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: http://wiki.oroboros.at/index.php/OROBOROS_home
: http://wiki.oroboros.at/index.php/About_Oroboros




[[Image:Logo_OROBOROS_INSTRUMENTS.jpg|left|150px|link=http://wiki.oroboros.at/index.php/OROBOROS_INSTRUMENTS |OROBOROS]]
=== Oroboros navigation ===
[[OROBOROS INSTRUMENTS]] distributes the world-wide leading O2k-technology of high-resolution respirometry - '''O2k and HRR'''. The [[OROBOROS Company]] is fully scientifically oriented, with emphasis on continuous innovation. The extension of the [[Oxygraph-2k]] (O2k) to the [[O2k-Fluorometer]] has set a new standard for O2k-MultiSensor approaches (see [[OROBOROS O2k-Catalogue]]). The O2k is established internationally, with [[O2k-Publications: Topics |Β»{{#ask:[[Category:Publications]][[Instrument andΒ  method::Oxygraph-2k]] |format=count}} O2k-Publications]] in the scientific literature. OROBOROS has organized more than 100 international [[OROBOROS_Events#Next_O2k-Workshops |O2k-Workshops]]. The [[O2k-Network]] includes more than 350 Reference Laboratories in 45 countries.
[[File:O2k-Concept.jpg|250px|right|thumb|link=http://wiki.oroboros.at/index.php/Oroboros_O2k|O2k]]
<big>'''Β» [[Oroboros O2k]]</big>: the modular system for [[high-resolution respirometry|High-Resolution FluoRespirometry]]''', and mitochondrial physiology




=== The [[O2k]] for high-resolution respirometry ===
[[Image:O2k-Info.png|left|60px|link=http://wiki.oroboros.at/index.php/Oroboros_O2k-Catalogue|O2k-Catalogue]]
[[Image:O2k-Fluorometer.JPG|left|150px|link=http://wiki.oroboros.at/index.php/Oxygraph-2k |O2k]]
==== [[Oroboros O2k-Catalogue]] - a guided tour to the O2k ====
:: O2k is the acronym for the OROBOROS '''[[Oxygraph-2k]]''' and '''[[O2k-Fluorometer]]''' - the modular system for high-resolution respirometry and mitochondrial physiology. The O2k provides a unique high-resolution approach for the monitoring of cellular and mitochondrial respiratory function: [[high-resolution respirometry |high-resolution respirometry (HRR)]]. Considering mitochondria as the powerhouses of the cell, HRR introduced the concept of [[cell ergometry]]. Are your cells [[MitoFit]]?
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HRR is applied [[O2k-Network |world-wide]] in areas ranging from fundamental bioenergetics to the analysis of mitochondrial and metabolic diseases, advancing the rapidly growing field of preventive mitochondrial medicine. Mitochondrial fitness needs to be monitored in a variety of age-related health risks, including cardiovascular and degenerative diseases, such as type 2 diabetes, neurodegenerative diseases (Alzheimer’s, Parkinson’s, Huntington’s), and several types of cancer.
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==== [[OROBOROS MitoFit Laboratory]] ====
[[File:OROBOROS MitoFit-Lab.jpg|left|240px|link=http://wiki.oroboros.at/index.php/OROBOROS_INSTRUMENTS |OROBOROS]]
HRR by the OROBOROS O2k is based on a radically different systems approach to polarographic measurement of oxygen dynamics. HRR rests on several tightly connected instrumental features and concepts integrated by the DatLab software, providing real-time display of oxygen concentration and respiration ([[oxygen flux]]). The mechanics, critical selection of materials, and state-of-the-art electronics provide the basis of signal stability of an optimized [[polarographic oxygen sensor]], in an electronically controlled thermal environment with high temperature stability. Calibrations and instrumental controls follow standard operating procedures, with highly automatic real-time analysis by the DatLab software. Scientific support is complementary to the approach of HRR.
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==== [[Cell ergometry]] ====
[[File:EPL-free and excess.jpg|left|240px|link=Gnaiger 2014 MitoPathways |Gnaiger 2014 MitoPathways]]
::* '''Β»''' A concept complete with elaborated protocols, to get started and gain competence in the expanding field of bioenergetics: Β» [[Gnaiger 2014 MitoPathways |Blue Book 2014]] - Β» [[O2k-Protocols]].
::* '''Β»''' Explore cell respiration and key mitochondrial functions''': [[High-resolution respirometry |Β» HRR]] and the [http://www.oroboros.at/?Oxygraph Β» O2k].
::* '''Β»''' Introductory courses and advanced training: Β» [[OROBOROS_Events]].
::'''Β»'''Β  [http://www.oroboros.at/?Purchase WorldWide distribution].
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=== The O2k concept ===
[[Image:Oxygraph-2k-Concept.jpg|250px|right|thumb|link=http://wiki.oroboros.at/index.php/Oxygraph-2k|Oxygraph-2k]]
<big>'''Β» [[Oxygraph-2k | OROBOROS Oxygraph-2k]]</big>: the modular system for [[high-resolution respirometry]]''' and mitochondrial physiology
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[[Image:O2k-Info.png|left|60px|link=http://wiki.oroboros.at/index.php/OROBOROS_O2k-Catalogue|O2k-Catalogue]]
==== [[OROBOROS O2k-Catalogue]] - a guided tour to the O2k ====
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:: Multiple O2k-units are offered as a β€˜[[Power-O2k]] System’ for HRR combined with high-throughput - at high output.
:: Multiple O2k-units are offered as a β€˜[[Power-O2k]] System’ for HRR combined with high-throughput - at high output.


