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From Bioblast
Year | Reference | Coupling | Pathway | Preparation | Organism | Tissue;cell | |
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Lee 2022 Hum Mol Genet | 2022 | Lee RG, Balasubramaniam S, Stentenbach M, Kralj T, McCubbin T, Padman B, Smith J, Riley LG, Priyadarshi A, Peng L, Nuske MR, Webster R, Peacock K, Roberts P, Stark Z, Lemire G, Ito YA; Care4Rare Canada Consortium, Boycott KM, Geraghty MT, van Klinken JB, Ferdinandusse S, Zhou Y, Walsh R, Marcellin E, Thorburn DR, Rosciolli T, Fletcher J, Rackham O, Vaz FM, Reid GE, Filipovska A (2022) Deleterious variants in CRLS1 lead to cardiolipin deficiency and cause an autosomal recessive multi-system mitochondrial disease. https://doi.org/10.1093/hmg/ddac040 | LEAK OXPHOS | N CIV ROX | Permeabilized cells | Human | Fibroblast |
Lehto 2022 Neurochem Res | 2022 | Lehto A, Koch K, Barnstorf-Brandes J, Viel C, Fuchs M, Klein J (2022) ß-Hydroxybutyrate improves mitochondrial function after transient ischemia in the mouse. https://doi.org/10.1007/s11064-022-03637-6 | LEAK OXPHOS ET | N S CIV NS ROX | Isolated mitochondria | Mouse | Nervous system |
Leman 2015 Int J Biochem Cell Biol | 2015 | Leman G, Gueguen N, Desquiret-Dumas V, Kane MS, Wettervald C, Chupin S, Chevrollier A, Lebre AS, Bonnefont JP, Barth M, Amati-Bonneau P, Verny C, Henrion D, Bonneau D, Reynier P, Procaccio V (2015) Assembly defects induce oxidative stress in inherited mitochondrial complex I deficiency. Int J Biochem Cell Biol 65:91-103. | N S CIV | Permeabilized cells | Human | Endothelial;epithelial;mesothelial cell Fibroblast | |
Lemieux 2011 Int J Biochem Cell Biol | 2011 | Lemieux H, Semsroth S, Antretter H, Höfer D, Gnaiger E (2011) Mitochondrial respiratory control and early defects of oxidative phosphorylation in the failing human heart. Int J Biochem Cell Biol 43:1729–38. https://doi.org/10.1016/j.biocel.2011.08.008 | LEAK OXPHOS ET | F N S CIV NS ROX | Permeabilized tissue | Human | Heart |
Lemieux 2013 Abstract MiP2013 | Lemieux H, Warren BE, Lucchinetti E, Lou PH, Zhang L, Gandhi M, Clanachan AS, Zaugg M(2013) Early mitochondrial dysfunction associated with type 2 diabetes mellitus in the heart and skeletal muscle. Mitochondr Physiol Network 18.08. | OXPHOS | F N S CIV NS Other combinations | Permeabilized tissue | Rat | Heart Skeletal muscle | |
Lemieux 2017 MiP2017 | Compounding effects of age and sexual dimorphism on cardiac mitochondrial function in type 2 diabetes. | OXPHOS | F CIV | Permeabilized tissue | Rat | Heart | |
Lemieux 2019 bioRxiv | 2019 | Lemieux H, Subarsky P, Doblander C, Wurm M, Troppmair J, Gnaiger E (2019) Mitochondrial respiratory function as an early biomarker of apoptosis induced by growth factor removal. bioRxiv doi: https://doi.org/10.1101/151480 . | LEAK ROUTINE OXPHOS ET | N S CIV NS ROX | Permeabilized cells Intact cells | Mouse | Blood cells |
Lemieux 2019a MiP2019 | Partial prevention of oxidative stress damage to mitochondria with photobiomodulation. | LEAK OXPHOS ET | N S CIV NS | Other invertebrates | |||
Leo 2017 Front Zool | 2017 | Leo E, Kunz KL, Schmidt M, Storch D, Portner HO, Mark FC (2017) Mitochondrial acclimation potential to ocean acidification and warming of Polar cod (Boreogadus saida) and Atlantic cod (Gadus morhua). Front Zool 14:21. | LEAK OXPHOS ET | CIV NS ROX | Permeabilized tissue | Fishes | Heart |
