Oroboros Ecosystem Agenda 2022 Archive
- Mitochondria and Cell Research - the Oroboros Ecosystem
Last week
2022 Week 37
- Sep-12 Mo
From the MitoKIN project - preprint to publication:
- Torres-Quesada O, Doerrier C, Strich S, Gnaiger E, Stefan E (2022) Physiological cell culture media tune mitochondrial bioenergetics and drug sensitivity in cancer cell models. https://doi.org/10.3390/cancers14163917
- from the O2k-Network »AT Innsbruck Oroboros«
- Sep-13 Tu
- Sep-14 We
Bioenerg Commun 2022.9:A publication with video presentation from Bioblast 2022: BEC Inaugural Conference
- Posch W, Dichtl S, Zaderer V, Lass-Flörl C, Wilflingseder D (2022) How to optimize respiratory models for SARS-CoV-2 research. https://doi.org/10.26124/bec:2022-0009
- Sep-15 Th - World Lymphoma Awareness Day
OXPHOS as a potential therapeutic target in classical Hodgkin lymphoma
- Birkenmeier K, Droese S, Wittig I, Winkelmann R, Käfer V, Doering C, Hartmann S, Wenz T, Reichert AS, Brandt U, Hansmann ML (2016) Hodgkin and Reed-Sternberg cells of classical Hodgkin lymphoma are highly dependent on oxidative phosphorylation. Int J Cancer 138:2231-46. »Bioblast link«
- from the O2k-Network »DE Frankfurt Droese S«, »DE Frankfurt Wittig I« and »NL Nijmegen Brandt U«
- Sep-16 Fr
- »Europhysiology 2022 Copenhagen DK« Sep 16-18
Sep 2022
- Sep- 01 Th - Leukemia and Lymphoma Awareness Month
Metformin-mediated reduction of mitochondrial activity contributes to decreased cell viability in myeloproliferative neoplasms cells
- Machado-Neto JA, Fenerich BA, Scopim-Ribeiro R, Eide CA, Coelho-Silva JL, Dechandt CRP, Fernandes JC, Rodrigues Alves APN, Scheucher PS, Simões BP, Alberici LC, de Figueiredo Pontes LL, Tognon CE, Druker BJ, Rego EM, Traina F (2018) Metformin exerts multitarget antileukemia activity in JAK2V617F-positive myeloproliferative neoplasms. Cell Death Dis 9:311. »Bioblast link«
- from the O2k-Network »BR Ribeirao Preto Alberici LC«
- Sep-02 Fr
2022 Week 36
- Sep-05 Mo - Prostate Cancer Awareness Month
“Mitochondria of the malignant prostate cells have a higher affinity for succinate and this metabolite supports mitochondrial physiology through the induction of expression and activities of mitochondrial complexes”
- Bastos Sant'Anna Silva AC, Perez-Valencia JA, Sciacovelli M, Lalou C, Sarlak S, Tronci L, Nikitopoulou E, Meszaros AT, Frezza C, Rossignol R, Gnaiger E, Klocker H (2021) Succinate anaplerosis has an onco-driving potential in prostate cancer cells. Cancers 13:1727.»Bioblast link«
- from the O2k-Network »AT Innsbruck Oroboros« and »FR Bordeaux Rossignol R«
- Sep-06 Tu
How does proficiency testing help achieve quality and reproducibility?
Providing a pre-established set of testing criteria improves and standardizes technical performance.
- »Proficiency test«
- communicated by »Baglivo Eleonora« and »Tindle-Solomon Lisa«
- Sep-07 We
- Sep-08 Th
- Sep-09 Fr
Aug 2022
2022 Week 31
- Aug-01 Mo
154th Oroboros O2k-Coaching Days - Advanced and NextGen-O2k Aug 1-5
O2k-checklist: Get started with an O2k-experiment
The O2k-checklist provides an overview of all essential steps for starting an O2k-experiment.
- » MiPNet20.04_O2k-checklist«
- » communicated by »Cecatto Cristiane« and »Schmitt Sabine«
- Aug-02 Tu
154th Oroboros O2k-Coaching Days - Advanced and NextGen-O2k Aug 1-5
What are the substrate-uncoupler-inhibitor titration reference protocols?
These protocols provide a common baseline for comparison of mitochondrial respiratory control in a large variety of species, tissues and cell types, mt-preparations and laboratories.
- » SUIT reference protocol«- communicated by »Cardoso Luiza HD« and »Tindle-Solomon Lisa«
- Aug-03 We
154th Oroboros O2k-Coaching Days - Advanced and NextGen-O2k Aug 1-5
O2 flux analysis with DatLab 7.4
Use the O2 analysis template:
- Aug-04 Th
154th Oroboros O2k-Coaching Days - Advanced and NextGen-O2k Aug 1-5
Why do we perform multiple H2O2 calibrations in the Amplex® UltraRed assay?
The sensitivity to H2O2 of the fluorometric signal changes during the experiment as a function of: (1) experimental time and accumulating UltroxRed (similar to resorufin), (2) changes of the optical properties due to titrations, and (3) the radical scavenging capacity of the sample. Therefore, H2O2 calibrations are performed before and after sample addition, and after selected titration steps.
