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MiP2014

IUBMB - International Union of Biochemistry and Molecular Biology
MiPsociety

MiP2014 - 10th MiPconference

Joint IUBMB/MiP Symposium on Mitochondrial Physiology - Methods, Concepts and Biomedical Perspectives

International Union of Biochemistry and Molecular Biology and Mitochondrial Physiology Society

Obergurgl, Tyrol, Austria. 2014-Sep-08 to 12
MiPArt by Odra Noel


Contents


» MiP2014 Book of Abstracts Open Access
» MiP2014 Abstracts in the MiPMap - sort by MiPareas, species, tissues, respiratory states, diseases, ..*
» MiP2014 Photos
» MiP2014 Feedback


MiP2014: Abstracts - alphabetical order

Presentation Session
Alberici 2014 Abstract MiP2014 Effects of long-chain acyl-CoA synthetase 6 knockdown in primary skeletal muscle cells metabolism. C3
Poster
Ali 2014 Abstract MiP2014 Oxygen-consuming and ROS-producing activities in synaptosomes. B4
Oral
Amoedo 2014 Abstract MiP2014 The metabolic panorama during tumor progression towards malignancy. B3
Oral
Balazova 2014 Abstract MiP2014 Balanced ratio of anionic mitochondrial phospholipids is important for mitochondrial functions in the yeast Saccharomyces cerevisiae. A1
Poster
Borutaite 2014 Abstract MiP2014 Controversies regarding cytochrome c test for mitochondrial membrane integrity. C2
Oral
Bresciani Martins de Andrade 2014 Abstract MiP2014 Mitochondrial function in white adipose tissue: palmitoleic acid (C16:1n7) treatment enhances white adipocyte oxygen consumption. A4
Oral
Bristot 2014 Abstract MiP2014 High-resolution respirometry and bioenergetics evaluation in fibroblasts derived from patients with TP53 germline mutations. C1
Oral
Brown DA 2014 Abstract MiP2014 The cardiolipin-targeting peptide Bendavia preserves post-ischemic mitochondrial energetics by sustaining respiratory supercomplexes. C3
Oral
Brown G 2014 Abstract MiP2014 Complex I inhibition in microglia and inflammatory neuronal loss. C1
Oral
Burtscher 2014 Abstract MiP2014 Region-specific differences in Complex I- and Complex II-linked respiration in the mouse brain. A4
Oral
Cherubini 2014 Abstract MiP2014 Striatal deregulation of Cdk5 alters mitochondrial dynamics in Huntington’s disease. A2
P-flash
Coen 2014 Abstract MiP2014 Exercise improves insulin sensitivity and muscle mitochondrial respiration following Roux-en-Y gastric bypass surgery. A3
Oral
Contreras-Ferrat 2014 Abstract MiP2014 Insulin increases mitochondrial calcium levels regulating both mitochondrial function and intracellular signaling in muscle; this effect is disrupted in fibers from short-term high fat diet fed mice. Mitochondr Physiol Network 19.13. C3
Oral
Dohlmann 2014 Abstract MiP2014 Mitochondrial adaptations to high-intensity training in young and elderly men and women. A3
Oral
Eggimann 2014 Abstract MiP2014 Adaptation to nutrient availability in human fibroblasts with mitochondrial dysfunction: the role of sirtuins. C1
Oral
Eide 2014 Abstract MiP2014 Reversible mitochondrial DNA mutagenesis. A1
Oral
El-Bacha 2014 Abstract MiP2014 Cytotoxicity of grape pomace extract (Vitis vinifera L.) from Brazilian wine industry in human hepatocarcinoma HepG2 cells. C3
Oral
Felser 2014 Abstract MiP2014 Assessing mitochondrial dysfunction in fibroblast cells – a comparison between O2k and multiwell respirometry. B4
Oral
Ferreira 2014 Abstract MiP2014 Impairment of bioenergetic parameters induced by acute carnosine administration in skeletal muscle of young rats. C3
Poster
Figueira 2014 Abstract MiP2014 Mitochondrial respiration and calcium transport in rat tissues: conversely from skeletal muscle, heart and brain, isolated liver mitochondria exhibit gender dimorphism in respiratory activity. C2
Oral
Galina 2014 Abstract MiP2014 Effects of perinatal asphyxia in mitochondria of brain during development of the central nervous system. B3
Oral
Gnaiger 2014 Abstract MiP2014 Cell ergometry: OXPHOS and ETS coupling efficiency. A4
Oral
Gnaiger 2014 Preface MiP2014 MiPArt - Mitchell's equation.
Grefte 2014 Abstract MiP2014 Myotube formation does not require mitochondrial ATP production but is inhibited by rotenone via the Rho-associated, coiled-coil containing protein kinase II. B3
P-flash
Hahn 2014 Abstract MiP2014 Validation of oxygen consumption measurements in muscle and fibroblasts from patients with mitochondrial diseases. C1
Poster
Harrison 2014 Abstract MiP2014 The relationship between cytochrome redox state and oxygen consumption in isolated mouse and beef heart mitochondria during hypoxia. B4
Oral
