Difference between revisions of "MitoEAGLE data: muscle"
From Bioblast
| Line 13: | Line 13: | ||
== WG2 Participants == | == WG2 Participants == | ||
{{#ask:[[MitoPedia topic::EAGLE]] [[In country::+]] [[Has COST WG2::+]] | |||
| mainlabel=- | | mainlabel=- | ||
|?In country=Country | |?In country=Country | ||
Revision as of 14:59, 27 April 2016
 |
News and Events |  |
 |
Working Groups | Short-Term Scientific Missions | Management Committee | Members |  |
COST Action CA15203 (2016-2021): MitoEAGLE
Evolution-Age-Gender-Lifestyle-Environment: mitochondrial fitness mapping
MitoEAGLE data: muscle
WG2
- MITOEAGLE data repository in muscle and other tissues
WG2 Description
- During the past 10 years, a dramatically increasing number of studies report respirometric data on human muscle tissue (e.g. Christiansen 2015 Am J Physiol). Muscle mitochondrial function is particularly studied in genetically engineered mouse models of human diseases (e.g. Jelenik 2014 Diabetes). However, despite the many published data, lack of consistency often precludes quantitative comparison among data sets with permeabilized or homogenized muscle fibres or isolated mitochondria, normalized to either tissue wet weight, dry weight, protein content, citrate synthase activity or other mitochondrial markers. In the absence of validated conversion factors, these data remain largely unconnected and can only be qualitatively linked.
- The aim of WG2 will be to provide access to complete data sets for post-study statistical analysis and use harmonization tools (WG1) for standardized documentation, to initiate a data repository on muscle tissue from humans and model organisms in health and disease. Data sets shall be obtained from already published and new studies, prompting participating labs to report experimental details beyond those already published as far as possible (using tools such as PubMed Commons). As a result, specific protocols will be summarized for handling muscle tissue. Depending on specific interests, WG2 may decide to extend their focus to other tissue types.
WG2 Participants
| Country | City | Contact |
|---|---|---|
| Australia | Melbourne | Bishop David J |
| Austria | Innsbruck | Gnaiger Erich |
| Austria | Salzburg | Mayr JA |
| Austria | Innsbruck | Doerrier Carolina |
| Austria | Innsbruck | Laner Verena |
| Belgium | Liege | Votion Dominique-Marie |
| Belgium | Leuven | Bird Matthew |
| Brazil | São Paulo | Ferreira Julio Cesar B |
| Brazil | Jaboticabal, SP | Garcia Geovana S |
| Canada | Rimouski | Blier Pierre U |
| Canada | Antigonish | Kane Daniel A |
| Canada | Rimouski | Vandermeeren E |
| Canada | Vancouver | Boushel Robert C |
| Canada | Edmonton (Alberta) | Lemieux Helene |
| Croatia | Zagreb | Saric A |
| Croatia | Split | Mihanovic I |
| Czech Republic | Prague | Elkalaf Moustafa |
| Czech Republic | Pilsen | Kuncova J |
| Czech Republic | Hradec Králové | Waldauf P |
| Czech Republic | Pilsen | Markova Michaela |
| Czech Republic | Prague 10 | Krajcova Adela |
| Denmark | Copenhagen | Larsen Steen |
| Denmark | Copenhagen N | Mortensen OH |
| Denmark | Hvidovre | Nehlin Jan O |
| Denmark | Copenhagen | Gonzalez-Franquesa Alba |
| Denmark | Malov | Hey-Mogensen M |
| Denmark | Copenhagen | Dela Flemming |
| Estonia | Tallinn | Kaambre Tuuli |
| Estonia | Tallinn | Vendelin Marko |
| Estonia | Tallinn | Tepp Kersti |
| Estonia | Tallinn | Aid-Vanakova Jekaterina |
| Estonia | Tallinn | Karro N |
| Estonia | Tartu | Paju Kalju |
| Estonia | Tallinn | Puurand Marju |
| Estonia | Tallinn | Truu Laura |
