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...observations provide insights into eukaryotic NADP(+) biosynthesis, which has pivotal roles in cells and organelles.

...tained at -0.600 V vs Ag/AgCl. The magnitude of the oxidation peak current has been found to be related to the concentration of the coenzyme over the rang

...fully revealed. Owing to its safety and potential efficacy, H₂ has a promising potential for clinical use against many diseases. This review w

...bstrate for Complex II which accumulates during mitochondrial dysfunction, has been shown to have widespread effects as a signaling molecule. Here, we rev

{{Abstract ...mitochondria in a tissue. In patients with peripheral arterial disease it has been shown that the function and the amount of mitochondria depends on the

...erformed. Such as sample has to be stable for a certain amount of time and has to deliver the same results over and over ...nts have been done in certain intervals. The process of shipping the cells has also been mimicked by storing cells in a -20°C freezer for the period of o

...ondria and low oxidative capacity. The heat-producing brown adipose tissue has a high density of mitochondria and high oxidative capacity. Mitochondrial f

...nstruction of PI curves of unicellular organisms based on oxygen evolution has been difficult and time consuming due to the lack of sensitive instruments. :::: Supported by project [[NextGen-O2k]] which has received funding from the European Union’s Horizon 2020 research and inno

{{Abstract ...at an impaired mitochondrial function in one tissue (e.g. skeletal muscle) has strong metabolic consequences for the whole organism.

...and international trade, ''Where Corals Lie'' reveals how the threatening has become threatened; and of the danger this poses to humans. Exceptionally em

|abstract=.. From the start of my scientific career the galvanic cell, the first form ...appreciable elaboration since its acceptance, surely a clear sign that it has so far satisfied scientific needs. ..

...reviewed, a clear understanding of the regulation of cellular respiration has not yet been achieved. In particular, the role of tissue pO2 as a factor re cellular and intercellular messengers has evolved in the last few years and is

...t times of infection. Taking together, these results demonstrated that DHA has a potential anti-inflammatory and neuroprotective effect against ZIKV infec

{{Abstract ...lth consequences associated with excess weight, to the extent that obesity has recently been classified as a disease. Calorie restriction can induce weigh

...ax</sub>) with respect to ubiquinol-10 have been determined. The PL system has also been employed in dose-response assays with novel AOX inhibitors. Such

...tract=The interplay between platelets and tumors has long been studied. It has been widely accepted that platelets could promote tumor metastasis. However

...ts impair the specificities of cancer drugs. Blockade of kinase activities has been shown to converge on the energetic organelle, the mitochondria. In thi

...as important causes of disease. In addition, the study of these disorders has led to a greater understanding of the molecular mechanism of beta-oxidation

...e material into the body's own tissue. Unfortunately, however, this method has not yet arrived in practice. Therefore, we have made our own efforts to est

{{Abstract ...using reverse transcriptase polymerase chain reaction (RT-PCR) experiments has demonstrated that these genes are transcribed in many organisms [3]. Our fo

...nucleotide pool from tissue is dependent on the assay method. NADH ED-FRAP has been shown to be effective in measuring dehydrogenase activity in several e

...m of tissue cannot be obtained. Often, 0.5 grams must suffice. This method has been used successfully for the isolation of heart mitochondria from several

...electron transfer chain impairments, mitochondrial apoptosis and mitophagy has been outlined. Meanwhile, considerable efforts have been made towards under

{{Abstract ...efficiency through uncoupling. Mitochondrial heat generation in bumblebees has been largely discounted as they appear to lack uncoupling proteins, and if

...stress. This study aimed to demonstrate whether exercise before pregnancy has a protective effect on prenatal stress-induced impairment of memory, neurog

...ny such special properties. We review evidence here showing that trehalose has a remarkably high glass-transition temperature (Tg). It is not anomalous in

...t includes administering to the subject a pharmaceutical composition which has a therapeutically effective amount of an antimicrobial peptide containing a

...circulating to distant tissues. It is noteworthy that increasing evidence has demonstrated that mitokines are capable of reducing the metabolic-related H

|abstract=Worldwide, 1 in 3 women and 1 in 5 men over age 50 will experience fracture decline of bone with aging has been well studied, we were the first to find a

|abstract= TRACT General assembly meeting, Belfast, United Kingdom, 2018 This project has received funding from the European Union's Horizon 2020 research and innova

...ng, while itaconate (from another Krebs cycle intermediate, cis-aconitate) has an anti-inflammatory role.

...egulate autophagy and mitochondrial quality control. Conversely, autophagy has been shown to preserve NAD levels by modulating cellular stress. In this re

...ort chain into higher order assemblies, termed respiratory supercomplexes, has been established. Moreover, cardiolipin is involved in different stages of

...majority of the literature is not supporting this hypothesis. Recently it has been suggested that the production of reactive oxygen species play an essen

{{Abstract |abstract=[[Image:MITOEAGLE-logo.jpg|left|100px|link=http://www.mitoglobal.org/index.

|abstract= 32nd APS Annual Convention, Chicago, USA, 2020 :::: APS has regrettably determined it has no alternative but to cancel our in-person 32nd APS Annual Convention in Ch

...system in the cristae membrane under a mainly electrical p.m.f., Baum [6] has asked how the very small number of free protons in the inner aqueous phase

...ations in mitochondrial DNA on the rate of mitochondrial protein synthesis has revealed the existence of a 'translational threshold effect'. In this revie

|abstract=The subunit structure of oligomycin sensitive ATPase has been determined. In addition to the components of F1, and the so-called oli

...ace-water oxygenation. The discovery and cultivation of the Asgard archaea has reinforced metabolic evidence that eukaryogenesis was initially mediated by

{{Abstract ...ts impair the specificities of cancer drugs. Blockade of kinase activities has been shown to converge on the energetic organelle, the mitochondria. In thi

...tions have directed researchers towards utilising stem cells. Mitochondria has a major involvement in the pathophysiology of stroke and a number of other

...ure, the active site and quinone-binding site. Characterisation of the AOX has advanced considerably over recent years with information emerging about the

...cted debate. By contrast, recent application of molecular biological tools has brought major enlightenment at an exponential pace. Here we review some key

...lymphoid malignancies. An initial insufficient response to glucocorticoids has been shown to be an important prognostic marker for a bad outcome. Prior work has shown a downregulation of the mitochondrial glutamate/H+-symporter (SLC25A2

...rd party assessment and caution needed to prevent post-assessment pitfalls has been dealt with.

|title=Bhalla N (2016) Has the time come for preprints in biology? Mol Biol Cell 27:1185-7. |abstract=Preprints, non-peer-reviewed drafts of manuscripts available on the Interne

...nce in the study of cellular metabolism, particularly in the cancer field, has highlighted the fact that mitochondria are also critical biosynthetic and s

|abstract=[[Gnaiger 2022 Abstract Bioblast-PB]]: The bioenergetic crosstalk between mitochondria and chloropl |?Has title=Reference

...the tetrameric interfacial exo site resulted in dimeric mutants. ATP thus has dual functional roles in the mitochondrial malic enzyme.