenuates oxidative stress and mitochondrial dysfunction mediated by glutamate and NMDA toxicity. Biom ...therapeutic agent against neurodegenerative brain diseases where oxidative stress contributes to the pathology of the disease.
  3 KB (337 words) - 12:55, 4 November 2019
• Salvi 2016 Oxid Med Cell Longev
  ...conclusion, present study provides an interesting simulation of oxidative stress in hippocampal cells, which will serve as an excellent model to study mitoc |keywords=Tempol, Buthionine sulfoximine, Oxidative stress, Mitochondria, Mouse hippocampal HT22 cells
  2 KB (284 words) - 15:06, 9 November 2016
• Schneeberger 2015 Cell Rep
  ...orzano A, Gomis R, Claret M (2015) Reduced α-MSH Underlies Hypothalamic ER-Stress-Induced Hepatic Gluconeogenesis. Cell Rep 12(3):361-70. ...s a fundamental mediator of enhanced GNG in the context of hypothalamic ER stress and establish α-MSH deficiency in proopiomelanocortin (POMC) neurons as a
  2 KB (248 words) - 17:25, 29 November 2016
• Singh 2015 Biochim Biophys Acta
  ...r J, Bonifacio A, Piquard F, Krähenbühl S, Geny B, Zoll J (2015) Reductive stress impairs myoblasts mitochondrial function and triggers mitochondrial hormesi ...he redox-dependant pathways linked to mitochondria, showing that reductive stress could trigger mitochondrial hormesis phenomenon.
  3 KB (355 words) - 20:26, 7 March 2020
• Fessler 2020 Nature
  ...schka H, Jae LT (2020) A pathway coordinated by DELE1 relays mitochondrial stress to the cytosol. Nature 579:433-437. ...issing pathway that is triggered by mitochondrial stress. Mechanistically, stress-induced activation of OMA1 causes DELE1 to be cleaved into a short form tha
  2 KB (303 words) - 09:07, 16 August 2021
• Noh 2013 Cell Death Dis
  ...Ellisman MH, Weinreb RN, Perkins GA, Ju W-K (2013) Inhibition of oxidative stress by coenzyme Q10 increases mitochondrial mass and improves bioenergetic func ...potentials and strategies for protecting ONH astrocytes against oxidative stress-mediated mitochondrial dysfunction or alteration in glaucoma and other opti
  3 KB (396 words) - 22:37, 16 February 2021
• Friederich-Persson 2012 PLoS One
  ...uncoupling via the adenine nucleotide transporter and decreases oxidative stress in diabetic kidneys. PLoS One 7:e39635. ...regulation of UCP- 2 results in excessive uncoupling and reduced oxidative stress in the kidney via activation of ANT.
  3 KB (345 words) - 16:35, 7 November 2016
• Escames 2013 Horm Mol Biol Clin Investig
  ...duction at 5 months old. Five months later, however, oxidative/nitrosative stress markers increased in both male and female mice, thus eliminating the differ |keywords=Aging, Brain, Melatonin, Mitochondria, Oxidative stress
  2 KB (328 words) - 08:05, 21 February 2020
• Sureda 2005 Free Radic Res
  ...Fuentespina E, Cordova A, Tur JA, Pons A (2005) Relation between oxidative stress markers and antioxidant endogenous defences during exhaustive exercise. Fre ...is and lymphopenia inversely correlated with cellular markers of oxidative stress. Plasma malondialdehyde (MDA) directly correlated with neutrophil MPO activ
  2 KB (273 words) - 15:11, 9 November 2016
• Schneeberger 2013 Cell
  ...ath TL, Zorzano A, Claret M (2013) Mitofusin 2 in POMC neurons connects ER stress with leptin resistance and energy imbalance. Cell 155:172-87. ...nrecognized role for MFN2 argues for a crucial involvement in mediating ER stress-induced leptin resistance.
  2 KB (277 words) - 15:57, 27 March 2018
• Bullon 2016 Periodontol 2000
  ...therosclerosis and chronic periodontitis: a shared pathology via oxidative stress and mitochondrial dysfunction? Periodontol 2000 64:139-53. ...se and diabetes lie at a fundamental intracellular level, namely oxidative stress and mitochondrial dysfunction, as a meeting background among such chronic d
  1 KB (196 words) - 09:27, 3 October 2016
• Snow 2015 PLoS One
  ...re CM, Bibby TS (2015) Quantifying integrated proteomic responses to iron stress in the globally important marine diazotroph ''Trichodesmium''. PLoS One 10. ...tic pathways as Trichodesmium reallocates the limiting resource under iron stress. ''Trichodesmium'' therefore displays a significant and integrated proteomi
  2 KB (297 words) - 15:31, 8 August 2023
• Feng 2020 Int J Biol Macromol
  ..., Shao M, Han J, Tang T, Zhang Y, Liu F (2020) TFAM, a potential oxidative stress biomarker used for monitoring environment pollutants in ''Musca domestica'' ...ts expression may serve as a useful biomarker for monitoring the oxidative stress induced by Cd, DOX or UV.
  2 KB (290 words) - 05:01, 21 November 2023
• Mastronicola 2011 IUBMB Life
  ...ucillo LP, Fiori PL, Sarti P (2011) Giardia intestinalis escapes oxidative stress by colonizing the small intestine: A molecular hypothesis. IUBMB Life 63:21 ...a greater capacity for redox buffering and a lower propensity to oxidative stress.
  2 KB (276 words) - 11:20, 21 January 2020
• Pich 2002 Free Radic Res
  ...latelet mitochondrial function of transfusional buffy coats from oxidative stress. Free Radic Res 36:429-36. ...ncing the protection of platelet mitochondrial function from the oxidative stress. The results support on one hand a possibility of protection of mitochondri
  2 KB (280 words) - 11:39, 18 April 2021
• Ost 2020 EMBO Rep
  ...es diurnal anorexia and systemic metabolic remodeling during mitochondrial stress. EMBO Rep 21:e48804. ...ts a novel diurnal action and key pathophysiological role of mitochondrial stress-induced GDF15 in the regulation of systemic energy metabolism.
  2 KB (326 words) - 12:54, 21 February 2023
• Morato 2016 Abstract IOC116
  ...nier C, Sandi C (2016) Impaired mitochondrial function mediates early life stress-induced depression. Mitochondr Physiol Network 21.11 ...findings might pave the way for the use of mitochondrial boosters to treat stress-related disorders such as depression.
  2 KB (248 words) - 19:58, 20 November 2016
• Iakovou 2022 Front Aging Neurosci
  ...Kourti M (2022) A comprehensive overview of the complex role of oxidative stress in aging, the contributing environmental stressors and emerging antioxidant ...ith the levels of prooxidant molecules. Therefore, it seems that oxidative stress plays a more complicated role than the one once believed and this role migh
  3 KB (365 words) - 00:55, 10 November 2023
• Cojocaru 2023 Antioxidants (Basel)
  ...cu R, Vlad CE, Blaj M, Foia LG (2023) Mitochondrial dysfunction, oxidative stress, and therapeutic strategies in diabetes, obesity, and cardiovascular diseas ...nally, we selected several representative biomarkers involved in oxidative stress and summarize the progress of therapeutic strategies.
  2 KB (230 words) - 15:15, 5 October 2023
• Friederich-Persson 2014 Adv Exp Med Biol
  ...ever, the Ang II effect was absent in p22(phox), suggesting that oxidative stress also modulates normal Ang II signaling. In conclusion, Ang II affects both |injuries=Oxidative stress;RONS
  2 KB (349 words) - 10:40, 9 November 2016
• Borras 2009 FEBS Lett
  ...Viña J (2009) Low ''in vivo'' brain glucose consumption and high oxidative stress in accelerated aging. FEBS Lett 583:2287-93. ...s been recently questioned. Our aim was to test whether there is oxidative stress in tissues critically involved in accelerated aging (senescence-accelerated
  1 KB (191 words) - 09:08, 14 October 2016
• Steiner 2017 Int J Biochem Cell Biol
  ...ng CH (2017) Etiology of alcoholic cardiomyopathy: Mitochondria, oxidative stress and apoptosis. Int J Biochem Cell Biol 89:125-35. https://doi.org/10.1016/j ...e activity. Recent work has also emerged linking alcohol-induced oxidative stress with apoptosis providing new insight on the codependence of these interrela
  2 KB (291 words) - 05:40, 30 October 2023
• Yuan 2022 Oxid Med Cell Longev
  |title=Yuan Q, Zeng ZL, Yang S, Li A, Zu X, Liu J (2022) Mitochondrial stress in metabolic inflammation: modest benefits and full losses. Oxid Med Cell L ...hy in the context of mitochondrial dysfunction, and moderate mitochondrial stress can have a beneficial effect. This review summarises the research progress
  1 KB (194 words) - 11:04, 22 March 2023
• Moisoi 2019 MiP2019
  |title=[[Image:MoisoiN.jpg|left|90px|Nicoletta Moisoi]] The integrated stress response mediates mitochondria-nucleus communication in neurodegeneration. ...his mechanism contributes to intracellular and intercellular signalling of stress.