- »Amplex UltraRed« and »Komlodi et al BEC 2021.4«
- Aug-05 Fr
154th Oroboros O2k-Coaching Days - Advanced and NextGen-O2k Aug 1-5
Watch these videos to get started with the Q-Module
2022 Week 32
- Aug-08 Mo
- DatLab 7.4 is available to download free of charge for all customers.
- Please note support for earlier versions will no longer be possible.
- -»Download here«
- DatLab 7.4 is available to download free of charge for all customers.
- Aug-09 Tu
Bioenerg Commun 2022.8: Quality Control
- Baglivo E, Cardoso LHD, Cecatto C, Gnaiger E (2022) Statistical analysis of instrumental reproducibility as internal quality control in high-resolution respirometry. https://doi.org/10.26124/bec:2022-0008
- from the O2k-Network »AT Innsbruck Oroboros«
- Aug-10 We
- Aug-11 Th
- Oroboros innovation: the Sample Holder protecting susceptible samples from damage by stirring in the O2k-chamber.
- Oroboros innovation: the Sample Holder protecting susceptible samples from damage by stirring in the O2k-chamber.
- Aug-12 Fr
2022 Week 33
- Aug-15 Mo
BEC tutorial: Did you know that a cell respiring O2 at 100 amol·s-1·x-1 consumes 60 million O2 molecules per second per cell?
- Apply the Avogadro constant NA and SI prefixes; check Formats: INO2 = InO2 · NA
- Apply the Avogadro constant NA and SI prefixes; check Formats: INO2 = InO2 · NA
InO2 = 100 (amol O2)·s-1·(x cell)-1
INO2 = 60.2·106 (x O2)·s-1·(x cell)-1
- Aug-16 Tu
Exploring photosynthesis and dark respiration in the microalgae Chlamydomonas reinhardtii
- Went N, Di Marcello M, Gnaiger E (2021) Oxygen dependence of photosynthesis and light-enhanced dark respiration studied by High-Resolution PhotoRespirometry. MitoFit Prep 2021.5. doi:10.26124/mitofit:2021-0005
- Aug-17 We
- Aug-18 Th
- Aug-19 Fr
- Aug-20 Sa
Oroboros Instruments has been selected as a Euregio Innovation Prize 2022 finalist for the PB-Module of the NextGen-O2k.
The regions of Tyrol – South Tyrol – Trentino will award the prize to innovations in the health and life sciences.
We are looking forward to presenting our innovation in front of the jury on August 20 at 14:00 in Alpbach, AT.
- » Euregio-Innovationspreis«
- EBEC2022 Aix-en-Provence FR Aug 20-25
2022 Week 34
- Aug-22 Mo
- EBEC2022 Aix-en-Provence FR Aug 20-25
- Aug-23 Tu
-» Erich Gnaiger presenting at EBEC2022 Aix-en-Provence FR - Oxygen dependence of photosynthesis and light-enhanced dark respiration studied by high-resolution PhotoRespirometry
- Aug-24 We
A comparison between H2 and N2 gases on mitochondrial respiration and H2O2 production
-» Sabine Schmitt poster presentation at EBEC2022
- Schmitt S, Gnaiger E (2022) Short-term effect of molecular hydrogen on mitochondrial respiration and hydrogen peroxide production in permeabilized HEK 293T cells. EBEC 2022. »Bioblast link«
- Aug-25 Th
Push and pull effect on the Q-junction
-» Luiza HD Cardoso poster presentation at EBEC2022.
- Cardoso LHD, Donnelly C, Komlodi T, Gnaiger E (2022) Characterizing electron transfer through the mitochondrial Q-junction from fatty acid oxidation and TCA cycle on HEK 293T cells: correlation with respiration. EBEC 2022. »Bioblast link«
- Aug-26 Fr
2022 Week 35
- Aug-29 Mo
An article and video about the NextGen-O2k PhotoBiology Module, which was nominated for the Tyrolean Innovation Prize, were recently published (in German).
- » Read and watch here «
- Aug-30 Tu
Keep it running or switch it off – what is best for your O2k?
Switching off the O2k after use increases the lifespan of the OroboPOS and saves energy
- »MiPNet22.11_O2k-FluoRespirometer_manual« and »MiPNet19.03_O2k-cleaning_and_ISS«
- communicated by »Schmitt Sabine« and »Tindle-Solomon Lisa«
- Aug-31 We
Jul 2022
2022 Week 27
- Jul- 04 Mo
A publication from Bioblast 2022: BEC Inaugural Conference
- Heimler SR, Phang HJ, Bergstrom J, Mahapatra G, Dozier S, Gnaiger E, Molina AJA (2021) Platelet bioenergetics are associated with resting metabolic rate and exercise capacity in older adult women. https://doi.org/10.26124/bec:2022-0002
- Jul- 05 Tu
A publication from Bioblast 2022: BEC Inaugural Conference
- Abed Rabbo M, Stiban J (2022) NUBPL: a mitochondrial Complex I deficiency disorder. https://doi.org/10.26124/bec:2022-0003
- Jul- 06 We
A publication from Bioblast 2022: BEC Inaugural Conference
- Åsander Frostner E, Simón Serrano S, Chamkha I, Donnelly E, Elmér E, Hansson MJ (2022) Towards a treatment for mitochondrial disease: current compounds in clinical development. https://doi.org/10.26124/bec:2022-0004
- Jul- 07 Th
Take some time for history - it adds to your stories:
- Jul- 08 Fr
2022 Week 28
- Jul- 11 Mo
A publication from Bioblast 2022: BEC Inaugural Conference
- Heichler C, Nagy M, Wolf P (2022) Evaluation of hepatotoxic effects of acetaminophen on HepG2 cells by parallel real-time monitoring in a multi-sensor analysis platform for automated cell-based assays. https://doi.org/10.26124/bec:2022-0006
- Jul- 12 Tu
BEC tutorial: Mitochondrial membrane potential and Peter Mitchell’s protonmotive force: elements of the science of bioenergetics.