Leucci 2016 Nature | 2016 | Leucci E, Vendramin R, Spinazzi M, Laurette P, Fiers M, Wouters J, Radaelli E, Eyckerman S, Leonelli C, Vanderheyden K, Rogiers A, Hermans E, Baatsen P, Aerts S, Amant F, Van Aelst S, van den Oord J, de Strooper B, Davidson I, Lafontaine DL, Gevaert K, Vandesompele J, Mestdagh P, Marine JC (2016) Melanoma addiction to the long non-coding RNA SAMMSON. Nature 531:518-22. | LEAK OXPHOS ET | N CIV NS ROX | Permeabilized cells | Human | Endothelial;epithelial;mesothelial cell Other cell lines |
Li 2013 Free Radic Biol Med | 2013 | Li H, Kumar Sharma L, Li Y, Hu P, Idowu A, Liu Danhui, Lu J, Bai Y (2013) Comparative bioenergetic study of neuronal and muscle mitochondria during aging. Free Radic Biol Med 63:30-40. | LEAK ET | N S CIV | Intact cells | Mouse | Skeletal muscle Nervous system |
Li 2018 Free Radic Biol Med | 2018 | Li H, Tang Z, Chu P, Song Y, Yang Y, Sun B, Niu M, Qaed E, Shopit A, Han G, Ma X, Peng J, Hu M, Tang Z (2018) Neuroprotective effect of phosphocreatine on oxidative stress and mitochondrial dysfunction induced apoptosis in vitro and in vivo: Involvement of dual PI3K/Akt and Nrf2/HO-1 pathways. Free Radic Biol Med 120:228-38. | LEAK ROUTINE ET | CIV | Intact cells | Rat | Nervous system Other cell lines |
Li 2019 Int Urol Nephrol | 2019 | Li Z, Zhou J, Li Y, Yang F, Lian X, Liu W (2019) Mitochondrial TRPC3 promotes cell proliferation by regulating the mitochondrial calcium and metabolism in renal polycystin-2 knockdown cells. Int Urol Nephrol 51:1059-70. | ROUTINE OXPHOS ET LEAK | N S CIV NS ROX | Intact cells Permeabilized cells | Human | Endothelial;epithelial;mesothelial cell |
Liang 2021 Biomed Pharmacother | 2021 | Liang L, Zhang G, Cheng C, Li H, Jin T, Su C, Xiao Y, Bradley J, Peberdy MA, Ornato JP, Mangino MJ, Tang W (2021) High-resolution respirometry for evaluation of mitochondrial function on brain and heart homogenates in a rat model of cardiac arrest and cardiopulmonary resuscitation. Biomed Pharmacother 142:111935. | LEAK OXPHOS ROUTINE | N S CIV ROX | Homogenate | Rat | Heart Nervous system |
Liepinsh 2020 Physiol Rep | 2020 | Liepinsh E, Makarova E, Plakane L, Konrade I, Liepins K, Videja M, Sevostjanovs E, Grinberga S, Makrecka-Kuka M, Dambrova M (2020) Low-intensity exercise stimulates bioenergetics and increases fat oxidation in mitochondria of blood mononuclear cells from sedentary adults. Physiol Rep 8:e14489. | LEAK ROUTINE OXPHOS | F N CIV | Permeabilized cells Intact cells | Human | Blood cells |
Liu 2020 Cell Death Dis | 2020 | Liu YF, Zhu Juan-Juan, Yu Tian X, Liu Han, Zhang Tao, Zhang Yun-Peng, Xie Si-An, Zheng Ming, Kong Wei, Yao Wei-Juan, Pang Wei, Zhao Chuan-Rong, Tang Yuan-Jun, Zhou Jing (2020) Hypermethylation of mitochondrial DNA in vascular smooth muscle cells impairs cell contractility. Cell Death Dis 11:35. | LEAK OXPHOS | N S CIV ROX | Permeabilized tissue | Mouse | Endothelial;epithelial;mesothelial cell |
Liu 2021 Basic Res Cardiol | 2021 | Liu N, Kataoka M, Wang Y, Pu L, Dong X, Fu X, Zhang F, Gao F, Liang T, Pei J, Xiao C, Qiu Q, Hong T, Chen Q, Zhao J, Zhu L, He J, Hu X, Nie Y, Zhu W, Yu H, Cowan DB, Hu X, Wang J, Wang DZ, Chen J (2021) LncRNA LncHrt preserves cardiac metabolic homeostasis and heart function by modulating the LKB1-AMPK signaling pathway. Basic Res Cardiol 116:48. | OXPHOS | F N S CIV ROX | Permeabilized tissue | Mouse | Heart |