Hepple 2014 Abstract MiP2014 Denervation modulates mitochondrial function when aging muscle atrophy becomes severe: implications for therapeutic intervention. A3
Oral
Herbst 2014 Abstract MiP2014 Analysis of mitochondrial function in multiple brain regions through in situ permeabilization. A4
Oral
Herminghaus 2014 Abstract MiP2014 Severity of polymicrobial sepsis modulates mitochondrial function in rat liver. A4
Poster
Hickey 2014 Abstract MiP2014 Mitochondrial inefficiencies and anoxic ATP hydrolysis capacities in diabetic rat heart. B4
Oral
Holloway 2014 Abstract MiP2014 Acute diet-induced insulin resistance is associated with increased adipose tissue mitochondrial ROS emissions. B2
Oral
Holmstroem 2014 Abstract MiP2014 Homozygous missense mutation in the human NARS2 gene results in reduced homodimerization of mitochondrial AsnRS enzyme in a patient with Alpers syndrome. A1
Oral
Horscroft 2014 Abstract MiP2014 Substrate utilisation in the hypoxic heart: a glycolysis/glucose oxidation mismatch? B3
Oral
Houghton 2014 Abstract MiP2014 The effect of bioactive phenolics on chronic mitochondrial stress associated with the onset of diabetes. B2
Oral
Houstek 2014 Abstract MiP2014 Alteration of structure and function of ATP synthase and cytochrome c oxidase by lack of Fo-a and Cox3 subunits caused by mitochondrial DNA 9205delTA mutation. A1
Poster
Iyer 2014 Abstract MiP2014 Bioenergetics: arts meets gentle science in sickness and in health. C4
Oral
Jaburek 2014 Abstract MiP2014 The role of phospholipase A2γ in the regulation of mitochondrial uncoupling protein 2–dependent antioxidant function. B2
Oral
Jana Prado 2014 Abstract MiP2014 Defining the role of mitochondrial electron transfer Complex I on the modulation of Ca2+ homeostasis: effects of metformin on cancer cell metabolism. Mitochondr Physiol Network 19.13. C3
P-flash
Jezek 2014 Abstract MiP2014 Mitochondrial cristae morphology changes: from Hackenbrock to hypoxia. A2
Oral
Kabir 2014 Abstract MiP2014 Declining follicular reserve triggers mitochondrial pathway of granulosa cell apoptosis and accelerates the rate of follicular decay. C3
Oral
Kandashvili 2014 Abstract MiP2014 Regulation of energy metabolism in human colorectal cancer cells in situ. B3
Poster
Kane 2014 Abstract MiP2014 Assessing mitochondrial lactate oxidation in permeabilized skeletal muscle fibers highlights important experimental considerations: malate concentration and the cytochrome c effect. C2
Oral
Kluckova 2014 Abstract MiP2014 Proximal ubiquinone binding site in mitochondrial respiratory Complex II is a target for vitamin E analog MitoVES, an experimental anti-cancer agent. Mitochondr Physiol Network 19.13. C4
Oral
Komlodi 2014 Abstract MiP2014 Methylenblue, an enhancer of mitochondrial substrate-level phosphorylation. B1
Poster
Koopman 2014 Abstract MiP2014 Redox regulation of mitochondrial dynamics and function. A2
Oral
Kowaltowski 2014 Abstract MiP2014 Luévano-Martínez LA, Forni FM, dos Santos VT, Souza-Pinto NC, Kowaltowski AJ (2014) Cardiolipin is a key determinant for mitochondrial DNA stability and segregation. A1
Oral
Krumschnabel 2014 Abstract MiP2014 Simultaneous high-resolution measurement of mitochondrial respiration and hydrogen peroxide production. B4
Poster
Kruszewski 2014 Abstract MiP2014 Complementation of nuclear-encoded proteins which maintain mitochondrial DNA in S. cerevisiae with homologous proteins from other fungi species. A1
P-flash
Lai 2014 Abstract1 MiP2014 Improved isolation of high quality subsarcolemmal and interfibrillar mitochondria from skeletal muscle. C2
Oral
Lai 2014 Abstract2 MiP2014 Bioenergetic differences between permeabilized red and white fibers of a non-obese model of type II diabetes. C2
Poster
Laner 2014 Abstract MiP2014 Cytochrome c flux control factor as a quality criterion in respiratory OXPHOS analysis in canine permeabilized fibres. C2
Poster
Larsen 2014 Abstract MiP2014 The effect of high intensity training on mitochondrial fat oxidation in skeletal muscle and subcutaneous adipose tissue. A3
Oral
MacDonald 2014 Abstract MiP2014 The mitochondrial enzyme 4-hydroxy-2-oxoglutarate aldolase (HOGA) – involvement in the TCA cycle. B1
Oral
Maddalena 2014 Abstract MiP2014 Experimental considerations for evaluating bioenergetic effects of a mitochondria-targeted compound, TPP-IOA. C3
Poster
Mahdaviani 2014 Abstract MiP2014 Hormone‐induced mitochondrial fission is utilized by brown adipocytes as an amplification pathway for energy expenditure. A2
Oral
Meszaros 2014 Abstract MiP2014 Methodological aspects of assessing mitochondrial function in small intestinal mucosal samples of rats and guinea pigs. C2