» BEC tutorial-Living Communications pmF, Schroecken, Austria; 2022 - Sep 30 to Oct 2 - preceding the Oroboros O2k-Workshop on high-resolution respirometry.
- Gnaiger E (2020) Mitochondrial pathways and respiratory control. An introduction to OXPHOS analysis. 5th ed. https://doi.org/10.26124/bec:2020-0002
- Jul- 13 We
- "Assuming a publication charge of € 1200 per article, scientists mentioning mitochondria or photosynthesis pay € 100 000 every day in 2021 for ‘selling’ their output to publishers ― over € 36 Mill per year."
- - Gnaiger E (2021) Beyond counting papers – a mission and vision for scientific publication. https://doi.org/10.26124/bec:2021-0005
- Jul- 14 Th
- Jul- 15 Fr
New version 2 of a preprint from Bioblast 2022: BEC Inaugural Conference
- Donnelly C, Schmitt S, Cecatto C, Cardoso LHD, Komlodi T, Place N, Kayser B, Gnaiger E (2022) The ABC of hypoxia – what is the norm. https://doi.org/10.26124/mitofit:2022-0025.v2
2022 Week 29
- Jul- 18 Mo
What is research?
- »Research«
- Jul- 19 Tu
Do you want to find the best SUIT protocol for your research questions?
- Use the SUITbrowser: »SUITbrowser«
- Jul- 20 We
- Jul- 21 Th
Planning to measure proton flux or mitochondrial membrane potential with ion-selective electrodes in the O2k?
Learn how to assemble the reference electrodes:
- »O2k-Videosupport: Assembly of the reference electrode«
- communicated by »Cardoso Luiza« and »Schmitt Sabine«
- Jul- 22 Fr
2022 Week 30
- Jul-25 Mo
Do scientists take responsibility for energy saving? - Or does biomedical research merely find excuses?
- »Energy saving in research« — more details: MitoPedia: Oroboros QM
- Jul-26 Tu
- Jul-27 We
Body mass M and mass m - what is the difference? Consult MitoPedia for a comment on body mass versus body weight.
- »Body mass with a link to mitObesity«
- Jul-28 Th - World Hepatitis Day
Cells expressing hepatitis B protein X showed increased ROUTINE, LEAK and ET capacity compared to control cells.
- Wang B, Li W, Fang H, Zhou H (2018) Hepatitis B virus infection is not associated with fatty liver disease: Evidence from a cohort study and functional analysis. Mol Med Rep 19:320-26. »Bioblast link«
- Jul-29 Fr
Jun 2022
2022 Week 23
- Jun- 06 Mo
Scientific journals apply yesterday's concepts in the various formats of references with bewildering abbreviations of journals, volumes, issues, page numbers. We can do today's job much better using the BEC https-format — in line with DORA.
- Jun- 07 Tu
- Jun- 08 We - World Brain Tumor Day 2021
- »ESCI 2022 Bari IT« Jun 8-10
- Erich Gnaiger presenting at ESCI 2022 Bari IT - Bioenergetic cluster analysis – diagnostic evaluation of mitochondrial respiratory control in human fibroblasts
- Jun- 09 Th
Are you a beginner or need a refresher on using SUIT protocols with DatLab7.4?
- »O2k-Videosupport: How to perform an experiment with a SUIT DL-Protocol« and »Run DL-Protocol/Set O2 limit in DatLab«
- communicated by »Schmitt Sabine«
- Jun- 10 Fr
- »ESCI 2022 Bari IT«
- Eleonora Baglivo presenting at ESCI 2022 Bari IT - Quality control of mitochondrial respiration medium in high-resolution respirometry with living and permeabilized cells - poster selected for oral presentation
2022 Week 24
- Jun- 13 Mo
- Jun- 14 Tu - World Blood Donor Day
- Jun- 15 We
The central role of the Q-junction in mitochondria
The Q-junction is a point of convergence in the electron transfer system. Electrons flow from different dehydrogenases and respiratory Complexes into the Q-junction and then downstream to Complex III.