[[Image:O2k-Support.jpg|left|60px||link=http://wiki.oroboros.at/index.php/O2k-technical_support_and_open_innovation |OROBOROS support]]
[[Image:O2k-Support.jpg|left|60px||link=http://wiki.oroboros.at/index.php/O2k-Open_Support |Oroboros support]]
==== [[O2k-technical support and open innovation]] ====
==== [[O2k-Open Support]] ====
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[[Image:O2k-Manual.jpg|left|60px|link=O2k-Manual|O2k-Manual]]
[[Image:O2k-Manual.jpg|left|60px|link=O2k-Manual|O2k-Manual]]
[[Image:OROBOROS-Concept.jpg|right|500px|OROBOROS O2k-Info]]
[[Image:Oroboros Ecosystem.jpg|right|500px|Oroboros Ecosystem]]
==== [[O2k-Manual]] ====
==== [[O2k-Manual]] ====
:: Instructions to application and service of the [[O2k-Core]], [[TIP2k]] and [[O2k-Catalogue:_O2k-MultiSensor|O2k-MultiSensor Modules]].
:: Instructions to application and service of the [[O2k-Core|Oroboros O2k]], [[TIP2k]] and [[O2k-Catalogue:_O2k-MultiSensor|O2k-MultiSensor Modules]].
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[[Image:O2k-Protocols.jpg|left|60px|link=http://wiki.oroboros.at/index.php/O2k-Protocols |O2k-Protocols]]
[[Image:O2k-Protocols.jpg|left|60px|link=http://wiki.oroboros.at/index.php/O2k-Protocols |O2k-Protocols]]
==== [[O2k-Protocols]] ====
==== [[O2k-Procedures]] ====
:: O2k-Protocols are complementary to the O2k-Manual and O2k-Publications. Users are encouraged to get involved, contribute and share their expertise.
:: O2k-Procedures are complementary to the O2k-Manual and O2k-Publications.




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}} O2k-Publications]] are part of the category '''[[Special:BrowseData/Publications|Publications]]''', providing a portal for sharing, disseminating and commenting relevant literature in mitochondrial physiology. Bioblast allows the β€œevolution” of a publication with space for open discussions and extensions of an otherwise static β€˜paper’. This applies specifically to ''Methods and Materials'', ''Discussion'', and ''References'' sections, which may be limited by space in original publications. Β 
}} O2k-Publications]] are part of the category '''[[Special:BrowseData/Publications|Publications]]''', providing a portal for sharing, disseminating and commenting relevant literature in mitochondrial physiology. Bioblast allows the β€œevolution” of a publication with space for open discussions and extensions of an otherwise static β€˜paper’. This applies specifically to ''Methods and Materials'', ''Discussion'', and ''References'' sections, which may be limited by space in original publications. Β 


[[Image:O2k-Workshops.jpg|left|60px|link=http://wiki.oroboros.at/index.php/OROBOROS-Events |O2k-Workshops and Events]]
[[Image:O2k-Workshops.jpg|left|60px|link=http://wiki.oroboros.at/index.php/Oroboros Events |O2k-Workshops and Events]]
==== [[OROBOROS-Events]]: O2k-Workshops and Events ====
==== [[Oroboros Events]]: O2k-Workshops and Events ====
:: Join us in the fast lane to high-resolution respirometry. While the OROBOROS O2k provides the instrumental basis for HRR, successful operation at high accuracy up to the limit of detection depends on a professional application by the technician, scientist or student. Participation in our hands-on introductory [[OROBOROS O2k-Workshops]] is recommended to save time and gain from the experience obtained over many years of application in various [[The world as a laboratory |settings]].
:: Join us in the fast lane to high-resolution respirometry. While the Oroboros O2k provides the instrumental basis for HRR, successful operation at high accuracy up to the limit of detection depends on a professional application by the technician, scientist or student. Participation in our hands-on introductory [[Oroboros Events#Next O2k-Workshops |Oroboros O2k-Workshops]] is recommended to save time and gain from the experience obtained over many years of application in various [[The World as a Laboratory |settings]].


[[Image:O2k-Network.png|left|60px|link=http://wiki.oroboros.at/index.php/O2k-Network |O2k-Network]]
[[Image:O2k-Network.png|left|60px|link=http://wiki.oroboros.at/index.php/O2k-Network |O2k-Network]]
==== [[O2k-Network]] ====
==== [[O2k-Network]] ====
:: [[O2k-Network]] Labs from all over the world join to form the unique OROBOROS O2k-Network for high-resolution respirometry.
:: [[O2k-Network]] Labs from all over the world join to form the unique Oroboros O2k-Network for high-resolution respirometry.


