MiP2014 Programme

MiP2014

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A1: From genotype to mitochondrial phenotypes in health and disease

	Event	Has title	MiP area	Mammal and model	Tissue and cell	Stress	Pathology
Pesta 2014 Abstract MiP 2014	A1 Oral	Dysregulation of muscle ATP synthesis in hypophosphatemic mouse models and in a patient with hypophosphatemia due to a mutation in NaPi2c.	Exercise physiology;nutrition;life style Patients	Human Mouse	Skeletal muscle		Diabetes
Picard 2014 Abstract MiP2014	A1 Oral	Quantitative regulation of nuclear gene expression by mitochondrial DNA heteroplasmy.	mtDNA;mt-genetics mt-Medicine Patients		Other cell lines
Wojtala 2014 Abstract MiP2014	A1 P-flash	Proteomic analysis of mitochondrial Complex I deficient mouse model - impact of Complex I deficiency on p66Shc-Ser36 phosphorylation pathway in NDUFS4-/- mouse tissues.		Mouse		Oxidative stress;RONS
Zapisek 2014 Abstract MiP2014	A1 Poster	YER077C encodes a novel PPR protein essential for mitochondrial genome expression in Saccharomyces cerevisiae.	mtDNA;mt-genetics	Saccharomyces cerevisiae
Balazova 2014 Abstract MiP2014	A1 Poster	Balanced ratio of anionic mitochondrial phospholipids is important for mitochondrial functions in the yeast Saccharomyces cerevisiae.	Respiration	Saccharomyces cerevisiae		Temperature
Eide 2014 Abstract MiP2014	A1 Oral	Reversible mitochondrial DNA mutagenesis.	mtDNA;mt-genetics	Human	Nervous system Stem cells		Aging;senescence
Holmstroem 2014 Abstract MiP2014	A1 Oral	Homozygous missense mutation in the human NARS2 gene results in reduced homodimerization of mitochondrial AsnRS enzyme in a patient with Alpers syndrome.	mtDNA;mt-genetics mt-Medicine Patients	Human	Fibroblast		Neurodegenerative
Houstek 2014 Abstract MiP2014	A1 Poster	Alteration of structure and function of ATP synthase and cytochrome c oxidase by lack of Fo-a and Cox3 subunits caused by mitochondrial DNA 9205delTA mutation.	mtDNA;mt-genetics mt-Medicine Patients
Kowaltowski 2014 Abstract MiP2014	A1 Oral	Luévano-Martínez LA, Forni FM, dos Santos VT, Souza-Pinto NC, Kowaltowski AJ (2014) Cardiolipin is a key determinant for mitochondrial DNA stability and segregation.	Respiration mt-Membrane mtDNA;mt-genetics	Saccharomyces cerevisiae		Temperature
Kruszewski 2014 Abstract MiP2014	A1 P-flash	Complementation of nuclear-encoded proteins which maintain mitochondrial DNA in S. cerevisiae with homologous proteins from other fungi species.	mtDNA;mt-genetics	Saccharomyces cerevisiae Fungi

A2: Mitochondrial structure and function: fission and fusion to supercomplexes

	Event	Has title	MiP area	Mammal and model	Tissue and cell	Stress	Pathology
Cherubini 2014 Abstract MiP2014	A2 P-flash	Striatal deregulation of Cdk5 alters mitochondrial dynamics in Huntington’s disease.	mt-Structure;fission;fusion		Nervous system	Mitochondrial disease	Neurodegenerative
Mahdaviani 2014 Abstract MiP2014	A2 Oral	Hormone‐induced mitochondrial fission is utilized by brown adipocytes as an amplification pathway for energy expenditure.	Respiration mt-Structure;fission;fusion mt-Membrane	Mouse	Fat Other cell lines
Shirihai 2014 Abstract MiP2014	A2 Oral	Mitochondrial dynamics and quality control, a conflict of interest.	Respiration mt-Structure;fission;fusion Patients	Human	Fat		Aging;senescence Diabetes Obesity
Trudeau 2014 Abstract MiP2014	A2 P-flash	Role of mitochondrial fusion and motility in distributing young mitochondrial protein and removing old protein from the mitochondrial network.	mt-Structure;fission;fusion
Zorzano 2014 Abstract MiP2014	A2 Oral	Metabolic implications of mitofusin 2 dysfunction.	Respiration mt-Structure;fission;fusion Exercise physiology;nutrition;life style	Mouse	Skeletal muscle		Diabetes Obesity
Jezek 2014 Abstract MiP2014	A2 Oral	Mitochondrial cristae morphology changes: from Hackenbrock to hypoxia.	Respiration mt-Structure;fission;fusion mt-Membrane		Other cell lines	Ischemia-reperfusion
Koopman 2014 Abstract MiP2014	A2 Oral	Redox regulation of mitochondrial dynamics and function.	mt-Structure;fission;fusion mtDNA;mt-genetics			Oxidative stress;RONS