  2 KB (272 words) - 12:17, 27 August 2019
• Andric 2019b MiP2019
  ...mental prerequisites for survival. Mitochondria are a key component of the stress response in all cells. For steroid-hormones-producing cells, including also ...is stimulated by cAMP-PRKA, cGMP and β-adrenergic receptors. Accordingly, stress-triggered mitochondrial biogenesis represents an adaptive mechanism and doe
  3 KB (411 words) - 14:32, 26 September 2019
• Marini 2018 Proc Natl Acad Sci U S A
  ...A, Amelio I, Willis AE, Melino G (2018) TAp73 contributes to the oxidative stress response by regulating protein synthesis. Proc Natl Acad Sci U S A 115:6219 ...s study identifies a mechanism by which TAp73 contributes to the oxidative stress response and describes a completely unexpected role for TAp73 in regulating
  2 KB (351 words) - 15:59, 25 July 2018
• Moisoi 2009 Cell Death Differ
  ...oss of HtrA2 results in the activation of a brain-specific transcriptional stress response. Cell Death Differ 16:449-64. ...We therefore propose that this brain-specific transcriptional response to stress may be important in the advance of neurodegenerative diseases.
  2 KB (307 words) - 12:23, 3 May 2022
• Evinova 2022 Mol Cell Biochem
  ...arkova Z, Brodnanova M, Dibdiakova K, Racay P (2022) Endoplasmic reticulum stress induces mitochondrial dysfunction but not mitochondrial unfolded protein re ...E1α ribonuclease with STF-083010 did not protect the SH-SY5Y cells from ER stress-induced mitochondrial dysfunction. STF-083010 itself had significant impact
  2 KB (262 words) - 13:20, 5 December 2022
• Kowaltowski 2014 Abstract MiP2014
  |abstract=Mitochondria play a key role in adapting to stress. Cardiolipin, the main anionic phospholipid in mitochondrial (mt) membranes ...ce a cardiolipin synthase-null mutant strain is unable to adapt to thermal stress, this effect is cardiolipin-dependent. Interestingly, we found that the los
  2 KB (295 words) - 12:00, 16 June 2015
• Luevano-Martinez 2015 Biochim Biophys Acta
  ...a key determinant for mtDNA stability and segregation during mitochondrial stress. Biochim Biophys Acta 1847:587-98. ...ce a cardiolipin synthase-null mutant strain is unable to adapt to thermal stress as observed by a 60% increase of cells lacking mtDNA (ρ(0)). Interestingly
  2 KB (291 words) - 12:39, 2 August 2023
• Ottolenghi 2020 Minerva Anestesiol
  ...tini G, Brizzolari A, Samaja M, Chiumello D (2020) Hyperoxia and oxidative stress in anesthesia and critical care medicine. Minerva Anestesiol 86:64-75. doi ...of key words: ("hyperoxia" OR "FiO2" OR "oxygen therapy") AND ("oxidative stress" OR "ROS" OR "RNS" OR "lipid peroxidation") AND ("anesthesia" OR "surgery"
  2 KB (338 words) - 14:19, 4 February 2022
• Kassahun 2018 DNA Repair (Amst)
  ...repair deficiency but an indirect consequence of the compensatory cellular stress response that includes MAPK activation. |keywords=Apoptosis, Base excision repair, ''C. elegans'', NTH-1, Oxidative stress
  2 KB (320 words) - 12:05, 12 February 2018
• Banh 2015 Comp Biochem Physiol B Biochem Mol Biol
  ...y fish muscle mitochondria: Potential role in acute heat-induced oxidative stress. Comp Biochem Physiol B Biochem Mol Biol 191:99-107. ...a may be, at least in part, responsible for the ROS that lead to oxidative stress in fish tissues exposed to acute heat challenge.
  3 KB (375 words) - 17:46, 8 November 2016
• Alzaid 2015 Springer
  |title=Alzaid F, Patel VB, Preedy VR (2015) Biomarkers of oxidative stress in blood. In: Preedy V, Patel V (eds) General methods in biomarker research ...tools to evaluate oxidative imbalance or indicate the degree of oxidative stress.
  2 KB (353 words) - 11:58, 9 November 2023
• Duicu 2015 Biomed Res Int
  ...Mornos C (2015) Monoamine oxidases as potential contributors to oxidative stress in diabetes: time for a study in patients undergoing heart surgery. Biomed |abstract=Oxidative stress is a pathomechanism causally linked to the progression of chronic cardiovas
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• Grasso 2020 Cell Stress
  ...Capelôa T, Van de Velde JA, Sonveaux P (2020) Mitochondria in cancer. Cell Stress 4:114-46. https://doi.org/10.15698/cst2020.06.221 |journal=Cell Stress
  2 KB (229 words) - 22:55, 12 October 2023
• Mas-Bargues 2022 Antioxidants (Basel)
  ...th are indirect approaches, provide a reliable method to measure oxidative stress on a given sample. Recently, the Seahorse XF and the Oroboros O2k systems h |keywords=ROS, In vivo imaging, Oroboros, Oxidative stress, Redox state, Seahorse
  2 KB (279 words) - 16:07, 28 November 2022
• Dobrowolski 2021 Mol Genet Metab
  ...kley J, Blair HC (2021) Mesenchymal stem cell energy deficit and oxidative stress contribute to osteopenia in the Pah^enu2 classical PKU mouse. Mol ...mpetence involves an energy deficit. We posit energy support and oxidative stress reduction will enable Pah^enu2 MSC differentiation in the osteobl
  3 KB (365 words) - 15:00, 20 October 2021
• Korge 2015 Biochim Biophys Acta
  ...ss JN (2015) Increased reactive oxygen species production during reductive stress: the roles of mitochondrial glutathione and thioredoxin reductases. Biochim ...us factors. These findings may explain how ROS production during reductive stress overwhelms ROS scavenging capability, generating the net mitochondrial ROS
  2 KB (304 words) - 17:08, 3 February 2022
• Flockhart 2023 Redox Biol
  ...en FJ (2023) Glucosinolate-rich broccoli sprouts protect against oxidative stress and improve adaptations to intense exercise training. https://doi.org/10.10 ...s and support mitochondrial function and protein integrity under oxidative stress, in both Nrf2-dependent and independent manners. We here administered gluco
  2 KB (256 words) - 18:17, 22 September 2023
• Deutschman 2019 J Cell Sci
  ...dysfunction impacts mitochondrial respiration and mitochondrial oxidative stress responses. J Cell Sci 132:jcs233783. ...rprisingly, we find that loss of NCAPD3 also sensitizes cells to oxidative stress. Together, these studies identify new, and possibly independent, roles for
  2 KB (302 words) - 15:44, 27 November 2019
• Paglialunga 2012 Diabetologia
  ...d oxidative stress; we also determined the impact of any reduced oxidative stress on muscle insulin sensitivity and mitochondrial function. ...mice, compared with mice on low-fat chow diet (LF) or HF alone. Oxidative stress was measured as protein carbonylation levels. Glucose tolerance tests, gluc
  3 KB (366 words) - 15:37, 15 June 2015
• Steffen 2023 J Exp Biol
  ...indicate possible trade-off of higher respiration. The high plasticity and stress tolerance of ''C. gigas'' mitochondria may contribute to the success of thi ..., High-resolution respirometry, Hypoxia tolerance, Mitochondria, Oxidative stress marker
  3 KB (379 words) - 18:14, 25 July 2023
• Hafen 2018 J Appl Physiol (1985)
  ...e CN, Sorensen JR, Hancock CR, Hyldahl RD (2018) Repeated exposure to heat stress induces mitochondrial adaptation in human skeletal muscle. J Appl Physiol ( ...ed in human skeletal muscle in response to repeated exposures to mild heat stress.
