MiP2014

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MiP2014

IUBMB - International Union of Biochemistry and Molecular Biology
MiPsociety

MiP2014 - 10th MiPconference

Joint IUBMB/MiP Symposium on Mitochondrial Physiology - Methods, Concepts and Biomedical Perspectives

International Union of Biochemistry and Molecular Biology and Mitochondrial Physiology Society

Obergurgl, Tyrol, Austria. 2014-Sep-08 to 12
MiPArt by Odra Noel


» MiP2014 Book of Abstracts Open Access
» MiP2014 Abstracts in the MiPMap - sort by MiPareas, species, tissues, respiratory states, diseases, ..*
» MiP2014 Photos
» MiP2014 Feedback


MiP2014: Abstracts - alphabetical order

 PresentationSession
Alberici 2014 Abstract MiP2014Effects of long-chain acyl-CoA synthetase 6 knockdown in primary skeletal muscle cells metabolism.C3
Poster
Ali 2014 Abstract MiP2014Oxygen-consuming and ROS-producing activities in synaptosomes.B4
Oral
Amoedo 2014 Abstract MiP2014The metabolic panorama during tumor progression towards malignancy.B3
Oral
Balazova 2014 Abstract MiP2014Balanced ratio of anionic mitochondrial phospholipids is important for mitochondrial functions in the yeast Saccharomyces cerevisiae.A1
Poster
Borutaite 2014 Abstract MiP2014Controversies regarding cytochrome c test for mitochondrial membrane integrity.C2
Oral
Bresciani Martins de Andrade 2014 Abstract MiP2014Mitochondrial function in white adipose tissue: palmitoleic acid (C16:1n7) treatment enhances white adipocyte oxygen consumption.A4
Oral
Bristot 2014 Abstract MiP2014High-resolution respirometry and bioenergetics evaluation in fibroblasts derived from patients with TP53 germline mutations.C1
Oral
Brown DA 2014 Abstract MiP2014The cardiolipin-targeting peptide Bendavia preserves post-ischemic mitochondrial energetics by sustaining respiratory supercomplexes.C3
Oral
Brown G 2014 Abstract MiP2014Complex I inhibition in microglia and inflammatory neuronal loss.C1
Oral
Burtscher 2014 Abstract MiP2014Region-specific differences in Complex I- and Complex II-linked respiration in the mouse brain.A4
Oral
Busch 2014 Abstract MiP2014Mitochondrial fusion and fission dynamics are indispensable for homogenization of inner mitochondrial membrane proteins: insights from superresolution studies.
Cherubini 2014 Abstract MiP2014Striatal deregulation of Cdk5 alters mitochondrial dynamics in Huntington’s disease.A2
P-flash
Coen 2014 Abstract MiP2014Exercise improves insulin sensitivity and muscle mitochondrial respiration following Roux-en-Y gastric bypass surgery.A3
Oral
Contreras-Ferrat 2014 Abstract MiP2014Insulin increases mitochondrial calcium levels regulating both mitochondrial function and intracellular signaling in muscle; this effect is disrupted in fibers from short-term high fat diet fed mice. Mitochondr Physiol Network 19.13.C3
Oral
Dohlmann 2014 Abstract MiP2014Mitochondrial adaptations to high-intensity training in young and elderly men and women.A3
Oral
Eggimann 2014 Abstract MiP2014Adaptation to nutrient availability in human fibroblasts with mitochondrial dysfunction: the role of sirtuins.C1
Oral
Eide 2014 Abstract MiP2014Reversible mitochondrial DNA mutagenesis.A1
Oral
El-Bacha 2014 Abstract MiP2014Cytotoxicity of grape pomace extract (Vitis vinifera L.) from Brazilian wine industry in human hepatocarcinoma HepG2 cells.C3
Oral
Felser 2014 Abstract MiP2014Assessing mitochondrial dysfunction in fibroblast cells – a comparison between O2k and multiwell respirometry.B4
Oral
Ferreira 2014 Abstract MiP2014Impairment of bioenergetic parameters induced by acute carnosine administration in skeletal muscle of young rats.C3
Poster
Figueira 2014 Abstract MiP2014Mitochondrial respiration and calcium transport in rat tissues: conversely from skeletal muscle, heart and brain, isolated liver mitochondria exhibit gender dimorphism in respiratory activity.C2
Oral
Galina 2014 Abstract MiP2014Effects of perinatal asphyxia in mitochondria of brain during development of the central nervous system.B3
Oral
Gnaiger 2014 Abstract MiP2014Cell ergometry: OXPHOS and ETS coupling efficiency.A4
Oral
Gnaiger 2014 Preface MiP2014MiPArt - Mitchell's equation.
Grefte 2014 Abstract MiP2014Myotube formation does not require mitochondrial ATP production but is inhibited by rotenone via the Rho-associated, coiled-coil containing protein kinase II.B3
P-flash
Hahn 2014 Abstract MiP2014Validation of oxygen consumption measurements in muscle and fibroblasts from patients with mitochondrial diseases.C1
Poster
