Difference between revisions of "Oroboros Ecosystem Agenda 2022 Archive"
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::: [[File: | == Dec 2022 == | ||
2022 Week 49 | |||
*'''Dec- 05 Mo''' | |||
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*'''Dec- 06 Tu''' | |||
:{| | |||
| width="100" align="center" |[[File:BEC2022.15.jpg|right|150px|link=https://doi.org/10.26124/bec:2022-0015 |Dambrova 2022 BEC]] | |||
|'''What is the interaction between acylcarnitines and mitochondrial physiology?''' <br> | |||
Find out in the review from [[FAT4BRAIN]] partners. <br> | |||
* Dambrova M, Cecatto C, Vilskersts R, Liepinsh E (2022) Mitochondrial metabolites acylcarnitines: therapeutic potential and drug targets. Bioenerg Commun 2022.15. https://doi.org/10.26124/bec:2022-0015 | |||
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*'''Dec- 07 We''' | |||
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*'''Dec- 08 Th''' | |||
:{| | |||
| width="110" align="center" | [[File:PlayVideo.jpg|left|80px|O2k-Videosupport|link=O2k-Videosupport]] | |||
|''' Planning to work with the Titration-Injection microPump (TIP2k)? '''<br> | |||
Prepare your TIP2k for Instrumental O<sub>2</sub> background: <br> | |||
- »'''[https://www.youtube.com/watch?v=VV9pRcK076k O2k-Videosupport: Working with the TIP2k (instrumental O<sub>2</sub> background)]'''«<br> | |||
|} | |||
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*'''Dec- 09 Fr''' | |||
2022 Week 50 | |||
*'''Dec- 12 Mo''' | |||
:{| | |||
| width="100" align="center" |[[File:BEC2022.17.jpg|right|150px|link=https://doi.org/10.26124/bec:2022-0017 |Alencar 2022 BEC]] | |||
|'''Bionenerg Commun 2022.17''' <br> | |||
Alencar et al critically review the main metabolic features of BSF and provide a hypothesis to explain the unusual metabolic network and its biological significance for this parasite form. <br> | |||
* Alencar MB, Ramos EV, Silber AM, Zíková A, Oliveira MF (2022) The extraordinary energy metabolism of the bloodstream ''Trypanosoma brucei'' forms: a critical review and hypothesis. Bioenerg Commun 2022.17. https://doi.org/10.26124/bec:2022-0017 | |||
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*'''Dec- 13 Tu''' | |||
:::: '''»[[AlgaEurope 2022 Rome IT]]«''' Dec 13-15 | |||
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*'''Dec- 14 We''' | |||
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*'''Dec- 15 Th''' | |||
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*'''Dec- 16 Fr''' | |||
2022 Week 51 | |||
*'''Dec- 19 Mo''' | |||
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*'''Dec- 20 Tu''' | |||
:{| | |||
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]] | |||
|''' Cannot open a DatLab file?'''<br> | |||
Check for special characters in the filename as this can cause problems when opening the file. | |||
<br> | |||
- »'''[[DatLab_error_messages#DatLab_error:_Could_not_open_file|DatLab error: Could not open file]]'''«<br> | |||
- communicated by »[[Schmitt Sabine]]« and »[[Cecatto Cristiane]]« | |||
|} | |||
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*'''Dec- 21 We''' | |||
:{| | |||
| width="100" align="center" |[[File:BEC2022.14.jpg|right|150px|link=https://doi.org/10.26124/bec:2022-0014 |Ganguly 2022 BEC]] | |||
|'''Bionenerg Commun 2022.14''' <br> | |||
Because the mitochondrial Complex I inhibitor rotenone is widely used to develop experimental models of Parkinson’s disease, Gangly et al examined if rotenone is an inducer of ferroptosis. <br> | |||
* Ganguly U, Bir A, Chakrabarti S (2022) Cytotoxicity of mitochondrial Complex I inhibitor rotenone: a complex interplay of cell death pathways. Bioenerg Commun 2022.14. https://doi.org/10.26124/bec:2022-0014 | |||
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*'''Dec- 22 Th''' | |||
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*'''Dec- 23 Fr''' | |||
2022 Week 52 | |||
*'''Dec- 26 Mo''' | |||
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*'''Dec- 27 Tu''' | |||
:{| | |||
| width="100" align="center" |[[File:BEC2022.19.jpg|right|150px|link=https://doi.org/10.26124/bec:2022-0019 |Vera-Vives 2022 BEC]] | |||
|'''Bionenerg Commun 2022.19''' <br> | |||
Vera-Vives et al describe the setup of a reproducible method for constructing photosynthesis-irradiance curves based on oxygen evolution. <br> | |||
* Vera-Vives AM, Perin G, Morosinotto T (2022) High-resolution photosynthesis-irradiance curves in microalgae. Bioenerg Commun 2022.19. https://doi.org/10.26124/bec:2022-0019 | |||
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*'''Dec- 28 We''' | |||
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*'''Dec- 29 Th''' | |||
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*'''Dec- 30 Fr''' | |||
== Nov 2022 == | |||
2022 Week 44 | |||
*'''Nov- 01 Tu''' | |||
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*'''Nov- 02 We''' | |||
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*'''Nov- 03 Th''' | |||
:{| | |||
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]] | |||
|'''"This tissue [white adipose tissue] shows a persistent mitochondrial dysfunction that compromises tissue metabolic plasticity after obesity"''' <br> | |||
* Gonzalez-Franquesa A et al (2022) Remission of obesity and insulin resistance is not sufficient to restore mitochondrial homeostasis in visceral adipose tissue. [[Gonzalez-Franquesa 2022 Redox Biol|»Bioblast link«]] | |||
:from the O2k-Network »[[ES Barcelona Garcia-Roves PM]]«, »[[ES Barcelona Claret M]]« and »[[DE Cologne Trifunovic A]]« | |||
|} | |||
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*'''Nov- 04 Fr''' | |||
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*'''Nov-05 Sa''' | |||
:::: Abstract submission open for [[EUROMIT2023 Bologna IT]] | |||
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2022 Week 45 | |||
*'''Nov- 07 Mo''' | |||
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*'''Nov- 08 Tu''' | |||
:{| | |||
| width="100" align="center" | [[File:O2k-brief.png|45px|link=http://wiki.oroboros.at/index.php/O2k-brief|O2k-brief repository]] | |||
|'''MCT1 plays a role in diet-induced non-alcoholic fatty liver disease and the associated brain dysfunction.''' <br> | |||
* Hadjihambi A, Konstantinou C, Klohs J, Monsorno K, Le Guennec A, Donnelly C, Cox J, Kusumbe A, Hosford PS, Soffientini U, Lecca S, Mameli M, Jalan R, Paolicelli RC, Pellerin L (2022) Partial MCT1 invalidation protects against diet-induced non-alcoholic fatty liver disease and the associated brain dysfunction. [[Hadjihambi 2022 J Hepatol|»Bioblast link«]] | |||
:from the O2k-Network »[[CH Lausanne Place N]]« | |||
|} | |||
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*'''Nov- 09 We''' | |||
:{| | |||
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]] | |||
|'''"Monitoring the dissipative component of mitochondrial respiration, efficiency of ATP production, and mitochondrial outer membrane damage during the first 6 h of NMP [normothermic machine perfusion] predicts the clinical outcome of the transplantation."''' <br> | |||
* Meszaros AT, Hofmann J, Buch ML , Cardini B, Dunzendorfer-Matt T, Nardin F, Blumer MJ, Fodor M, Hermann M, Zelger B, Otarashvili G, Schartner M, Weissenbacher A, Oberhuber R, Resch T, Troppmair J, Öfner D, Zoller H, Tilg H, Gnaiger E, Hautz T, Schneeberger S (2022) Mitochondrial respiration during normothermic liver machine perfusion predicts clinical outcome. [[Meszaros 2022 EBioMedicine|»Bioblast link«]] | |||
:from the O2k-Network »[[AT Innsbruck Schneeberger S]]« and »[[AT Innsbruck Oroboros]]« | |||
|} | |||
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*'''Nov- 10 Th''' | |||
:{| | |||
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]] | |||
|'''"High-altitude of the mountain spa environment improved mitochondrial fitness as could be seen from improved CI-linked OXPHOS and ET capacity of platelet mitochondria of patients with post-COVID-19 syndrome"''' <br> | |||
* Gvozdjáková A, Sumbalová Z, Kucharská J, Rausová Z, Kovalčíková E, Takácsová T, Navas P, López-Lluch G, Mojto V, Palacka P (2022) Mountain spa rehabilitation improved health of patients with post-COVID-19 syndrome: pilot study. [[Gvozdjakova 2022 Environ Sci Pollut Res Int|»Bioblast link«]] | |||
:from the O2k-Network »[[SK Bratislava Sumbalova Z]]« | |||
|} | |||
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*'''Nov- 11 Fr''' | |||
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2022 Week 46 | |||
*'''Nov- 14 Mo''' - World Diabetes Day | |||
:{| | |||
| width="100" align="center" | [[File:O2k-brief.png|45px|link=http://wiki.oroboros.at/index.php/O2k-brief|O2k-brief repository]] | |||
|'''Mistimed eating, e.g., during shift-work, disrupts mitochondrial function and could contribute to type-2 diabetes mellitus''' <br> | |||
* de Goede P, Wüst RCI, Schomakers BV, Denis S, Vaz FM, Pras-Raves ML, van Weeghel M, Yi CX, Kalsbeek A, Houtkooper RH (2022) Time-restricted feeding during the inactive phase abolishes the daily rhythm in mitochondrial respiration in rat skeletal muscle. [[De Goede 2022 FASEB J|»Bioblast link«]] | |||
:from the O2k-Network »[[NL Amsterdam Wuest RC]]« | |||
|} | |||
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*'''Nov- 15 Tu''' | |||
{| | |||
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]] | |||
|'''Again not a Warburg effect - OXPHOS remodeling in high-grade prostate cancer involves mtDNA mutations and increased succinate oxidation''' <br> | |||
Reproducibility is a decisive element in the progress of knowledge. The recent study by Zhang et al (2022) fully confirmed the pattern of OXPHOS remodeling described by Schöpf et al (2020) in prostate cancer. | |||
* Schöpf Bernd, Weissensteiner Hansi, Schäfer Georg, Fazzini Federica, Charoentong Pornpimol, Naschberger Andreas, Rupp Bernhard, Fendt Liane, Bukur Valesca, Giese Irina, Sorn Patrick, Sant’Anna-Silva Ana Carolina, Iglesias-Gonzalez Javier, Sahin Ugur, Kronenberg Florian, Gnaiger Erich, Klocker Helmut (2020) OXPHOS remodeling in high-grade prostate cancer involves mtDNA mutations and increased succinate oxidation. [[Schoepf 2020 Nat Commun|»Bioblast link«]] | |||
* Zhang A, Gupte AA, Chatterjee S, Li S, Ayala AG, Miles BJ, Hamilton DJ (2022) Enhanced succinate oxidation with mitochondrial Complex II reactive oxygen species generation in human prostate cancer. [[Zhang 2022 Int J Mol Sci|»Bioblast link«]] | |||
|} | |||
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*'''Nov- 16 We''' | |||
:::: '''»[[AussieMit 2022 Sydney AU]]«''' Nov 16-18 | |||
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*'''Nov- 17 Th''' - World Pancreatic Cancer Day | |||
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*'''Nov- 18 Fr''' | |||
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2022 Week 47 | |||
*'''Nov- 21 Mo''' | |||
:{| | |||
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]] | |||
|'''"Our results suggest increased proton and electron leak and a decreased ETS capacity in platelets in chronic smoke-exposed animals"''' <br> | |||
* Białas AJ, Siewiera K, Watała C, Rybicka A, Grobelski B, Kośmider L, Kurek J, Miłkowska-Dymanowska J, Piotrowski WJ, Górski P (2018) Mitochondrial functioning abnormalities observed in blood platelets of chronic smoke-exposed guinea pigs – a pilot study. [[Bialas 2018 Int J Chron Obstruct Pulmon Dis|»Bioblast link«]] | |||
:from the O2k-Network »[[PL Lodz Watala C]]« | |||
|} | |||
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*'''Nov- 22 Tu''' | |||
:{| | |||
| width="100" align="center" |[[Image:Oxia.png|150px|right|Oxia - from HyperOxia to HypOxia]] | |||
|'''Oroboros Instruments supported by WGT-Elektronik wins Cluster Award Life Sciences 2022''' <br> | |||