| Finland | Helsinki | Pirinen E |
| Finland | Jyvaeskylae | Lehti Maarit |
| France | Grenoble Cedex 9 | Schlattner Uwe |
| France | Montpellier Cedex 1 | Chabi Beatrice |
| France | Paris | Ventura-Clapier R |
| France | Grenoble cedex 9 | Dubouchaud Herve |
| France | Montpellier | Cortade F |
| France | Paris | Armand Anne-Sophie |
| France | Paris | Petit Patrice X |
| France | Bordeaux cedex | Mourier A |
| Germany | Bremerhaven | Mark Felix Christopher |
| Germany | Rostock | Haider F |
| Germany | Cologne | Pesta Dominik |
| Germany | Nuthetal | Klaus S |
| Germany | Munich | Jastroch M |
| Germany | Bochum | Platen P |
| Germany | Düsseldorf | Granata Cesare |
| Germany | Duesseldorf | Jelenik T |
| Germany | Köln | Kimoloi Sammy |
| Germany | Duesseldorf | Roden Michael |
| Germany | Leipzig | Ost Mario |
| Greece | Heraklion | Tavernarakis Nektarios |
| Greece | Heraklio | Sidiropoulou K |
| Greece | Athens | Trougakos Ioannis P |
| India | Haryana | Sharma Vipin |
| Ireland | Dublin | O'Gorman Donal |
| Ireland | Dublin | Porter Richard K |
| Ireland | Sligo | Murphy J |
| Israel | Jerusalem | Saada Reisch Ann |
| Israel | Rishon Le Zion | Hachmo Yafit |
| Israel | Zrifin | Sova Marina |
| Italia | Udine | Salvadego Desy |
| Italy | Pisa | Gastaldelli Amalia |
| Italy | Rome | Scatena Roberto |
| Italy | Novara | Reano Simone |
| Italy | Milan | De Palma Clara |
| Italy | Milan | Giovarelli Matteo |
| Italy | Bologna | Genova Maria Luisa |
| Japan | Sapporo | Nambu H |
| Japan | Sapporo | Maekawa S |
| Japan | Sapporo | Shirakawa R |
| Latvia | Riga | Kuka Janis |
| Latvia | Riga | Zvejniece Liga |
| Latvia | Riga | Inashkina I |
| Latvia | Riga | Liepins Edgars |
| Luxembourg | Strassen | Devaux Yvan |
| Malta | Msida | Vella Joanna |
| Netherlands | BT Amsterdam | Jaspers Richard T |
| Netherlands | Maastricht | Van Polanen N |
| Netherlands | Wageningen | Keijer Jaap |
| Netherlands | Amsterdam | De Goede Paul |
| Netherlands | Maastricht | Grevendonk L |
| Netherlands | Maastricht | Hoeks Joris |
| Niederlande | ER Masstricht | De Wit-Verheggen V |
| Niederlande | ER Masstricht | De Theije C |
| Norway | Bergen | Tronstad Karl Johan |
| Norway | Oslo | Eide L |
| Norway | Tromsoe | Larsen Terje S |
| Norway | Tromsoe | Schots Pauke C |
| Norway | Tromsoe | Aasum E |
| Norway | Ullevål | Heiestad Christina |
| Norway | Oslo | Lund Jenny |
| Norway | Oslo | Nikolic N |
| Norway | Oslo | Torp May-Kristin |
| Norway | Oslo | Rustan AC |
| Norway | Tromsoe | Jansen Kirsten M |
| Poland | Warsaw | Sek Aleksandra |
| Poland | Warsaw | Kampa Rafal Pawel |
| Poland | Warsaw | Dymkowska Dorota |
| Poland | Lodz | Watala Cezary |
| Poland | Lodz | Labieniec-Watala Magdalena |
| Portugal | Porto | Beleza Jorge |
| Portugal | Cantanhede | Martins Joao D |
| Portugal | Coimbra | Palmeira Carlos |
| Portugal | Cantanhede | Ferreira LL |
| Portugal | Coimbra | Martins Marques T |
| Portugal | Porto | Coxito Pedro |
| Portugal | Coimbra | Carvalho Eugenia |
| Portugal | Porto | Magalhaes Jose |
| Portugal | Coimbra | Pereira Susana P |
| Romania | Timisoara | Lighezan R |
| Romania | Timisoara | Muntean Danina M |
| Singapore | Singapore | Hausenloy Derek J |
| Slovakia | Bratislava | Ukropcova B |
| Slovakia | Bratislava | Maderova D |
| Slovakia | Bratislava | Nemec Michal |
| Slovakia | Bratislava | Ukropec J |
| Slovakia | Bratislava | Sumbalova Zuzana |
| Slovenia | Ljubljana | Pirkmajer Sergej |
| Slovenia | Ljubljana | Dolinar K |
| Slovenia | Ljubljana | Mars T |
| South Africa | Smith James | |