Oral
Mracek 2014 Abstract MiP2014 Function of mitochondrial energy provision apparatus is compromised in patients with chronic heart failure. Mitochondr Physiol Network 19.13. C4
P-flash
Nagy 2014 Abstract MiP2014 Investigation of the energy metabolism of microglial cells. C1
Poster
Neufer 2014 Abstract MiP2014 Assessing ATP production and oxygen consumption simultaneously in permeabilized fibers: ATP/O. A4
Oral
Oparka 2014 Abstract MiP2014 Investigation of the mitochondrial functions to understand p66Shc and reactive oxygen species interplay in tumor cells. B2
Oral
Paju 2014 Abstract MiP2014 Characterization of the effects of pro-inflammatory cytokines on energy metabolism in human myoblasts. C1
Oral
Pecina 2014 Abstract MiP2014 Manifestation of mitochondrial disorders of nuclear origin in lymphocytes. C1
Oral
Perry 2014 Abstract MiP2014 Evaluation of critical experimental parameters for assessing mitochondrial bioenergetics in permeabilized myofibres. B1
Oral
Pesta 2014 Abstract MiP 2014 Dysregulation of muscle ATP synthesis in hypophosphatemic mouse models and in a patient with hypophosphatemia due to a mutation in NaPi2c. A1
Oral
Picard 2014 Abstract MiP2014 Quantitative regulation of nuclear gene expression by mitochondrial DNA heteroplasmy. A1
Oral
Power 2014 Abstract MiP2014 The hot heart: cardiac mitochondrial energetics during hyperthermia. C4
Oral
Purhonen 2014 Abstract MiP2014 Effect of ketogenic diet in mouse model of the mitochondrial hepatopathy GRACILE syndrome.
Rodrigues 2014 Abstract MiP2014 Bioenergetics’ traits of tongue cancer metastatic cells. B3
Poster
Roy 2014 Abstract MiP2014 Differential expression of mitochondrial transporter proteins leads to incomplete fatty acid oxidation and insulin resistance in palmitate-treated muscle cells. C3
Oral
Schoepf 2014 Abstract MiP2014 OXPHOS analysis in small prostate biopsies. A4
Oral
Shirihai 2014 Abstract MiP2014 Mitochondrial dynamics and quality control, a conflict of interest. A2
Oral
Skulachev 2014 Abstract MiP2014 Mitochondria are sources, rather than sinks, of reactive oxygen species. Effects of mitochondria-targeted antioxidants. B2
Oral
Sokolova 2014 Abstract MiP2014 Bioenergetic responses to cyclic hypoxia reveal mitochondrial mechanisms of hypoxia tolerance in marine bivalves. B3
Oral
Sparks 2014 Abstract MiP2014 NAMPT remodels substrate metabolism in skeletal muscle. B1
Oral
Spendiff 2014 Abstract MiP2014 Lessons from the master athlete: mitochondrial contributions to aging. A3
Oral
Starkov 2014 Abstract MiP2014 Mitochondria as H2O2 buffering system. B2
Oral
Stiban 2014 Abstract MiP2014 Very long chain ceramides interfere with C16 ceramide-induced channel formation: rheostatic control of apoptosis. C4
Oral
Sumbalova 2014 Abstract MiP2014 Optimization of malate concentration for high-resolution respirometry: mitochondria from rat liver and brain. B1
Oral
Timon-Gomez 2014 Abstract MiP2014 The function of mitochondrial pyruvate carriers in the adaptation of respiration capacity and stress tolerance in yeast. B3
P-flash
Tretter 2014 Abstract MiP2014 Cool or heat? Bioenergetic and ROS homeostatic approach to therapeutic hypothermia. C4
Oral
Trudeau 2014 Abstract MiP2014 Role of mitochondrial fusion and motility in distributing young mitochondrial protein and removing old protein from the mitochondrial network. A2
P-flash
Volodina 2014 Abstract MiP2014 Multipotent stromal cells injection improves rat liver regeneration through activation of mitochondrial functions after subtotal hepatectomy. B1
Oral
Widlund 2014 Abstract MiP2014 Resveratrol as a double edged sword on mitochondrial function. B4
Oral
Wieckowski 2014 Abstract MiP2014 Understanding the utility and limitations of autopsy samples for mitochondrial studies - evaluation of oxidative stress in the central nervous system of patients with diagnosed or highly probable mitochondrial diseases. C4
P-flash
Wohlwend 2014 Abstract MiP2014 Exercise modality specific mitochondrial adaptations in skeletal muscle of elderly people. A3
Oral
Wojtala 2014 Abstract MiP2014 Proteomic analysis of mitochondrial Complex I deficient mouse model - impact of Complex I deficiency on p66Shc-Ser36 phosphorylation pathway in NDUFS4-/- mouse tissues. A1
P-flash
Zapisek 2014 Abstract MiP2014 YER077C encodes a novel PPR protein essential for mitochondrial genome expression in Saccharomyces cerevisiae. A1
Poster
Zorzano 2014 Abstract MiP2014 Metabolic implications of mitofusin 2 dysfunction. A2
Oral