* '''[[Oxia]]''' in the news: [https://www.wirtschaftszeit.at/news/standortagentur-tirol-zeichnet-tirols-innovativste-unternehmen-mit-cluster-awards-2022-ausg/ Standortagentur Tirol Cluster Awards 2022] | |||
* We thank our mechatronics partner [https://www.wgt.at/ '''WGT Elektronik'''] for a fantastic collaboration! | |||
|} | |||
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*'''Nov- 23 We''' | |||
:{| | |||
| width="100" align="center" |[[File:BEC2022.10.jpg|right|150px|link=https://doi.org/10.26124/bec:2022-0010 |Roach 2022 BEC]] | |||
|'''Chlorophyll fluorescence: Easy to measure, but not always easy to interpret.''' <br> | |||
The PAM protocol proposed by Roach (2022) helps deconvolute the various components of non-photochemical quenching in ''Chlamydomonas reinhardtii''. <br> | |||
* Roach T (2022) Chlorophyll fluorescence of ''Chlamydomonas reinhardtii'': insights into the complexities. Bioenerg Commun 2022.10 https://doi.org/10.26124/bec:2022-0010 | |||
|} | |||
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*'''Nov- 24 Th''' | |||
:{| | |||
| width="110" align="center" | [[File:BEC-logo.png|left|120px|link=https://www.bioenergetics-communications.org/index.php/bec/article/view/donnelly_2022/111|BEC 2022.12]] | |||
|[[File:Oxia terms.png|left|120px]] From the [[Bioblast 2022 |Bioblast 2022: BEC Inaugural Conference]] - a conceptual link to award-winning [[Oxia]]:<br> | |||
* Donnelly C, Schmitt S, Cecatto C, Cardoso LHD, Komlódi T, Place N, Kayser B, Gnaiger E (2022) The ABC of hypoxia – what is the norm. Bioenerg Commun 2022.12. https://doi.org/10.26124/bec:2022-0012 <br> | |||
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*'''Nov- 25 Fr''' | |||
:::: [[File:FAT4BRAIN logo.png|100px|FAT4BRAIN|link=FAT4BRAIN 4th Online ESR Workshop]] <big>»'''[[FAT4BRAIN 4th Online ESR Workshop]]'''« </big> | |||
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2022 Week 48 | |||
*'''Nov- 28 Mo''' | |||
:: [[Image:O2k-Workshops.png|60px|link=MiPNet27.10 IOC156 Ramat Gan IL]] '''[[MiPNet27.10 IOC156 Ramat Gan IL|Oroboros O2k-Workshop on high-resolution respirometry (HRR) IOC 156 Ramat Gan IL]]''' Nov 28-30 | |||
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*'''Nov- 29 Tu''' | |||
:{| | |||
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]] | |||
|'''"1 mg/L treatment [of microplastics] resulted in a decrease in hepatic mitochondrial respiration and the mitochondrial membrane potential (ΔΨ), both of which were related with suppression of the mitochondrial respiratory chain (CI, CII, CII and CIV)."''' <br> | |||
* Félix L, Carreira P, Peixoto F (2022) Effects of chronic exposure of naturally weathered microplastics on oxidative stress level, behaviour, and mitochondrial function of adult zebrafish (Danio rerio). [[Felix 2022 Chemosphere|»Bioblast link«]] | |||
: | |||
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*'''Nov- 30 We''' | |||
:{| | |||
| width="100" align="center" |[[File:BEC2022.13.jpg|right|150px|link=https://doi.org/10.26124/bec:2022-0013 |Torres-Quesada 2022 BEC]] | |||
|'''Kinases are central regulators of mitochondria and cancer drugs inhibiting kinases can target mitochondrial functions.''' <br> | |||
Read how mitochondrial bioenergetics can be used to predict cancer drug off-target effects in the recently published review. <br> | |||
* Torres-Quesada O, Strich S, Stefan E (2022) Kinase perturbations redirect mitochondrial function in cancer. BEC 2022.13. https://doi.org/10.26124/bec:2022-0013 | |||
|} | |||
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*'''Dec- 01 Th''' | |||
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*'''Dec- 02 Fr''' | |||
== Oct 2022 == | |||
2022 Week 40 | |||
*'''Oct-03 Mo''' - Breast Cancer Awareness Month | |||
:: [[Image:O2k-Workshops.png|60px|link=MiPNet27.04 IOC155 Schroecken AT]] <big>'''[[MiPNet27.04 IOC155 Schroecken AT|155th Oroboros O2k-Workshop on high-resolution respirometry (HRR)]]'''</big> Oct 3-8 | |||
:::* <span style="background-color:#00FFFF>The '''Nobel Prize in Physiology or Medicine 2022''' was awarded to '''Svante Pääbo''' "for his discoveries concerning the genomes of extinct hominins and human evolution" - https://www.nobelprize.org/</span> - See [[Paeaebo 2014 Basic Books |Neanderthal man]]. | |||
:::* Short Oral Presentation submission deadline for »[[13th Targeting Mitochondria Congress 2022 Berlin DE]]« | |||
:{| | |||
| width="100" align="center" | [[File:O2k-brief.png|45px|link=http://wiki.oroboros.at/index.php/O2k-brief|O2k-brief repository]] | |||
|'''Doxorubicin-transferrin conjugate alters mitochondrial bioenergetics in breast cancer cells''' <br> | |||
* Wigner P, Zielinski K, Labieniec-Watala M, Marczak A, Szwed M (2021) Doxorubicin-transferrin conjugate alters mitochondrial homeostasis and energy metabolism in human breast cancer cells. [[Wigner 2021 Sci Rep|»Bioblast link«]] | |||
:from the O2k-Network »[[PL Lodz Watala C]]« | |||
|} | |||
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*'''Oct-04 Tu''' | |||
:: [[Image:O2k-Workshops.png|60px|link=MiPNet27.04 IOC155 Schroecken AT]] <big>'''[[MiPNet27.04 IOC155 Schroecken AT|155th Oroboros O2k-Workshop on high-resolution respirometry (HRR)]]'''</big> Oct 3-8 | |||
:{| | |||
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]] | |||
|'''“Exposure to fat feeding during pregnancy can provide metabolic advantages in the offspring, which may explain the results of [mice weaned to regular chow] demonstrating improved mitochondrial respiratory function and efficiency in the presence of fatty acid substrates since the heart relies heavily upon efficient fatty acid oxidation to meet its energy demands.”''' <br> | |||
*Chiñas Merlin A, Gonzalez K, Mockler S, Perez Y, Jia UA, Chicco AJ, Ullevig SL, Chung E (2022) Switching to a standard chow diet at weaning improves the effects of maternal and postnatal high-fat and high-sucrose diet on cardiometabolic health in adult male mouse offspring. [[Chinas 2022 Metabolites|»Bioblast link«]] | |||
:from the O2k-Network »[[ US CO Fort Collins Chicco AJ]]« | |||
|} | |||
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*'''Oct-05 We''' | |||
:: [[Image:O2k-Workshops.png|60px|link=MiPNet27.04 IOC155 Schroecken AT]] <big>'''[[MiPNet27.04 IOC155 Schroecken AT|155th Oroboros O2k-Workshop on high-resolution respirometry (HRR)]]'''</big> Oct 3-8 | |||
:{| | |||
| width="100" align="center" |[[File:MitoFit Preprints.png|100px|link=https://wiki.oroboros.at/images/2/23/Fischer_2022_MitoFit_Fe.pdf |MitoFit pdf]] | |||
|'''“Mitochondrial Ca<sup>2+</sup> handling shapes astrocytic function and is key toward brain homeostasis.”'''<br> | |||
* Cabral-Costa JV, Kowaltowski AJ (2022) Mitochondrial Ca<sup>2+</sup> handling as a cell signaling hub: lessons from astrocyte function. https://doi.org/10.26124/mitofit:2022-0027 | |||
:from the O2k-Network »[[BR Sao Paulo Kowaltowski AJ]]« | |||
|} | |||
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*'''Oct-06 Th''' | |||
:: [[Image:O2k-Workshops.png|60px|link=MiPNet27.04 IOC155 Schroecken AT]] <big>'''[[MiPNet27.04 IOC155 Schroecken AT|155th Oroboros O2k-Workshop on high-resolution respirometry (HRR)]]'''</big> Oct 3-8 | |||
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*'''Oct-07 Fr''' | |||
:: [[Image:O2k-Workshops.png|60px|link=MiPNet27.04 IOC155 Schroecken AT]] <big>'''[[MiPNet27.04 IOC155 Schroecken AT|155th Oroboros O2k-Workshop on high-resolution respirometry (HRR)]]'''</big> Oct 3-8 | |||
:::* Poster Presentation submission deadline for »[[13th Targeting Mitochondria Congress 2022 Berlin DE]]« | |||
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*'''Oct-08 Sa''' | |||
:: [[Image:O2k-Workshops.png|60px|link=MiPNet27.04 IOC155 Schroecken AT]] <big>'''[[MiPNet27.04 IOC155 Schroecken AT|155th Oroboros O2k-Workshop on high-resolution respirometry (HRR)]]'''</big> Oct 3-8 | |||
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*'''Oct-01 Sa''' | |||
:::: Abstract submission deadline for »[[BPS2023 San Diego US]]« | |||
2022 Week 41 | |||
*'''Oct-10 Mo''' - World Mental Health Day | |||
:{| | |||
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]] | |||
|'''Positive effect of regular physical activity on mitochondrial respiration in burnout syndrome '''<br> | |||
*Brand S, Ebner K, Mikoteit T, Lejri I, Gerber M, Beck J, Holsboer-Trachsler E, Eckert A (2020) Influence of regular physical activity on mitochondrial activity and symptoms of burnout-an interventional pilot study. J Clin Med 9:E667.[[Brand 2020 J Clin Med|»Bioblast link«]] | |||
:from the O2k-Network »[[ CH Basel Eckert A]]« | |||
|} | |||
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*'''Oct-11 Tu''' | |||
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*'''Oct-12 We''' - Breast Cancer Awareness Month | |||
:{| | |||
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]] | |||
|'''"NS-linked OXPHOS and ET capacity [were] decreased after prolonged exposure to BAM15."''' <br> | |||
* Zunica ERM, Axelrod CL, Cho E, Spielmann G, Davuluri G, Alexopoulos SJ, Beretta M, Hoehn KL, Dantas WS, Stadler K, King WT, Pergola K, Irving BA, Langohr IM, Yang S, Hoppel CL, Gilmore LA, Kirwan JP (2021) Breast cancer growth and proliferation is suppressed by the mitochondrial targeted furazano[3,4-b]pyrazine BAM15. [[Zunica 2021 Cancer Metab|»Bioblast link«]] | |||
:from the O2k-Network »[[US LA Baton Rouge Noland RC]]«, »[[US LA Baton Rouge Irving BA]]« and »[[US OH Cleveland Hoppel CL]]« | |||
|} | |||
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*'''Oct-13 Th''' | |||
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*'''Oct-14 Fr''' | |||
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*'''Oct-15 Sa''' | |||
:::: Registration open for [[EUROMIT2023 Bologna IT]] | |||
2022 Week 42 | |||
*'''Oct-17 Mo''' | |||
:{| | |||
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]] | |||
|'''“Chronic nitrate supplementation alone may not be a sufficient stimulus to elicit increases in muscle tissue oxygenation or respiration in [heart failure reduced ejection fraction]”''' <br> | |||
* Woessner MN, Neil C, Saner NJ, Goodman CA, McIlvenna LC, Ortiz de Zevallos J, Garnham AP, Levinger I, Allen JD (2020) Effect of inorganic nitrate on exercise capacity, mitochondria respiration and vascular function in heart failure reduced ejection fraction. [[Woessner 2020 J Appl Physiol (1985)|»Bioblast link«]] | |||
:from the O2k-Network »[[AU Melbourne Bishop DJ]]« | |||
|} | |||
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*'''Oct-18 Tu''' | |||
:{| | |||
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]] | |||
||[[File:Gnaiger 2020 BEC MitoPathways.jpg|left|70px|link=Gnaiger_2020_BEC_MitoPathways|Gnaiger 2020 BEC MitoPathways]] '''[[BEC_tutorial-Living_Communications:_pmF_to_pmP |BEC tutorial]]''': Find out the straight (yet enigmatic) connection between Gibbs energy ''G'' [J] and the 'molar Gibbs energy' of a transformation [J·mol<sup>-1</sup>], which is better called the Gibbs [[force]]:<br> | |||
::::* MitoPedia term — '''[[Gibbs energy]]''' | |||
|} | |||
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*'''Oct-19 We''' - Breast Cancer Awareness Month | |||
:{| | |||
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]] | |||
|'''"Moderate aerobic physical exercise reduces TNBC [Triple-negative breast cancer] tumoral growth with effect on tumor metabolism, characterized by a reduction in mitochondrial respiratory capacity"''' <br> | |||
* Vulczak A, Souza AO, Ferrari GD, Azzolini AECS, Pereira-da-Silva G, Alberici LC (2020) Moderate exercise modulates tumor metabolism of triple-negative breast cancer. [[Vulczak 2020 Cells|»Bioblast link«]] | |||
:from the O2k-Network »[[BR Ribeirao Preto Alberici LC]]« | |||
|} | |||
---- | |||