  2 KB (313 words) - 13:04, 17 April 2019
• Flis 2018 Oxid Med Cell Longev
  ...2018) Swim training modulates skeletal muscle energy metabolism, oxidative stress, and mitochondrial cholesterol content in amyotrophic lateral sclerosis mic ...Swim training also maintained mitochondrial function and lowered oxidative stress. These data suggest that modification of MAMs might play a crucial role in
  2 KB (306 words) - 16:32, 28 May 2018
• Johnson 2018 J Mol Cell Cardiol
  ...lar to TAZKD littermates. These findings indicate that resolving oxidative stress is not sufficient to suppress cardioskeletal myopathy associated with BTHS. |keywords=Barth syndrome, Cardiomyopathy, Mitochondria, Oxidative stress, Reactive oxygen species
  2 KB (335 words) - 02:29, 1 March 2020
• Temelie 2023 Int J Mol Sci
  ...integrated stress response and mitochondrial integrity modulate genotoxic stress impact and lower the threshold for immune signalling. https://doi.org/10.33 ...chondria quality control, namely HtrA2 loss of function, and/or integrated stress response, namely CHOP loss of function, and genotoxicity to address the dis
  3 KB (341 words) - 15:58, 17 April 2023
• Breton-Romero 2014 Biochim Biophys Acta
  ...z-Molledo M, Brandes RP, Rial E, Enríquez JA, Lamas S (2014) Laminar shear stress regulates mitochondrial dynamics, bioenergetics responses and PRX3 activati ...l cells as active players, able to transduce the mechanical force of shear stress in the vascular endothelium into a biological response.
  2 KB (304 words) - 15:56, 9 November 2016
• Schafer 2001 Free Radic Biol Med
  ...ed with cell growth and development, signaling, and reductive or oxidative stress. |injuries=Oxidative stress;RONS
  2 KB (300 words) - 12:34, 31 May 2019
• Parajuli 2012 PLoS One
  ...ath after 48 hours. These results suggested that MitoQ decreased oxidative stress, tubular damage and cell death by improving mitochondrial function during c |injuries=Ischemia-reperfusion, Oxidative stress;RONS
  2 KB (318 words) - 09:41, 8 November 2016
• Shao 2016 Cell Res
  ...together, our results suggest a neuropeptide coordination of mitochondrial stress response in the nervous system.
  1 KB (202 words) - 02:50, 1 March 2020
• Dilberger 2019 Oxid Med Cell Longev
  ...2019) Mitochondrial oxidative stress impairs energy metabolism and reduces stress resistance and longevity of ''C. elegans''. Oxid Med Cell Longev 2019:68405 Nematodes were incubated with various concentrations of paraquat in a heat-stress resistance assay (37°C) using nucleic staining. The most effective concent
  3 KB (398 words) - 15:03, 5 December 2019
• Sandri 2016 Abstract Mito Xmas Meeting Innsbruck
  ...ive stress, and profound weakness. Mitochondrial dysfunction and oxidative stress directly affect acto-myosin interaction and force generation. Inhibition of
  2 KB (248 words) - 11:54, 14 December 2016
• Garnol 2014 Physiol Res
  ...f mitochondrial function of rat hepatocytes by high fat diet and oxidative stress. Physiol Res 63:271-4. ...atocytes. Our data thus indicates that combination of HFD and peroxidative stress potentiates HFD damaging effect of mitochondria because both branches of th
  2 KB (272 words) - 14:18, 13 November 2017
• Bullon 2011 Free Radic Biol Med
  ...s in periodontal patients. Abnormal PBMC performance may promote oxidative stress and alter cytokine homeostasis. In conclusion, mitochondrial dysfunction co
  2 KB (267 words) - 15:27, 9 November 2016
• 6th International Conference on Tumor Microenvironment and Cellular Stress 2019 Crete GR
  ...23-28. 6th International Conference on Tumor Microenvironment and Cellular Stress: Signaling, Metabolism, Imaging and Therapeutic Targets. |abstract=6th International Conference on Tumor Microenvironment and Cellular Stress: Signaling, Metabolism, Imaging and Therapeutic Targets, Chania, Crete, Gre
  1 KB (160 words) - 09:11, 8 October 2019
• Boeck 2016 Mitochondrion
  ...d maltreatment: The involvement of mitochondrial alterations and oxidative stress. Mitochondrion 30:197-207. ...ciation of alterations in immune cell mitochondrial functioning, oxidative stress and the pro-inflammatory phenotype observed in individuals with a history o
  3 KB (410 words) - 13:43, 2 March 2020
• Xu 2022 Sci Adv
  |title=Xu H, Ahn B, Van Remmen H (2022) Impact of aging and oxidative stress on specific components of excitation contraction coupling in regulating for ...vide a better understanding of the specific impacts of aging and oxidative stress on mechanisms related to muscle weakness that may point to future intervent
  2 KB (272 words) - 16:02, 2 November 2022
• Starovlah 2019a MiP2019
  ...rovlah-MitoEAGLE2019.JPG|left|90px|Isidora Starovlah]] Psychophysiological stress changes transcriptional profile of molecular markers of mitochondrial dynam ...the convergent pathways. Although psychophysical stress is the most common stress in human society, the markers of mitochondrial dynamics in myocardium were
  3 KB (398 words) - 14:50, 26 September 2019
• Bombaca 2022 BEC
  ...Menna-Barreto RFS (2022) Mitochondrial plasticity in trypanosomatids as a stress adaptation mechanism. Bioenerg Commun 2022.20. https://doi.org/10.26124/bec ...cal role in bioenergetics, mitochondria contribute decisively to oxidative stress due to electron leakage from the electron transfer system. Several function
  2 KB (303 words) - 10:44, 9 January 2023
• Cassereau 2020 Exp Neurol
  ...N, Verny C, Reynier P, Bonneau D, Lenaers G, Procaccio V (2020) Oxidative stress contributes differentially to the pathophysiology of Charcot-Marie-Tooth di ...sveratrol. Together, these results suggest that the reduction of oxidative stress may constitute a promising therapeutic strategy for CMT2K.
  2 KB (322 words) - 08:22, 21 February 2020
• Bombaca 2022 MitoFit
  ...Menna-Barreto RFS (2022) Mitochondrial plasticity in trypanosomatids as a stress adaptation mechanism. https://doi.org/10.26124/mitofit:2022-0016 — ''2022 .../Bombaca_2022_MitoFit.pdf Mitochondrial plasticity in trypanosomatids as a stress adaptation mechanism]<br/>
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• Dosek 2007 Respir Physiol Neurobiol
  ...ek A, Ohno H, Acs Z, Taylor AW, Radak Z (2007) High altitude and oxidative stress. Respir Physiol Neurobiol 158:128-31. ...Therefore, special attention is necessary to curb the degree of oxidative stress.