Harrison 2014 Abstract MiP2014The relationship between cytochrome redox state and oxygen consumption in isolated mouse and beef heart mitochondria during hypoxia.B4
Oral
Hepple 2014 Abstract MiP2014Denervation modulates mitochondrial function when aging muscle atrophy becomes severe: implications for therapeutic intervention.A3
Oral
Herbst 2014 Abstract MiP2014Analysis of mitochondrial function in multiple brain regions through in situ permeabilization.A4
Oral
Herminghaus 2014 Abstract MiP2014Severity of polymicrobial sepsis modulates mitochondrial function in rat liver.A4
Poster
Hickey 2014 Abstract MiP2014Mitochondrial inefficiencies and anoxic ATP hydrolysis capacities in diabetic rat heart.B4
Oral
Holloway 2014 Abstract MiP2014Acute diet-induced insulin resistance is associated with increased adipose tissue mitochondrial ROS emissions.B2
Oral
Holmstroem 2014 Abstract MiP2014Homozygous missense mutation in the human NARS2 gene results in reduced homodimerization of mitochondrial AsnRS enzyme in a patient with Alpers syndrome.A1
Oral
Horscroft 2014 Abstract MiP2014Substrate utilisation in the hypoxic heart: a glycolysis/glucose oxidation mismatch?B3
Oral
Houghton 2014 Abstract MiP2014The effect of bioactive phenolics on chronic mitochondrial stress associated with the onset of diabetes.B2
Oral
Houstek 2014 Abstract MiP2014Alteration of structure and function of ATP synthase and cytochrome c oxidase by lack of Fo-a and Cox3 subunits caused by mitochondrial DNA 9205delTA mutation.A1
Poster
Iyer 2014 Abstract MiP2014Bioenergetics: arts meets gentle science in sickness and in health.C4
Oral
Jaburek 2014 Abstract MiP2014The role of phospholipase A2γ in the regulation of mitochondrial uncoupling protein 2–dependent antioxidant function.B2
Oral
Jana Prado 2014 Abstract MiP2014Defining the role of mitochondrial electron transfer Complex I on the modulation of Ca2+ homeostasis: effects of metformin on cancer cell metabolism. Mitochondr Physiol Network 19.13.C3
P-flash
Jezek 2014 Abstract MiP2014Mitochondrial cristae morphology changes: from Hackenbrock to hypoxia.A2
Oral
Kabir 2014 Abstract MiP2014Declining follicular reserve triggers mitochondrial pathway of granulosa cell apoptosis and accelerates the rate of follicular decay.C3
Oral
Kandashvili 2014 Abstract MiP2014Regulation of energy metabolism in human colorectal cancer cells in situ.B3
Poster
Kane 2014 Abstract MiP2014Assessing mitochondrial lactate oxidation in permeabilized skeletal muscle fibers highlights important experimental considerations: malate concentration and the cytochrome c effect.C2
Oral
Kluckova 2014 Abstract MiP2014Proximal ubiquinone binding site in mitochondrial respiratory Complex II is a target for vitamin E analog MitoVES, an experimental anti-cancer agent. Mitochondr Physiol Network 19.13.C4
Oral
Komlodi 2014 Abstract MiP2014Methylenblue, an enhancer of mitochondrial substrate-level phosphorylation.B1
Poster
Koopman 2014 Abstract MiP2014Redox regulation of mitochondrial dynamics and function.A2
Oral
Kowaltowski 2014 Abstract MiP2014Luévano-Martínez LA, Forni FM, dos Santos VT, Souza-Pinto NC, Kowaltowski AJ (2014) Cardiolipin is a key determinant for mitochondrial DNA stability and segregation.A1
Oral
Krumschnabel 2014 Abstract MiP2014Simultaneous high-resolution measurement of mitochondrial respiration and hydrogen peroxide production.B4
Poster
Kruszewski 2014 Abstract MiP2014Complementation of nuclear-encoded proteins which maintain mitochondrial DNA in S. cerevisiae with homologous proteins from other fungi species.A1
P-flash
Lai 2014 Abstract1 MiP2014Improved isolation of high quality subsarcolemmal and interfibrillar mitochondria from skeletal muscle.C2
Oral
Lai 2014 Abstract2 MiP2014Bioenergetic differences between permeabilized red and white fibers of a non-obese model of type II diabetes.C2
Poster
Laner 2014 Abstract MiP2014Cytochrome c flux control factor as a quality criterion in respiratory OXPHOS analysis in canine permeabilized fibres.C2
Poster
Larsen 2014 Abstract MiP2014The effect of high intensity training on mitochondrial fat oxidation in skeletal muscle and subcutaneous adipose tissue.A3
Oral
MacDonald 2014 Abstract MiP2014The mitochondrial enzyme 4-hydroxy-2-oxoglutarate aldolase (HOGA) – involvement in the TCA cycle.B1
Oral
Maddalena 2014 Abstract MiP2014Experimental considerations for evaluating bioenergetic effects of a mitochondria-targeted compound, TPP-IOA.C3
Poster
Mahdaviani 2014 Abstract MiP2014Hormone‐induced mitochondrial fission is utilized by brown adipocytes as an amplification pathway for energy expenditure.A2
Oral