Liu 2022 Adv Sci (Weinh) | 2022 | Liu H, Liu Y, Wang H, Zhao Q, Zhang T, Xie SA, Liu Y, Tang Y, Peng Q, Pang W, Yao W, Zhou J (2022) Geometric constraints regulate energy metabolism and cellular contractility in vascular smooth muscle cells by coordinating mitochondrial DNA methylation. https://doi.org/10.1002/advs.202203995 | LEAK OXPHOS | N S CIV ROX | Permeabilized cells | Human | Other cell lines |
Ljones 2017 PLOS ONE | 2017 | Ljones K, Ness HO, Solvang-Garten K, Gaustad SE, Andre Høydal M (2017) Acute exhaustive aerobic exercise training impair cardiomyocyte function and calcium handling in Sprague-Dawley rats. PLOS ONE 12:e0173449. | OXPHOS ET LEAK | N S CIV NS ROX | Permeabilized tissue | Rat | Heart |
Long 2019 Methods Mol Biol | 2019 | Long Q, Huang L, Huang K, Yang Q (2019) Assessing mitochondrial bioenergetics in isolated mitochondria from mouse heart tissues using Oroboros Oxygraph-2k. Methods Mol Biol 1966:237-46. | LEAK OXPHOS ET | N S CIV NS ROX | Isolated mitochondria | Mouse | Heart |
Lou 2014b PLoS One | 2014 | Lou PH, Lucchinetti E, Zhang L, Affolter A, Gandhi M, Hersberger M, Warren BE, Lemieux H, Sobhi HF, Clanachan AS, Zaugg M (2014) Loss of Intralipid®- but not sevoflurane-mediated cardioprotection in early type-2 diabetic hearts of fructose-fed rats: importance of ROS signaling. PLoS One 9:e104971. | LEAK | F N S CIV | Permeabilized tissue | Rat | Heart |
Lou 2017 Physiol Rep | 2017 | Lou PH, Lucchinetti E, Scott KY, Huang Y, Gandhi M, Hersberger M, Clanachan AS, Lemieux H, Zaugg M (2017) Alterations in fatty acid metabolism and sirtuin signaling characterize early type-2 diabetic hearts of fructose-fed rats. Physiol Rep 5 pii: e13388. | LEAK OXPHOS | F N CIV NS | Rat | Heart | |
Loureiro 2016 Oxid Med Cell Longev | 2016 | Loureiro AC, do Rêgo-Monteiro IC, Louzada RA, Ortenzi VH, de Aguiar AP, de Abreu ES, Cavalcanti-de-Albuquerque JP, Hecht F, de Oliveira AC, Ceccatto VM, Fortunato RS, Carvalho DP (2016) Differential expression of NADPH oxidases depends on skeletal muscle fiber type in rats. Oxid Med Cell Longev 2016:6738701. | LEAK OXPHOS | N CIV NS ROX | Permeabilized tissue | Rat | Skeletal muscle |
Luethi 2017 Toxicology | 2017 | Luethi D, Liechti ME, Krähenbühl S (2017) Mechanisms of hepatocellular toxicity associated with new psychoactive synthetic cathinones. Toxicology 387:57-66. | OXPHOS ET | NS N S DQ CIV ROX | Permeabilized cells | Human | Liver |
Luevano-Martinez 2019 Fungal Biol | 2019 | Luévano-Martínez LA, Caldeira da Silva CC, Nicastro GG, Schumacher RI, Kowaltowski AJ, Gomes SL (2019) Mitochondrial alternative oxidase is determinant for growth and sporulation in the early diverging fungus Blastocladiella emersonii. Fungal Biol 123:59-65. | ET | ROX CIV | Intact cells | Fungi | |
Lund 2016 J Physiol | 2016 | Lund MT, Kristensen M, Hansen M, Tveskov L, Floyd AK, Støckel M, Vainer B, Poulsen SS, Helge JW, Prats C, Dela F (2016) Hepatic mitochondrial oxidative phosphorylation is normal in obese patients with and without type 2 diabetes. J Physiol 594:4351-8. | LEAK OXPHOS ET | F N S CIV NS ROX | Permeabilized tissue | Human | Liver |
