Shabalina Irina G

News and Events

Working Groups

Short-Term Scientific Missions

Management Committee

Members

COST Action CA15203 (2016-2021): MitoEAGLE
Evolution-Age-Gender-Lifestyle-Environment: mitochondrial fitness mapping

Shabalina Irina G

MitoPedia topics: EAGLE

COST: Member COST WG1: WG1

COST WG3: WG3

Name	Shabalina Irina G., Dr.
Institution	The Wenner-Gren Institute, Stockholm University, SE
Address	The Arrhenius Laboratories F3, SE-10691
City	Stockholm
State/Province
Country	Sweden
Email
Weblink
O2k-Network Lab	SE Stockholm Nedergaard J

Labels: Field of research: Basic Topics: uncoupling proteins, mitochondria, brown and white adipose tissue, mtDNA mutation, mitochondrial ROS production

Publications

	Published	Reference
Shabalina 2024 Biochim Biophys Acta Bioenerg	2024	Shabalina IG, Jiménez B, Sousa-Filho CPB, Cannon B, Nedergaard J (2024) In isolated brown adipose tissue mitochondria UCP1 is not essential for nor involved in the uncoupling effects of the classical uncouplers FCCP and DNP. Biochim Biophys Acta Bioenerg [Epub ahead of print]. https://doi.org/10.1016/j.bbabio.2024.149516
Gao 2022 Biochim Biophys Acta Bioenerg	2022	Gao Y, Shabalina IG, Braz GRF, Cannon B, Yang G, Nedergaard J (2022) Establishing the potency of N-acyl amino acids versus conventional fatty acids as thermogenic uncouplers in cells and mitochondria from different tissues.
Gomez 2022 Nutrients	2022	Gómez Rodríguez A, Talamonti E, Naudi A, Kalinovich AV, Pauter AM, Barja G, Bengtsson T, Jacobsson A, Pamplona R, Shabalina IG (2022) Elovl2-ablation leads to mitochondrial membrane fatty acid remodeling and reduced efficiency in mouse liver mitochondria. https://doi.org/10.3390/nu14030559
BEC 2020.1 doi10.26124bec2020-0001.v1	2020	Gnaiger E et al ― MitoEAGLE Task Group (2020) Mitochondrial physiology. Bioenerg Commun 2020.1. https://doi.org/10.26124/bec:2020-0001.v1
Schilperoort 2018 EMBO Mol Med	2018	Schilperoort M, van Dam AD, Hoeke G, Shabalina IG, Okolo A, Hanyaloglu AC, Dib LH, Mol IM, Caengprasath N, Chan YW, Damak S, Miller AR, Coskun T, Shimpukade B, Ulven T, Kooijman S, Rensen PC, Christian M (2018) The GPR120 agonist TUG-891 promotes metabolic health by stimulating mitochondrial respiration in brown fat. EMBO Mol Med 10:e8047.
Nabben 2011 Biochim Biophys Acta	2011	Nabben M, Shabalina IG, Moonen-Kornips E, van Beurden D, Cannon B, Schrauwen P, Nedergaard J, Hoeks J (2011) Uncoupled respiration, ROS production, acute lipotoxicity and oxidative damage in isolated skeletal muscle mitochondria from UCP3-ablated mice. Biochim Biophys Acta 1807:1095-105.
Fernstroem 2007 J Appl Physiol (1985)	2007	Fernström M, Bakkman L, Tonkonogi M, Shabalina IG, Rozhdestvenskaya Z, Mattsson CM, Enqvist JK, Ekblom B, Sahlin K (2007) Reduced efficiency, but increased fat oxidation, in mitochondria from human skeletal muscle after 24-h ultraendurance exercise. J Appl Physiol 102:1844–9.

Abstracts

	Published	Reference
Shabalina 2018 MiP2018	2018	Elovl2-ablation leads to mitochondrial phospholipid remodeling and reduced oxidative phosphorylation capacity in mouse liver mitochondria.
Shabalina 2017 MiP2017	2017	In UCP1-ablated mice, prolonged cold exposure promotes mitochondrial dysfunction, apoptosis and inflammation in brown adipose tissue, and accumulation of visceral obesogenic fat.
Shabalina 2017 Abstract MITOEAGLE Barcelona	2017	Control of UCP1 activity in brown fat mitochondria.
Nedergaard 2017 MiP2017	2017	Creatine effect in mitochondria from different tissues.
Shabalina 2015 Abstract MiP2015	2015	The metabolically inert environmental pollutants perfluorinated fatty acids directly activate uncoupling protein 1 in brown-fat mitochondria.
Kalinovich 2015 Abstract MiP2015	2015	UCP3-related changes in brown and brite/beige adipose tissue in cold-acclimated mice.
Shabalina 2013 Abstract IOC79	2013	Shabalina IG (2013) Enhanced Complex I but low Complex II substrate-derived ROS production rates in mice, prematurely aging due to enhanced mitochondrial DNA mutation rate. Mitochondr Physiol Network 18.07
Shabalina 2013 Abstract MiP2013	2013	Shabalina IG, Petrovic N, Kalinovich AV, Cannon B, Nedergaard J (2013) Comparative study of brown and white adipose tissue mitochondria in mice upon cold acclimation. Mitochondr Physiol Network 18.08.

Participated at