  2 KB (214 words) - 16:28, 3 February 2022
• Temelie 2018 Oxid Med Cell Longev
  ...e same cells showed an impaired induction of bystander phenomena following stress insults. However, these cells responded adaptively when a challenge dose wa
  2 KB (328 words) - 13:55, 24 July 2018
• Pfeiffer 2017 Free Radic Biol Med
  ...Bcl-xL knockout attenuates mitochondrial respiration and causes oxidative stress that is compensated by pentose phosphate pathway activity. Free Radic Biol ...aining mitochondrial respiratory capacity. Its deficiency causes oxidative stress, which is associated with an increased glycolytic capacity and balanced by
  3 KB (365 words) - 15:42, 29 November 2017
• Ransy 2020 Int J Mol Sci
  ...A, Bouillaud F (2020) Use of H₂O₂ to cause oxidative stress, the catalase issue. Int J Mol Sci 21:9149. https://doi.org/10.3390/ijms212 ...sub>O₂) is a method commonly used to trigger cellular oxidative stress. However, the doses used (often hundreds of micromolar) are disproportional
  2 KB (252 words) - 10:13, 7 March 2024
• Sánchez-Iglesias 2009 J Neurochem
  ...nchez-Sellero I, Labandeira-García JL, Soto-Otero R (2009) Brain oxidative stress and selective behaviour of aluminium in specific areas of rat brain: potent ...luminium also enhanced the ability of 6-hydroxydopamine to cause oxidative stress and neurodegeneration in the dopaminergic system, which confirms its potent
  2 KB (297 words) - 16:53, 17 September 2018
• Sies 2017 Annu Rev Biochem
  |title=Sies H, Berndt C, Jones DP (2017) Oxidative Stress. Annu Rev Biochem 86:715-748. ...switches such as Nrf2/Keap1 or NF-κB/IκB is used for system-wide oxidative stress response. Nonradical species such as hydrogen peroxide (H2O2) or singlet mo
  2 KB (205 words) - 12:14, 22 March 2021
• Andric Silvana
  ::::** ''stress -/+ systemic or intratesticular blockade of different stress receptors (alpha1ADR; betaADR; GR)
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• Welker 2013 Comp Biochem Physiol A Mol Integr Physiol
  ...ntioxidant system - coined over a decade ago as "preparation for oxidative stress" - controls the possible harmful effects of increased ROS formation during |keywords=Hypoxia, Anoxia, Antioxidants, Lipid peroxidation, Oxidative stress, Oxygen sensing
  2 KB (349 words) - 12:24, 31 May 2019
• Lin 2006 Nature
  |title=Lin MT, Beal MF (2006) Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases. Nature 443:787-95. ...feature of neurodegeneration. Mutations in mitochondrial DNA and oxidative stress both contribute to ageing, which is the greatest risk factor for neurodegen
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• Publications: AOX
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• Publications: AmR
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• Publications: search labels
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• Kucera 2014 Oxid Med Cell Longev
  ...rvinková Z (2014) The effect of tert-butyl hydroperoxide-induced oxidative stress on lean and steatotic rat hepatocytes ''in vitro''. Oxid Med Cell Longev 20 ...tudy was designed to evaluate the effect of exogenous inducer of oxidative stress (tert-butyl hydroperoxide, tBHP) on nonfatty and steatotic hepatocytes isol
  2 KB (315 words) - 14:14, 9 November 2016
• Gvozdjakova 2020 Diagnostics (Basel)
  ...itochondrial respiration, endogenous coenzyme Q₁₀ and oxidative stress in patients with chronic kidney disease. Diagnostics (Basel) 10:176. ...disease progression. We tested whether CoQ₁₀ levels, oxidative stress and platelet mitochondrial bioenergetic function differ between groups of C
  3 KB (382 words) - 01:35, 4 November 2021
• Seo 2019 Exp Neurol
  ...y hippocampal mitochondrial function and neuroplasticity in post-traumatic stress disorder. Exp Neurol 322:113043. ...el, adenine nucleotide translocase, and cyclophilin-D. Exposure to extreme stress also decreased neuroplasticity by increasing apoptosis and decreasing the b
  3 KB (360 words) - 16:49, 9 April 2020
• Pantner 2021 Sci Rep
  ...from DJ-1 deficient (DJ-1 KO) hearts showed increased levels of glycative stress following I/R. Additionally, Complex I and Complex III glycation were found
  3 KB (387 words) - 13:49, 5 October 2021
• Harris 2019 Cell Metab
  ...to an accumulation of polyubiquitinated proteins, induction of proteotoxic stress, and cell death. These results indicate that depletion of GSH renders cance ...t shock factor 1; high-throughput screening; oxidative stress; proteotoxic stress; unfolded protein response
  2 KB (303 words) - 15:42, 31 May 2019
• Nolfi-Doneganab 2020 Redox Biol
  ...ROS), which contributes to both homeostatic signaling as well as oxidative stress during pathology. In this graphical review we provide an overview of oxidat |injuries=Oxidative stress;RONS
  1 KB (146 words) - 18:58, 12 August 2020
• Chen 2020 Chem Biol Interact
  ...n H (2020) TGF-β1 signaling protects retinal ganglion cells from oxidative stress via modulation of the HO-1/Nrf2 pathway. Chem Biol Interact 331:109249. ...e-1 (HO-1) and nuclear factor erythroid 2-related factor (Nrf2), which are stress-response proteins. ROS accumulation followed by the accumulation of hypoxia
  3 KB (379 words) - 20:46, 6 November 2020
• Polajnar 2014 Biochim Biophys Acta
  ...gates: correlation between cell death, aggregate number/size and oxidative stress. Biochim Biophys Acta 1843:2089-99. ...upon overexpression. Mutant- and oligomer-dependent increase in oxidative stress and cell death in cells bearing aggregates was shown. On the other hand, th
  2 KB (338 words) - 15:52, 27 July 2016
• Alandijany 2013 J Neurovirol
  ...uces mitochondrial dysfunction leading to ROS overgeneration and oxidative stress. |keywords=Oxidative stress, Pathogenesis, Rabies, Rabies virus, Reactive oxygen species
  3 KB (350 words) - 16:41, 16 October 2018
• Wang 2019 Free Radic Biol Med
  ...ests the protection mechanisms of Igf1r^+/- cells from oxidative stress through the activation of the mitochondrial respiratory chain and LKB1/AMPK ...ted cancer, IGF-1R, LKB1/AMPK pathways, Mitochondrial functions, Oxidative stress, Ulcerative colitis
  2 KB (341 words) - 12:04, 14 August 2019
• Perry 2002 Free Radic Biol Med
  ...ges, and we also consider other neurodegenerative diseases where oxidative stress has been implicated. Although much data remain to be collected, the broad s ...; Amyloid-β; Antioxidants; Homeostasis; Neurofibrillary tangles; Oxidative stress; Redox balance; Senile plaque; τ; Free radicals
  2 KB (224 words) - 11:30, 23 April 2015
• Heher 2022 Redox Biol
  ...nd hypoxic adaptation in facioscapulohumeral muscular dystrophy: Metabolic stress as potential therapeutic target. https://doi.org/10.1016/j.redox.2022.10225 ...Thus, FSHD myogenesis is uniquely susceptible to hypoxia-induced oxidative stress as a consequence of metabolic mis-adaptation. Importantly, mitochondria-tar
  3 KB (416 words) - 14:58, 5 December 2022
• Quiles 2006 Plant Cell Environ
  ...ld of photosystem (PS) II, indicating the close synergistic effect of both stress fac- tors on PS II inhibition and the subsequent irreversible damage to the ...up-regulation of the PTOX and the thylakoidal NADH DH complex under these stress conditions supports a role for chlororespiration in the protection against
  2 KB (321 words) - 09:38, 11 September 2021
• Andreyev 2005 Biochemistry (Mosc)
  ...mission. It is suggested that mitochondria augment intracellular oxidative stress due primarily to failure of their ROS removal systems, whereas the role of
  2 KB (233 words) - 21:38, 11 April 2022
• Herst 2017 Front Endocrinol (Lausanne)
  ...es that modulate body metabolism. Under conditions of severe mitochondrial stress, mitochondria have been shown to traffic between cells, replacing mitochond |injuries=Oxidative stress;RONS, Hypoxia
  3 KB (410 words) - 03:21, 24 August 2021
• Boardman 2019 Can J Physiol Pharmacol
  ...adaptive and maladaptive ROS in isolated rat hearts subjected to ischemic stress. Can J Physiol Pharmacol 98:139-46. ...ROS stress induced by high pressure perfusion, uric acid lowered oxidative stress and reduced infarct size. In contrast, uric acid blocked cardioprotection i
  2 KB (318 words) - 15:30, 7 May 2020
• Rodrigues 2018 Free Radic Biol Med
  ..., our results suggest a connection between sleep deprivation and oxidative stress, pointing to mitochondria as a possible target of this relationship. |keywords=Akt1, Antioxidant enzymes, Hsp83, Nrf2, Oxidative stress, Pale, Pp2a, Sleep disorders, p38β
  2 KB (277 words) - 16:51, 29 May 2018
• US TX Waco Koutakis P
  |keyword=Skeletal muscle, Oxidative stress, Peripheral Artery Disase
  342 bytes (44 words) - 16:31, 3 November 2022
• Peugnet 2022 Antioxidants (Basel)
  ...2) Mitochondrial-targeted therapies require mitophagy to prevent oxidative stress induced by SOD2 inactivation in hypertrophied cardiomyocytes. https://doi.o ...effect of MitoQ. Our data showed the importance of mitochondrial oxidative stress in the development of cardiomyocyte hypertrophy. We observed that targeting
  3 KB (351 words) - 16:44, 30 November 2022
• Vega 2006 Enzyme Microb Technol
  ...s and respiration in ''Chlamydomonas reinhardtii''. Induction of oxidative stress. Enzyme Microb Technol 40:163-7. ...NaCl concentration in the culture medium. These data indicate that abiotic stress induces in ''C. reinhardtii'' an increase of intracellular peroxide, which
  2 KB (292 words) - 15:34, 8 August 2023
• Boada 2004 Free Radical Biol Med
  ...rgy limitation in the mink lung epithelial cell line Mv1Lu. This metabolic stress reduced the ATP available in transfected cells by 20%, which downregulated |keywords=Metabolic stress, 6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase, Fructose 2,6-bisphos
  2 KB (213 words) - 17:12, 19 February 2018
• Schottlender 2021 Biomolecules
  ...perbaric oxygen treatment: effects on mitochondrial function and oxidative stress. Biomolecules 11:1827. https://doi.org/10.3390/biom11121827 ...rrent views on the effects of HBOT on mitochondrial function and oxidative stress, the interplay between them and the implications for several diseases.