Meszaros 2014 Abstract MiP2014Methodological aspects of assessing mitochondrial function in small intestinal mucosal samples of rats and guinea pigs.C2
Oral
Mracek 2014 Abstract MiP2014Function of mitochondrial energy provision apparatus is compromised in patients with chronic heart failure. Mitochondr Physiol Network 19.13.C4
P-flash
Nagy 2014 Abstract MiP2014Investigation of the energy metabolism of microglial cells.C1
Poster
Neufer 2014 Abstract MiP2014Assessing ATP production and oxygen consumption simultaneously in permeabilized fibers: ATP/O.A4
Oral
Oparka 2014 Abstract MiP2014Investigation of the mitochondrial functions to understand p66Shc and reactive oxygen species interplay in tumor cells.B2
Oral
Paju 2014 Abstract MiP2014Characterization of the effects of pro-inflammatory cytokines on energy metabolism in human myoblasts.C1
Oral
Pecina 2014 Abstract MiP2014Manifestation of mitochondrial disorders of nuclear origin in lymphocytes.C1
Oral
Perry 2014 Abstract MiP2014Evaluation of critical experimental parameters for assessing mitochondrial bioenergetics in permeabilized myofibres.B1
Oral
Pesta 2014 Abstract MiP 2014Dysregulation of muscle ATP synthesis in hypophosphatemic mouse models and in a patient with hypophosphatemia due to a mutation in NaPi2c.A1
Oral
Picard 2014 Abstract MiP2014Quantitative regulation of nuclear gene expression by mitochondrial DNA heteroplasmy.A1
Oral
Power 2014 Abstract MiP2014The hot heart: cardiac mitochondrial energetics during hyperthermia.C4
Oral
Purhonen 2014 Abstract MiP2014Effect of ketogenic diet in mouse model of the mitochondrial hepatopathy GRACILE syndrome.
Rodrigues 2014 Abstract MiP2014Bioenergetics’ traits of tongue cancer metastatic cells.B3
Poster
Roy 2014 Abstract MiP2014Differential expression of mitochondrial transporter proteins leads to incomplete fatty acid oxidation and insulin resistance in palmitate-treated muscle cells.C3
Oral
Schoepf 2014 Abstract MiP2014OXPHOS analysis in small prostate biopsies.A4
Oral
Shirihai 2014 Abstract MiP2014Mitochondrial dynamics and quality control, a conflict of interest.A2
Oral
Skulachev 2014 Abstract MiP2014Mitochondria are sources, rather than sinks, of reactive oxygen species. Effects of mitochondria-targeted antioxidants.B2
Oral
Sokolova 2014 Abstract MiP2014Bioenergetic responses to cyclic hypoxia reveal mitochondrial mechanisms of hypoxia tolerance in marine bivalves.B3
Oral
Sparks 2014 Abstract MiP2014NAMPT remodels substrate metabolism in skeletal muscle.B1
Oral
Spendiff 2014 Abstract MiP2014Lessons from the master athlete: mitochondrial contributions to aging.A3
Oral
Starkov 2014 Abstract MiP2014Mitochondria as H2O2 buffering system.B2
Oral
Stiban 2014 Abstract MiP2014Very long chain ceramides interfere with C16 ceramide-induced channel formation: rheostatic control of apoptosis.C4
Oral
Sumbalova 2014 Abstract MiP2014Optimization of malate concentration for high-resolution respirometry: mitochondria from rat liver and brain.B1
Oral
Timon-Gomez 2014 Abstract MiP2014The function of mitochondrial pyruvate carriers in the adaptation of respiration capacity and stress tolerance in yeast.B3
P-flash
Tretter 2014 Abstract MiP2014Cool or heat? Bioenergetic and ROS homeostatic approach to therapeutic hypothermia.C4
Oral
Trudeau 2014 Abstract MiP2014Role of mitochondrial fusion and motility in distributing young mitochondrial protein and removing old protein from the mitochondrial network.A2
P-flash
Volodina 2014 Abstract MiP2014Multipotent stromal cells injection improves rat liver regeneration through activation of mitochondrial functions after subtotal hepatectomy.B1
Oral
Widlund 2014 Abstract MiP2014Resveratrol as a double edged sword on mitochondrial function.B4
Oral
Wieckowski 2014 Abstract MiP2014Understanding the utility and limitations of autopsy samples for mitochondrial studies - evaluation of oxidative stress in the central nervous system of patients with diagnosed or highly probable mitochondrial diseases.C4
P-flash
Wohlwend 2014 Abstract MiP2014Exercise modality specific mitochondrial adaptations in skeletal muscle of elderly people.A3
Oral
Wojtala 2014 Abstract MiP2014Proteomic analysis of mitochondrial Complex I deficient mouse model - impact of Complex I deficiency on p66Shc-Ser36 phosphorylation pathway in NDUFS4-/- mouse tissues.A1
P-flash
Zapisek 2014 Abstract MiP2014YER077C encodes a novel PPR protein essential for mitochondrial genome expression in Saccharomyces cerevisiae.A1
Poster
Zorzano 2014 Abstract MiP2014Metabolic implications of mitofusin 2 dysfunction.A2
Oral