Luptak 2023 Antioxidants (Basel) | 2023 | Ľupták M, Fišar Z, Hroudová J (2023) Different effects of SSRIs, Bupropion, and Trazodone on mitochondrial functions and monoamine oxidase isoform activity. Antioxidants (Basel) 12:1208. https://doi.org/10.3390/antiox12061208 | N S CIV NS | Isolated mitochondria Oxidase;biochemical oxidation | Pig | Nervous system | |
Maarman 2016 J Appl Physiol (1985) | 2016 | Maarman GJ, Andrew BM, Blackhurst DM, Ojuka EO (2016) Melatonin protects against uric acid-induced mitochondrial dysfunction, oxidative stress, and triglyceride accumulation in C2C12 myotubes. J Appl Physiol (1985) 122:1003-10. | LEAK ROUTINE OXPHOS ET | N S CIV NS ROX | Permeabilized cells Intact cells | Mouse | Skeletal muscle |
MacMillan 2017 Front Physiol | 2017 | MacMillan NJ, Kapchinsky S, Konokhova Y, Gouspillou G, de Sousa Sena R, Jagoe RT, Baril J, Carver TE, Andersen RE, Richard R, Perrault H, Bourbeau J, Hepple RT, Taivassalo T (2017) Eccentric ergometer training promotes locomotor muscle strength but not mitochondrial adaptation in patients with severe chronic obstructive pulmonary disease. Front Physiol 8:114. | OXPHOS | N CIV NS ROX | Permeabilized tissue | Human | Skeletal muscle |
Macedo 2019 Biochim Biophys Acta Mol Cell Biol Lipids | 2019 | Macedo F, Martins GL, Luévano-Martínez LA, Viana GM, Riske KA, Inague A, Yoshinaga MY, Aguilaniu H, Miyamoto S, Glezer I, da Cunha FM (2019) Lipase-like 5 enzyme controls mitochondrial activity in response to starvation in Caenorhabditis elegans. Biochim Biophys Acta Mol Cell Biol Lipids 1865:158539. | LEAK OXPHOS | N CIV NS | Isolated mitochondria | Caenorhabditis elegans | |
Macedo 2020 FASEB J | 2020 | Macedo F, Romanatto T, Gomes de Assis C, Buis A, Kowaltowski AJ, Aguilaniu H, Marques da Cunha F (2020) Lifespan-extending interventions enhance lipid-supported mitochondrial respiration in Caenorhabditis elegans. FASEB J 34:9972-81. | LEAK OXPHOS | F N CIV ROX | Intact organism Isolated mitochondria | Caenorhabditis elegans | |
Madlala 2019 Integr Food Nutr Metab | 2019 | Madlala HP, Maarman GJ, Ojuka E (2019) Fructose impairs mitochondrial respiration and substrate utilization in hepatocytes via the enzyme, glutamate oxaloacetate transaminase. Integr Food Nutr Metab doi: 10.15761/IFNM.1000228. | LEAK OXPHOS ET | N CIV ROX | Permeabilized cells | Human | Liver |
Magnifico 2017 Oxid Med Cell Longev | 2017 | Magnifico MC, Oberkersch RE, Mollo A, Giambelli L, Grooten Y, Sarti P, Calabrese GC, Arese M (2017) VLDL induced modulation of nitric oxide signalling and cell redox homeostasis in HUVEC. Oxid Med Cell Longev 2017:2697364. | OXPHOS | N S CIV | Permeabilized cells | Human | Endothelial;epithelial;mesothelial cell |
Magnifico 2018 Oxid Med Cell Longev | 2018 | Magnifico MC, Xhani M, Popov M, Saso L, Sarti P, Arese M (2018) Nonylphenol and octylphenol differently affect cell redox balance by modulating the nitric oxide signaling. Oxid Med Cell Longev 2018:1684827. | ROUTINE OXPHOS | N S CIV ROX | Permeabilized cells Intact cells | Human | Liver Other cell lines |
Mahalingam 2017 J Physiol | 2017 | Mahalingam S, McClelland GB, Scott GR (2017) Evolved changes in the intracellular distribution and physiology of muscle mitochondria in high-altitude native deer mice. J Physiol 595:4785-801. | LEAK OXPHOS | N CIV NS | Permeabilized tissue Isolated mitochondria | Mouse | Skeletal muscle |