  2 KB (245 words) - 00:11, 4 November 2023
• Tretter 2005 Philos Trans R Soc Lond B Biol Sci
  ...05) Alpha-ketoglutarate dehydrogenase: a target and generator of oxidative stress. Philos Trans R Soc Lond B Biol Sci 360:2335-45. ...enzyme could be critical in the metabolic deficiency induced by oxidative stress. Aconitase in the Krebs cycle is more vulnerable than alpha-KGDH to ROS but
  2 KB (231 words) - 13:47, 27 March 2018
• Airik 2023 Antioxidants (Basel)
  ...sis. Our findings indicate that therapeutic modulation of kidney oxidative stress may be a promising avenue to mitigate FAN1/KIN kidney pathophysiology and d ...N1, Chronic kidney disease, Karyomegalic interstitial nephritis, Oxidative stress
  3 KB (393 words) - 16:18, 16 May 2023
• Aral 2018 MiP2018
  ...e literature to clarify the effects of LETM1 loss in relation to oxidative stress and melatonin on mitochondrial function. |injuries=Oxidative stress;RONS
  3 KB (399 words) - 09:15, 20 August 2018
• Dannheisig 2019 Cells
  ...mitochondria and that PPAN knockdown triggers a p53-independent nucleolar stress response culminating in mitochondrial apoptosis. Here, we demonstrate a nov ...rkin, Wnt target, Apoptosis, Autophagy, Mitochondria, Mitophagy, Nucleolar stress, Nucleolus, Ribosome
  2 KB (289 words) - 13:22, 27 August 2019
• UK London Carling D
  Cellular Stress Group,
  357 bytes (49 words) - 13:57, 15 September 2021
• Verschoor 2013 Cancer Metab
  ...gene expression profile reveals associations with metabolism and oxidative stress in ovarian and breast cancers. Cancer Metab 1:17. ...ology, and network representations were visualized in Cytoscape. Oxidative stress regulation was examined in ovarian cancer cells by measuring protein expres
  3 KB (387 words) - 15:16, 9 November 2016
• Moisoi 2017 MiP2017
  ...ytoplasmic stress), DNA damage and repair signalling, as well as oxydative stress responses. The data demonstrates that PINK1 modulates these signalling path
  2 KB (288 words) - 13:22, 23 October 2017
• Agudelo 2014 Cell
  ...muscle PGC-1α1 modulates kynurenine metabolism and mediates resilience to stress-induced depression. Cell 159:33-45. ...ic PGC-1α1 transgenic mice resistant to depression induced by chronic mild stress or direct kynurenine administration. This study opens therapeutic avenues f
  2 KB (276 words) - 00:48, 13 December 2021
• Schoenfeld 2016 J Cereb Blood Flow Metab
  ...tion of b-oxidation is not a valid therapeutic tool for reducing oxidative stress in conditions of neurodegeneration. J Cereb Blood Flow Metab 37:848-54. ...ive stress in cerebral tissue. This question is important, since oxidative stress is the cause of neurodegeneration in numerous neurodegenerative or inflamma
  2 KB (298 words) - 16:23, 9 May 2017
• Van den Berg 2017 Am J Respir Crit Care Med
  ...ess are unknown, but might include mitochondrial dysfunction and oxidative stress. ...itochondrial function and structure, and by increased markers of oxidative stress.
  3 KB (379 words) - 15:37, 21 August 2019
• TR Istanbul Dogan SA
  |keyword=mitochondrial myopathy, reactive oxygen species, mitochondrial stress signaling
  407 bytes (53 words) - 11:49, 1 February 2021
• Battaglia 2020 Cell Death Dis
  ...f neuronal activity, which are linked to increased intracellular oxidative stress, and to the activation of the NF-kB/c-Abl/DRP1 axis.
  2 KB (278 words) - 17:12, 2 December 2020
• Thomas 2011 Mitochondrion
  ...s and ATP synthesis, improves motor function after MPTP, reduces oxidative stress and increases survival after endotoxin. Mitochondrion 11:108-18. ...entration-dependent reduction of methylpyridinium (MPP+)-induced oxidative stress and increases in lowered ATP levels and viability. Mice treated with weekly
  2 KB (214 words) - 15:36, 9 November 2016
• Rodriguez 2022 Abstract Bioblast
  ...N (2022) Mitonuclear interactions impact responses to metabolic and redox stress at different life stages in ''Drosophila melanogaster''. '''Bioblast 2022: ...tonuclear mismatches can lead to diverging responses to mild physiological stress, undermining fitness in some cases, but surprisingly improving outcomes in
  2 KB (295 words) - 08:49, 28 July 2022
• Alcocer-Gomez 2016 Biochim Biophys Acta
  ...m from caloric restricted mice improved the response to moderate oxidative stress and mitochondrial metabolism in FM fibroblasts. These results suggest that ...MPK, Caloric restriction, Fibromyalgia, Metformin, Mitochondria, Oxidative stress
  2 KB (325 words) - 08:14, 21 February 2020
• Hoepken 2007 Neurobiol Dis
  ...zed lymphoblasts from three patients homozygous for G309D-PINK1. Oxidative stress was evident from increases in lipid peroxidation and in antioxidant defense |keywords=Malondialdehyde, MnSOD, Glutathione, Mitochondria, Oxidative stress, PINK1, PARK6;, Fibroblasts
  2 KB (327 words) - 17:04, 19 February 2018
• Masci 2008 Biochim Biophys Acta
  ...ex IV. It is suggested that the peculiar response of AT mitochondria to NO stress may be relevant to the mitochondrial metabolism of AT patients. |keywords=Nitrosative stress, Bioenergetics, Cytochrome c oxidase, Genetic disease, Reaction mechanism,
  2 KB (292 words) - 11:20, 21 January 2020
• Starovlah 2019b MiP2019
  ..., calcium homeostasis, steroid biosynthesis, but also the key component of stress response. However, the molecular adaptation of spermatozoa from stressed ma ...pproach, epididymal spermatozoa from undisturbed rats were stimulated with stress hormones adrenaline and cortisol.