MiPArt by Odra Noel

MiP2014 Programme: Abstracts in sequential sessions

» MiP2014 Programme.pdf
  • Oral = 10 + 5 min: All talks are 10 min plus 5 min discussion. The invited lecturers provide generously an opportunity to a majority of MiPparticipants to present their work orally, from senior scientists to students.
  • P-flash = 5 + 2 min: Flash presentations or poster flashes are 5 min plus 2 min discussion. You may optionally present your work in addition as a poster (please confirm until August 24, if you choose to bring a poster; poster space will be limited).
  • Poster = Poster presentation: Posters are up during the entire conference, providing an excellent opportunity for person-to-person discussions and for integrating your work into discussions in the plenary sessions.


A: Mitochondrial respiratory control

A1: From genotype to mitochondrial phenotypes in health and disease

Tuesday, Sep 09, 08:30-10:00 »Help - Further information - Make full use of the MiPMap
Session Presentation MiP areas Mammals;models Tissues;cells Stress conditions Pathological states
Houstek 2014 Abstract MiP2014 A1
Poster
Alteration of structure and function of ATP synthase and cytochrome c oxidase by lack of Fo-a and Cox3 subunits caused by mitochondrial DNA 9205delTA mutation. mtDNA;mt-genetics
mt-Medicine
Patients
Pesta 2014 Abstract MiP 2014 A1
Oral
Dysregulation of muscle ATP synthesis in hypophosphatemic mouse models and in a patient with hypophosphatemia due to a mutation in NaPi2c. Exercise physiology;nutrition;life style
Patients
Human
Mouse
Skeletal muscle Diabetes
Picard 2014 Abstract MiP2014 A1
Oral
Quantitative regulation of nuclear gene expression by mitochondrial DNA heteroplasmy. mtDNA;mt-genetics
mt-Medicine
Patients
Wojtala 2014 Abstract MiP2014 A1
P-flash
Proteomic analysis of mitochondrial Complex I deficient mouse model - impact of Complex I deficiency on p66Shc-Ser36 phosphorylation pathway in NDUFS4-/- mouse tissues. Mouse Oxidative stress;RONS
Holmstroem 2014 Abstract MiP2014 A1
Oral
Homozygous missense mutation in the human NARS2 gene results in reduced homodimerization of mitochondrial AsnRS enzyme in a patient with Alpers syndrome. mtDNA;mt-genetics
mt-Medicine
Patients
Human Neurodegenerative
Zapisek 2014 Abstract MiP2014 A1
Poster
YER077C encodes a novel PPR protein essential for mitochondrial genome expression in Saccharomyces cerevisiae. mtDNA;mt-genetics Saccharomyces cerevisiae
Eide 2014 Abstract MiP2014 A1
Oral
Reversible mitochondrial DNA mutagenesis. mtDNA;mt-genetics Human Nervous system Aging;senescence
Balazova 2014 Abstract MiP2014 A1
Poster
Balanced ratio of anionic mitochondrial phospholipids is important for mitochondrial functions in the yeast Saccharomyces cerevisiae. Respiration Saccharomyces cerevisiae Temperature
Kowaltowski 2014 Abstract MiP2014 A1
Oral
Luévano-Martínez LA, Forni FM, dos Santos VT, Souza-Pinto NC, Kowaltowski AJ (2014) Cardiolipin is a key determinant for mitochondrial DNA stability and segregation. Respiration
mt-Membrane
mtDNA;mt-genetics
Saccharomyces cerevisiae Temperature
Kruszewski 2014 Abstract MiP2014 A1
P-flash
Complementation of nuclear-encoded proteins which maintain mitochondrial DNA in S. cerevisiae with homologous proteins from other fungi species. mtDNA;mt-genetics Saccharomyces cerevisiae


A2: Mitochondrial structure and function: fission and fusion to supercomplexes

Tuesday, Sep 09, 10:30-12:00 »Help
Session Presentation MiP areas Mammals;models Tissues;cells Stress conditions Pathological states
Cherubini 2014 Abstract MiP2014 A2
P-flash
Striatal deregulation of Cdk5 alters mitochondrial dynamics in Huntington’s disease. mt-Structure;fission;fusion Nervous system Mitochondrial disease Neurodegenerative
Zorzano 2014 Abstract MiP2014 A2
Oral
Metabolic implications of mitofusin 2 dysfunction. Respiration
mt-Structure;fission;fusion
Exercise physiology;nutrition;life style
Mouse Skeletal muscle Diabetes
Obesity
Jezek 2014 Abstract MiP2014 A2
Oral
Mitochondrial cristae morphology changes: from Hackenbrock to hypoxia. Respiration
mt-Structure;fission;fusion
mt-Membrane
Ischemia-reperfusion
Koopman 2014 Abstract MiP2014 A2
Oral
Redox regulation of mitochondrial dynamics and function. mt-Structure;fission;fusion
mtDNA;mt-genetics
Oxidative stress;RONS
Trudeau 2014 Abstract MiP2014 A2
P-flash
Role of mitochondrial fusion and motility in distributing young mitochondrial protein and removing old protein from the mitochondrial network. mt-Structure;fission;fusion
Mahdaviani 2014 Abstract MiP2014 A2
Oral
Hormone‐induced mitochondrial fission is utilized by brown adipocytes as an amplification pathway for energy expenditure. Respiration
mt-Structure;fission;fusion
mt-Membrane
Mouse Fat
Shirihai 2014 Abstract MiP2014 A2
Oral
Mitochondrial dynamics and quality control, a conflict of interest. Respiration
mt-Structure;fission;fusion
Patients
Human Fat Aging;senescence
Diabetes
Obesity