MiPArt by Odra Noel

MiP2014 Programme: Abstracts in sequential sessions

» MiP2014 Programme.pdf
  • Oral = 10 + 5 min: All talks are 10 min plus 5 min discussion. The invited lecturers provide generously an opportunity to a majority of MiPparticipants to present their work orally, from senior scientists to students.
  • P-flash = 5 + 2 min: Flash presentations or poster flashes are 5 min plus 2 min discussion. You may optionally present your work in addition as a poster (please confirm until August 24, if you choose to bring a poster; poster space will be limited).
  • Poster = Poster presentation: Posters are up during the entire conference, providing an excellent opportunity for person-to-person discussions and for integrating your work into discussions in the plenary sessions.


A: Mitochondrial respiratory control

A1: From genotype to mitochondrial phenotypes in health and disease

Tuesday, Sep 09, 08:30-10:00 »Help - Further information - Make full use of the MiPMap
 SessionPresentationMiP areasMammals;modelsTissues;cellsStress conditionsPathological states
Balazova 2014 Abstract MiP2014A1
Poster
Balanced ratio of anionic mitochondrial phospholipids is important for mitochondrial functions in the yeast Saccharomyces cerevisiae.RespirationSaccharomyces cerevisiae
Eide 2014 Abstract MiP2014A1
Oral
Reversible mitochondrial DNA mutagenesis.mtDNA;mt-geneticsHumanNervous system
Stem cells
Aging;senescence
Pesta 2014 Abstract MiP 2014A1
Oral
Dysregulation of muscle ATP synthesis in hypophosphatemic mouse models and in a patient with hypophosphatemia due to a mutation in NaPi2c.Exercise physiology;nutrition;life style
Patients
Human
Mouse
Skeletal muscleDiabetes
Holmstroem 2014 Abstract MiP2014A1
Oral
Homozygous missense mutation in the human NARS2 gene results in reduced homodimerization of mitochondrial AsnRS enzyme in a patient with Alpers syndrome.mtDNA;mt-genetics
mt-Medicine
Patients
HumanFibroblastNeurodegenerative
Picard 2014 Abstract MiP2014A1
Oral
Quantitative regulation of nuclear gene expression by mitochondrial DNA heteroplasmy.mtDNA;mt-genetics
mt-Medicine
Patients
Other cell lines
Houstek 2014 Abstract MiP2014A1
Poster
Alteration of structure and function of ATP synthase and cytochrome c oxidase by lack of Fo-a and Cox3 subunits caused by mitochondrial DNA 9205delTA mutation.mtDNA;mt-genetics
mt-Medicine
Patients
Wojtala 2014 Abstract MiP2014A1
P-flash
Proteomic analysis of mitochondrial Complex I deficient mouse model - impact of Complex I deficiency on p66Shc-Ser36 phosphorylation pathway in NDUFS4-/- mouse tissues.Mouse
Kowaltowski 2014 Abstract MiP2014A1
Oral
Luévano-Martínez LA, Forni FM, dos Santos VT, Souza-Pinto NC, Kowaltowski AJ (2014) Cardiolipin is a key determinant for mitochondrial DNA stability and segregation.Respiration
mt-Membrane
mtDNA;mt-genetics
Saccharomyces cerevisiae
Zapisek 2014 Abstract MiP2014A1
Poster
YER077C encodes a novel PPR protein essential for mitochondrial genome expression in Saccharomyces cerevisiae.mtDNA;mt-geneticsSaccharomyces cerevisiae
Kruszewski 2014 Abstract MiP2014A1
P-flash
Complementation of nuclear-encoded proteins which maintain mitochondrial DNA in S. cerevisiae with homologous proteins from other fungi species.mtDNA;mt-geneticsSaccharomyces cerevisiae
Fungi

A2: Mitochondrial structure and function: fission and fusion to supercomplexes

Tuesday, Sep 09, 10:30-12:00 »Help
 SessionPresentationMiP areasMammals;modelsTissues;cellsStress conditionsPathological states
Zorzano 2014 Abstract MiP2014A2
Oral
Metabolic implications of mitofusin 2 dysfunction.Respiration
mt-Structure;fission;fusion
Exercise physiology;nutrition;life style
MouseSkeletal muscleDiabetes
Obesity
Jezek 2014 Abstract MiP2014A2
Oral
Mitochondrial cristae morphology changes: from Hackenbrock to hypoxia.Respiration
mt-Structure;fission;fusion
mt-Membrane
Other cell lines
Cherubini 2014 Abstract MiP2014A2
P-flash
Striatal deregulation of Cdk5 alters mitochondrial dynamics in Huntington’s disease.mt-Structure;fission;fusionNervous systemNeurodegenerative
Koopman 2014 Abstract MiP2014A2
Oral
Redox regulation of mitochondrial dynamics and function.mt-Structure;fission;fusion
mtDNA;mt-genetics
Mahdaviani 2014 Abstract MiP2014A2
Oral
Hormone‐induced mitochondrial fission is utilized by brown adipocytes as an amplification pathway for energy expenditure.Respiration
mt-Membrane
mt-Structure;fission;fusion
MouseFat
Other cell lines
Shirihai 2014 Abstract MiP2014A2
Oral
Mitochondrial dynamics and quality control, a conflict of interest.Patients
Respiration
mt-Structure;fission;fusion
HumanFatAging;senescence
Diabetes
Obesity
Trudeau 2014 Abstract MiP2014A2
P-flash
Role of mitochondrial fusion and motility in distributing young mitochondrial protein and removing old protein from the mitochondrial network.mt-Structure;fission;fusion