| Spain | Madrid | Moran M |
| Spain | Barcelona | Sebastian D |
| Spain | Madrid | Cadenas S |
| Spain | Barcelona | Catalan M |
| Spain | Barcelona | De la Torre Lara J |
| Spain | Sevilla | Bustos Matilde |
| Spain | Barcelona | Zorzano Antonio |
| Spain | Barcelona | Batlle M |
| Spain | Armilla (Granada) | Fernandez-Ortiz Marisol |
| Spain | Barcelona | Gama Perez Pau |
| Spain | Armilla (Granada) | Acuna-Castroviejo Dario |
| Spain | A Coruña | Blanco FJ |
| Spain | Barcelona | Guitart M |
| Spain | Armilla, Granada | Escames Germaine |
| Spain | Barcelona | Garcia-Roves Pablo Miguel |
| Spain | Granada | Lopez Garcia Luis Carlos |
| Sweden | Linköping | Fontes-Oliveira CC |
| Sweden | Stockholm | Cardinale Daniele A |
| Switzerland | Lausanne | Gebara E |
| Switzerland | Lausanne | Morato Fornaguera L |
| Switzerland | Lausanne | Sandi Carmen |
| Switzerland | Lausanne | Weger M |
| Switzerland | Bern | Nuoffer Jean-Marc |
| Switzerland | Lausanne | Zalachoras I |
| The Netherlands | Wageningen | Van der Ende Miranda |
| The Netherlands | BT Amsterdam | Wuest Rob CI |
| Turkey | Ankara | Tuncay Erkan |
| USA | Torrance | Rossiter Harry B |
| USA | Chicago | Dayanidhi Sudarshan |
| USA | Fort Collins | Chicco Adam J |
| USA | Baton Rouge | Irving Brian A |
| USA | Fairbanks | O'Brien Kristin |
| USA | Baltimore | Gonzalez-Freire Marta |
| USA | College Station | White-Springer Sarah H |
| USA | Baltimore | Fang Evandro F |
| USA | Colorado Springs | Jacobs RA |
| USA | Ann Arbor | Beard Daniel A |
| USA | Norfolk | Lai Nicola |
| USA | Gainesville | Hepple Russell T |
| USA | Orlando | Distefano Giovanna |
| USA | St Louis | Welch R |
| USA | College Station | Latham C |
| USA | Gainesville | Neyroud D |
| USA | Boca Raton | Khamoui Andy V |
| USA | Little Rock | Porter Craig |
| USA | Baton Rouge | Axelrod Christopher L |
| USA | Orlando | Coen Paul M |
| USA | Gainesville | Wohlgemuth Stephanie E |
| United Kingdom | Birmingham | Garten Antje |
| United Kingdom | Birmingham | Thakker A |
| United Kingdom | Loughborough | Ebanks Brad |
| United Kingdom | Nottingham | Chakrabarti Lisa |
| United Kingdom | Plymouth, Devon | McKenna Helen T |
| United Kingdom | Leeds | Boyle JP |
| United Kingdom | Birmingham | Ashcroft S |
| United Kingdom | Cambridge | Shiroma Jonathan G |
| United Kingdom | Oxford | Makrecka-Kuka Marina |
| United Kingdom | Brighton | Moore Anthony L |
| United Kingdom | Cambridge | Murray Andrew James |
| United Kingdom | Birmingham | Joanisse S |
| United Kingdom | Manchester | Giakoumaki I |
| United Kingdom | London | Szabadkai Gyorgy |
| United States | Providence | Siamwala J |
WG2 Management
Tasks
- Call for participating labs to deliver relevant experimental data on already published studies and to report them in a standardized format.
- Collection and indexing of the data sets as required for statistical analysis.
- Discussion of procedures, protocols and general guidelines.
- Draft a comprehensive review on mt-function in muscle tissue (registration at PROSPERO, link with EQUATOR).
- Opening of the database to the research public for data search and moderated entry of new data sets.
Milestones
- Call for data report delivered.
- Data sets entered in standardized format.
- Summary, interpretation and discussion of data for review.
Deliverables
- A MITOEAGLE database on muscle tissue from humans and model organisms.
- A set of guidelines for future studies on mitochondrial bioenergetics in muscle tissue.
- Draft of review manuscript.
Projects in progress
- » MiPMap