A3: Mitochondrial response to exercise and aging

Tuesday, Sep 09, 15:30-17:00 »Help
Session Presentation MiP areas Mammals;models Tissues;cells Stress conditions Pathological states
Dohlmann 2014 Abstract MiP2014 A3
Oral
Mitochondrial adaptations to high-intensity training in young and elderly men and women. Respiration
Exercise physiology;nutrition;life style
Human Skeletal muscle Aging;senescence
Hepple 2014 Abstract MiP2014 A3
Oral
Denervation modulates mitochondrial function when aging muscle atrophy becomes severe: implications for therapeutic intervention. Respiration
Exercise physiology;nutrition;life style
mt-Medicine
Human Skeletal muscle Cell death
Permeability transition
Oxidative stress;RONS
Mitochondrial disease
Aging;senescence
Spendiff 2014 Abstract MiP2014 A3
Oral
Lessons from the master athlete: mitochondrial contributions to aging. Respiration
mtDNA;mt-genetics
Exercise physiology;nutrition;life style
Human Skeletal muscle Oxidative stress;RONS Aging;senescence
Wohlwend 2014 Abstract MiP2014 A3
Oral
Exercise modality specific mitochondrial adaptations in skeletal muscle of elderly people. Respiration
mt-Biogenesis;mt-density
Exercise physiology;nutrition;life style
Human Skeletal muscle Aging;senescence
Larsen 2014 Abstract MiP2014 A3
Oral
The effect of high intensity training on mitochondrial fat oxidation in skeletal muscle and subcutaneous adipose tissue. Respiration
mt-Biogenesis;mt-density
Exercise physiology;nutrition;life style
Human Skeletal muscle
Fat
Obesity
Coen 2014 Abstract MiP2014 A3
Oral
Exercise improves insulin sensitivity and muscle mitochondrial respiration following Roux-en-Y gastric bypass surgery. Respiration
Exercise physiology;nutrition;life style
mt-Medicine
Patients
Human Skeletal muscle Diabetes


A4: Coupling efficiency and mitochondrial respiratory control

Tuesday, Sep 09, 17:30-19:00 »Help
Session Presentation MiP areas Mammals;models Tissues;cells Stress conditions Pathological states
Bresciani Martins de Andrade 2014 Abstract MiP2014 A4
Oral
Mitochondrial function in white adipose tissue: palmitoleic acid (C16:1n7) treatment enhances white adipocyte oxygen consumption. Respiration Fat Diabetes
Obesity
Schoepf 2014 Abstract MiP2014 A4
Oral
OXPHOS analysis in small prostate biopsies. Respiration
Patients
Human Genital Oxidative stress;RONS Cancer
Gnaiger 2014 Abstract MiP2014 A4
Oral
Cell ergometry: OXPHOS and ETS coupling efficiency. Respiration
Neufer 2014 Abstract MiP2014 A4
Oral
Assessing ATP production and oxygen consumption simultaneously in permeabilized fibers: ATP/O. Respiration Mouse Skeletal muscle
Burtscher 2014 Abstract MiP2014 A4
Oral
Region-specific differences in Complex I- and Complex II-linked respiration in the mouse brain. Respiration Mouse Nervous system
Herbst 2014 Abstract MiP2014 A4
Oral
Analysis of mitochondrial function in multiple brain regions through in situ permeabilization. Respiration Mouse Nervous system
Herminghaus 2014 Abstract MiP2014 A4
Poster
Severity of polymicrobial sepsis modulates mitochondrial function in rat liver. Respiration
mt-Medicine
Rat Liver Sepsis


B. Experimental protocols and mitochondrial biochemistry

B1: Experimental regimes in functional studies of mitochondrial preparations

Wednesday, Sep 10, 08:30-10:00 »Help
Session Presentation MiP areas Mammals;models Tissues;cells Stress conditions Pathological states
Komlodi 2014 Abstract MiP2014 B1
Poster
Methylenblue, an enhancer of mitochondrial substrate-level phosphorylation. Respiration Guinea pig Nervous system Ischemia-reperfusion Alzheimer's
Parkinson's
MacDonald 2014 Abstract MiP2014 B1
Oral
The mitochondrial enzyme 4-hydroxy-2-oxoglutarate aldolase (HOGA) – involvement in the TCA cycle. Respiration Rat Heart
Nervous system
Liver
Kidney
Perry 2014 Abstract MiP2014 B1
Oral
Evaluation of critical experimental parameters for assessing mitochondrial bioenergetics in permeabilized myofibres. Respiration
Instruments;methods
Human Skeletal muscle
Sparks 2014 Abstract MiP2014 B1
Oral
NAMPT remodels substrate metabolism in skeletal muscle. Respiration
mt-Biogenesis;mt-density
Exercise physiology;nutrition;life style
Mouse Skeletal muscle
Sumbalova 2014 Abstract MiP2014 B1
Oral
Optimization of malate concentration for high-resolution respirometry: mitochondria from rat liver and brain. Respiration
Instruments;methods
Rat Nervous system
Liver
Volodina 2014 Abstract MiP2014 B1
Oral
Multipotent stromal cells injection improves rat liver regeneration through activation of mitochondrial functions after subtotal hepatectomy. Respiration Rat Liver Oxidative stress;RONS


B2: Are mitochondria sources or sinks of reactive oxygen species?