*'''Oct-20 Th''' | |||
:::: [[File:FAT4BRAIN logo.png|100px|FAT4BRAIN|link=FAT4BRAIN Symposium Jena DE]] <big>»'''[[FAT4BRAIN Symposium Jena DE]]'''« </big> Oct 20-21 | |||
---- | |||
*'''Oct-21 Fr''' | |||
:{| | |||
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]] | |||
||[[File:Gnaiger 2020 BEC MitoPathways.jpg|left|70px|link=Gnaiger_2020_BEC_MitoPathways|Gnaiger 2020 BEC MitoPathways]] '''[[BEC_tutorial-Living_Communications:_pmF_to_pmP |BEC tutorial]]''': How intensive is an intensive — in contrast to extensive — quantity?<br> | |||
::::* MitoPedia term — '''[[Intensive quantity]]''' - such as [[force]] and [[pressure]] | |||
|} | |||
---- | |||
2022 Week 43 | |||
*'''Oct-24 Mo''' | |||
:::: '''»[[CRUK Beatson Institute Workshop 2022 Glasgow UK]]«''' Oct 24-25 | |||
---- | |||
*'''Oct-25 Tu'''- Breast Cancer Awareness Month | |||
:{| | |||
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]] | |||
|'''"mtSrc-dependent reduction of mtDNA levels lead to OXPHOS deficiency and a more aggressive phenotype [of breast cancer]. Inhibitors specific for mtSrc could therefore restore mitochondrial activity in TNBC cells, and ultimately stop malignancy"''' <br> | |||
* Djeungoue-Petga MA, Lurette O, Jean S, Hamel-Côté G, Martín-Jiménez R, Bou M, Cannich A, Roy P, Hebert-Chatelain E (2019) Intramitochondrial Src kinase links mitochondrial dysfunctions and aggressiveness of breast cancer cells. [[Djeungoue-Petga 2019 Cell Death Dis|»Bioblast link«]] | |||
:from the O2k-Network »[[CA Moncton Hebert-Chatelain E]]« | |||
|} | |||
---- | |||
*'''Oct-26 We''' | |||
:::: '''»[[13th Targeting Mitochondria Congress 2022 Berlin DE]]«''' Oct 26-28 | |||
---- | |||
*'''Oct-27 Th''' | |||
---- | |||
*'''Oct-28 Fr''' | |||
:{| | |||
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]] | |||
||[[File:Gnaiger 2020 BEC MitoPathways.jpg|left|70px|link=Gnaiger_2020_BEC_MitoPathways|Gnaiger 2020 BEC MitoPathways]] '''[[BEC_tutorial-Living_Communications:_pmF_to_pmP |BEC tutorial]]''': Is the thermodynamics of irreversible processes based on an outdated paradigm?<br> | |||
::::* MitoPedia term — '''[[MitoPedia: Ergodynamics]]''' — '''[[Linear phenomenological laws]]''' | |||
|} | |||
---- | |||
*'''Oct-31 Mo'''- Breast Cancer Awareness Month | |||
:{| | |||
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]] | |||
|'''"Haplogroup D5 [risk factor of breast cancer] exhibited reduced mitochondrial OXPHOS function compared to that of the non-D5 haplogroups […] because of not only lower Complex I activity but also decreased Complex III activity"''' <br> | |||
* Ma L, Fu Q, Xu B, Zhou H, Gao J, Shao X, Xiong J, Gu Q, Wen S, Li F, Shen L, Chen G, Fang H, Lyu J (2017) Breast cancer-associated mitochondrial DNA haplogroup promotes neoplastic growth via ROS-mediated AKT activation. [[Ma 2017 Int J Cancer|»Bioblast link«]] | |||
|} | |||
---- | |||
== Sep 2022 == | |||
*'''Sep- 01 Th''' - Leukemia and Lymphoma Awareness Month | |||
:{| | |||
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]] | |||
|'''Metformin-mediated reduction of mitochondrial activity contributes to decreased cell viability in myeloproliferative neoplasms cells'''<br> | |||
*Machado-Neto JA, Fenerich BA, Scopim-Ribeiro R, Eide CA, Coelho-Silva JL, Dechandt CRP, Fernandes JC, Rodrigues Alves APN, Scheucher PS, Simões BP, Alberici LC, de Figueiredo Pontes LL, Tognon CE, Druker BJ, Rego EM, Traina F (2018) Metformin exerts multitarget antileukemia activity in JAK2V617F-positive myeloproliferative neoplasms. Cell Death Dis 9:311. [[Machado-Neto 2018 Cell Death Dis|»Bioblast link«]] | |||
:from the O2k-Network »[[BR Ribeirao Preto Alberici LC]]« | |||
|} | |||
---- | |||
*'''Sep-02 Fr''' | |||
2022 Week 36 | |||
*'''Sep-05 Mo''' - Prostate Cancer Awareness Month | |||
:{| | |||
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]] | |||
|'''“Mitochondria of the malignant prostate cells have a higher affinity for succinate and this metabolite supports mitochondrial physiology through the induction of expression and activities of mitochondrial complexes”'''<br> | |||
*Bastos Sant'Anna Silva AC, Perez-Valencia JA, Sciacovelli M, Lalou C, Sarlak S, Tronci L, Nikitopoulou E, Meszaros AT, Frezza C, Rossignol R, Gnaiger E, Klocker H (2021) Succinate anaplerosis has an onco-driving potential in prostate cancer cells. Cancers 13:1727.[[Bastos Sant'Anna Silva 2021 Cancers|»Bioblast link«]] | |||
:from the O2k-Network »[[AT Innsbruck Oroboros]]« and »[[FR Bordeaux Rossignol R]]« | |||
|} | |||
---- | |||
*'''Sep-06 Tu''' | |||
:{| | |||
| width="110" align="center" | [[Image:Quality management.png|left|60px|link=http://wiki.oroboros.at/index.php/MitoPedia:_Oroboros_QM |Oroboros quality management]] | |||
|'''How does proficiency testing help achieve quality and reproducibility? '''<br> | |||
Providing a pre-established set of testing criteria improves and standardizes technical performance. <br> | |||
- »'''[[Proficiency test]]'''«<br> | |||
- communicated by »[[Baglivo Eleonora]]« and »[[Tindle-Solomon Lisa]]« | |||
|} | |||
---- | |||
*'''Sep-07 We''' | |||
---- | |||
*'''Sep-08 Th''' | |||
---- | |||
*'''Sep-09 Fr''' | |||
2022 Week 37 | |||
*'''Sep-12 Mo''' | |||
:{| | |||
| width="100" align="center" |[[File:MitoFit Preprints.png|100px|link=https://wiki.oroboros.at/index.php/Torres-Quesada_2022_MitoFit|MitoFit pdf]] | |||
|'''From the [[MitoKIN]] project - preprint to publication:'''<br> | |||
* Torres-Quesada O, Doerrier C, Strich S, Gnaiger E, Stefan E (2022) Physiological cell culture media tune mitochondrial bioenergetics and drug sensitivity in cancer cell models. [[Torres-Quesada 2022 Cancers (Basel)|https://doi.org/10.3390/cancers14163917]] | |||
:from the O2k-Network »[[AT Innsbruck Oroboros]]« | |||
|} | |||
---- | |||
*'''Sep-13 Tu''' | |||
---- | |||
*'''Sep-14 We''' | |||
:{| | |||
| width="100" align="center" |[[File:2022 9 GA.jpg|right|150px|link=https://doi.org/10.26124/bec:2022-0009 |Posch 2022 BEC]] | |||
|'''Bioenerg Commun 2022.9:'''A publication with video presentation from [[Bioblast 2022 |Bioblast 2022: BEC Inaugural Conference]] <br> | |||
*Posch W, Dichtl S, Zaderer V, Lass-Flörl C, Wilflingseder D (2022) How to optimize respiratory models for SARS-CoV-2 research. https://doi.org/10.26124/bec:2022-0009 | |||
|} | |||
---- | |||
*'''Sep-15 Th''' - World Lymphoma Awareness Day | |||
:{| | |||
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]] | |||
|'''OXPHOS as a potential therapeutic target in classical Hodgkin lymphoma'''<br> | |||
*Birkenmeier K, Droese S, Wittig I, Winkelmann R, Käfer V, Doering C, Hartmann S, Wenz T, Reichert AS, Brandt U, Hansmann ML (2016) Hodgkin and Reed-Sternberg cells of classical Hodgkin lymphoma are highly dependent on oxidative phosphorylation. Int J Cancer 138:2231-46. [[Birkenmeier 2016 Int J Cancer|»Bioblast link«]] | |||
:from the O2k-Network »[[DE Frankfurt Droese S]]«, »[[DE Frankfurt Wittig I]]« and »[[NL Nijmegen Brandt U]]« | |||
|} | |||
---- | |||
*'''Sep-16 Fr''' | |||
:::: '''»[[Europhysiology 2022 Copenhagen DK]]«''' Sep 16-18 | |||
2022 Week 38 | |||
*'''Sep-19 Mo''' | |||
:{| | |||
| width="100" align="center" | [[Image:MitoGlobal.jpg|45px|link=https://www.mitoglobal.org/index.php/MitoGlobal_Events|MitoGlobal Events]] | |||
| '''World Mitochondrial Disease Week''' – Sep 18-24<br> | |||
World Mitochondrial Disease Week raises awareness of mitochondrial disease through educational, fundraising and advocacy activities.<br> | |||
See what is happening near you - »https://mitochondrialdiseaseweek.org/events/ | |||
|} | |||
---- | |||
*'''Sep-20 Tu''' | |||
:{| | |||
| width="100" align="center" |[[File:2022.4.jpg|100px|link=https://doi.org/10.26124/bec:2022-0004 |Åsander Frostner 2022 BEC]] | |||
|'''Bioenerg Commun 2022.4: A review on the current landscape of mitochondrial disease drug development'''<br> | |||
*Åsander Frostner E, Simón Serrano S, Chamkha I, Donnelly E, Elmér E, Hansson MJ (2022) Towards a treatment for mitochondrial disease: current compounds in clinical development. https://doi.org/10.26124/bec:2022-0004 | |||
:from the O2k-Network »[[SE Lund Elmer E]]« | |||
|} | |||
---- | |||
*'''Sep-21 We''' | |||
:::: '''»[[The 77th Japanese Society of Physical Fitness and Sports Medicine 2022 Tochigi JP]]«''' Sep 21-23 | |||
:{| | |||
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]] | |||
|''' "By tracing the carbon flow of the nutrients glucose and glutamine in cells derived from patients with different genetically defined causes of primary mitochondrial diseases (PMD), we identified several key metabolic changes supporting the major importance of an NAD<sup>+</sup>/NADH imbalance in PMD." '''<br> | |||
*Adant I, Bird M, Decru B, Windmolders P, Wallays M, de Witte P, Rymen D, Witters P, Vermeersch P, Cassiman D, Ghesquière B (2022) Pyruvate and uridine rescue the metabolic profile of OXPHOS dysfunction. [[Adant 2022 Mol Metab|»Bioblast link«]] | |||
:from the O2k-Network »[[BE Leuven Vermeersch P]]« | |||
|} | |||
---- | |||
*'''Sep-22 Th''' | |||
:::: '''»[[MiPNet27.06 BEC tutorial-Living_Communications pmF |BEC tutorial-Living_Communications ''pmF'']]«''' Prague, Sep 22 | |||
:::: '''»[[EMC2022 Prague CZ]]«''' Sep 22-26 | |||
:{| | |||
| width="100" align="center" | [[File:O2k-brief.png|45px|link=http://wiki.oroboros.at/index.php/O2k-brief|O2k-brief repository]] | |||
|''' A ketogenic diet is a promising approach towards alleviating mitochondrial dysfunction in MELAS disease.''' <br> | |||
* Belal S, Goudenège D, Bocca C, Dumont F, Chao De La Barca JM, Desquiret-Dumas V, Gueguen N, Geffroy G, Benyahia R, Kane S, Khiati S, Bris C, Aranyi T, Stockholm D, Inisan A, Renaud A, Barth M, Simard G, Reynier P, Letournel F, Lenaers G, Bonneau D, Chevrollier A, Procaccio V (2022) Glutamate-induced deregulation of krebs cycle in mitochondrial encephalopathy lactic acidosis syndrome stroke-like episodes (MELAS) syndrome is alleviated by ketone body exposure. [[Belal 2022 Biomedicines|»Bioblast link«]]<br> | |||
:from the O2k-Network »[[FR Angers Gueguen N]]« | |||
|} | |||
---- | ---- | ||
*''' | *'''Sep-23 Fr''' | ||
:{| | :{| | ||
| width="100" align="center" |[[Image: | | width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]] | ||
| - | |'''Investigating the cause of late-onset ''SLC25A26''-related mitochondrial disease'''<br> | ||
* Schober FA, Tang JX, Sergeant K, Moedas MF, Zierz CM, Moore D, Smith C, Lewis D, Guha N, Hopton S, Falkous G, Lam A, Pyle A, Poulton J, Gorman GS, Taylor RW, Freyer C, Wredenberg A (2022) Pathogenic SLC25A26 variants impair SAH transport activity causing mitochondrial disease. [[Schober 2022 Hum Mol Genet|»Bioblast link«]] | |||
:from the O2k-Network »[[BE Leuven Vermeersch P]]« | |||
|} | |} | ||
---- | ---- | ||
*'''Sep-24 Sa''' | |||
---- | |||
*'''Sep-25 Su''' | |||
::::-» '''12:10 (GMT+2): [[Gnaiger Erich|Erich Gnaiger]] presenting at [[EMC2022 Prague CZ]]''' - ''[[Gnaiger 2020 PaduaMuscleDays |Body mass excess, muscle mass, obesity and mitochondrial fitness]]''<br> | |||
---- | |||
2022 Week 39 | |||
*'''Sep-26 Mo''' | |||
:::: '''»[[EMC2022 Prague CZ]]«''' Sep 22-26 | |||
---- | |||
*'''Sep-27 Tu''' | |||
:::: '''»[[EMBO-FEBS Lecture Course 2022 Budva ME]]«''' Sep 27-Oct 1 | |||
---- | |||
*'''Sep-28 We''' | |||
:::: '''»[[BMT 2022 Innsbruck AT]]«''' Sep 28-30 | |||
:{| | :{| | ||
| width="100" align="center" |[[ | | width="100" align="center" |[[File:MitoFit Preprints.png|100px|link=https://wiki.oroboros.at/images/2/23/Fischer_2022_MitoFit_Fe.pdf |MitoFit pdf]] | ||
|''' | |'''“Calcium-induced [mtPTP] is suppressed by exogenous additions of ADP compared to ADP combined with a hexokinase 2-deoxyglucose system of recycling ATP to ADP.”'''<br> | ||