- »Q-junction«
- communicated by »Schmitt Sabine«
- Jun- 16 Th
- Jun- 17 Fr
The final program of Bioblast 2022 at a glance
2022, Jun 29 - 30 *** 8 sessions *** Poster session *** Exhibition *** MiPArt *** Social activities
- »Bioblast_2022 Program overview«
- Jun- 18 Sa
BEC 2022.1. - The book of abstracts is online
Gnaiger E, Cardoso LHD, Tindle-Solomon L, Cocco P, eds (2022) Bioblast 2022: BEC inaugural conference. https://doi.org/10.26124/bec:2022-0001
- »Bioenerg Commun 2022.1.«
2022 Week 25
- Jun- 20 Mo
BEC 2022.1. - The book of abstracts is online (2022-06-18)
Gnaiger E, Cardoso LHD, Tindle-Solomon L, Cocco P, eds (2022) Bioblast 2022: BEC inaugural conference. https://doi.org/10.26124/bec:2022-0001
- »Bioenerg Commun 2022.1.«
- Jun- 21 Tu
The final program of Bioblast 2022 at a glance
2022, Jun 29 - 30 *** 8 sessions *** Poster session *** Exhibition *** MiPArt *** Social activities
- »Bioblast_2022 Program overview«
- Jun- 22 We
Co-write a BEC editorial
Join the discussion on Jun 30
- » BEC is the future«
- Jun- 23 Th
10+5 min = 600+300 s or 5 min = 300 s
A maximum of 12 or 5 slides - look at abstracts to come prepared
- »Bioblast_2022 Abstracts of oral presentations«
- Jun- 24 Fr
Posters and exhibition
Speakers: stick to the timeline and join the poster sessions and visit the exhibition
- »Bioblast_2022 Abstracts of poster presentations«
2022 Week 26
- Jun- 27 Mo
Posters and exhibition
Speakers: stick to the timeline and join the poster sessions and visit the exhibition
- »Bioblast_2022 Abstracts of poster presentations«
- Jun- 28 Tu
10+5 min = 600+300 s or 5 min = 300 s
A maximum of 12 or 5 slides - look at abstracts to come prepared
- »Bioblast_2022 Abstracts of oral presentations«
- Jun- 29 We
- Bioblast 2022 Jun 29-30
- Jun- 30 Th
- Bioblast 2022 Jun 29-30
- Jul- 01 Fr
- Jul- 02 Sa
May 2022
2022 Week 18
- May- 02 Mo - Lyme Disease Awareness Month
- »FAT4BRAIN Workshop IOC151 Innsbruck AT« May 2-3
- May- 03 Tu
- May- 04 We
"More systematic profiling of mitochondrial bioenergetic states in the presence and absence of lead molecules or kinase drugs could become an asset for anticipating non-desired off-target drug features."
Torres-Quesada Omar, Strich Sophie, Stefan Eduard (2022) Kinase perturbations redirect mitochondrial function. MitoFit Prep 2022.11. https://doi.org/10.26124/mitofit:2022-0011
- from the O2k-Network »AT Innsbruck Oroboros«
- May- 05 Th
- May- 06 Fr
2022 Week 19
- May- 09 Mo
- May- 10 Tu
- May- 11 We
- May- 12 Th - International Awareness Day for Chronic Immunological and Neurological Diseases
- May- 13 Fr
- May- 14 Sa
- 13:15-14:15 (GMT+2): 152nd Oroboros O2k-Workshop: Continuous monitoring of mitochondrial Coenzyme Q redox state integrated in high-resolution respirometry at 10th Conference of the International Coenzyme Q10 Association 2022 Hamburg DE
- 16:30 (GMT+2): Gnaiger Erich presenting at 10th Conference of the International Coenzyme Q10 Association 2022 Hamburg DE - The mitochondrial Q-junction and coenzyme Q pools: Continuous monitoring of pull and push control of respiration and redox state of the Q-mimetic CoQ2
2022 Week 20
- May- 16 Mo
- May- 17 Tu
How do you know which digitonin concentration to use for permeabilization of the cell plasma membrane when performing experiments with the O2k?
SUIT-010 was designed to determine the optimum digitonin concentration for permeabilization of the cell plasma membrane without damaging the mitochondrial outer membrane.
- »Optimum Digitonin concentration and SUIT-010«
- communicated by »Schmitt Sabine« and »Cecatto Cristiane«
- May- 18 We
- May- 19 Th
"Instrumental QC is a cornerstone for experimental reproducibility."
- Baglivo E, Cardoso LHD, Cecatto C, Gnaiger E (2022) Statistical analysis of instrumental reproducibility as internal quality control in high-resolution respirometry. MitoFit Preprints 2022.18. https://doi.org/10.26124/mitofit:2022-0018.v2
- from the O2k-Network »AT Innsbruck Oroboros«
- May- 20 Fr
2022 Week 21
- May- 23 Mo
- May- 24 Tu
Do you know the different ways to adjust oxygen concentration in the Oroboros O2k?
- May- 25 We
Do you load the correct instrumental background correction according to the actual range of experimental O2 concentrations?