A3: Mitochondrial response to exercise and aging

Tuesday, Sep 09, 15:30-17:00 »Help
 SessionPresentationMiP areasMammals;modelsTissues;cellsStress conditionsPathological states
Hepple 2014 Abstract MiP2014A3
Oral
Denervation modulates mitochondrial function when aging muscle atrophy becomes severe: implications for therapeutic intervention.Respiration
Exercise physiology;nutrition;life style
mt-Medicine
HumanSkeletal muscleAging;senescence
Larsen 2014 Abstract MiP2014A3
Oral
The effect of high intensity training on mitochondrial fat oxidation in skeletal muscle and subcutaneous adipose tissue.Respiration
mt-Biogenesis;mt-density
Exercise physiology;nutrition;life style
HumanSkeletal muscle
Fat
Obesity
Coen 2014 Abstract MiP2014A3
Oral
Exercise improves insulin sensitivity and muscle mitochondrial respiration following Roux-en-Y gastric bypass surgery.Respiration
Exercise physiology;nutrition;life style
mt-Medicine
Patients
HumanSkeletal muscleDiabetes
Spendiff 2014 Abstract MiP2014A3
Oral
Lessons from the master athlete: mitochondrial contributions to aging.Respiration
mtDNA;mt-genetics
Exercise physiology;nutrition;life style
HumanSkeletal muscleAging;senescence
Wohlwend 2014 Abstract MiP2014A3
Oral
Exercise modality specific mitochondrial adaptations in skeletal muscle of elderly people.Exercise physiology;nutrition;life style
Respiration
mt-Biogenesis;mt-density
HumanSkeletal muscleAging;senescence
Dohlmann 2014 Abstract MiP2014A3
Oral
Mitochondrial adaptations to high-intensity training in young and elderly men and women.Respiration
Exercise physiology;nutrition;life style
HumanSkeletal muscle
HeLa
Fibroblast
Aging;senescence

A4: Coupling efficiency and mitochondrial respiratory control

Tuesday, Sep 09, 17:30-19:00 »Help
 SessionPresentationMiP areasMammals;modelsTissues;cellsStress conditionsPathological states
Gnaiger 2014 Abstract MiP2014A4
Oral
Cell ergometry: OXPHOS and ETS coupling efficiency.Respiration
Herbst 2014 Abstract MiP2014A4
Oral
Analysis of mitochondrial function in multiple brain regions through in situ permeabilization.RespirationMouseNervous system
Bresciani Martins de Andrade 2014 Abstract MiP2014A4
Oral
Mitochondrial function in white adipose tissue: palmitoleic acid (C16:1n7) treatment enhances white adipocyte oxygen consumption.RespirationFatDiabetes
Obesity
Herminghaus 2014 Abstract MiP2014A4
Poster
Severity of polymicrobial sepsis modulates mitochondrial function in rat liver.Respiration
mt-Medicine
RatLiverSepsis
Burtscher 2014 Abstract MiP2014A4
Oral
Region-specific differences in Complex I- and Complex II-linked respiration in the mouse brain.RespirationMouseNervous system
Neufer 2014 Abstract MiP2014A4
Oral
Assessing ATP production and oxygen consumption simultaneously in permeabilized fibers: ATP/O.RespirationMouseSkeletal muscle
Schoepf 2014 Abstract MiP2014A4
Oral
OXPHOS analysis in small prostate biopsies.Respiration
Patients
HumanGenitalCancer

B. Experimental protocols and mitochondrial biochemistry

B1: Experimental regimes in functional studies of mitochondrial preparations

Wednesday, Sep 10, 08:30-10:00 »Help
 SessionPresentationMiP areasMammals;modelsTissues;cellsStress conditionsPathological states
Volodina 2014 Abstract MiP2014B1
Oral
Multipotent stromal cells injection improves rat liver regeneration through activation of mitochondrial functions after subtotal hepatectomy.RespirationRatLiver
Komlodi 2014 Abstract MiP2014B1
Poster
Methylenblue, an enhancer of mitochondrial substrate-level phosphorylation.RespirationGuinea pigNervous systemAlzheimer's
Parkinson's
MacDonald 2014 Abstract MiP2014B1
Oral
The mitochondrial enzyme 4-hydroxy-2-oxoglutarate aldolase (HOGA) – involvement in the TCA cycle.RespirationRatHeart
Nervous system
Liver
Kidney
Perry 2014 Abstract MiP2014B1
Oral
Evaluation of critical experimental parameters for assessing mitochondrial bioenergetics in permeabilized myofibres.Respiration
Instruments;methods
HumanSkeletal muscle
Sparks 2014 Abstract MiP2014B1
Oral
NAMPT remodels substrate metabolism in skeletal muscle.Respiration
mt-Biogenesis;mt-density
Exercise physiology;nutrition;life style
MouseSkeletal muscle
Sumbalova 2014 Abstract MiP2014B1
Oral
Optimization of malate concentration for high-resolution respirometry: mitochondria from rat liver and brain.Respiration
Instruments;methods
RatNervous system
Liver

B2: Are mitochondria sources or sinks of reactive oxygen species?