* Bellissimo CA, Sondergaard S, Hughes MC, Ramos SV, Larsen S, Perry CGR (2022) The influence of adenylate cycling on mitochondrial calcium-induced permeability transition pore in permeabilized skeletal muscle fibres. https://doi.org/10.26124/mitofit:2022-0026 | |||
* | :from the O2k-Network »[[CA Toronto Perry CG]]«, »[[DK Copenhagen Larsen S]]« | ||
|} | |} | ||
---- | ---- | ||
*'''Sep-29 Th''' - World Heart Day | |||
:{| | :{| | ||
| width="100" align="center" |[[ | | width="100" align="center" | [[File:O2k-brief.png|45px|link=http://wiki.oroboros.at/index.php/O2k-brief|O2k-brief repository]] | ||
|''' | |''' Respiration compromised in brain and heart tissue homogenate after cardiac arrest and ischemia/reperfusion injury ''' <br> | ||
* Liang L, Zhang G, Cheng C, Li H, Jin T, Su C, Xiao Y, Bradley J, Peberdy MA, Ornato JP, Mangino MJ, Tang W (2021) High-resolution respirometry for evaluation of mitochondrial function on brain and heart homogenates in a rat model of cardiac arrest and cardiopulmonary resuscitation. -[[Liang 2021 Biomed Pharmacother|»Bioblast link«]] | |||
* | : from the O2k-Network »[[US VA Richmond Mangino MJ]]« <br> | ||
|} | |} | ||
---- | ---- | ||
*''' | *'''Sep-30 Fr''' | ||
:::: '''»[[MiPNet27.05_BEC_tutorial-Living_Communications_pmF |BEC tutorial-Living_Communications ''pmF'']]«''' Schröcken, Sep 30 - Oct 2 | |||
:::: Abstract submission deadline for »[[AlgaEurope 2022 Rome IT]]« | |||
:::: Abstract submission deadline for »[[AussieMit 2022 Sydney AU]]« | |||
:::: Abstract submission deadline for »[[CRUK Beatson Institute Workshop 2022 Glasgow UK]]« | |||
---- | |||
== Aug 2022 == | == Aug 2022 == | ||
Line 192: | Line 836: | ||
|} | |} | ||
:::: [[File:EBEClogo2022.jpg|60px|link=https://wiki.oroboros.at/index.php/EBEC2022_Marseille_FR]] <big>'''[[EBEC2022 Aix-en-Provence FR]]'''</big> Aug 20-25 | :::: [[File:EBEClogo2022.jpg|60px|link=https://wiki.oroboros.at/index.php/EBEC2022_Marseille_FR]] <big>'''[[EBEC2022 Aix-en-Provence FR]]'''</big> Aug 20-25 | ||
2022 Week 34 | |||
*'''Aug-22 Mo''' | |||
::: [[File:EBEClogo2022.jpg|60px|link=https://wiki.oroboros.at/index.php/EBEC2022_Marseille_FR]] <big>'''[[EBEC2022 Aix-en-Provence FR]]'''</big> Aug 20-25 | |||
---- | |||
*'''Aug-23 Tu''' | |||
:{| | |||
| width="100" align="center" |[[Image:EBEClogo2022.jpg|70px|left|link=https://wiki.oroboros.at/index.php/EBEC2022_Marseille_FR |EBEC2022]] | |||
| -» '''[[Gnaiger Erich|Erich Gnaiger]] presenting at [[EBEC2022 Aix-en-Provence FR]]''' - [[Went 2021 MitoFit PB|''Oxygen dependence of photosynthesis and light-enhanced dark respiration studied by high-resolution PhotoRespirometry'']]<br> | |||
|} | |||
---- | |||
*'''Aug-24 We''' | |||
:{| | |||
| width="100" align="center" |[[Image:EBEClogo2022.jpg|70px|link=https://wiki.oroboros.at/index.php/EBEC2022_Marseille_FR |EBEC2022]] | |||
|'''A comparison between H<sub>2</sub> and N<sub>2</sub> gases on mitochondrial respiration and H<sub>2</sub>O<sub>2</sub> production''' <br> | |||
-» [[Schmitt Sabine|Sabine Schmitt]] poster presentation at EBEC2022 | |||
* Schmitt S, Gnaiger E (2022) Short-term effect of molecular hydrogen on mitochondrial respiration and hydrogen peroxide production in permeabilized HEK 293T cells. EBEC 2022. [[Schmitt 2022 EBEC|»Bioblast link«]] | |||
|} | |||
---- | |||
*'''Aug-25 Th''' | |||
:{| | |||
| width="100" align="center" |[[Image:EBEClogo2022.jpg|70px|left|link=https://wiki.oroboros.at/index.php/EBEC2022_Marseille_FR |EBEC2022]] | |||
|'''Push and pull effect on the Q-junction''' <br> | |||
-» [[Cardoso Luiza HD|Luiza HD Cardoso]] poster presentation at EBEC2022. | |||
* Cardoso LHD, Donnelly C, Komlodi T, Gnaiger E (2022) Characterizing electron transfer through the mitochondrial Q-junction from fatty acid oxidation and TCA cycle on HEK 293T cells: correlation with respiration. EBEC 2022. [[Cardoso 2022a EBEC|»Bioblast link«]] | |||
|} | |||
---- | |||
*'''Aug-26 Fr''' | |||
2022 Week 35 | |||
*'''Aug-29 Mo''' | |||
:{| | |||
| width="100" align="center" |[[File:NextGenO2k logo.jpg|right|80px|link=https://www.oroboros.at/index.php/product/nextgen-o2k_photobiology/|NextGen-O2k PhotoBiology]] | |||
|'''An article and video about the NextGen-O2k PhotoBiology Module, which was nominated for the Tyrolean Innovation Prize, were recently published (in German).''' <br> | |||
- » [https://www.wko.at/site/tiroler-innovationspreis/oroboros.html Read and watch here] « | |||
|} | |||
---- | |||
*'''Aug-30 Tu''' | |||
:{| | |||
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]] | |||
|'''Keep it running or switch it off – what is best for your O2k?'''<br> | |||
Switching off the O2k after use increases the lifespan of the OroboPOS and saves energy <br> | |||
- »[[MiPNet22.11_O2k-FluoRespirometer_manual]]« and »[[MiPNet19.03_O2k-cleaning_and_ISS]]« <br> | |||
- communicated by »[[Schmitt Sabine]]« and »[[Tindle-Solomon Lisa]]« | |||
|} | |||
---- | |||
*'''Aug-31 We''' | |||
---- | |||
== Jul 2022 == | == Jul 2022 == |
Latest revision as of 15:14, 16 November 2023
Oroboros Ecosystem Agenda 2022 Archive
- Mitochondria and Cell Research - the Oroboros Ecosystem
Dec 2022
2022 Week 49
- Dec- 05 Mo
- Dec- 06 Tu
What is the interaction between acylcarnitines and mitochondrial physiology?
Find out in the review from FAT4BRAIN partners.
- Dambrova M, Cecatto C, Vilskersts R, Liepinsh E (2022) Mitochondrial metabolites acylcarnitines: therapeutic potential and drug targets. Bioenerg Commun 2022.15. https://doi.org/10.26124/bec:2022-0015
- Dec- 07 We
- Dec- 08 Th
Planning to work with the Titration-Injection microPump (TIP2k)?
Prepare your TIP2k for Instrumental O2 background:
- »O2k-Videosupport: Working with the TIP2k (instrumental O2 background)«
- Dec- 09 Fr
2022 Week 50
- Dec- 12 Mo
Bionenerg Commun 2022.17
Alencar et al critically review the main metabolic features of BSF and provide a hypothesis to explain the unusual metabolic network and its biological significance for this parasite form.
- Alencar MB, Ramos EV, Silber AM, Zíková A, Oliveira MF (2022) The extraordinary energy metabolism of the bloodstream Trypanosoma brucei forms: a critical review and hypothesis. Bioenerg Commun 2022.17. https://doi.org/10.26124/bec:2022-0017
- Dec- 13 Tu
- »AlgaEurope 2022 Rome IT« Dec 13-15
- Dec- 14 We
- Dec- 15 Th
- Dec- 16 Fr
2022 Week 51
- Dec- 19 Mo
- Dec- 20 Tu
Cannot open a DatLab file?
Check for special characters in the filename as this can cause problems when opening the file.
- »DatLab error: Could not open file«
- communicated by »Schmitt Sabine« and »Cecatto Cristiane«
- Dec- 21 We
Bionenerg Commun 2022.14
Because the mitochondrial Complex I inhibitor rotenone is widely used to develop experimental models of Parkinson’s disease, Gangly et al examined if rotenone is an inducer of ferroptosis.
- Ganguly U, Bir A, Chakrabarti S (2022) Cytotoxicity of mitochondrial Complex I inhibitor rotenone: a complex interplay of cell death pathways. Bioenerg Commun 2022.14. https://doi.org/10.26124/bec:2022-0014
- Dec- 22 Th
- Dec- 23 Fr
2022 Week 52
- Dec- 26 Mo
- Dec- 27 Tu
Bionenerg Commun 2022.19
Vera-Vives et al describe the setup of a reproducible method for constructing photosynthesis-irradiance curves based on oxygen evolution.
- Vera-Vives AM, Perin G, Morosinotto T (2022) High-resolution photosynthesis-irradiance curves in microalgae. Bioenerg Commun 2022.19. https://doi.org/10.26124/bec:2022-0019
- Dec- 28 We
- Dec- 29 Th
- Dec- 30 Fr
Nov 2022
2022 Week 44
- Nov- 01 Tu
- Nov- 02 We
- Nov- 03 Th
"This tissue [white adipose tissue] shows a persistent mitochondrial dysfunction that compromises tissue metabolic plasticity after obesity"
- Gonzalez-Franquesa A et al (2022) Remission of obesity and insulin resistance is not sufficient to restore mitochondrial homeostasis in visceral adipose tissue. »Bioblast link«
- from the O2k-Network »ES Barcelona Garcia-Roves PM«, »ES Barcelona Claret M« and »DE Cologne Trifunovic A«
- Nov- 04 Fr
- Nov-05 Sa
- Abstract submission open for EUROMIT2023 Bologna IT
2022 Week 45
- Nov- 07 Mo
- Nov- 08 Tu
MCT1 plays a role in diet-induced non-alcoholic fatty liver disease and the associated brain dysfunction.
- Hadjihambi A, Konstantinou C, Klohs J, Monsorno K, Le Guennec A, Donnelly C, Cox J, Kusumbe A, Hosford PS, Soffientini U, Lecca S, Mameli M, Jalan R, Paolicelli RC, Pellerin L (2022) Partial MCT1 invalidation protects against diet-induced non-alcoholic fatty liver disease and the associated brain dysfunction. »Bioblast link«
- from the O2k-Network »CH Lausanne Place N«
- Nov- 09 We
"Monitoring the dissipative component of mitochondrial respiration, efficiency of ATP production, and mitochondrial outer membrane damage during the first 6 h of NMP [normothermic machine perfusion] predicts the clinical outcome of the transplantation."
- Meszaros AT, Hofmann J, Buch ML , Cardini B, Dunzendorfer-Matt T, Nardin F, Blumer MJ, Fodor M, Hermann M, Zelger B, Otarashvili G, Schartner M, Weissenbacher A, Oberhuber R, Resch T, Troppmair J, Öfner D, Zoller H, Tilg H, Gnaiger E, Hautz T, Schneeberger S (2022) Mitochondrial respiration during normothermic liver machine perfusion predicts clinical outcome. »Bioblast link«
- from the O2k-Network »AT Innsbruck Schneeberger S« and »AT Innsbruck Oroboros«
- Nov- 10 Th
"High-altitude of the mountain spa environment improved mitochondrial fitness as could be seen from improved CI-linked OXPHOS and ET capacity of platelet mitochondria of patients with post-COVID-19 syndrome"
- Gvozdjáková A, Sumbalová Z, Kucharská J, Rausová Z, Kovalčíková E, Takácsová T, Navas P, López-Lluch G, Mojto V, Palacka P (2022) Mountain spa rehabilitation improved health of patients with post-COVID-19 syndrome: pilot study. »Bioblast link«
- from the O2k-Network »SK Bratislava Sumbalova Z«
- Nov- 11 Fr
2022 Week 46
- Nov- 14 Mo - World Diabetes Day
Mistimed eating, e.g., during shift-work, disrupts mitochondrial function and could contribute to type-2 diabetes mellitus
- de Goede P, Wüst RCI, Schomakers BV, Denis S, Vaz FM, Pras-Raves ML, van Weeghel M, Yi CX, Kalsbeek A, Houtkooper RH (2022) Time-restricted feeding during the inactive phase abolishes the daily rhythm in mitochondrial respiration in rat skeletal muscle. »Bioblast link«
- from the O2k-Network »NL Amsterdam Wuest RC«
- Nov- 15 Tu
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Again not a Warburg effect - OXPHOS remodeling in high-grade prostate cancer involves mtDNA mutations and increased succinate oxidation Reproducibility is a decisive element in the progress of knowledge. The recent study by Zhang et al (2022) fully confirmed the pattern of OXPHOS remodeling described by Schöpf et al (2020) in prostate cancer.
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- Nov- 16 We
- »AussieMit 2022 Sydney AU« Nov 16-18
- Nov- 17 Th - World Pancreatic Cancer Day
- Nov- 18 Fr
2022 Week 47
- Nov- 21 Mo
"Our results suggest increased proton and electron leak and a decreased ETS capacity in platelets in chronic smoke-exposed animals"
- Białas AJ, Siewiera K, Watała C, Rybicka A, Grobelski B, Kośmider L, Kurek J, Miłkowska-Dymanowska J, Piotrowski WJ, Górski P (2018) Mitochondrial functioning abnormalities observed in blood platelets of chronic smoke-exposed guinea pigs – a pilot study. »Bioblast link«
- from the O2k-Network »PL Lodz Watala C«
- Nov- 22 Tu
Oroboros Instruments supported by WGT-Elektronik wins Cluster Award Life Sciences 2022
- Oxia in the news: Standortagentur Tirol Cluster Awards 2022
- We thank our mechatronics partner WGT Elektronik for a fantastic collaboration!
- Nov- 23 We
Chlorophyll fluorescence: Easy to measure, but not always easy to interpret.
The PAM protocol proposed by Roach (2022) helps deconvolute the various components of non-photochemical quenching in Chlamydomonas reinhardtii.