Perform and apply the instrumental background test:
- »O2 background correction in DatLab« and »Instrumental oxygen background«
- May- 26 Th
- May- 27 Fr
Apr 2022
2022 Week 14
- Apr- 04 Mo - April is Parkinson's Awareness Month
"Early stage α-synuclein pathology does not influence mitochondrial respiration in the striatum and amygdala [of mice]"
- Burtscher J, Copin JC, Sandi C, Lashuel HA (2020) Pronounced α-synuclein pathology in a seeding-based mouse model is not sufficient to induce mitochondrial respiration deficits in the striatum and amygdala. eNeuro 7:ENEURO.0110-20.2020. »Bioblast link«
- from the O2k-Network »CH Lausanne Place N« and »CH Lausanne Sandi C«
- Apr- 05 Tu
- Apr- 06 We
- Apr- 07 Th - World Health Day
- Apr- 08 Fr
2022 Week 15
- Apr- 11 Mo - World Parkinson´s Disease Day
Reviewing cellular models to decipher the mechanisms of mitochondrial dysfunction in Parkinson's disease
- Krako Jakovljevic N, Ebanks B, Katyal G, Chakrabarti L, Markovic I, Moisoi N (2021) Mitochondrial homeostasis in cellular models of Parkinson’s disease. Bioenerg Commun 2021.2. https://doi.org/10.26124/bec:2021-0002
- from the O2k-Networks »RS Belgrade Lalic NM«, »UK Nottingham Chakrabarti L« and »UK Leicester Moisoi N«
- Apr- 12 Tu
- Apr- 13 We
- Apr- 14 Th
Did you know that you can apply instrumental O2 background test parameters (i.e., intercept and slope) from an existing file in DatLab?
In the DatLab file, you can copy the Instrumental O2 background test parameters directly via the ‘Copy from file’ option in the ‘Slope configuration’ window. For more information, see: - »Copy from file«
- communicated by »Cecatto Cristiane«
- Apr- 15 Fr
2022 Week 16
- Apr- 18 Mo
- Apr- 19 Tu
"The physiological Human Plasma-Like Media alters proliferative behavior, mitochondrial bioenergetic states and kinase drug sensitivity of cancer cells when compared to classic cell culture media."
- Torres-Quesada O, Doerrier C, Strich S, Gnaiger E, Stefan E (2022) Human Plasma-Like Media fine-tune mitochondrial function and alter drug sensitivity in cancer cell lines. MitoFit Preprints 2022.8. https://doi.org/10.26124/mitofit:2022-0008
- from the O2k-Network »AT Innsbruck Oroboros«
- Apr- 20 We
- Apr- 21 Th
- Apr- 22 Fr - Earth Day 2022
2022 Week 17
- Apr- 25 Mo
"Proline catabolism through ProDH generates sufficient CIII and CIV proton pumping, supporting ATP production by F1FO-ATPase even when CI is inhibited"
Pallag G, Nazarian S, Ravasz D, Bui D, Komlódi T, Doerrier C, Gnaiger E, Seyfried TN, Chinopoulos C (2022) Proline oxidation leading to high electron flow through reduction of ubiquinone supports ATP production by F1FO-ATPase in mitochondria with inhibited Complex I. MitoFit Preprints 2022.1.v3. https://doi.org/10.26124/mitofit:2022-0001.v3
- from the O2k-Network »AT Innsbruck Oroboros« and »HU Budapest Chinopoulos C«
- Apr- 26 Tu
- Apr- 27 We
- Apr- 28 Th
- Apr- 29 Fr
Mar 2022
2022 Week 9
- Feb- 28 Mo - Rare disease day
Oroboros Instruments is pleased to collaborate in the CureMILS project
Led by O2k-Network member, Alessandro Prigione, the project aims to employ a novel approach to enable drug discovery for treatment of Mitochondrial DNA (mtDNA)-associated Leigh syndrome (MILS).
- - »CureMILS«
- Mar- 01 Tu - Multiple Sclerosis Awareness Month
- Presenting data from a pilot study on mitochondria bioenergetics and PTSD, Alexander Karabatsiakis will join us at Bioblast 2022.
- -»Bioblast 2022« , »Karabatsiakis Alexander«
- Presenting data from a pilot study on mitochondria bioenergetics and PTSD, Alexander Karabatsiakis will join us at Bioblast 2022.
- Mar- 02 We
- NextGen-O2k key opinion leader Tomas Morosinotto has confirmed his talk on Photosynthetic capacity under oscillating light regimes at Bioblast 2022.
- -»Bioblast 2022« , »Morosinotto Tomas«
- NextGen-O2k key opinion leader Tomas Morosinotto has confirmed his talk on Photosynthetic capacity under oscillating light regimes at Bioblast 2022.
- Mar- 03 Th - World Wildlife Day
- Mar- 04 Fr
- Luboš Sobotka from Charles University, CZ will present The Crabtree effect and clinical nutrition at Bioblast 2022.
- -»Bioblast 2022« , »Sobotka Lubos«
- Luboš Sobotka from Charles University, CZ will present The Crabtree effect and clinical nutrition at Bioblast 2022.
2022 Week 10
- Mar- 07 Mo
- Johnny Stiban from Birzeit University, PS will be presenting Barth Syndrome: A Genetic Ailment with a Lipid Component and Bioenergetic Ramifications at Bioblast 2022.
- -»Bioblast 2022« , »Stiban Johnny«
- Johnny Stiban from Birzeit University, PS will be presenting Barth Syndrome: A Genetic Ailment with a Lipid Component and Bioenergetic Ramifications at Bioblast 2022.