  3 KB (394 words) - 14:58, 26 September 2019
• Stefanatos 2012 Cell Cycle
  ...A, Ayala V, Jacobs HT, Pamplona R, Sanz A (2012) dj-1β regulates oxidative stress, insulin-like signaling and development in Drosophila melanogaster. Cell Cy ...this mutation. Our results reveal an important role of dj-1β in oxidative stress handling, insulin-like signaling and development in Drosophila melanogaster
  2 KB (278 words) - 15:27, 26 March 2018
• Dogan 2014 Cell Metab
  ...R, Rugarli EI, Trifunovic A (2014) Tissue-specific loss of DARS2 activates stress responses independently of respiratory chain deficiency in the heart. Cell ...respiratory chain deficiency, questioning the current view on the role of stress responses in mitochondrial diseases.
  2 KB (285 words) - 15:05, 3 February 2021
• Hernandez-Mijares 2011 Free Radic Biol Med
  ...tochondrial function. We also propose that one of the targets of oxidative stress responsible for diabetes is mitochondrial complex I. |injuries=Oxidative stress;RONS
  2 KB (289 words) - 16:10, 9 November 2016
• Ma 2015 Int J Biol Sci
  ..., Li PA, Bang JJ (2015) Silver nanoparticle exposure induced mitochondrial stress, caspase-3 activation and cell death: amelioration by sodium selenite. Int ...d activation of caspase-3. It is concluded that AgNP induces mitochondrial stress and treatment with selenite is capable of preventing the adverse effects of
  2 KB (287 words) - 14:19, 9 November 2016
• Bertero 2018 Nat Rev Cardiol
  ...ng conditions. Treatments targeting substrate utilization and/or oxidative stress in mitochondria are currently being tested in patients with heart failure a
  2 KB (264 words) - 21:53, 19 October 2023
• Brahma 2014 J Lipid Res
  ...R, Haemmerle G (2014) Fibroblast growth factor 21 is induced upon cardiac stress and alters cardiac lipid homeostasis. J Lipid Res 55:2229-41. ...ether, our results show that FGF21 expression is activated upon cardiac ER stress linked to defective lipolysis and that a persistent increase in circulating
  2 KB (342 words) - 17:01, 9 November 2017
• Volodina M
  |topics=mitochondria, oxidative stress, pregnancy disorders, fertility
  452 bytes (50 words) - 16:38, 13 June 2017
• Martins L
  Cellular Stress Group,
  377 bytes (48 words) - 12:26, 14 February 2018
• Safiedeen 2016 Antioxid Redox Signal
  ...ss talk between endoplasmic reticulum and mitochondria regulates oxidative stress and mediates microparticle-induced endothelial dysfunction. Antioxid Redox ...ochondrial reactive oxygen species (ROS). Pharmacological inhibition of ER stress and silencing of neutral sphingomyelinase with siRNA abrogated all MP-media
  3 KB (375 words) - 12:48, 4 June 2018
• Mancinelli 2016 Front Physiol
  ...e Himalayas were compared. Satellite cells were investigated for oxidative stress (oxidant production, antioxidant enzyme activity, and lipid damage), mitoch ...esent study supports the phenomenon of hypobaric-hypoxia-induced oxidative stress and its role in the impairment of the regenerative capacity of satellite ce
  2 KB (289 words) - 09:47, 29 September 2016
• Ugarteburu 2020 J Clin Med
  ...used by HACE1 mutations: alterations in autophagy, mitophagy and oxidative stress response. J Clin Med 9:E913. ...r abnormalities. However, an important increase in mitochondrial oxidative stress markers and a strong reduction in the mitophagic flux were observed, sugges
  3 KB (357 words) - 15:50, 6 April 2020
• Shinmura 2013 Oxid Med Cell Longev
  |title=Shinmura K (2013) Effects of caloric restriction on cardiac oxidative stress and mitochondrial bioenergetics: potential role of cardiac sirtuins. Oxid M ...irtuins play an essential role in the reduction of mitochondrial oxidative stress during caloric restriction. We speculate that cardiac sirtuins attenuate th
  2 KB (271 words) - 23:03, 23 April 2023
• Zelenka 2016 Oxid Med Cell Longev
  ...ce these pathologies are associated with aging, inflammation and oxidative stress, we investigated whether hyperbilirubinemia interferes with ROS homeostasis ...ated serum bilirubin is generally associated with attenuation of oxidative stress, and with better anthropometric parameters, decreased inflammatory status,
  2 KB (306 words) - 10:45, 17 August 2022
• Yu 2017 Free Radic Biol Med
  ...n end products receptor RAGE controls myocardial dysfunction and oxidative stress in high-fat fed mice by sustaining mitochondrial dynamics and autophagy-lys ...e and myocardial dysfunction in HFD mice. Attenuation of cardiac oxidative stress and maintenance of healthy mitochondria population ensuring adequate energy
  3 KB (430 words) - 17:54, 23 February 2020
• Cervinkova 2007 Altern Lab Anim
  ...ial function in isolated rat hepatocytes and mitochondria during oxidative stress. Altern Lab Anim 35:353-61. ...measurements, also confirmed the dramatic impact of tBHP-induced oxidative stress on mitochondria. Swelling was observed in isolated mitochondria exposed to
  3 KB (374 words) - 10:17, 24 March 2015
• Jardim-Messeder 2015 New Phytol
  ...source of reactive oxygen species in plants and regulates development and stress responses. New Phytol 208:776-89. ...t source of ROS in plant mitochondria and regulating plant development and stress responses.
  3 KB (370 words) - 17:19, 16 February 2021
• Reactive nitrogen species
  ...NO• plays an important role in cell signaling and in oxidative-nitrosative stress.
  334 bytes (42 words) - 15:34, 23 October 2014
• Flis 2019 Int J Mol Sci
  ...rome c oxidase and malate dehydrogenase activities, and elevates oxidative stress markers in skeletal muscle. Swim training slows the reduction in muscle str ...s=ALS, Bioenergetics, Exercise, Mitochondria, Neurodegeneration, Oxidative stress
  2 KB (350 words) - 10:20, 8 August 2019
• Vaka 2019 Am J Physiol Regul Integr Comp Physiol
  ...depletion indicate an important role of NK cells in mediating mt oxidative stress in the pathology of PE. |keywords=Natural Killer cells, Placental ischemia, Mitochondria, Oxidative stress
  3 KB (387 words) - 14:49, 15 May 2019
• Xiao 2018 Antioxid Redox Signal
  ...H) and NADP(H) pools. The concept of redox stress (oxidative and reductive stress) reflected by changes in NAD(H)/NADP(H) has increasingly gained attention. ...s to ensure their normal functions and simultaneously avoid inducing redox stress. In addition, it is essential to understand how NAD(H)- and NADP(H)-utilizi
  3 KB (389 words) - 22:55, 3 November 2023
• Maarman 2016 J Appl Physiol (1985)
  ...in protects against uric acid-induced mitochondrial dysfunction, oxidative stress, and triglyceride accumulation in C₂C₁₂ myotubes. J A ...with control, uric acid increased triglyceride content by ~237%, oxidative stress by 32%, and antioxidant capacity by 135%. Uric acid also reduced endogenous
  3 KB (363 words) - 14:36, 23 February 2021
• Rojas-Morales 2019 Free Radic Biol Med
  ...ez-Lozada LG, Pedraza-Chaverri J, Tapia E (2019) Fasting reduces oxidative stress, mitochondrial dysfunction and fibrosis induced by renal ischemia-reperfusi ...int out to fasting as a robust nutritional intervention to limit oxidative stress and mitochondrial dysfunction in early acute kidney injury and also to prom
  2 KB (255 words) - 11:28, 16 August 2019
• Wang 2018 J Nutr Biochem
  ...llow-up of muscle lipid accumulation, mitochondrial activity and oxidative stress and their relationship with impaired glucose homeostasis in high fat high f ...hese diet treatment durations, muscle mitochondrial activity and oxidative stress remained unchanged and do not seem to have a major role in the observed imp
  3 KB (414 words) - 14:13, 8 August 2019
• MiP2013 Diseases: Diabetes;Obesity
  |?Stress |?Stress
  879 bytes (116 words) - 14:49, 29 November 2016
• Marie 2018 Cell Death Dis
  ...T, Sahel JA, Lenaers G, Picaud S (2018) Light action spectrum on oxidative stress and mitochondrial damage in A2E-loaded retinal pigment epithelium cells. Ce ...ctor for age-related macular degeneration (AMD). We investigated oxidative stress markers and mitochondrial changes in A2E-loaded retinal pigment epithelium
  2 KB (360 words) - 16:12, 16 February 2022
• Serviddio 2004 Hepatology
  ...secondary biliary cirrhosis in rats by preventing mitochondrial oxidative stress. Hepatology 39:711-20.. ...1) to identify the mechanisms involved in glutathione depletion, oxidative stress, and mitochondrial impairment during biliary cirrhosis induced by chronic c
  2 KB (335 words) - 16:09, 17 October 2016
• Nabben 2011 Biochim Biophys Acta
  ...g-but did not observe any protective effect of UCP3. We examined oxidative stress by quantifying 4-hydroxynonenal protein adducts and protein carbonyls in th |keywords=UCP3, oxidative stress, ROS, skeletal muscle mitochondria, oxidative capacity, fatty acids
  2 KB (308 words) - 16:24, 27 March 2018
• Pruett 2022 Biol Sex Differ
  ...M, Romero DG, Yanes Cardozo LL (2022) Mitochondrial function and oxidative stress in white adipose tissue in a rat model of PCOS: effect of SGLT2 inhibition. ...reduces adiposity via improvement in mitochondrial function and oxidative stress in WAT in PCOS model.