- Roach T (2022) Chlorophyll fluorescence of Chlamydomonas reinhardtii: insights into the complexities. Bioenerg Commun 2022.10 https://doi.org/10.26124/bec:2022-0010
- Nov- 24 Th
From the Bioblast 2022: BEC Inaugural Conference - a conceptual link to award-winning Oxia:
- Donnelly C, Schmitt S, Cecatto C, Cardoso LHD, Komlódi T, Place N, Kayser B, Gnaiger E (2022) The ABC of hypoxia – what is the norm. Bioenerg Commun 2022.12. https://doi.org/10.26124/bec:2022-0012
- Donnelly C, Schmitt S, Cecatto C, Cardoso LHD, Komlódi T, Place N, Kayser B, Gnaiger E (2022) The ABC of hypoxia – what is the norm. Bioenerg Commun 2022.12. https://doi.org/10.26124/bec:2022-0012
- Nov- 25 Fr
2022 Week 48
- Nov- 28 Mo
- Nov- 29 Tu
"1 mg/L treatment [of microplastics] resulted in a decrease in hepatic mitochondrial respiration and the mitochondrial membrane potential (ΔΨ), both of which were related with suppression of the mitochondrial respiratory chain (CI, CII, CII and CIV)."
- Félix L, Carreira P, Peixoto F (2022) Effects of chronic exposure of naturally weathered microplastics on oxidative stress level, behaviour, and mitochondrial function of adult zebrafish (Danio rerio). »Bioblast link«
- Nov- 30 We
Kinases are central regulators of mitochondria and cancer drugs inhibiting kinases can target mitochondrial functions.
Read how mitochondrial bioenergetics can be used to predict cancer drug off-target effects in the recently published review.
- Torres-Quesada O, Strich S, Stefan E (2022) Kinase perturbations redirect mitochondrial function in cancer. BEC 2022.13. https://doi.org/10.26124/bec:2022-0013
- Dec- 01 Th
- Dec- 02 Fr
Oct 2022
2022 Week 40
- Oct-03 Mo - Breast Cancer Awareness Month
- The Nobel Prize in Physiology or Medicine 2022 was awarded to Svante Pääbo "for his discoveries concerning the genomes of extinct hominins and human evolution" - https://www.nobelprize.org/ - See Neanderthal man.
- Short Oral Presentation submission deadline for »13th Targeting Mitochondria Congress 2022 Berlin DE«
Doxorubicin-transferrin conjugate alters mitochondrial bioenergetics in breast cancer cells
- Wigner P, Zielinski K, Labieniec-Watala M, Marczak A, Szwed M (2021) Doxorubicin-transferrin conjugate alters mitochondrial homeostasis and energy metabolism in human breast cancer cells. »Bioblast link«
- from the O2k-Network »PL Lodz Watala C«
- Oct-04 Tu
“Exposure to fat feeding during pregnancy can provide metabolic advantages in the offspring, which may explain the results of [mice weaned to regular chow] demonstrating improved mitochondrial respiratory function and efficiency in the presence of fatty acid substrates since the heart relies heavily upon efficient fatty acid oxidation to meet its energy demands.”
- Chiñas Merlin A, Gonzalez K, Mockler S, Perez Y, Jia UA, Chicco AJ, Ullevig SL, Chung E (2022) Switching to a standard chow diet at weaning improves the effects of maternal and postnatal high-fat and high-sucrose diet on cardiometabolic health in adult male mouse offspring. »Bioblast link«
- from the O2k-Network »US CO Fort Collins Chicco AJ«
- Oct-05 We
“Mitochondrial Ca2+ handling shapes astrocytic function and is key toward brain homeostasis.”
- Cabral-Costa JV, Kowaltowski AJ (2022) Mitochondrial Ca2+ handling as a cell signaling hub: lessons from astrocyte function. https://doi.org/10.26124/mitofit:2022-0027
- from the O2k-Network »BR Sao Paulo Kowaltowski AJ«
- Oct-06 Th
- Oct-07 Fr
- Poster Presentation submission deadline for »13th Targeting Mitochondria Congress 2022 Berlin DE«
- Oct-08 Sa
- Oct-01 Sa
- Abstract submission deadline for »BPS2023 San Diego US«
2022 Week 41
- Oct-10 Mo - World Mental Health Day
Positive effect of regular physical activity on mitochondrial respiration in burnout syndrome
- Brand S, Ebner K, Mikoteit T, Lejri I, Gerber M, Beck J, Holsboer-Trachsler E, Eckert A (2020) Influence of regular physical activity on mitochondrial activity and symptoms of burnout-an interventional pilot study. J Clin Med 9:E667.»Bioblast link«
- from the O2k-Network »CH Basel Eckert A«
- Oct-11 Tu
- Oct-12 We - Breast Cancer Awareness Month
"NS-linked OXPHOS and ET capacity [were] decreased after prolonged exposure to BAM15."
- Zunica ERM, Axelrod CL, Cho E, Spielmann G, Davuluri G, Alexopoulos SJ, Beretta M, Hoehn KL, Dantas WS, Stadler K, King WT, Pergola K, Irving BA, Langohr IM, Yang S, Hoppel CL, Gilmore LA, Kirwan JP (2021) Breast cancer growth and proliferation is suppressed by the mitochondrial targeted furazano[3,4-b]pyrazine BAM15. »Bioblast link«
- from the O2k-Network »US LA Baton Rouge Noland RC«, »US LA Baton Rouge Irving BA« and »US OH Cleveland Hoppel CL«
- Oct-13 Th
- Oct-14 Fr
- Oct-15 Sa
- Registration open for EUROMIT2023 Bologna IT
2022 Week 42
- Oct-17 Mo
“Chronic nitrate supplementation alone may not be a sufficient stimulus to elicit increases in muscle tissue oxygenation or respiration in [heart failure reduced ejection fraction]”
- Woessner MN, Neil C, Saner NJ, Goodman CA, McIlvenna LC, Ortiz de Zevallos J, Garnham AP, Levinger I, Allen JD (2020) Effect of inorganic nitrate on exercise capacity, mitochondria respiration and vascular function in heart failure reduced ejection fraction. »Bioblast link«
- from the O2k-Network »AU Melbourne Bishop DJ«
- Oct-18 Tu
BEC tutorial: Find out the straight (yet enigmatic) connection between Gibbs energy G [J] and the 'molar Gibbs energy' of a transformation [J·mol-1], which is better called the Gibbs force:
- MitoPedia term — Gibbs energy
- Oct-19 We - Breast Cancer Awareness Month
"Moderate aerobic physical exercise reduces TNBC [Triple-negative breast cancer] tumoral growth with effect on tumor metabolism, characterized by a reduction in mitochondrial respiratory capacity"
- Vulczak A, Souza AO, Ferrari GD, Azzolini AECS, Pereira-da-Silva G, Alberici LC (2020) Moderate exercise modulates tumor metabolism of triple-negative breast cancer. »Bioblast link«
- from the O2k-Network »BR Ribeirao Preto Alberici LC«
- Oct-20 Th
»FAT4BRAIN Symposium Jena DE« Oct 20-21
- Oct-21 Fr
BEC tutorial: How intensive is an intensive — in contrast to extensive — quantity?
- MitoPedia term — Intensive quantity - such as force and pressure
2022 Week 43
- Oct-24 Mo
- »CRUK Beatson Institute Workshop 2022 Glasgow UK« Oct 24-25
- Oct-25 Tu- Breast Cancer Awareness Month
"mtSrc-dependent reduction of mtDNA levels lead to OXPHOS deficiency and a more aggressive phenotype [of breast cancer]. Inhibitors specific for mtSrc could therefore restore mitochondrial activity in TNBC cells, and ultimately stop malignancy"
- Djeungoue-Petga MA, Lurette O, Jean S, Hamel-Côté G, Martín-Jiménez R, Bou M, Cannich A, Roy P, Hebert-Chatelain E (2019) Intramitochondrial Src kinase links mitochondrial dysfunctions and aggressiveness of breast cancer cells. »Bioblast link«
- from the O2k-Network »CA Moncton Hebert-Chatelain E«
- Oct-26 We
- Oct-27 Th
- Oct-28 Fr
BEC tutorial: Is the thermodynamics of irreversible processes based on an outdated paradigm?
- MitoPedia term — MitoPedia: Ergodynamics — Linear phenomenological laws
- Oct-31 Mo- Breast Cancer Awareness Month
"Haplogroup D5 [risk factor of breast cancer] exhibited reduced mitochondrial OXPHOS function compared to that of the non-D5 haplogroups […] because of not only lower Complex I activity but also decreased Complex III activity"
- Ma L, Fu Q, Xu B, Zhou H, Gao J, Shao X, Xiong J, Gu Q, Wen S, Li F, Shen L, Chen G, Fang H, Lyu J (2017) Breast cancer-associated mitochondrial DNA haplogroup promotes neoplastic growth via ROS-mediated AKT activation. »Bioblast link«
Sep 2022
- Sep- 01 Th - Leukemia and Lymphoma Awareness Month
Metformin-mediated reduction of mitochondrial activity contributes to decreased cell viability in myeloproliferative neoplasms cells
- Machado-Neto JA, Fenerich BA, Scopim-Ribeiro R, Eide CA, Coelho-Silva JL, Dechandt CRP, Fernandes JC, Rodrigues Alves APN, Scheucher PS, Simões BP, Alberici LC, de Figueiredo Pontes LL, Tognon CE, Druker BJ, Rego EM, Traina F (2018) Metformin exerts multitarget antileukemia activity in JAK2V617F-positive myeloproliferative neoplasms. Cell Death Dis 9:311. »Bioblast link«
- from the O2k-Network »BR Ribeirao Preto Alberici LC«
- Sep-02 Fr
2022 Week 36
- Sep-05 Mo - Prostate Cancer Awareness Month
“Mitochondria of the malignant prostate cells have a higher affinity for succinate and this metabolite supports mitochondrial physiology through the induction of expression and activities of mitochondrial complexes”
- Bastos Sant'Anna Silva AC, Perez-Valencia JA, Sciacovelli M, Lalou C, Sarlak S, Tronci L, Nikitopoulou E, Meszaros AT, Frezza C, Rossignol R, Gnaiger E, Klocker H (2021) Succinate anaplerosis has an onco-driving potential in prostate cancer cells. Cancers 13:1727.»Bioblast link«
- from the O2k-Network »AT Innsbruck Oroboros« and »FR Bordeaux Rossignol R«
- Sep-06 Tu
How does proficiency testing help achieve quality and reproducibility?
Providing a pre-established set of testing criteria improves and standardizes technical performance.
- »Proficiency test«
- communicated by »Baglivo Eleonora« and »Tindle-Solomon Lisa«
- Sep-07 We
- Sep-08 Th
- Sep-09 Fr
2022 Week 37
- Sep-12 Mo
From the MitoKIN project - preprint to publication:
- Torres-Quesada O, Doerrier C, Strich S, Gnaiger E, Stefan E (2022) Physiological cell culture media tune mitochondrial bioenergetics and drug sensitivity in cancer cell models. https://doi.org/10.3390/cancers14163917
- from the O2k-Network »AT Innsbruck Oroboros«
- Sep-13 Tu
- Sep-14 We
Bioenerg Commun 2022.9:A publication with video presentation from Bioblast 2022: BEC Inaugural Conference
- Posch W, Dichtl S, Zaderer V, Lass-Flörl C, Wilflingseder D (2022) How to optimize respiratory models for SARS-CoV-2 research. https://doi.org/10.26124/bec:2022-0009
- Sep-15 Th - World Lymphoma Awareness Day
OXPHOS as a potential therapeutic target in classical Hodgkin lymphoma
- Birkenmeier K, Droese S, Wittig I, Winkelmann R, Käfer V, Doering C, Hartmann S, Wenz T, Reichert AS, Brandt U, Hansmann ML (2016) Hodgkin and Reed-Sternberg cells of classical Hodgkin lymphoma are highly dependent on oxidative phosphorylation. Int J Cancer 138:2231-46. »Bioblast link«
- from the O2k-Network »DE Frankfurt Droese S«, »DE Frankfurt Wittig I« and »NL Nijmegen Brandt U«
- Sep-16 Fr
- »Europhysiology 2022 Copenhagen DK« Sep 16-18
2022 Week 38
- Sep-19 Mo
World Mitochondrial Disease Week – Sep 18-24
World Mitochondrial Disease Week raises awareness of mitochondrial disease through educational, fundraising and advocacy activities.
See what is happening near you - »https://mitochondrialdiseaseweek.org/events/
- Sep-20 Tu
Bioenerg Commun 2022.4: A review on the current landscape of mitochondrial disease drug development
- Åsander Frostner E, Simón Serrano S, Chamkha I, Donnelly E, Elmér E, Hansson MJ (2022) Towards a treatment for mitochondrial disease: current compounds in clinical development. https://doi.org/10.26124/bec:2022-0004
- from the O2k-Network »SE Lund Elmer E«
- Sep-21 We
"By tracing the carbon flow of the nutrients glucose and glutamine in cells derived from patients with different genetically defined causes of primary mitochondrial diseases (PMD), we identified several key metabolic changes supporting the major importance of an NAD+/NADH imbalance in PMD."
- Adant I, Bird M, Decru B, Windmolders P, Wallays M, de Witte P, Rymen D, Witters P, Vermeersch P, Cassiman D, Ghesquière B (2022) Pyruvate and uridine rescue the metabolic profile of OXPHOS dysfunction. »Bioblast link«
- from the O2k-Network »BE Leuven Vermeersch P«
- Sep-22 Th
- »BEC tutorial-Living_Communications pmF« Prague, Sep 22
- »EMC2022 Prague CZ« Sep 22-26
A ketogenic diet is a promising approach towards alleviating mitochondrial dysfunction in MELAS disease.