[[Image:The world as a laboratory.jpg|left|60px|link=http://wiki.oroboros.at/index.php/The_world_as_a_laboratory |The world as a laboratory]]
[[Image:The world as a laboratory.jpg|left|60px|link=https://wiki.oroboros.at/index.php/The_World_as_a_Laboratory |The World as a Laboratory]]
==== [[The world as a laboratory]] - science and adventure ====
==== [[The World as a Laboratory]] - science and adventure ====
:: Science and adventure brings the OROBOROS-Team and the O2k to many and sometimes extreme parts of the world in international collaborations - [[The world as a laboratory]].
:: Science and adventure brings the Oroboros-Team and the O2k to many and sometimes extreme parts of the world in international collaborations - [[The World as a Laboratory]].


[[File:MiPNet.jpg|left|60px|link=http://wiki.oroboros.at/index.php/Mitochondr_Physiol_Network |Mitochondr Physiol Network]]
[[File:MiPNet.jpg|left|60px|link=http://wiki.oroboros.at/index.php/Mitochondr_Physiol_Network |Mitochondr Physiol Network]]
==== [[Mitochondr Physiol Network]] ====
==== [[Mitochondr Physiol Network]] ====
:: [[Mitochondr Physiol Network |Mitochondrial Physiology Network]] - the OROBOROS on-line journal with Open Access in the spirit of [[Gentle Science]].
:: [[Mitochondr Physiol Network |Mitochondrial Physiology Network]] - the Oroboros on-line journal with Open Access in the spirit of [[Gentle Science]].


[[Image:O2k-Feedback.jpg|left|60px|link=http://wiki.oroboros.at/index.php/O2k-Feedback |O2k-Feedback]]
[[Image:O2k-Feedback.jpg|left|60px|link=http://wiki.oroboros.at/index.php/O2k-Feedback |O2k-Feedback]]
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[[Image:OROBOROS-Company.jpg|left|60px|link=http://wiki.oroboros.at/index.php/OROBOROS_Company |OROBOROS Company]]
[[Image:OROBOROS-Company.jpg|left|60px|link=http://wiki.oroboros.at/index.php/Oroboros_contact|Oroboros contact]]
==== [[OROBOROS Company]] - OROBOROS-Team ====
==== [[Oroboros contact]] - Oroboros-team ====
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[[Image:OROBOROS-Contact.jpg|left|60px|link=http://wiki.oroboros.at/index.php/http://wiki.oroboros.at/index.php/OROBOROS_Contact |OROBOROS Contact]]
==== [[Oroboros Ecosystem history]] ====
==== [[OROBOROS Contact]] ====
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Latest revision as of 16:53, 1 December 2019

http://wiki.oroboros.at/index.php/About_Oroboros


Oroboros navigation

O2k

Β» Oroboros O2k: the modular system for High-Resolution FluoRespirometry, and mitochondrial physiology


O2k-Catalogue

Oroboros O2k-Catalogue - a guided tour to the O2k




Power-O2k

From the O2k to the Power-O2k

Multiple O2k-units are offered as a β€˜Power-O2k System’ for HRR combined with high-throughput - at high output.
Oroboros support

O2k-Open Support



O2k-Manual
Oroboros Ecosystem

O2k-Manual

Instructions to application and service of the Oroboros O2k, TIP2k and O2k-MultiSensor Modules.



O2k-Protocols

O2k-Procedures

O2k-Procedures are complementary to the O2k-Manual and O2k-Publications.


O2k-Publications in the MiPMap

O2k-Publications

Β»4710 O2k-Publications are part of the category Publications, providing a portal for sharing, disseminating and commenting relevant literature in mitochondrial physiology. Bioblast allows the β€œevolution” of a publication with space for open discussions and extensions of an otherwise static β€˜paper’. This applies specifically to Methods and Materials, Discussion, and References sections, which may be limited by space in original publications.
O2k-Workshops and Events

Oroboros Events: O2k-Workshops and Events

Join us in the fast lane to high-resolution respirometry. While the Oroboros O2k provides the instrumental basis for HRR, successful operation at high accuracy up to the limit of detection depends on a professional application by the technician, scientist or student. Participation in our hands-on introductory Oroboros O2k-Workshops is recommended to save time and gain from the experience obtained over many years of application in various settings.
O2k-Network

O2k-Network

O2k-Network Labs from all over the world join to form the unique Oroboros O2k-Network for high-resolution respirometry.
The World as a Laboratory

The World as a Laboratory - science and adventure

Science and adventure brings the Oroboros-Team and the O2k to many and sometimes extreme parts of the world in international collaborations - The World as a Laboratory.
Mitochondr Physiol Network

Mitochondr Physiol Network

Mitochondrial Physiology Network - the Oroboros on-line journal with Open Access in the spirit of Gentle Science.
O2k-Feedback

O2k-Feedback


Oroboros contact

Oroboros contact - Oroboros-team


Oroboros Ecosystem history

Company of Scientists

http://www.company-of-scientists.com
Company of Scientists

Company of Scientists

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