- Mar- 08 Tu - International Women´s Day
- Mar- 09 We
- From the Medical University Innsbruck, AT we will have Günter Weiss presenting on the linkage of iron availability to mitochondrial function.
- -»Bioblast 2022« , »Weiss Guenter«
- From the Medical University Innsbruck, AT we will have Günter Weiss presenting on the linkage of iron availability to mitochondrial function.
- Mar- 10 Th - World Kidney Day
"AT1 receptors and AT2 receptors are expressed in kidney mitochondria and can directly regulate mitochondrial respiration."
- Friederich-Persson M, Persson P (2020) Mitochondrial angiotensin II receptors regulate oxygen consumption in kidney mitochondria from healthy and type 1 diabetic rats. Am J Physiol Renal Physiol 318:F683-88. »Bioblast link«
- from the O2k-Network »SE Uppsala Liss P«
- Sasanka Chakrabarti has confirmed his Bioblast 2022 presentation on rotenone cytotoxicity on SH-SY5Y cells.
- -»Bioblast 2022« , »Chakrabarti Sasanka«
- Sasanka Chakrabarti has confirmed his Bioblast 2022 presentation on rotenone cytotoxicity on SH-SY5Y cells.
- Mar- 11 Fr
- The O2k-Network lab of Stefan Schneeberger at the Medical University Innsbruck, AT will be presenting Pre-transplant mitochondrial respiration as a clinical prognostic marker in liver machine perfusion at Bioblast 2022.
- -»Bioblast 2022« , »AT Innsbruck Schneeberger S«
- The O2k-Network lab of Stefan Schneeberger at the Medical University Innsbruck, AT will be presenting Pre-transplant mitochondrial respiration as a clinical prognostic marker in liver machine perfusion at Bioblast 2022.
2022 Week 11
- Mar- 14 Mo
- TissueModels project partner Markus Keller will present Lipidomics of mitochondrial membranes - methods first at Bioblast 2022.
- -»Bioblast 2022« , »TissueModels«
- TissueModels project partner Markus Keller will present Lipidomics of mitochondrial membranes - methods first at Bioblast 2022.
- Mar- 15 Tu
"MDH2 is a metabolic switch rewiring [electron transfer system] and TCA fuelling"
- Molinié T, Cougouilles E, David C, Cahoreau E, Portais JC, Mourier A (2022) MDH2 produced OAA is a metabolic switch rewiring the fuelling of respiratory chain and TCA cycle. Biochim Biophys Acta Bioenerg 1863:148532. »Bioblast link«
- from the O2k-Network »FR Bordeaux Mourier A«
- Mar- 16 We
Bioenergetics Communications has signed the Declaration on Research Assessment DORA. «
- Mar- 17 Th
- NextGen-O2k key opinion leader Anthony Moore will give a talk on the bioenergetics of alternative oxidases at Bioblast 2022.
- -»Bioblast 2022« , »Moore Anthony L«
- NextGen-O2k key opinion leader Anthony Moore will give a talk on the bioenergetics of alternative oxidases at Bioblast 2022.
- Mar- 18 Fr
Paywall journalism is the opposite of Open Access.
Though often defined from the individual reader's perspective, a paywall can also apply to an institution (such as a library) or the author.
- »Paywall journalism« , »Gnaiger (2021) Editorial Bioenerg Commun«
2022 Week 12
- Mar- 21 Mo - World Down Syndrome Day
"A correlation between the reduced respiratory activity and the morphological alterations in DS-HFF [Down Syndrome human primary lines of foetal fibroblasts] mitochondria indicates that the occurrence of de-structured cristae might partly account for the dysfunctioning oxidative phosphorylation in trisomic samples"
- Piccoli C, Izzo A, Scrima R, Bonfiglio F, Manco R, Negri R, Quarato G, Cela O, Ripoli M, Prisco M, Gentile F, Calì G, Pinton P, Conti A, Nitsch L, Capitanio N (2013) Chronic pro-oxidative state and mitochondrial dysfunctions are more pronounced in fibroblasts from Down syndrome foeti with congenital heart defects. Hum Mol Genet 22:1218-32. »Bioblast link«
- from the O2k-Network »IT Foggia Capitanio N«
- Mar- 22 Tu
- At Bioblast 2022 Leonid A Sazanov will present Why Complex I - Complex II is complex too.
- -»Bioblast 2022« , »Sazanov Leonid A«
- At Bioblast 2022 Leonid A Sazanov will present Why Complex I - Complex II is complex too.
- Mar- 23 We
- Charles Hoppel will contribute to Bioblast 2022 with his talk on diagnostic monitoring of skeletal mitochondrial metabolism.
- -»Bioblast 2022« , »Hoppel Charles L«
- Charles Hoppel will contribute to Bioblast 2022 with his talk on diagnostic monitoring of skeletal mitochondrial metabolism.
- Mar- 24 Th - World Tuberculosis Day
- Mar- 25 Fr
An article about the NextGen-O2k was recently published in six languages on the CORDIS EU website.