- Belal S, Goudenège D, Bocca C, Dumont F, Chao De La Barca JM, Desquiret-Dumas V, Gueguen N, Geffroy G, Benyahia R, Kane S, Khiati S, Bris C, Aranyi T, Stockholm D, Inisan A, Renaud A, Barth M, Simard G, Reynier P, Letournel F, Lenaers G, Bonneau D, Chevrollier A, Procaccio V (2022) Glutamate-induced deregulation of krebs cycle in mitochondrial encephalopathy lactic acidosis syndrome stroke-like episodes (MELAS) syndrome is alleviated by ketone body exposure. »Bioblast link«
- from the O2k-Network »FR Angers Gueguen N«
- Belal S, Goudenège D, Bocca C, Dumont F, Chao De La Barca JM, Desquiret-Dumas V, Gueguen N, Geffroy G, Benyahia R, Kane S, Khiati S, Bris C, Aranyi T, Stockholm D, Inisan A, Renaud A, Barth M, Simard G, Reynier P, Letournel F, Lenaers G, Bonneau D, Chevrollier A, Procaccio V (2022) Glutamate-induced deregulation of krebs cycle in mitochondrial encephalopathy lactic acidosis syndrome stroke-like episodes (MELAS) syndrome is alleviated by ketone body exposure. »Bioblast link«
- Sep-23 Fr
Investigating the cause of late-onset SLC25A26-related mitochondrial disease
- Schober FA, Tang JX, Sergeant K, Moedas MF, Zierz CM, Moore D, Smith C, Lewis D, Guha N, Hopton S, Falkous G, Lam A, Pyle A, Poulton J, Gorman GS, Taylor RW, Freyer C, Wredenberg A (2022) Pathogenic SLC25A26 variants impair SAH transport activity causing mitochondrial disease. »Bioblast link«
- from the O2k-Network »BE Leuven Vermeersch P«
- Sep-24 Sa
- Sep-25 Su
- -» 12:10 (GMT+2): Erich Gnaiger presenting at EMC2022 Prague CZ - Body mass excess, muscle mass, obesity and mitochondrial fitness
- -» 12:10 (GMT+2): Erich Gnaiger presenting at EMC2022 Prague CZ - Body mass excess, muscle mass, obesity and mitochondrial fitness
2022 Week 39
- Sep-26 Mo
- »EMC2022 Prague CZ« Sep 22-26
- Sep-27 Tu
- »EMBO-FEBS Lecture Course 2022 Budva ME« Sep 27-Oct 1
- Sep-28 We
- »BMT 2022 Innsbruck AT« Sep 28-30
“Calcium-induced [mtPTP] is suppressed by exogenous additions of ADP compared to ADP combined with a hexokinase 2-deoxyglucose system of recycling ATP to ADP.”
- Bellissimo CA, Sondergaard S, Hughes MC, Ramos SV, Larsen S, Perry CGR (2022) The influence of adenylate cycling on mitochondrial calcium-induced permeability transition pore in permeabilized skeletal muscle fibres. https://doi.org/10.26124/mitofit:2022-0026
- from the O2k-Network »CA Toronto Perry CG«, »DK Copenhagen Larsen S«
- Sep-29 Th - World Heart Day
Respiration compromised in brain and heart tissue homogenate after cardiac arrest and ischemia/reperfusion injury
- Liang L, Zhang G, Cheng C, Li H, Jin T, Su C, Xiao Y, Bradley J, Peberdy MA, Ornato JP, Mangino MJ, Tang W (2021) High-resolution respirometry for evaluation of mitochondrial function on brain and heart homogenates in a rat model of cardiac arrest and cardiopulmonary resuscitation. -»Bioblast link«
- from the O2k-Network »US VA Richmond Mangino MJ«
- Sep-30 Fr
- »BEC tutorial-Living_Communications pmF« Schröcken, Sep 30 - Oct 2
- Abstract submission deadline for »AlgaEurope 2022 Rome IT«
- Abstract submission deadline for »AussieMit 2022 Sydney AU«
- Abstract submission deadline for »CRUK Beatson Institute Workshop 2022 Glasgow UK«
Aug 2022
2022 Week 31
- Aug-01 Mo
154th Oroboros O2k-Coaching Days - Advanced and NextGen-O2k Aug 1-5
O2k-checklist: Get started with an O2k-experiment
The O2k-checklist provides an overview of all essential steps for starting an O2k-experiment.
- » MiPNet20.04_O2k-checklist«
- » communicated by »Cecatto Cristiane« and »Schmitt Sabine«
- Aug-02 Tu
154th Oroboros O2k-Coaching Days - Advanced and NextGen-O2k Aug 1-5
What are the substrate-uncoupler-inhibitor titration reference protocols?
These protocols provide a common baseline for comparison of mitochondrial respiratory control in a large variety of species, tissues and cell types, mt-preparations and laboratories.
- » SUIT reference protocol«- communicated by »Cardoso Luiza HD« and »Tindle-Solomon Lisa«
- Aug-03 We
154th Oroboros O2k-Coaching Days - Advanced and NextGen-O2k Aug 1-5
O2 flux analysis with DatLab 7.4
Use the O2 analysis template:
- Aug-04 Th
154th Oroboros O2k-Coaching Days - Advanced and NextGen-O2k Aug 1-5
Why do we perform multiple H2O2 calibrations in the Amplex® UltraRed assay?
The sensitivity to H2O2 of the fluorometric signal changes during the experiment as a function of: (1) experimental time and accumulating UltroxRed (similar to resorufin), (2) changes of the optical properties due to titrations, and (3) the radical scavenging capacity of the sample. Therefore, H2O2 calibrations are performed before and after sample addition, and after selected titration steps.
- »Amplex UltraRed« and »Komlodi et al BEC 2021.4«
- Aug-05 Fr
154th Oroboros O2k-Coaching Days - Advanced and NextGen-O2k Aug 1-5
Watch these videos to get started with the Q-Module
2022 Week 32
- Aug-08 Mo
- DatLab 7.4 is available to download free of charge for all customers.
- Please note support for earlier versions will no longer be possible.
- -»Download here«
- DatLab 7.4 is available to download free of charge for all customers.
- Aug-09 Tu
Bioenerg Commun 2022.8: Quality Control
- Baglivo E, Cardoso LHD, Cecatto C, Gnaiger E (2022) Statistical analysis of instrumental reproducibility as internal quality control in high-resolution respirometry. https://doi.org/10.26124/bec:2022-0008
- from the O2k-Network »AT Innsbruck Oroboros«
- Aug-10 We
- Aug-11 Th
- Oroboros innovation: the Sample Holder protecting susceptible samples from damage by stirring in the O2k-chamber.
- Oroboros innovation: the Sample Holder protecting susceptible samples from damage by stirring in the O2k-chamber.
- Aug-12 Fr
2022 Week 33
- Aug-15 Mo
BEC tutorial: Did you know that a cell respiring O2 at 100 amol·s-1·x-1 consumes 60 million O2 molecules per second per cell?
- Apply the Avogadro constant NA and SI prefixes; check Formats: INO2 = InO2 · NA
- Apply the Avogadro constant NA and SI prefixes; check Formats: INO2 = InO2 · NA
InO2 = 100 (amol O2)·s-1·(x cell)-1
INO2 = 60.2·106 (x O2)·s-1·(x cell)-1
- Aug-16 Tu
Exploring photosynthesis and dark respiration in the microalgae Chlamydomonas reinhardtii
- Went N, Di Marcello M, Gnaiger E (2021) Oxygen dependence of photosynthesis and light-enhanced dark respiration studied by High-Resolution PhotoRespirometry. MitoFit Prep 2021.5. doi:10.26124/mitofit:2021-0005
- Aug-17 We
- Aug-18 Th
- Aug-19 Fr
- Aug-20 Sa
Oroboros Instruments has been selected as a Euregio Innovation Prize 2022 finalist for the PB-Module of the NextGen-O2k.
The regions of Tyrol – South Tyrol – Trentino will award the prize to innovations in the health and life sciences.
We are looking forward to presenting our innovation in front of the jury on August 20 at 14:00 in Alpbach, AT.
- » Euregio-Innovationspreis«
EBEC2022 Aix-en-Provence FR Aug 20-25
2022 Week 34
- Aug-22 Mo
EBEC2022 Aix-en-Provence FR Aug 20-25
- Aug-23 Tu
-» Erich Gnaiger presenting at EBEC2022 Aix-en-Provence FR - Oxygen dependence of photosynthesis and light-enhanced dark respiration studied by high-resolution PhotoRespirometry
- Aug-24 We
A comparison between H2 and N2 gases on mitochondrial respiration and H2O2 production
-» Sabine Schmitt poster presentation at EBEC2022
- Schmitt S, Gnaiger E (2022) Short-term effect of molecular hydrogen on mitochondrial respiration and hydrogen peroxide production in permeabilized HEK 293T cells. EBEC 2022. »Bioblast link«
- Aug-25 Th
Push and pull effect on the Q-junction
-» Luiza HD Cardoso poster presentation at EBEC2022.
- Cardoso LHD, Donnelly C, Komlodi T, Gnaiger E (2022) Characterizing electron transfer through the mitochondrial Q-junction from fatty acid oxidation and TCA cycle on HEK 293T cells: correlation with respiration. EBEC 2022. »Bioblast link«
- Aug-26 Fr
2022 Week 35
- Aug-29 Mo
An article and video about the NextGen-O2k PhotoBiology Module, which was nominated for the Tyrolean Innovation Prize, were recently published (in German).
- » Read and watch here «
- Aug-30 Tu
Keep it running or switch it off – what is best for your O2k?
Switching off the O2k after use increases the lifespan of the OroboPOS and saves energy
- »MiPNet22.11_O2k-FluoRespirometer_manual« and »MiPNet19.03_O2k-cleaning_and_ISS«
- communicated by »Schmitt Sabine« and »Tindle-Solomon Lisa«
- Aug-31 We
Jul 2022
2022 Week 27
- Jul- 04 Mo
A publication from Bioblast 2022: BEC Inaugural Conference
- Heimler SR, Phang HJ, Bergstrom J, Mahapatra G, Dozier S, Gnaiger E, Molina AJA (2021) Platelet bioenergetics are associated with resting metabolic rate and exercise capacity in older adult women. https://doi.org/10.26124/bec:2022-0002
- Jul- 05 Tu
A publication from Bioblast 2022: BEC Inaugural Conference
- Abed Rabbo M, Stiban J (2022) NUBPL: a mitochondrial Complex I deficiency disorder. https://doi.org/10.26124/bec:2022-0003
- Jul- 06 We
A publication from Bioblast 2022: BEC Inaugural Conference
- Åsander Frostner E, Simón Serrano S, Chamkha I, Donnelly E, Elmér E, Hansson MJ (2022) Towards a treatment for mitochondrial disease: current compounds in clinical development. https://doi.org/10.26124/bec:2022-0004
- Jul- 07 Th
Take some time for history - it adds to your stories:
- Jul- 08 Fr
2022 Week 28
- Jul- 11 Mo
A publication from Bioblast 2022: BEC Inaugural Conference
- Heichler C, Nagy M, Wolf P (2022) Evaluation of hepatotoxic effects of acetaminophen on HepG2 cells by parallel real-time monitoring in a multi-sensor analysis platform for automated cell-based assays. https://doi.org/10.26124/bec:2022-0006
- Jul- 12 Tu
BEC tutorial: Mitochondrial membrane potential and Peter Mitchell’s protonmotive force: elements of the science of bioenergetics.
» BEC tutorial-Living Communications pmF, Schroecken, Austria; 2022 - Sep 30 to Oct 2 - preceding the Oroboros O2k-Workshop on high-resolution respirometry.
- Gnaiger E (2020) Mitochondrial pathways and respiratory control. An introduction to OXPHOS analysis. 5th ed. https://doi.org/10.26124/bec:2020-0002
- Jul- 13 We
- "Assuming a publication charge of € 1200 per article, scientists mentioning mitochondria or photosynthesis pay € 100 000 every day in 2021 for ‘selling’ their output to publishers ― over € 36 Mill per year."
- - Gnaiger E (2021) Beyond counting papers – a mission and vision for scientific publication. https://doi.org/10.26124/bec:2021-0005
- Jul- 14 Th
- Jul- 15 Fr
New version 2 of a preprint from Bioblast 2022: BEC Inaugural Conference
- Donnelly C, Schmitt S, Cecatto C, Cardoso LHD, Komlodi T, Place N, Kayser B, Gnaiger E (2022) The ABC of hypoxia – what is the norm. https://doi.org/10.26124/mitofit:2022-0025.v2
2022 Week 29
- Jul- 18 Mo
What is research?
- »Research«
- Jul- 19 Tu
Do you want to find the best SUIT protocol for your research questions?
- Use the SUITbrowser: »SUITbrowser«
- Jul- 20 We
- Jul- 21 Th
Planning to measure proton flux or mitochondrial membrane potential with ion-selective electrodes in the O2k?
Learn how to assemble the reference electrodes:
- »O2k-Videosupport: Assembly of the reference electrode«
- communicated by »Cardoso Luiza« and »Schmitt Sabine«
- Jul- 22 Fr
2022 Week 30
- Jul-25 Mo
Do scientists take responsibility for energy saving? - Or does biomedical research merely find excuses?
- »Energy saving in research« — more details: MitoPedia: Oroboros QM
- Jul-26 Tu
- Jul-27 We
Body mass M and mass m - what is the difference? Consult MitoPedia for a comment on body mass versus body weight.
