HU Budapest Tretter L

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HU Budapest Tretter L

OROBOROS O2k-Network

O2k-Network Lab Department of Medical Biochemistry

Semmelweis University

Power-O2k Network Cluster: HU Budapest Semmelweis Univ

Address 37-47. Tuzolto Str., HU-1088
City Budapest
Country Hungary
Weblink Medical Biochemistry
Contact Tretter Laszlo
Team Horvath Gergoe, Komlodi Timea, Nagy Adam
Team previous Kiss Gergely, Konrad Csaba, Szarvas Nikolett
Status 2 Power-O2k 2008-
OROBOROS Events MiP2014, MiP2013, IOC66, IOC62
Topics Hydrogen peroxide, Synaptosomes, Guinea pigs, Mitochondrion, Reactive oxygen species, Oxidative stress


Published Reference
Nemeth 2016 FASEB J 2016 Németh B, Doczi J, Csete D, Kacso G, Ravasz D, Adams D, Kiss G, Nagy AM, Horvath G, Tretter L, Mócsai A, Csépányi-Kömi R, Iordanov I, Adam-Vizi V, Chinopoulos C (2016) Abolition of mitochondrial substrate-level phosphorylation by itaconic acid produced by LPS-induced Irg1 expression in cells of murine macrophage lineage. FASEB J 30:286-300.
Kiss 2014 FASEB J 2014 Kiss G, Konrad C, Pour-Ghaz I, Mansour JJ, Németh B, Starkov AA, Adam-Vizi V, Chinopoulos C (2014) Diaphorases provide NAD+ in anoxia. FASEB J 28:1682-97.
Tretter 2014 Free Radic Biol Med 2014 Tretter L, Horvath G, Hölgyesi A, Essek F, Adam-Vizi V (2014) Enhanced hydrogen peroxide generation accompanies the beneficial bioenergetic effects of methylene blue in isolated brain mitochondria. Free Radic Biol Med 77:317-30.
Tretter 2012 Free Radic Biol Med 2012 Tretter L, Adam-Vizi V (2012) High Ca2+ load promotes hydrogen peroxide generation via activation of α-glycerophosphate dehydrogenase in brain mitochondria. Free Radic Biol Med 53:2119-30.
Komary 2010 Biochim Biophys Acta 2010 Komary Z, Tretter L, Adam-Vizi V (2010) Membrane potential-related effect of calcium on reactive oxygen species generation in isolated brain mitochondria. Biochim Biophys Acta 1797:922-8.


Published Reference
Doerrier 2015 Abstract MiPschool Greenville 2015 2015 "Succinate paradox" study by high resolution respirometry combined with fluorometry and spectrofluorometry: NextGen-O2k.
Doerrier 2015 Abstract MiP2015 2015 Simultaneous measurement of mitochondrial respiration, hydrogen peroxide production, and NADH autofluorescence to assess mitochondrial function.
Komlodi 2014 Abstract MiP2014 2014 Methylenblue, an enhancer of mitochondrial substrate-level phosphorylation.
Tretter 2014 Abstract MiP2014 2014 Cool or heat? Bioenergetic and ROS homeostatic approach to therapeutic hypothermia.
Nagy 2014 Abstract MiP2014 2014 Investigation of the energy metabolism of microglial cells.
Tretter 2013 Abstract MiP2013 2013 Tretter L, Komlódi T, Ádám-Vizi V (2013) The effects of methylmalonic acid on alpha-ketoglutarate supported oxidation in isolated brain, heart and liver mitochondria. Mitochondr Physiol Network 18.08.
Horvath 2012 Abstract Bioblast 2012 Horvath G, Eigentler A, Gnaiger E, Tretter L (2012) Respiratory substrate effects on mitochondrial membrane potential - experiments with mouse cardiac muscle homogenate. Mitochondr Physiol Network 17.12.
Fasching 2011 Abstract Berlin 2011 Fasching M, Harrison DK, Tretter L, Gnaiger E (2011) Combination of high-resolution respirometry and fluorometry for continuous monitoring of hydrogen peroxide production by mitochondria with resolution in the nanomolar range. Abstract Berlin.


Cooperation Semmelweis University Budapest and Medical University of Innsbruck (Nov 2010 and May 2011).


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