Wednesday, Sep 10, 10:30-12:00 »Help
Session Presentation MiP areas Mammals;models Tissues;cells Stress conditions Pathological states
Jaburek 2014 Abstract MiP2014 B2
Oral
The role of phospholipase A2γ in the regulation of mitochondrial uncoupling protein 2–dependent antioxidant function. Respiration Islet cell;pancreas;thymus Oxidative stress;RONS Diabetes
Starkov 2014 Abstract MiP2014 B2
Oral
Mitochondria as H2O2 buffering system. Oxidative stress;RONS
Holloway 2014 Abstract MiP2014 B2
Oral
Acute diet-induced insulin resistance is associated with increased adipose tissue mitochondrial ROS emissions. Respiration
Exercise physiology;nutrition;life style
Mouse Fat Oxidative stress;RONS Diabetes
Obesity
Houghton 2014 Abstract MiP2014 B2
Oral
The effect of bioactive phenolics on chronic mitochondrial stress associated with the onset of diabetes. Respiration
Exercise physiology;nutrition;life style
Human Liver Oxidative stress;RONS Diabetes
Oparka 2014 Abstract MiP2014 B2
Oral
Investigation of the mitochondrial functions to understand p66Shc and reactive oxygen species interplay in tumor cells. Respiration Human Oxidative stress;RONS Cancer
Skulachev 2014 Abstract MiP2014 B2
Oral
Mitochondria are sources, rather than sinks, of reactive oxygen species. Effects of mitochondria-targeted antioxidants. mt-Membrane
mt-Medicine
Patients
Mouse
Rat
Oxidative stress;RONS Aging;senescence
Inherited


B3: Hypoxia, respiration and fermentation - mitochondrial physiology in cellular energetics

Wednesday, Sep 10, 15:30-17:00 »Help
Session Presentation MiP areas Mammals;models Tissues;cells Stress conditions Pathological states
Amoedo 2014 Abstract MiP2014 B3
Oral
The metabolic panorama during tumor progression towards malignancy. Respiration Cancer
Horscroft 2014 Abstract MiP2014 B3
Oral
Substrate utilisation in the hypoxic heart: a glycolysis/glucose oxidation mismatch? Respiration Rat Heart Ischemia-reperfusion
Sokolova 2014 Abstract MiP2014 B3
Oral
Bioenergetic responses to cyclic hypoxia reveal mitochondrial mechanisms of hypoxia tolerance in marine bivalves. Respiration
Comparative MiP;environmental MiP
Ischemia-reperfusion
Oxidative stress;RONS
Rodrigues 2014 Abstract MiP2014 B3
Poster
Bioenergetics’ traits of tongue cancer metastatic cells. Respiration
mt-Biogenesis;mt-density
Mouse Cancer
Galina 2014 Abstract MiP2014 B3
Oral
Effects of perinatal asphyxia in mitochondria of brain during development of the central nervous system. Respiration
mt-Membrane
Developmental biology
Rat Nervous system Ischemia-reperfusion
Permeability transition
Kandashvili 2014 Abstract MiP2014 B3
Poster
Regulation of energy metabolism in human colorectal cancer cells in situ. Respiration
mt-Membrane
Human Endothelial;epithelial;mesothelial cell Cancer
Timon-Gomez 2014 Abstract MiP2014 B3
P-flash
The function of mitochondrial pyruvate carriers in the adaptation of respiration capacity and stress tolerance in yeast. Respiration
Comparative MiP;environmental MiP
Saccharomyces cerevisiae Oxidative stress;RONS
Grefte 2014 Abstract MiP2014 B3
P-flash
Myotube formation does not require mitochondrial ATP production but is inhibited by rotenone via the Rho-associated, coiled-coil containing protein kinase II. Respiration
Genetic knockout;overexpression
Developmental biology
Mouse Skeletal muscle Oxidative stress;RONS


B4: Instrumental platforms: developments and applications in mitochondrial physiology

Wednesday, Sep 10, 17:30-19:00 »Help
Session Presentation MiP areas Mammals;models Tissues;cells Stress conditions Pathological states
Widlund 2014 Abstract MiP2014 B4
Oral
Resveratrol as a double edged sword on mitochondrial function. Respiration
Pharmacology;toxicology
Ali 2014 Abstract MiP2014 B4
Oral
Oxygen-consuming and ROS-producing activities in synaptosomes. Respiration
Instruments;methods
Nervous system Oxidative stress;RONS
Harrison 2014 Abstract MiP2014 B4
Oral
The relationship between cytochrome redox state and oxygen consumption in isolated mouse and beef heart mitochondria during hypoxia. Respiration Rat
Bovines
Heart
Hickey 2014 Abstract MiP2014 B4
Oral
Mitochondrial inefficiencies and anoxic ATP hydrolysis capacities in diabetic rat heart. Respiration
mt-Membrane
Rat Heart Ischemia-reperfusion
Oxidative stress;RONS
Cardiovascular
Diabetes
Myopathy
Felser 2014 Abstract MiP2014 B4
Oral
Assessing mitochondrial dysfunction in fibroblast cells – a comparison between O2k and multiwell respirometry. Respiration Human Endothelial;epithelial;mesothelial cell
Krumschnabel 2014 Abstract MiP2014 B4
Poster
Simultaneous high-resolution measurement of mitochondrial respiration and hydrogen peroxide production. Respiration Mouse Nervous system Oxidative stress;RONS