- »Body mass with a link to mitObesity«
- Jul-28 Th - World Hepatitis Day
Cells expressing hepatitis B protein X showed increased ROUTINE, LEAK and ET capacity compared to control cells.
- Wang B, Li W, Fang H, Zhou H (2018) Hepatitis B virus infection is not associated with fatty liver disease: Evidence from a cohort study and functional analysis. Mol Med Rep 19:320-26. »Bioblast link«
- Jul-29 Fr
Jun 2022
2022 Week 23
- Jun- 06 Mo
Scientific journals apply yesterday's concepts in the various formats of references with bewildering abbreviations of journals, volumes, issues, page numbers. We can do today's job much better using the BEC https-format — in line with DORA.
- Jun- 07 Tu
- Jun- 08 We - World Brain Tumor Day 2021
- »ESCI 2022 Bari IT« Jun 8-10
- Erich Gnaiger presenting at ESCI 2022 Bari IT - Bioenergetic cluster analysis – diagnostic evaluation of mitochondrial respiratory control in human fibroblasts
- Jun- 09 Th
Are you a beginner or need a refresher on using SUIT protocols with DatLab7.4?
- »O2k-Videosupport: How to perform an experiment with a SUIT DL-Protocol« and »Run DL-Protocol/Set O2 limit in DatLab«
- communicated by »Schmitt Sabine«
- Jun- 10 Fr
- »ESCI 2022 Bari IT«
- Eleonora Baglivo presenting at ESCI 2022 Bari IT - Quality control of mitochondrial respiration medium in high-resolution respirometry with living and permeabilized cells - poster selected for oral presentation
2022 Week 24
- Jun- 13 Mo
- Jun- 14 Tu - World Blood Donor Day
- Jun- 15 We
The central role of the Q-junction in mitochondria
The Q-junction is a point of convergence in the electron transfer system. Electrons flow from different dehydrogenases and respiratory Complexes into the Q-junction and then downstream to Complex III.
- »Q-junction«
- communicated by »Schmitt Sabine«
- Jun- 16 Th
- Jun- 17 Fr
The final program of Bioblast 2022 at a glance
2022, Jun 29 - 30 *** 8 sessions *** Poster session *** Exhibition *** MiPArt *** Social activities
- »Bioblast_2022 Program overview«
- Jun- 18 Sa
BEC 2022.1. - The book of abstracts is online
Gnaiger E, Cardoso LHD, Tindle-Solomon L, Cocco P, eds (2022) Bioblast 2022: BEC inaugural conference. https://doi.org/10.26124/bec:2022-0001
- »Bioenerg Commun 2022.1.«
2022 Week 25
- Jun- 20 Mo
BEC 2022.1. - The book of abstracts is online (2022-06-18)
Gnaiger E, Cardoso LHD, Tindle-Solomon L, Cocco P, eds (2022) Bioblast 2022: BEC inaugural conference. https://doi.org/10.26124/bec:2022-0001
- »Bioenerg Commun 2022.1.«
- Jun- 21 Tu
The final program of Bioblast 2022 at a glance
2022, Jun 29 - 30 *** 8 sessions *** Poster session *** Exhibition *** MiPArt *** Social activities
- »Bioblast_2022 Program overview«
- Jun- 22 We
Co-write a BEC editorial
Join the discussion on Jun 30
- » BEC is the future«
- Jun- 23 Th
10+5 min = 600+300 s or 5 min = 300 s
A maximum of 12 or 5 slides - look at abstracts to come prepared
- »Bioblast_2022 Abstracts of oral presentations«
- Jun- 24 Fr
Posters and exhibition
Speakers: stick to the timeline and join the poster sessions and visit the exhibition
- »Bioblast_2022 Abstracts of poster presentations«
2022 Week 26
- Jun- 27 Mo
Posters and exhibition
Speakers: stick to the timeline and join the poster sessions and visit the exhibition
- »Bioblast_2022 Abstracts of poster presentations«
- Jun- 28 Tu
10+5 min = 600+300 s or 5 min = 300 s
A maximum of 12 or 5 slides - look at abstracts to come prepared
- »Bioblast_2022 Abstracts of oral presentations«
- Jun- 29 We
Bioblast 2022 Jun 29-30
- Jun- 30 Th
Bioblast 2022 Jun 29-30
- Jul- 01 Fr
- Jul- 02 Sa
May 2022
2022 Week 18
- May- 02 Mo - Lyme Disease Awareness Month
»FAT4BRAIN Workshop IOC151 Innsbruck AT« May 2-3
- May- 03 Tu
- May- 04 We
"More systematic profiling of mitochondrial bioenergetic states in the presence and absence of lead molecules or kinase drugs could become an asset for anticipating non-desired off-target drug features."
Torres-Quesada Omar, Strich Sophie, Stefan Eduard (2022) Kinase perturbations redirect mitochondrial function. MitoFit Prep 2022.11. https://doi.org/10.26124/mitofit:2022-0011
- from the O2k-Network »AT Innsbruck Oroboros«
- May- 05 Th
- May- 06 Fr
2022 Week 19
- May- 09 Mo
- May- 10 Tu
- May- 11 We
- May- 12 Th - International Awareness Day for Chronic Immunological and Neurological Diseases
- May- 13 Fr
- May- 14 Sa
- 13:15-14:15 (GMT+2): 152nd Oroboros O2k-Workshop: Continuous monitoring of mitochondrial Coenzyme Q redox state integrated in high-resolution respirometry at 10th Conference of the International Coenzyme Q10 Association 2022 Hamburg DE
- 16:30 (GMT+2): Gnaiger Erich presenting at 10th Conference of the International Coenzyme Q10 Association 2022 Hamburg DE - The mitochondrial Q-junction and coenzyme Q pools: Continuous monitoring of pull and push control of respiration and redox state of the Q-mimetic CoQ2
2022 Week 20
- May- 16 Mo
- May- 17 Tu
How do you know which digitonin concentration to use for permeabilization of the cell plasma membrane when performing experiments with the O2k?
SUIT-010 was designed to determine the optimum digitonin concentration for permeabilization of the cell plasma membrane without damaging the mitochondrial outer membrane.
- »Optimum Digitonin concentration and SUIT-010«
- communicated by »Schmitt Sabine« and »Cecatto Cristiane«
- May- 18 We
- May- 19 Th
"Instrumental QC is a cornerstone for experimental reproducibility."
- Baglivo E, Cardoso LHD, Cecatto C, Gnaiger E (2022) Statistical analysis of instrumental reproducibility as internal quality control in high-resolution respirometry. MitoFit Preprints 2022.18. https://doi.org/10.26124/mitofit:2022-0018.v2
- from the O2k-Network »AT Innsbruck Oroboros«
- May- 20 Fr
2022 Week 21
- May- 23 Mo
- May- 24 Tu
Do you know the different ways to adjust oxygen concentration in the Oroboros O2k?
- May- 25 We
Do you load the correct instrumental background correction according to the actual range of experimental O2 concentrations?
Perform and apply the instrumental background test:
- »O2 background correction in DatLab« and »Instrumental oxygen background«
- May- 26 Th
- May- 27 Fr
Apr 2022
2022 Week 14
- Apr- 04 Mo - April is Parkinson's Awareness Month
"Early stage α-synuclein pathology does not influence mitochondrial respiration in the striatum and amygdala [of mice]"
- Burtscher J, Copin JC, Sandi C, Lashuel HA (2020) Pronounced α-synuclein pathology in a seeding-based mouse model is not sufficient to induce mitochondrial respiration deficits in the striatum and amygdala. eNeuro 7:ENEURO.0110-20.2020. »Bioblast link«
- from the O2k-Network »CH Lausanne Place N« and »CH Lausanne Sandi C«
- Apr- 05 Tu
- Apr- 06 We
- Apr- 07 Th - World Health Day
- Apr- 08 Fr
2022 Week 15
- Apr- 11 Mo - World Parkinson´s Disease Day
Reviewing cellular models to decipher the mechanisms of mitochondrial dysfunction in Parkinson's disease
- Krako Jakovljevic N, Ebanks B, Katyal G, Chakrabarti L, Markovic I, Moisoi N (2021) Mitochondrial homeostasis in cellular models of Parkinson’s disease. Bioenerg Commun 2021.2. https://doi.org/10.26124/bec:2021-0002
- from the O2k-Networks »RS Belgrade Lalic NM«, »UK Nottingham Chakrabarti L« and »UK Leicester Moisoi N«
- Apr- 12 Tu
- Apr- 13 We
- Apr- 14 Th
Did you know that you can apply instrumental O2 background test parameters (i.e., intercept and slope) from an existing file in DatLab?
In the DatLab file, you can copy the Instrumental O2 background test parameters directly via the ‘Copy from file’ option in the ‘Slope configuration’ window. For more information, see: - »Copy from file«
- communicated by »Cecatto Cristiane«
- Apr- 15 Fr
2022 Week 16
- Apr- 18 Mo
- Apr- 19 Tu
"The physiological Human Plasma-Like Media alters proliferative behavior, mitochondrial bioenergetic states and kinase drug sensitivity of cancer cells when compared to classic cell culture media."
- Torres-Quesada O, Doerrier C, Strich S, Gnaiger E, Stefan E (2022) Human Plasma-Like Media fine-tune mitochondrial function and alter drug sensitivity in cancer cell lines. MitoFit Preprints 2022.8. https://doi.org/10.26124/mitofit:2022-0008
- from the O2k-Network »AT Innsbruck Oroboros«
- Apr- 20 We
- Apr- 21 Th
- Apr- 22 Fr - Earth Day 2022
2022 Week 17
- Apr- 25 Mo
"Proline catabolism through ProDH generates sufficient CIII and CIV proton pumping, supporting ATP production by F1FO-ATPase even when CI is inhibited"
Pallag G, Nazarian S, Ravasz D, Bui D, Komlódi T, Doerrier C, Gnaiger E, Seyfried TN, Chinopoulos C (2022) Proline oxidation leading to high electron flow through reduction of ubiquinone supports ATP production by F1FO-ATPase in mitochondria with inhibited Complex I. MitoFit Preprints 2022.1.v3. https://doi.org/10.26124/mitofit:2022-0001.v3
- from the O2k-Network »AT Innsbruck Oroboros« and »HU Budapest Chinopoulos C«
- Apr- 26 Tu
- Apr- 27 We
- Apr- 28 Th
- Apr- 29 Fr
Mar 2022
2022 Week 9
- Feb- 28 Mo - Rare disease day
Oroboros Instruments is pleased to collaborate in the CureMILS project
Led by O2k-Network member, Alessandro Prigione, the project aims to employ a novel approach to enable drug discovery for treatment of Mitochondrial DNA (mtDNA)-associated Leigh syndrome (MILS).
- - »CureMILS«
- Mar- 01 Tu - Multiple Sclerosis Awareness Month
- Presenting data from a pilot study on mitochondria bioenergetics and PTSD, Alexander Karabatsiakis will join us at Bioblast 2022.
- -»Bioblast 2022« , »Karabatsiakis Alexander«
- Presenting data from a pilot study on mitochondria bioenergetics and PTSD, Alexander Karabatsiakis will join us at Bioblast 2022.
- Mar- 02 We
- NextGen-O2k key opinion leader Tomas Morosinotto has confirmed his talk on Photosynthetic capacity under oscillating light regimes at Bioblast 2022.
- -»Bioblast 2022« , »Morosinotto Tomas«
- NextGen-O2k key opinion leader Tomas Morosinotto has confirmed his talk on Photosynthetic capacity under oscillating light regimes at Bioblast 2022.
- Mar- 03 Th - World Wildlife Day
- Mar- 04 Fr
- Luboš Sobotka from Charles University, CZ will present The Crabtree effect and clinical nutrition at Bioblast 2022.
- -»Bioblast 2022« , »Sobotka Lubos«
- Luboš Sobotka from Charles University, CZ will present The Crabtree effect and clinical nutrition at Bioblast 2022.
2022 Week 10
- Mar- 07 Mo
- Johnny Stiban from Birzeit University, PS will be presenting Barth Syndrome: A Genetic Ailment with a Lipid Component and Bioenergetic Ramifications at Bioblast 2022.
- -»Bioblast 2022« , »Stiban Johnny«
- Johnny Stiban from Birzeit University, PS will be presenting Barth Syndrome: A Genetic Ailment with a Lipid Component and Bioenergetic Ramifications at Bioblast 2022.
- Mar- 08 Tu - International Women´s Day
- Mar- 09 We
- From the Medical University Innsbruck, AT we will have Günter Weiss presenting on the linkage of iron availability to mitochondrial function.
- -»Bioblast 2022« , »Weiss Guenter«
- From the Medical University Innsbruck, AT we will have Günter Weiss presenting on the linkage of iron availability to mitochondrial function.
- Mar- 10 Th - World Kidney Day
"AT1 receptors and AT2 receptors are expressed in kidney mitochondria and can directly regulate mitochondrial respiration."
- Friederich-Persson M, Persson P (2020) Mitochondrial angiotensin II receptors regulate oxygen consumption in kidney mitochondria from healthy and type 1 diabetic rats. Am J Physiol Renal Physiol 318:F683-88. »Bioblast link«
- from the O2k-Network »SE Uppsala Liss P«
- Sasanka Chakrabarti has confirmed his Bioblast 2022 presentation on rotenone cytotoxicity on SH-SY5Y cells.
- -»Bioblast 2022« , »Chakrabarti Sasanka«
- Sasanka Chakrabarti has confirmed his Bioblast 2022 presentation on rotenone cytotoxicity on SH-SY5Y cells.
- Mar- 11 Fr
- The O2k-Network lab of Stefan Schneeberger at the Medical University Innsbruck, AT will be presenting Pre-transplant mitochondrial respiration as a clinical prognostic marker in liver machine perfusion at Bioblast 2022.