Wednesday, Sep 10, 10:30-12:00 »Help
 SessionPresentationMiP areasMammals;modelsTissues;cellsStress conditionsPathological states
Houghton 2014 Abstract MiP2014B2
Oral
The effect of bioactive phenolics on chronic mitochondrial stress associated with the onset of diabetes.Respiration
Exercise physiology;nutrition;life style
HumanLiverDiabetes
Jaburek 2014 Abstract MiP2014B2
Oral
The role of phospholipase A2γ in the regulation of mitochondrial uncoupling protein 2–dependent antioxidant function.RespirationIslet cell;pancreas;thymusDiabetes
Holloway 2014 Abstract MiP2014B2
Oral
Acute diet-induced insulin resistance is associated with increased adipose tissue mitochondrial ROS emissions.Respiration
Exercise physiology;nutrition;life style
MouseFatDiabetes
Obesity
Oparka 2014 Abstract MiP2014B2
Oral
Investigation of the mitochondrial functions to understand p66Shc and reactive oxygen species interplay in tumor cells.RespirationHumanCancer
Skulachev 2014 Abstract MiP2014B2
Oral
Mitochondria are sources, rather than sinks, of reactive oxygen species. Effects of mitochondria-targeted antioxidants.mt-Membrane
mt-Medicine
Patients
Mouse
Rat
Aging;senescence
Inherited
Starkov 2014 Abstract MiP2014B2
Oral
Mitochondria as H2O2 buffering system.

B3: Hypoxia, respiration and fermentation - mitochondrial physiology in cellular energetics

Wednesday, Sep 10, 15:30-17:00 »Help
 SessionPresentationMiP areasMammals;modelsTissues;cellsStress conditionsPathological states
Grefte 2014 Abstract MiP2014B3
P-flash
Myotube formation does not require mitochondrial ATP production but is inhibited by rotenone via the Rho-associated, coiled-coil containing protein kinase II.Respiration
Genetic knockout;overexpression
Developmental biology
MouseSkeletal muscle
Galina 2014 Abstract MiP2014B3
Oral
Effects of perinatal asphyxia in mitochondria of brain during development of the central nervous system.Respiration
mt-Membrane
Developmental biology
RatNervous system
Amoedo 2014 Abstract MiP2014B3
Oral
The metabolic panorama during tumor progression towards malignancy.RespirationOther cell linesCancer
Horscroft 2014 Abstract MiP2014B3
Oral
Substrate utilisation in the hypoxic heart: a glycolysis/glucose oxidation mismatch?RespirationRatHeart
Rodrigues 2014 Abstract MiP2014B3
Poster
Bioenergetics’ traits of tongue cancer metastatic cells.Respiration
mt-Biogenesis;mt-density
MouseLymphocyteCancer
Kandashvili 2014 Abstract MiP2014B3
Poster
Regulation of energy metabolism in human colorectal cancer cells in situ.Respiration
mt-Membrane
HumanEndothelial;epithelial;mesothelial cellCancer
Sokolova 2014 Abstract MiP2014B3
Oral
Bioenergetic responses to cyclic hypoxia reveal mitochondrial mechanisms of hypoxia tolerance in marine bivalves.Respiration
Comparative MiP;environmental MiP
Other invertebrates
Timon-Gomez 2014 Abstract MiP2014B3
P-flash
The function of mitochondrial pyruvate carriers in the adaptation of respiration capacity and stress tolerance in yeast.Respiration
Comparative MiP;environmental MiP
Saccharomyces cerevisiae

B4: Instrumental platforms: developments and applications in mitochondrial physiology

Wednesday, Sep 10, 17:30-19:00 »Help
 SessionPresentationMiP areasMammals;modelsTissues;cellsStress conditionsPathological states
Hickey 2014 Abstract MiP2014B4
Oral
Mitochondrial inefficiencies and anoxic ATP hydrolysis capacities in diabetic rat heart.Respiration
mt-Membrane
RatHeartCardiovascular
Diabetes
Myopathy
Krumschnabel 2014 Abstract MiP2014B4
Poster
Simultaneous high-resolution measurement of mitochondrial respiration and hydrogen peroxide production.RespirationMouseNervous system
Ali 2014 Abstract MiP2014B4
Oral
Oxygen-consuming and ROS-producing activities in synaptosomes.Respiration
Instruments;methods
Nervous system
Widlund 2014 Abstract MiP2014B4
Oral
Resveratrol as a double edged sword on mitochondrial function.Respiration
Pharmacology;toxicology
HeLa
Felser 2014 Abstract MiP2014B4
Oral
Assessing mitochondrial dysfunction in fibroblast cells – a comparison between O2k and multiwell respirometry.RespirationHumanEndothelial;epithelial;mesothelial cell
HeLa
Fibroblast
Harrison 2014 Abstract MiP2014B4
Oral
The relationship between cytochrome redox state and oxygen consumption in isolated mouse and beef heart mitochondria during hypoxia.RespirationRat
Bovines
Heart