- » Read here «
2022 Week 13
- Mar- 28 Mo
- Mar- 29 Tu
- Mar- 30 We
- »Mitochondrial Communications Serial Webinar 4 2022 Virtual« 20:00-21:30 (GMT+8)
- Mar- 31 Th
- Shilpa Iyer has confirmed her contribution Understanding Bioenergetics health index and disease severity in mitochondrial disease fibroblasts to Bioblast 2022.
- -»Bioblast 2022« , »Iyer Shilpa«
- Shilpa Iyer has confirmed her contribution Understanding Bioenergetics health index and disease severity in mitochondrial disease fibroblasts to Bioblast 2022.
- Apr- 01 Fr - Parkinson´s Awareness Month
Feb 2022
2022 Week 5
- Jan- 31 Mo
- Feb- 01 Tu
From preprint to journal publication:
- Vernerova A, Garcia-Souza LF, Soucek O, Kostal M, Rehacek V, Krcmova LK, Gnaiger E, Sobotka O (2021) Mitochondrial respiration of platelets: comparison of isolation methods. Biomedicines 9:1859. doi.org/10.3390/biomedicines9121859
- from the O2k-Network »CZ Hradec Kralove Cervinkova Z« and »AT Innsbruck Oroboros«
- Feb- 02 We
- Feb- 03 Th
- Feb- 04 Fr
Acute sarcoplasmic reticulum calcium leak increases mitochondrial respiration after simulated sprint interval training
- Zanou N, Dridi H, Reiken S, Imamura de Lima T, Donnelly C, De Marchi U, Ferrini M, Vidal J, Sittenfeld L, Feige JN, Garcia-Roves PM, Lopez-Mejia IC, Marks AR, Auwerx J, Kayser B, Place N (2021) Acute RyR1 Ca2+ leak enhances NADH-linked mitochondrial respiratory capacity. Nat Commun 12:7219. »Bioblast link«
- from the O2k-Network »CH Lausanne Place N« and »ES Barcelona Garcia-Roves PM«
- Zanou N, Dridi H, Reiken S, Imamura de Lima T, Donnelly C, De Marchi U, Ferrini M, Vidal J, Sittenfeld L, Feige JN, Garcia-Roves PM, Lopez-Mejia IC, Marks AR, Auwerx J, Kayser B, Place N (2021) Acute RyR1 Ca2+ leak enhances NADH-linked mitochondrial respiratory capacity. Nat Commun 12:7219. »Bioblast link«
2022 Week 6
- Feb- 07 Mo
- Save-the-date: Bioblast 2022: BEC Inaugural Conference - Jun 28 - Jul 1
- -»Bioblast 2022: Announcements«
- Save-the-date: Bioblast 2022: BEC Inaugural Conference - Jun 28 - Jul 1
- Feb- 08 Tu
Now accepting living communications for Bioblast 2022 - BEC Inaugural Issue
-»More details«
- Feb- 09 We
'The scientific literature is exploding in quantity even as it stands still in literary quality.' - Wells WA (2004) Me write pretty one day: how to write a good scientific paper. J Cell Biol 165:757-8. »Bioblast link« Sequential editions provide an opportunity to improve quality while preventing explosions on quantity. - Gnaiger (2021) Editorial Bioenerg Commun
- Feb- 10 Th
Alterations in molecular and cellular pathways contribute to skeletal muscle-related symptoms in Covid-19 - Soares MN, Eggelbusch M, Naddaf E, Gerrits KHL, van der Schaaf M, van den Borst B, Wiersinga WJ, van Vugt M, Weijs PJM, Murray AJ, Wüst RCI (2022) Skeletal muscle alterations in patients with acute Covid-19 and post-acute sequelae of Covid-19. J Cachexia Sarcopenia Muscle. »Bioblast link«
- from the O2k-Network »NL Amsterdam Wuest RC« and »UK Cambridge Murray AJ«
- Feb- 11 Fr - International Day of Women and Girls in Science
© WK Tirol/ Die Fotografen Oroboros is proud to be one of the top 3 nominees for the Tyrolean Innovation Award for the PhotoBiology-Module.
Following the award ceremony organized by the Tyrolean Chamber of Commerce, state council member Anton Mattle, responsible for economy and industry in Tyrol, accepted our invitation to the opening ceremony of Bioblast 2022.
- -»PB-Module« , »Bioblast 2022«
2022 Week 7
- Feb- 14 Mo - Donor Day
- MitoKIN project partners Eduard Stefan and Omar Torres-Quesada will present Profiling of allosteric kinase inhibitors: a new way to unveil metabolic changes by boosting or preventing mitochondrial function at Bioblast 2022.
- -»Bioblast 2022« , »MitoKIN«
- MitoKIN project partners Eduard Stefan and Omar Torres-Quesada will present Profiling of allosteric kinase inhibitors: a new way to unveil metabolic changes by boosting or preventing mitochondrial function at Bioblast 2022.
- Feb- 15 Tu - International Childhood Cancer Day
- Feb- 16 We
- Werner Koopman has confirmed his presentation at Bioblast 2022 on mitochondrial targeting using the TPP moiety.
- -»Bioblast 2022« , »Koopman Werner JH«
- Werner Koopman has confirmed his presentation at Bioblast 2022 on mitochondrial targeting using the TPP moiety.