  3 KB (495 words) - 13:28, 29 August 2022
• Schulz 2007 Cell Metab
  ...' life span by inducing mitochondrial respiration and increasing oxidative stress. Cell Metab 6:280-93. ...e oxygen species (ROS), induces catalase activity, and increases oxidative stress resistance and survival rates, altogether providing direct evidence for a h
  2 KB (240 words) - 10:11, 9 November 2016
• Christiansen 2015 Am J Physiol Heart Circ Physiol
  ...tochondrial oxidative phosphorylation and enhanced mitochondrial oxidative stress in feline hypertrophic cardiomyopathy. Am J Physiol Heart Circ Physiol 308: ...ation (OXPHOS) capacity was impaired with enhanced mitochondrial oxidative stress in HCM. Cardiac and skeletal muscles were obtained from nine domestic cats
  3 KB (373 words) - 17:34, 25 February 2020
• Coppin 2020 Cell Death Dis
  ...rchet N, Pigny P (2020) Galectin-3 modulates epithelial cell adaptation to stress at the ER-mitochondria interface. Cell Death Dis 11:360. ...ria, preserves the integrity of mitochondrial network and modulates the ER stress response.
  3 KB (402 words) - 16:53, 18 May 2020
• Alves 2017 Free Radic Biol Med
  ...enium complex exerts antineoplastic effects that are mediated by oxidative stress without inducing toxicity in Walker-256 tumor-bearing rats. Free Radic Biol ...uggest that RuC has antitumor activity through the modulation of oxidative stress and impairment of oxidative phosphorylation, thus promoting Walker-256 cell
  2 KB (352 words) - 14:12, 12 October 2017
• Lopez-Grueso 2014 Antioxid Redox Signal
  ...Early, but not late onset estrogen replacement therapy prevents oxidative stress and metabolic alterations caused by ovariectomy. Antioxid Redox Signal 20:2 ...e usefulness of estrogen replacement therapy (ERT) in preventing oxidative stress associated with menopause is controversial. We aimed to study if there is a
  2 KB (315 words) - 14:59, 12 October 2016
• Zhou 2020 Biomed Pharmacother
  ...These results demonstrate that the improvement of mitochondrial oxidative stress and mitochondrial dysfunction is implicated in the mechanism of DNLA-mediat ...ds=Acute liver injury, Carbon tetrachloride, Nrf2, Mitochondria, Oxidative stress
  3 KB (399 words) - 04:45, 21 November 2023
• Bottje 2019 Poult Sci
  ...ochondrial ROS occurs in broilers in pulmonary hypertension syndrome, heat stress, and in the phenotypic expression of feed efficiency. Low levels of mitocho
  2 KB (273 words) - 10:43, 6 November 2023
• Moon 2012 J Korean Med Sci
  ...unction in the liver, and this is associated with an increase in oxidative stress and inflammation. |keywords=Bisphenol A, Liver, Oxidative Stress, Inflammation, HepG2 cells
  2 KB (297 words) - 16:06, 25 November 2015
• MiP2013 Diseases: Neurodegenerative
  |?Stress |?Stress
  1 KB (170 words) - 14:53, 29 November 2016
• Dirmeier 2002 J Biol Chem
  ...on RO (2002) Exposure of yeast cells to anoxia induces transient oxidative stress. Implications for the induction of hypoxic genes. J Biol Chem 277:34773-84. ...indicate that yeast cells exposed to anoxia experience transient oxidative stress and raise the possibility that this initiates the induction of hypoxic gene
  3 KB (374 words) - 17:51, 13 April 2022
• Guachalla 2009 Aging (Albany NY)
  ...f ''Sod2'' resulted in reduced SOD2 protein levels and increased oxidative stress in aging telomere dysfunctional mice, but this did not lead to an increase |keywords=Oxidative stress, Superoxide, Telomere shortening, Aging, DNA damage, SOD2, Free radicals, S
  2 KB (332 words) - 09:00, 8 March 2020
• Muellebner 2015 Biomolecules
  ...5) Heme degradation by heme oxygenase protects mitochondria but induces ER stress via formed bilirubin. Biomolecules 5:679-701. ...m against hemin-induced toxicity. BR at slightly elevated levels induces a stress response at the ER, resulting in a decreased proliferative and metabolic ac
  3 KB (391 words) - 12:12, 8 November 2016
• Quispe 2018 Redox Biol
  ...em AF (2018) Diphenyl diselenide protects neuronal cells against oxidative stress and mitochondrial dysfunction: Involvement of the glutathione-dependent ant ...al cell line (HT22) exposed to tert-BuOOH (''in vitro'' model of oxidative stress), as well as to elucidate potential mechanisms underlying this protection.
  3 KB (353 words) - 09:06, 5 May 2020
• Pokkunuri 2020 Am J Physiol Renal Physiol
  ...hat PDI inhibition diminishes Nrf2 nuclear translocation causing oxidative stress that further triggers mitochondrial dysfunction and renal cell apoptosis. T |keywords=Apoptosis, Keap1/Nrf2, Mitochondria, Oxidative Stress, PDI
  2 KB (325 words) - 18:16, 6 November 2020
• Kar 2021 Toxicol Rep
  ...s and toxicity at higher doses are attributed to mild and strong oxidative stress, respectively. Overall, the study provides a comprehensive understanding of |injuries=Oxidative stress;RONS
  2 KB (267 words) - 13:05, 12 July 2023
• Du 2017 Evolution
  ...f previous suggestions that mitochondrial dysfunction can induce oxidative stress and thus contribute to hybrid breakdown. |keywords=Energy metabolism, Oxidative stress, Post-zygotic isolation, Speciation, Temperature, Thermal sensitivity, Ampl
  2 KB (315 words) - 13:01, 7 March 2020
• Pham 2020 Eur J Appl Physiol
  ...We investigated the effect of MitoQ and CoQ10 supplementation on oxidative stress and skeletal muscle mitochondrial ROS levels and function in healthy middle ...ass and antioxidant defences were measured in muscle samples and oxidative stress markers in urine and blood samples.