C: Functional diagnosis to intervention

C1: Blood cells and cultured cells as models for diagnosis of mitochondrial pathologies

Thursday, Sep 11, 08:30-10:00 »Help
 SessionPresentationMiP areasMammals;modelsTissues;cellsStress conditionsPathological states
Pecina 2014 Abstract MiP2014C1
Oral
Manifestation of mitochondrial disorders of nuclear origin in lymphocytes.Respiration
mt-Medicine
Patients
HumanBlood cells
Lymphocyte
Eggimann 2014 Abstract MiP2014C1
Oral
Adaptation to nutrient availability in human fibroblasts with mitochondrial dysfunction: the role of sirtuins.Respiration
mt-Medicine
Patients
HumanFibroblast
Bristot 2014 Abstract MiP2014C1
Oral
High-resolution respirometry and bioenergetics evaluation in fibroblasts derived from patients with TP53 germline mutations.Respiration
nDNA;cell genetics
mt-Medicine
HumanFibroblastCancer
Hahn 2014 Abstract MiP2014C1
Poster
Validation of oxygen consumption measurements in muscle and fibroblasts from patients with mitochondrial diseases.Respiration
mt-Medicine
Patients
HumanSkeletal muscle
Fibroblast
Brown G 2014 Abstract MiP2014C1
Oral
Complex I inhibition in microglia and inflammatory neuronal loss.Nervous systemAging;senescence
Parkinson's
Nagy 2014 Abstract MiP2014C1
Poster
Investigation of the energy metabolism of microglial cells.RespirationHumanNervous system
Paju 2014 Abstract MiP2014C1
Oral
Characterization of the effects of pro-inflammatory cytokines on energy metabolism in human myoblasts.Respiration
Patients
HumanSkeletal muscleAging;senescence


C2: Integrity of mitochondrial preparations and experimental quality control

Thursday, Sep 11, 10:30-12:00 »Help
 SessionPresentationMiP areasMammals;modelsTissues;cellsStress conditionsPathological states
Kane 2014 Abstract MiP2014C2
Oral
Assessing mitochondrial lactate oxidation in permeabilized skeletal muscle fibers highlights important experimental considerations: malate concentration and the cytochrome c effect.RespirationRatSkeletal muscle
Lai 2014 Abstract1 MiP2014C2
Oral
Improved isolation of high quality subsarcolemmal and interfibrillar mitochondria from skeletal muscle.RespirationRat
Dog
Heart
Skeletal muscle
Fibroblast
Borutaite 2014 Abstract MiP2014C2
Oral
Controversies regarding cytochrome c test for mitochondrial membrane integrity.Respiration
mt-Membrane
RatHeart
Nervous system
Lai 2014 Abstract2 MiP2014C2
Poster
Bioenergetic differences between permeabilized red and white fibers of a non-obese model of type II diabetes.Respiration
mt-Biogenesis;mt-density
Exercise physiology;nutrition;life style
RatSkeletal muscleDiabetes
Obesity
Meszaros 2014 Abstract MiP2014C2
Oral
Methodological aspects of assessing mitochondrial function in small intestinal mucosal samples of rats and guinea pigs.Respiration
Instruments;methods
Rat
Guinea pig
Figueira 2014 Abstract MiP2014C2
Oral
Mitochondrial respiration and calcium transport in rat tissues: conversely from skeletal muscle, heart and brain, isolated liver mitochondria exhibit gender dimorphism in respiratory activity.Respiration
Gender
RatHeart
Skeletal muscle
Nervous system
Liver
Laner 2014 Abstract MiP2014C2
Poster
Cytochrome c flux control factor as a quality criterion in respiratory OXPHOS analysis in canine permeabilized fibres.RespirationDogSkeletal muscle