C: Functional diagnosis to intervention

C1: Blood cells and cultured cells as models for diagnosis of mitochondrial pathologies

Thursday, Sep 11, 08:30-10:00 »Help
Session Presentation MiP areas Mammals;models Tissues;cells Stress conditions Pathological states
Brown G 2014 Abstract MiP2014 C1
Oral
Complex I inhibition in microglia and inflammatory neuronal loss. Nervous system Oxidative stress;RONS Aging;senescence
Parkinson's
Pecina 2014 Abstract MiP2014 C1
Oral
Manifestation of mitochondrial disorders of nuclear origin in lymphocytes. Respiration
mt-Medicine
Patients
Human Blood cells
Nagy 2014 Abstract MiP2014 C1
Poster
Investigation of the energy metabolism of microglial cells. Respiration Human Nervous system
Eggimann 2014 Abstract MiP2014 C1
Oral
Adaptation to nutrient availability in human fibroblasts with mitochondrial dysfunction: the role of sirtuins. Respiration
mt-Medicine
Patients
Human Mitochondrial disease
Bristot 2014 Abstract MiP2014 C1
Oral
High-resolution respirometry and bioenergetics evaluation in fibroblasts derived from patients with TP53 germline mutations. Respiration
nDNA;cell genetics
mt-Medicine
Human Oxidative stress;RONS Cancer
Hahn 2014 Abstract MiP2014 C1
Poster
Validation of oxygen consumption measurements in muscle and fibroblasts from patients with mitochondrial diseases. Respiration
mt-Medicine
Patients
Human Skeletal muscle Mitochondrial disease
Paju 2014 Abstract MiP2014 C1
Oral
Characterization of the effects of pro-inflammatory cytokines on energy metabolism in human myoblasts. Respiration
Patients
Human Skeletal muscle Aging;senescence


C2: Integrity of mitochondrial preparations and experimental quality control

Thursday, Sep 11, 10:30-12:00 »Help
Session Presentation MiP areas Mammals;models Tissues;cells Stress conditions Pathological states
Laner 2014 Abstract MiP2014 C2
Poster
Cytochrome c flux control factor as a quality criterion in respiratory OXPHOS analysis in canine permeabilized fibres. Respiration Dog Skeletal muscle
Figueira 2014 Abstract MiP2014 C2
Oral
Mitochondrial respiration and calcium transport in rat tissues: conversely from skeletal muscle, heart and brain, isolated liver mitochondria exhibit gender dimorphism in respiratory activity. Respiration
Gender
Rat Heart
Skeletal muscle
Nervous system
Liver
Permeability transition
Borutaite 2014 Abstract MiP2014 C2
Oral
Controversies regarding cytochrome c test for mitochondrial membrane integrity. Respiration
mt-Membrane
Rat Heart
Nervous system
Ischemia-reperfusion
Permeability transition
Kane 2014 Abstract MiP2014 C2
Oral
Assessing mitochondrial lactate oxidation in permeabilized skeletal muscle fibers highlights important experimental considerations: malate concentration and the cytochrome c effect. Respiration Rat Skeletal muscle
Lai 2014 Abstract1 MiP2014 C2
Oral
Improved isolation of high quality subsarcolemmal and interfibrillar mitochondria from skeletal muscle. Respiration Rat
Dog
Heart
Skeletal muscle
Lai 2014 Abstract2 MiP2014 C2
Poster
Bioenergetic differences between permeabilized red and white fibers of a non-obese model of type II diabetes. Respiration
mt-Biogenesis;mt-density
Exercise physiology;nutrition;life style
Rat Skeletal muscle Diabetes
Obesity
Meszaros 2014 Abstract MiP2014 C2
Oral
Methodological aspects of assessing mitochondrial function in small intestinal mucosal samples of rats and guinea pigs. Respiration
Instruments;methods
Rat
Guinea pig