- Feb- 17 Th
Read more about the Tyrolean Innovation Award for which we were a top nominee.
- -»Tiroler Wirtshaft article (German)«
- Feb- 18 Fr
2022 Week 8
- Feb- 21 Mo
- The O2k-Network lab of Laszlo Tretter at Semmelweis University in Budapest, HU will be presenting The protonmotive force - not merely membrane potential at Bioblast 2022.
- -»Bioblast 2022« , »HU Budapest Tretter L«
- The O2k-Network lab of Laszlo Tretter at Semmelweis University in Budapest, HU will be presenting The protonmotive force - not merely membrane potential at Bioblast 2022.
- Feb- 22 Tu
- Feb- 23 We
- ALAS project partner Thomas Roach will present Oxidative stress in photosynthesis at Bioblast 2022.
- -»Bioblast 2022« , »ALAS«
- ALAS project partner Thomas Roach will present Oxidative stress in photosynthesis at Bioblast 2022.
- Feb- 24 Th
- Industry partner Incyton will be at Bioblast 2022 with a talk on Long-term monitoring of respiration and morphology of cultured cells.
- -»Bioblast 2022« , »Incyton«
- Industry partner Incyton will be at Bioblast 2022 with a talk on Long-term monitoring of respiration and morphology of cultured cells.
- Feb- 25 Fr
Jan 2022
2022 Week 1
- Jan- 03 Mo
- Jan- 04 Tu
Do you know which graph layout to choose in DatLab?
Different layouts are required depending on which instrumental quality control or measurement with biological sample is performed. Learn more about Standard layouts provided in DatLab:
- »Layout for DatLab graphs«
- communicated by »Schmitt Sabine« and »Komlodi Timea«
- Jan- 05 We
- Jan- 06 Th
- Jan- 07 Fr
Oxia: O2 regime controller for HyperOxia to HypOxia in the O2k
- » Learn more here «
2022 Week 2
- Jan- 10 Mo
Oroboros Instruments supports Bioenergetics Communications.
- » We have signed the Declaration on Research Assessment DORA. «
- Jan- 11 Tu
- Jan- 12 We
- Jan- 13 Th
- Jan- 14 Fr
2022 Week 3
- Jan- 17 Mo
'Assuming a publication charge of € 1200 per article, scientists mentioning mitochondria or photosynthesis pay € 100 000 every day in 2021 for ‘selling’ their output to publishers ― over € 36 Mill per year. ' - Gnaiger (2021) Editorial Bioenerg Commun
- Jan- 18 Tu
The process of Lewy body formation in Parkinson's Disease induces mitochondrial deficits
- Mahul-Mellier AL, Burtscher J, Maharjan N, Weerens L, Croisier M, Kuttler F, Leleu M, Knott GW, Lashuel HA (2020) The process of Lewy body formation, rather than simply α-synuclein fibrillization, is one of the major drivers of neurodegeneration. Proc Natl Acad Sci U S A 117:4971-82. Mahul-Mellier 2020 Proc Natl Acad Sci U S A
- from the O2k-Network »CH Lausanne Place N«
- Jan- 19 We
Elsevier bought Pergamon Press in 1991 for £440m (£919m today) from Robert Maxwell. R Maxwell may be known in relation to financial scandals and to his daughter Ghislaine Maxwell who was convicted on 2021-12-29 linked to several federal crimes including her involvement in a sex-trafficking ring with Jeffrey Epstein, to who's former friends belonged British Prince Andrew, former Prime Minister Tony Blair, or ex-US-presidents Bill Clinton and Donald Trump. Due to paywall journals, Open Access in science remains an unfulfilled dream. - Gnaiger (2021) Editorial BEC Living Communication (2022-01-04)
- Jan- 20 Th
The Q-Module of the NextGen O2k enables electrochemical monitoring of the redox state of the ETS-reactive coenzyme Q pool.
- » Learn more here «
- Jan- 21 Fr
'The burden of responsibilities for an urgent change of the academic publishing ecosystem and scientific communication culture must be shared between the shoulders of individual scientists, the backbone of scientific institutions, and the neurology of governmental regulations and funding agencies.' - Gnaiger (2021) Editorial Bioenerg Commun
2022 Week 4
- Jan- 24 Mo
Oroboros Instruments presents the NextGen-O2k Q-Module at the Q10 Conference: - »10th Conference of the International Coenzyme Q10 Association 2022 Hamburg DE« May 12-15
- - Poster deadline has been extended to the 6th of February
- Jan- 25 Tu
From preprint to journal publication:
- Fischer C, Volani C, Komlódi T, Seifert M, Demetz E, Valente de Souza L, Auer K, Petzer V, von Raffay L, Moser P, Gnaiger E, Weiss G (2021) Dietary iron overload and Hfe-/- related hemochromatosis alter hepatic mitochondrial function. Antioxidants 10:1818. doi.org/10.3390/antiox10111818
- from the O2k-Network »AT Innsbruck Oroboros«
- Jan- 26 We
Measure photosynthesis and light enhanced dark respiration with the PB-Module of the NextGen O2k.
- » Learn more here «
- Jan- 27 Th
- Jan- 28 Fr
Stay alert
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