C3: Physiological and pharmacological intervention with mitochondrial function

Thursday, Sep 11, 13:30-15:00 »Help
 SessionPresentationMiP areasMammals;modelsTissues;cellsStress conditionsPathological states
Roy 2014 Abstract MiP2014C3
Oral
Differential expression of mitochondrial transporter proteins leads to incomplete fatty acid oxidation and insulin resistance in palmitate-treated muscle cells.nDNA;cell genetics
Exercise physiology;nutrition;life style
RatSkeletal muscleDiabetes
El-Bacha 2014 Abstract MiP2014C3
Oral
Cytotoxicity of grape pomace extract (Vitis vinifera L.) from Brazilian wine industry in human hepatocarcinoma HepG2 cells.Respiration
Pharmacology;toxicology
HumanLiverCancer
Alberici 2014 Abstract MiP2014C3
Poster
Effects of long-chain acyl-CoA synthetase 6 knockdown in primary skeletal muscle cells metabolism.Respiration
Genetic knockout;overexpression
RatSkeletal muscleDiabetes
Obesity
Ferreira 2014 Abstract MiP2014C3
Poster
Impairment of bioenergetic parameters induced by acute carnosine administration in skeletal muscle of young rats.RatSkeletal muscleInherited
Brown DA 2014 Abstract MiP2014C3
Oral
The cardiolipin-targeting peptide Bendavia preserves post-ischemic mitochondrial energetics by sustaining respiratory supercomplexes.Respiration
mt-Membrane
Pharmacology;toxicology
RatHeart
Jana Prado 2014 Abstract MiP2014C3
P-flash
Defining the role of mitochondrial electron transfer Complex I on the modulation of Ca2+ homeostasis: effects of metformin on cancer cell metabolism. Mitochondr Physiol Network 19.13.Respiration
mt-Membrane
Pharmacology;toxicology
Cancer
Diabetes
Contreras-Ferrat 2014 Abstract MiP2014C3
Oral
Insulin increases mitochondrial calcium levels regulating both mitochondrial function and intracellular signaling in muscle; this effect is disrupted in fibers from short-term high fat diet fed mice. Mitochondr Physiol Network 19.13.Exercise physiology;nutrition;life styleMouseSkeletal muscleDiabetes
Kabir 2014 Abstract MiP2014C3
Oral
Declining follicular reserve triggers mitochondrial pathway of granulosa cell apoptosis and accelerates the rate of follicular decay.mt-Membrane
Developmental biology
RatGenital
Maddalena 2014 Abstract MiP2014C3
Poster
Experimental considerations for evaluating bioenergetic effects of a mitochondria-targeted compound, TPP-IOA.Respiration
Pharmacology;toxicology

C4: Diagnosis and prevention of mitochondrial dysfunction

Thursday, Sep 11, 15:30-17:00 »Help
 SessionPresentationMiP areasMammals;modelsTissues;cellsStress conditionsPathological states
Wieckowski 2014 Abstract MiP2014C4
P-flash
Understanding the utility and limitations of autopsy samples for mitochondrial studies - evaluation of oxidative stress in the central nervous system of patients with diagnosed or highly probable mitochondrial diseases.mt-MedicineMouseNervous system
Iyer 2014 Abstract MiP2014C4
Oral
Bioenergetics: arts meets gentle science in sickness and in health.Exercise physiology;nutrition;life style
mt-Awareness
HumanObesity
Mracek 2014 Abstract MiP2014C4
P-flash
Function of mitochondrial energy provision apparatus is compromised in patients with chronic heart failure. Mitochondr Physiol Network 19.13.Respiration
mt-Biogenesis;mt-density
Patients
HumanHeartCardiovascular
Kluckova 2014 Abstract MiP2014C4
Oral
Proximal ubiquinone binding site in mitochondrial respiratory Complex II is a target for vitamin E analog MitoVES, an experimental anti-cancer agent. Mitochondr Physiol Network 19.13.Respiration
mtDNA;mt-genetics
Other cell linesCancer
Power 2014 Abstract MiP2014C4
Oral
The hot heart: cardiac mitochondrial energetics during hyperthermia.RespirationRatHeart
Stiban 2014 Abstract MiP2014C4
Oral
Very long chain ceramides interfere with C16 ceramide-induced channel formation: rheostatic control of apoptosis.mt-Membrane
Tretter 2014 Abstract MiP2014C4
Oral
Cool or heat? Bioenergetic and ROS homeostatic approach to therapeutic hypothermia.Respiration
Patients
Guinea pigNervous system


» MitoPedia: Respiratory states OXPHOS ETS ROUTINE LEAK - ROX


MitoGlobal Event

Publications in the MiPMap
MiPsociety
IUBMB - International Union of Biochemistry and Molecular Biology
Obergurgl AT, 2014 Sep 08-12. Mitochondrial Physiology Conference MiP2014.

» MiP2014

MiP (2014-09-08) MitoGlobal

Abstract: 10th MiPconference: Joint IUBMB/MiP Symposium on Mitochondrial Physiology - a Point/Counterpoint Meeting, Obergurgl, Austria; with post-conference workshop 95th OROBOROS O2k-Workshop.


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Additional: ORO, 2014 


>> MiP2014 list of participants


>> Location and Venue


>> International programme committee


Sponsors, support and cooperation

IUBMB - International Union of Biochemistry and Molecular Biology

OROBOROS


Hamilton

Hansatech

Stealth peptides.jpg

Tirol Logo CB SAT.jpg

Tourismusverband Obergurgl.jpg


Cooperation


MUI logo.png


UMDF LOGO.JPG

MiPsociety





Organizational team
The local organizers acknowledge the assistance by the OROBOROS team: Georg Kandolf, Sandra Fleischmann, Verena Erhart, Karina Fritz
MitoGlobal
Listed under MitoGlobal Events.




Post-conference O2k-Workshop: Organized on the same venue, for hands-on training in mitochondrial respiratory physiology, introducing the combined measurement of high-resolution respirometry and fluorometry (OROBOROS INSTRUMENTS), financially separate from the symposium.