- -»Bioblast 2022« , »AT Innsbruck Schneeberger S«
- The O2k-Network lab of Stefan Schneeberger at the Medical University Innsbruck, AT will be presenting Pre-transplant mitochondrial respiration as a clinical prognostic marker in liver machine perfusion at Bioblast 2022.
2022 Week 11
- Mar- 14 Mo
- TissueModels project partner Markus Keller will present Lipidomics of mitochondrial membranes - methods first at Bioblast 2022.
- -»Bioblast 2022« , »TissueModels«
- TissueModels project partner Markus Keller will present Lipidomics of mitochondrial membranes - methods first at Bioblast 2022.
- Mar- 15 Tu
"MDH2 is a metabolic switch rewiring [electron transfer system] and TCA fuelling"
- Molinié T, Cougouilles E, David C, Cahoreau E, Portais JC, Mourier A (2022) MDH2 produced OAA is a metabolic switch rewiring the fuelling of respiratory chain and TCA cycle. Biochim Biophys Acta Bioenerg 1863:148532. »Bioblast link«
- from the O2k-Network »FR Bordeaux Mourier A«
- Mar- 16 We
Bioenergetics Communications has signed the Declaration on Research Assessment DORA. «
- Mar- 17 Th
- NextGen-O2k key opinion leader Anthony Moore will give a talk on the bioenergetics of alternative oxidases at Bioblast 2022.
- -»Bioblast 2022« , »Moore Anthony L«
- NextGen-O2k key opinion leader Anthony Moore will give a talk on the bioenergetics of alternative oxidases at Bioblast 2022.
- Mar- 18 Fr
Paywall journalism is the opposite of Open Access.
Though often defined from the individual reader's perspective, a paywall can also apply to an institution (such as a library) or the author.
- »Paywall journalism« , »Gnaiger (2021) Editorial Bioenerg Commun«
2022 Week 12
- Mar- 21 Mo - World Down Syndrome Day
"A correlation between the reduced respiratory activity and the morphological alterations in DS-HFF [Down Syndrome human primary lines of foetal fibroblasts] mitochondria indicates that the occurrence of de-structured cristae might partly account for the dysfunctioning oxidative phosphorylation in trisomic samples"
- Piccoli C, Izzo A, Scrima R, Bonfiglio F, Manco R, Negri R, Quarato G, Cela O, Ripoli M, Prisco M, Gentile F, Calì G, Pinton P, Conti A, Nitsch L, Capitanio N (2013) Chronic pro-oxidative state and mitochondrial dysfunctions are more pronounced in fibroblasts from Down syndrome foeti with congenital heart defects. Hum Mol Genet 22:1218-32. »Bioblast link«
- from the O2k-Network »IT Foggia Capitanio N«
- Mar- 22 Tu
- At Bioblast 2022 Leonid A Sazanov will present Why Complex I - Complex II is complex too.
- -»Bioblast 2022« , »Sazanov Leonid A«
- At Bioblast 2022 Leonid A Sazanov will present Why Complex I - Complex II is complex too.
- Mar- 23 We
- Charles Hoppel will contribute to Bioblast 2022 with his talk on diagnostic monitoring of skeletal mitochondrial metabolism.
- -»Bioblast 2022« , »Hoppel Charles L«
- Charles Hoppel will contribute to Bioblast 2022 with his talk on diagnostic monitoring of skeletal mitochondrial metabolism.
- Mar- 24 Th - World Tuberculosis Day
- Mar- 25 Fr
An article about the NextGen-O2k was recently published in six languages on the CORDIS EU website.
- » Read here «
2022 Week 13
- Mar- 28 Mo
- Mar- 29 Tu
- Mar- 30 We
- »Mitochondrial Communications Serial Webinar 4 2022 Virtual« 20:00-21:30 (GMT+8)
- Mar- 31 Th
- Shilpa Iyer has confirmed her contribution Understanding Bioenergetics health index and disease severity in mitochondrial disease fibroblasts to Bioblast 2022.
- -»Bioblast 2022« , »Iyer Shilpa«
- Shilpa Iyer has confirmed her contribution Understanding Bioenergetics health index and disease severity in mitochondrial disease fibroblasts to Bioblast 2022.
- Apr- 01 Fr - Parkinson´s Awareness Month
Feb 2022
2022 Week 5
- Jan- 31 Mo
- Feb- 01 Tu
From preprint to journal publication:
- Vernerova A, Garcia-Souza LF, Soucek O, Kostal M, Rehacek V, Krcmova LK, Gnaiger E, Sobotka O (2021) Mitochondrial respiration of platelets: comparison of isolation methods. Biomedicines 9:1859. doi.org/10.3390/biomedicines9121859
- from the O2k-Network »CZ Hradec Kralove Cervinkova Z« and »AT Innsbruck Oroboros«
- Feb- 02 We
- Feb- 03 Th
- Feb- 04 Fr
Acute sarcoplasmic reticulum calcium leak increases mitochondrial respiration after simulated sprint interval training
- Zanou N, Dridi H, Reiken S, Imamura de Lima T, Donnelly C, De Marchi U, Ferrini M, Vidal J, Sittenfeld L, Feige JN, Garcia-Roves PM, Lopez-Mejia IC, Marks AR, Auwerx J, Kayser B, Place N (2021) Acute RyR1 Ca2+ leak enhances NADH-linked mitochondrial respiratory capacity. Nat Commun 12:7219. »Bioblast link«
- from the O2k-Network »CH Lausanne Place N« and »ES Barcelona Garcia-Roves PM«
- Zanou N, Dridi H, Reiken S, Imamura de Lima T, Donnelly C, De Marchi U, Ferrini M, Vidal J, Sittenfeld L, Feige JN, Garcia-Roves PM, Lopez-Mejia IC, Marks AR, Auwerx J, Kayser B, Place N (2021) Acute RyR1 Ca2+ leak enhances NADH-linked mitochondrial respiratory capacity. Nat Commun 12:7219. »Bioblast link«
2022 Week 6
- Feb- 07 Mo
- Save-the-date: Bioblast 2022: BEC Inaugural Conference - Jun 28 - Jul 1
- -»Bioblast 2022: Announcements«
- Save-the-date: Bioblast 2022: BEC Inaugural Conference - Jun 28 - Jul 1
- Feb- 08 Tu
Now accepting living communications for Bioblast 2022 - BEC Inaugural Issue
-»More details«
- Feb- 09 We
'The scientific literature is exploding in quantity even as it stands still in literary quality.' - Wells WA (2004) Me write pretty one day: how to write a good scientific paper. J Cell Biol 165:757-8. »Bioblast link« Sequential editions provide an opportunity to improve quality while preventing explosions on quantity. - Gnaiger (2021) Editorial Bioenerg Commun
- Feb- 10 Th
Alterations in molecular and cellular pathways contribute to skeletal muscle-related symptoms in Covid-19 - Soares MN, Eggelbusch M, Naddaf E, Gerrits KHL, van der Schaaf M, van den Borst B, Wiersinga WJ, van Vugt M, Weijs PJM, Murray AJ, Wüst RCI (2022) Skeletal muscle alterations in patients with acute Covid-19 and post-acute sequelae of Covid-19. J Cachexia Sarcopenia Muscle. »Bioblast link«
- from the O2k-Network »NL Amsterdam Wuest RC« and »UK Cambridge Murray AJ«
- Feb- 11 Fr - International Day of Women and Girls in Science
© WK Tirol/ Die Fotografen Oroboros is proud to be one of the top 3 nominees for the Tyrolean Innovation Award for the PhotoBiology-Module.
Following the award ceremony organized by the Tyrolean Chamber of Commerce, state council member Anton Mattle, responsible for economy and industry in Tyrol, accepted our invitation to the opening ceremony of Bioblast 2022.
- -»PB-Module« , »Bioblast 2022«
2022 Week 7
- Feb- 14 Mo - Donor Day
- MitoKIN project partners Eduard Stefan and Omar Torres-Quesada will present Profiling of allosteric kinase inhibitors: a new way to unveil metabolic changes by boosting or preventing mitochondrial function at Bioblast 2022.
- -»Bioblast 2022« , »MitoKIN«
- MitoKIN project partners Eduard Stefan and Omar Torres-Quesada will present Profiling of allosteric kinase inhibitors: a new way to unveil metabolic changes by boosting or preventing mitochondrial function at Bioblast 2022.
- Feb- 15 Tu - International Childhood Cancer Day
- Feb- 16 We
- Werner Koopman has confirmed his presentation at Bioblast 2022 on mitochondrial targeting using the TPP moiety.
- -»Bioblast 2022« , »Koopman Werner JH«
- Werner Koopman has confirmed his presentation at Bioblast 2022 on mitochondrial targeting using the TPP moiety.
- Feb- 17 Th
Read more about the Tyrolean Innovation Award for which we were a top nominee.
- -»Tiroler Wirtshaft article (German)«
- Feb- 18 Fr
2022 Week 8
- Feb- 21 Mo
- The O2k-Network lab of Laszlo Tretter at Semmelweis University in Budapest, HU will be presenting The protonmotive force - not merely membrane potential at Bioblast 2022.
- -»Bioblast 2022« , »HU Budapest Tretter L«
- The O2k-Network lab of Laszlo Tretter at Semmelweis University in Budapest, HU will be presenting The protonmotive force - not merely membrane potential at Bioblast 2022.
- Feb- 22 Tu
- Feb- 23 We
- ALAS project partner Thomas Roach will present Oxidative stress in photosynthesis at Bioblast 2022.
- -»Bioblast 2022« , »ALAS«
- ALAS project partner Thomas Roach will present Oxidative stress in photosynthesis at Bioblast 2022.
- Feb- 24 Th
- Industry partner Incyton will be at Bioblast 2022 with a talk on Long-term monitoring of respiration and morphology of cultured cells.
- -»Bioblast 2022« , »Incyton«
- Industry partner Incyton will be at Bioblast 2022 with a talk on Long-term monitoring of respiration and morphology of cultured cells.
- Feb- 25 Fr
Jan 2022
2022 Week 1
- Jan- 03 Mo
- Jan- 04 Tu
Do you know which graph layout to choose in DatLab?
Different layouts are required depending on which instrumental quality control or measurement with biological sample is performed. Learn more about Standard layouts provided in DatLab:
- »Layout for DatLab graphs«
- communicated by »Schmitt Sabine« and »Komlodi Timea«
- Jan- 05 We
- Jan- 06 Th
- Jan- 07 Fr
Oxia: O2 regime controller for HyperOxia to HypOxia in the O2k
- » Learn more here «
2022 Week 2
- Jan- 10 Mo
Oroboros Instruments supports Bioenergetics Communications.
- » We have signed the Declaration on Research Assessment DORA. «
- Jan- 11 Tu
- Jan- 12 We
- Jan- 13 Th
- Jan- 14 Fr
2022 Week 3
- Jan- 17 Mo
'Assuming a publication charge of € 1200 per article, scientists mentioning mitochondria or photosynthesis pay € 100 000 every day in 2021 for ‘selling’ their output to publishers ― over € 36 Mill per year. ' - Gnaiger (2021) Editorial Bioenerg Commun
- Jan- 18 Tu
The process of Lewy body formation in Parkinson's Disease induces mitochondrial deficits
- Mahul-Mellier AL, Burtscher J, Maharjan N, Weerens L, Croisier M, Kuttler F, Leleu M, Knott GW, Lashuel HA (2020) The process of Lewy body formation, rather than simply α-synuclein fibrillization, is one of the major drivers of neurodegeneration. Proc Natl Acad Sci U S A 117:4971-82. Mahul-Mellier 2020 Proc Natl Acad Sci U S A
- from the O2k-Network »CH Lausanne Place N«
- Jan- 19 We
Elsevier bought Pergamon Press in 1991 for £440m (£919m today) from Robert Maxwell. R Maxwell may be known in relation to financial scandals and to his daughter Ghislaine Maxwell who was convicted on 2021-12-29 linked to several federal crimes including her involvement in a sex-trafficking ring with Jeffrey Epstein, to who's former friends belonged British Prince Andrew, former Prime Minister Tony Blair, or ex-US-presidents Bill Clinton and Donald Trump. Due to paywall journals, Open Access in science remains an unfulfilled dream. - Gnaiger (2021) Editorial BEC Living Communication (2022-01-04)
- Jan- 20 Th
The Q-Module of the NextGen O2k enables electrochemical monitoring of the redox state of the ETS-reactive coenzyme Q pool.
- » Learn more here «
- Jan- 21 Fr
'The burden of responsibilities for an urgent change of the academic publishing ecosystem and scientific communication culture must be shared between the shoulders of individual scientists, the backbone of scientific institutions, and the neurology of governmental regulations and funding agencies.' - Gnaiger (2021) Editorial Bioenerg Commun
2022 Week 4
- Jan- 24 Mo
Oroboros Instruments presents the NextGen-O2k Q-Module at the Q10 Conference: - »10th Conference of the International Coenzyme Q10 Association 2022 Hamburg DE« May 12-15
- - Poster deadline has been extended to the 6th of February
- Jan- 25 Tu
From preprint to journal publication:
- Fischer C, Volani C, Komlódi T, Seifert M, Demetz E, Valente de Souza L, Auer K, Petzer V, von Raffay L, Moser P, Gnaiger E, Weiss G (2021) Dietary iron overload and Hfe-/- related hemochromatosis alter hepatic mitochondrial function. Antioxidants 10:1818. doi.org/10.3390/antiox10111818
- from the O2k-Network »AT Innsbruck Oroboros«
- Jan- 26 We
Measure photosynthesis and light enhanced dark respiration with the PB-Module of the NextGen O2k.
- » Learn more here «
- Jan- 27 Th
- Jan- 28 Fr
Stay alert
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