C3: Physiological and pharmacological intervention with mitochondrial function

Thursday, Sep 11, 13:30-15:00 »Help
Session Presentation MiP areas Mammals;models Tissues;cells Stress conditions Pathological states
Ferreira 2014 Abstract MiP2014 C3
Poster
Impairment of bioenergetic parameters induced by acute carnosine administration in skeletal muscle of young rats. Rat Skeletal muscle Inherited
Contreras-Ferrat 2014 Abstract MiP2014 C3
Oral
Insulin increases mitochondrial calcium levels regulating both mitochondrial function and intracellular signaling in muscle; this effect is disrupted in fibers from short-term high fat diet fed mice. Mitochondr Physiol Network 19.13. Exercise physiology;nutrition;life style Mouse Skeletal muscle Diabetes
Alberici 2014 Abstract MiP2014 C3
Poster
Effects of long-chain acyl-CoA synthetase 6 knockdown in primary skeletal muscle cells metabolism. Respiration
Genetic knockout;overexpression
Rat Skeletal muscle Oxidative stress;RONS Diabetes
Obesity
Brown DA 2014 Abstract MiP2014 C3
Oral
The cardiolipin-targeting peptide Bendavia preserves post-ischemic mitochondrial energetics by sustaining respiratory supercomplexes. Respiration
mt-Membrane
Pharmacology;toxicology
Rat Heart Ischemia-reperfusion
El-Bacha 2014 Abstract MiP2014 C3
Oral
Cytotoxicity of grape pomace extract (Vitis vinifera L.) from Brazilian wine industry in human hepatocarcinoma HepG2 cells. Respiration
Pharmacology;toxicology
Human Liver Cell death Cancer
Jana Prado 2014 Abstract MiP2014 C3
P-flash
Defining the role of mitochondrial electron transfer Complex I on the modulation of Ca2+ homeostasis: effects of metformin on cancer cell metabolism. Mitochondr Physiol Network 19.13. Respiration
mt-Membrane
Pharmacology;toxicology
Cancer
Diabetes
Kabir 2014 Abstract MiP2014 C3
Oral
Declining follicular reserve triggers mitochondrial pathway of granulosa cell apoptosis and accelerates the rate of follicular decay. mt-Membrane
Developmental biology
Rat Genital Cell death
Maddalena 2014 Abstract MiP2014 C3
Poster
Experimental considerations for evaluating bioenergetic effects of a mitochondria-targeted compound, TPP-IOA. Respiration
Pharmacology;toxicology
Cell death
Roy 2014 Abstract MiP2014 C3
Oral
Differential expression of mitochondrial transporter proteins leads to incomplete fatty acid oxidation and insulin resistance in palmitate-treated muscle cells. nDNA;cell genetics
Exercise physiology;nutrition;life style
Rat Skeletal muscle Diabetes


C4: Diagnosis and prevention of mitochondrial dysfunction

Thursday, Sep 11, 15:30-17:00 »Help
Session Presentation MiP areas Mammals;models Tissues;cells Stress conditions Pathological states
Kluckova 2014 Abstract MiP2014 C4
Oral
Proximal ubiquinone binding site in mitochondrial respiratory Complex II is a target for vitamin E analog MitoVES, an experimental anti-cancer agent. Mitochondr Physiol Network 19.13. Respiration
mtDNA;mt-genetics
Cell death
Oxidative stress;RONS
Cancer
Iyer 2014 Abstract MiP2014 C4
Oral
Bioenergetics: arts meets gentle science in sickness and in health. Exercise physiology;nutrition;life style
mt-Awareness
Human Obesity
Stiban 2014 Abstract MiP2014 C4
Oral
Very long chain ceramides interfere with C16 ceramide-induced channel formation: rheostatic control of apoptosis. mt-Membrane Cell death
Mracek 2014 Abstract MiP2014 C4
P-flash
Function of mitochondrial energy provision apparatus is compromised in patients with chronic heart failure. Mitochondr Physiol Network 19.13. Respiration
mt-Biogenesis;mt-density
Patients
Human Heart Cardiovascular
Power 2014 Abstract MiP2014 C4
Oral
The hot heart: cardiac mitochondrial energetics during hyperthermia. Respiration Rat Heart Permeability transition
Temperature
Tretter 2014 Abstract MiP2014 C4
Oral
Cool or heat? Bioenergetic and ROS homeostatic approach to therapeutic hypothermia. Respiration
Patients
Guinea pig Nervous system Oxidative stress;RONS
Temperature
Wieckowski 2014 Abstract MiP2014 C4
P-flash
Understanding the utility and limitations of autopsy samples for mitochondrial studies - evaluation of oxidative stress in the central nervous system of patients with diagnosed or highly probable mitochondrial diseases. mt-Medicine Mouse Nervous system Oxidative stress;RONS


» MitoPedia: Respiratory states OXPHOS ETS ROUTINE LEAK - ROX


MitoGlobal Event

Publications in the MiPMap
MiPsociety
IUBMB - International Union of Biochemistry and Molecular Biology
Obergurgl AT, 2014 Sep 08-12. Mitochondrial Physiology Conference MiP2014.

» MiP2014

MiP (2014-09-08) MitoGlobal

Abstract: 10th MiPconference: Joint IUBMB/MiP Symposium on Mitochondrial Physiology - a Point/Counterpoint Meeting, Obergurgl, Austria; with post-conference workshop 95th OROBOROS O2k-Workshop.


Labels: Additional: ORO, 2014 


>> MiP2014 list of participants


>> Location and Venue


>> International programme committee


Sponsors, support and cooperation

IUBMB - International Union of Biochemistry and Molecular Biology

OROBOROS


Hamilton

Hansatech

Stealth peptides.jpg

Tirol Logo CB SAT.jpg

Tourismusverband Obergurgl.jpg


Cooperation


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UMDF LOGO.JPG

MiPsociety





Organizational team
The local organizers acknowledge the assistance by the OROBOROS team: Georg Kandolf, Sandra Fleischmann, Verena Erhart, Karina Fritz
MitoGlobal
Listed under MitoGlobal Events.




Post-conference O2k-Workshop: Organized on the same venue, for hands-on training in mitochondrial respiratory physiology, introducing the combined measurement of high-resolution respirometry and fluorometry (OROBOROS INSTRUMENTS), financially separate from the symposium.
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