  3 KB (370 words) - 14:18, 17 January 2023
• Lagendijk 1996 J Lipid Res
  ...ed forms of coenzyme Q10 in human plasma as a possible marker of oxidative stress. J Lipid Res 37:67-75. ...10 ratio may be a sensitive and practical way to measure in vivo oxidative stress. Furthermore, this indicator is independent from plasma total cholesterol c
  2 KB (297 words) - 13:47, 24 August 2021
• Morales-Alamo 2014 Free Radic Biol Med
  ...y when performed in severe acute hypoxia. However, with training oxidative stress is reduced. Paradoxically, total plasma antioxidant capacity increases duri |injuries=Oxidative stress;RONS, Hypoxia
  2 KB (267 words) - 14:21, 4 February 2022
• Andziak 2006a Aging Cell
  ...findings strongly suggest that mechanisms other than attenuated oxidative stress explain the impressive longevity of this species. |injuries=Oxidative stress;RONS
  2 KB (311 words) - 14:56, 28 March 2018
• Nordquist 2015 J Am Soc Nephrol
  ...sport efficiency. These improvements could be related to reduced oxidative stress and account for the reduced proteinuria and tubulointerstitial damage. Thus |injuries=Oxidative stress;RONS
  2 KB (312 words) - 16:25, 27 March 2018
• Cahova 2016 Am J Physiol Gastrointest Liver Physiol
  ...Kazdova L (2016) Metformin prevents ischemia reperfusion-induced oxidative stress in the fatty liver by attenuation of reactive oxygen species formation. Am ...ormin (150 mg·kg body wt(-1)·day(-1)). Metformin treatment prevented acute stress-induced necroinflammatory reaction, reduced alanine aminotransferase and as
  3 KB (391 words) - 08:15, 21 February 2020
• Mazzoli 2019 Nutrients
  ...agnuolo MS, Cancelliere R, Gatto C, Iossa S (2019) Early hepatic oxidative stress and mitochondrial changes following western diet in middle aged rats. Nutri ...pid peroxidation and Nitro-Tyrosine content, taken as markers of oxidative stress, as well as NADPH oxidase activity, were significantly higher in HFF rats,
  3 KB (382 words) - 17:04, 11 November 2019
• Ren 2017 Front Pharmacol
  ...Zhang Y (2017) Silencing of NAC1 expression induces cancer cells oxidative stress in hypoxia and potentiates the therapeutic activity of elesclomol. Front Ph ...Our findings reveal a novel mechanism by which NAC1 facilitates oxidative stress resistance during cancer progression, and chemo-resistance in cancer therap
  2 KB (311 words) - 12:50, 26 January 2018
• Hamilton 2016 Am J Physiol Heart Circ Physiol
  ...oarginine methyl ester exacerbates mitochondrial dysfunction and oxidative stress to cause heart failure. Am J Physiol Heart Circ Physiol 310:H667-80. ...d with impaired mitochondrial respiratory function and increased oxidative stress compared with either l-NAME or AngII alone, resulting in nonischemic HF.
  3 KB (410 words) - 17:18, 7 November 2016
• NL Amsterdam Nollet E
  ...=Bio-energetics, heart failure, cardiac muscle, skeletal muscle, oxidative stress
  421 bytes (52 words) - 23:06, 4 July 2022
• Langley 2019 Biochim Biophys Acta Mol Basis Dis
  ...High fat diet consumption results in mitochondrial dysfunction, oxidative stress, and oligodendrocyte loss in the central nervous system. Biochim Biophys Ac ...s in metabolic regulators, decreased mitochondrial function, and oxidative stress contribute to a loss of myelinating cells. These studies identify HFD consu
  3 KB (372 words) - 11:20, 3 March 2020
• Pichova A
  ...and newly with mouse model – tissue or rather lysate – within the study of stress and drug, diseases influence on mitochondria in intestinal system and margi
  1 KB (176 words) - 15:40, 6 September 2022
• Shigaeva 2013 Abstract MiP2013
  ...hondrial ATP-dependent potassium channel in the adaptation of organisms to stress. Mitochondr Physiol Network 18.08. ...ium from ischemia [1], in protecting of the organism against some types of stress and adaptation to it.
  4 KB (632 words) - 11:23, 28 April 2017
• Sies 1997 Exp Physiol
  |title=Sies H (1997) Oxidative stress: oxidants and antioxidants. Exp Physiol 82:291-5. ...avour of the oxidants, potentially leading to damage, is termed 'oxidative stress'. Oxidants are formed as a normal product of aerobic metabolism but can be
  1 KB (168 words) - 13:50, 25 April 2022
• MitoScore
  == MitoScore - Evaluating Mitochondrial Stress in Health and Disease == ...latent mitochondrial dysfunction, at baseline and in response to oxidative stress. As a result, interventions (nutrition, exercise, drugs, novel treatments)
  3 KB (423 words) - 08:23, 15 June 2015
• Bouitbir 2016 Antioxid Redox Signal
  ...on the mitochondrial apoptosis pathway induced by mitochondrial oxidative stress in skeletal muscle using human muscle biopsies as well as ''in vivo'' and ' ...6 myoblasts directly demonstrated the link between mitochondrial oxidative stress following atorvastatin exposure and activation of the mitochondrial apoptos
  3 KB (391 words) - 20:26, 7 March 2020
• Zakharchenko 2013 Int J Biochem Cell Biol
  ...r respiratory chain proteins underlies short-term beneficial physiological stress in mitochondria. Int J Biochem Cell Biol 45:190-200. ...organism. It was first revealed in mitochondria after a single short-time stress episode. The burst of ROS formation was congruous with changes in SDH and K
  3 KB (415 words) - 11:55, 14 December 2015
• Cigliano 2017 Mol Neurobiol
  ...sa S (2017) Short-term fructose feeding induces inflammation and oxidative stress in the hippocampus of young and adult rats. Mol Neurobiol 55:2869-83. ...that fructose treatment induces TNF-alpha production as well as oxidative stress. In conclusion, these results suggest that unbalanced diet, rich in fructos
  3 KB (376 words) - 12:08, 26 June 2019
• Huetter 2007 Aging Cell
  ...ovbro M, Lener B, Prats C, Rabol R, Dela F, Jansen-Dürr P (2007) Oxidative stress and mitochondrial impairment can be separated from lipofuscin accumulation ...ed that mitochondrial dysfunction is a major source of increased oxidative stress in tissues with high content of mitochondria, such as muscle or brain. Howe
  2 KB (334 words) - 05:23, 8 February 2020
• US CT Storrs Kwon O
  |keyword=Aging, Free Radicals, Oxidative Stress, Vascular function, Mitochondrial-targeted antioxidant (MitoQ), Mitochondri
  452 bytes (53 words) - 15:33, 1 July 2020
• Flores-Herrera 2021 Methods Protoc
  ...ial shape, dynamics and polarity assessment in leaves subjected to diverse stress conditions. |keywords=Abiotic stress, Leaf mesophyll, Plant mitochondria
  1 KB (185 words) - 14:50, 20 March 2023
• Jaber 2020 BM Exp Neurol
  ...ochondrial respiratory chain deficiencies by respirometry: beyond the Mito Stress Test. BM Exp Neurol 328:113282. ...respiratory chain function. This article discusses limitations of the Mito Stress Test, proposes a refined protocol for comparing cell populations that requi
  2 KB (326 words) - 03:19, 24 August 2021
• De Lucas 2014 J Sports Sci
  ..., Latini A (2014) Increased platelet oxidative metabolism, blood oxidative stress and neopterin levels after ultraendurance exercise. J Sports Sci 32:22-30 ...ystemic inflammation (increased neopterin) accompanied by marked oxidative stress, likely by increasing oxidative metabolism (increased oxidative mitochondri
  3 KB (347 words) - 23:21, 29 February 2020
• Leman 2015 Int J Biochem Cell Biol
  ...Bonneau D, Reynier P, Procaccio V (2015) Assembly defects induce oxidative stress in inherited mitochondrial complex I deficiency. Int J Biochem Cell Biol 65 ...ings not only highlight the relationship between CI assembly and oxidative stress, but also show the suitability of BN-PAGE analysis in evaluating the conseq
  3 KB (380 words) - 15:32, 9 November 2016
• Anderson 2019 Acta Neuropathol
  ...D10 mice reveal a tissue-specific toxic gain-of-function and mitochondrial stress response. Acta Neuropathol 138:103-21. ...rated stress response (mtISR) through mTORC1 activation, with elevation of stress-induced transcription factors, secretion of myokines, upregulated serine an
  2 KB (317 words) - 11:32, 16 August 2019
• Fessel 2013 Am J Respir Cell Mol Biol
  ..., West JD (2013) Hyperoxia synergizes with mutant BMPR2 to cause metabolic stress, oxidant injury, and pulmonary hypertension. Am J Respir Cell Mol Biol 49:7 ...utant animals. These studies demonstrate that oxidant injury and metabolic stress contribute directly to disease development and provide further evidence for
  2 KB (328 words) - 17:25, 4 June 2017

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