Mahalingam 2020 J Physiol | 2020 | Mahalingam S, Cheviron ZA, Storz JF, McClelland GB, Scott GR (2020) Chronic cold exposure induces mitochondrial plasticity in deer mice native to high altitudes. J Physiol 598:5411-26. https://doi.org/10.1113/JP280298 | LEAK OXPHOS | F N S CIV NS | Isolated mitochondria | Mouse | Skeletal muscle |
Mahapatra 2024 J Gerontol A Biol Sci Med Sci | 2024 | Mahapatra G, Gao Z, Bateman JR 3rd, Lockhart SN, Bergstrom J, Piloso JE, Craft S, Molina AJA (2024) Peripheral blood cells from older adults exhibit sex-associated differences in mitochondrial function. J Gerontol A Biol Sci Med Sci [Epub ahead of print]. https://doi.org/10.1093/gerona/glae098 | ROUTINE OXPHOS ET | F N Gp CIV NS Other combinations ROX | Permeabilized cells Intact cells | Human | Blood cells |
Makrecka-Kuka 2017 Toxicol Lett | 2017 | Makrecka-Kuka M, Volska K, Antone U, Vilskersts R, Grinberga S, Bandere D, Liepinsh E, Dambrova M (2017) Trimethylamine N-oxide impairs pyruvate and fatty acid oxidation in cardiac mitochondria. Toxicol Lett 267:32-8. | LEAK OXPHOS ET | F N S CIV NS ROX | Permeabilized tissue | Mouse | Heart |
Mandic 2022 J Comp Physiol B | 2022 | Mandic M, Frazier AJ, Naslund AW, Todgham AE (2022) A comparative and ontogenetic examination of mitochondrial function in antarctic notothenioid species. https://doi.org/10.1007/s00360-022-01461-6 | LEAK OXPHOS ET | N S CIV NS ROX | Permeabilized tissue | Fishes | Heart |
Mandò 2014 Am J Physiol Endocrinol Metab | 2014 | Mandò C, De Palma C, Stampalija T, Anelli GM, Figus M, Novielli C, Parisi F, Clementi E, Ferrazzi E, Cetin I (2014) Placental mitochondrial content and function in intrauterine growth restriction and preeclampsia. Am J Physiol Endocrinol Metab 306:E404-13. | ROUTINE OXPHOS | N S CIV NS ROX | Intact cells Permeabilized cells | Human | Genital |
Mann 2019 Oncogene | 2019 | Mann J, Githaka JM, Buckland TW, Yang N, Montpetit R, Patel N, Li L, Baksh S, Godbout R, Lemieux H, Goping IS (2019) Non-canonical BAD activity regulates breast cancer cell and tumor growth via 14-3-3 binding and mitochondrial metabolism. Oncogene 38:3325-39. | LEAK ROUTINE OXPHOS ET | N S CIV NS ROX F | Permeabilized cells Intact cells | Human | Endothelial;epithelial;mesothelial cell |
Mark 2012 Abstract Bioblast | Mark FC, Strobel A, Poertner HO (2012) Ocean warming and acidification – when fish mitochondria turn sour. Mitochondr Physiol Network 17.12. | LEAK ROUTINE OXPHOS | N S CIV NS | Permeabilized tissue Isolated mitochondria | Fishes | Heart Liver | |
Markova 2017 MiP2017 | Porcine sepsis and associated myocardial depression. | LEAK OXPHOS | N S CIV NS ROX | Pig | Heart | ||
Markova 2017 MiPschool Obergurgl | Mitochondrial respiration in the rat left heart ventricle after inhibition of pyruvate dehydrogenase kinase. | LEAK OXPHOS | N S CIV NS ROX | Homogenate | Rat | Heart | |
Marquez 2020 J Am Heart Assoc | 2020 | Marquez AM, Morgan RW, Ko T, Landis WP, Hefti MM, Mavroudis CD, McManus MJ, Karlsson M, Starr J, Roberts AL, Lin Y, Nadkarni V, Licht DJ, Berg RA, Sutton RM, Kilbaugh TJ (2020) Oxygen exposure during cardiopulmonary resuscitation is associated with cerebral oxidative injury in a randomized, blinded, controlled, preclinical trial. J Am Heart Assoc 9:015032. | LEAK OXPHOS ET | N S CIV NS | Homogenate | Pig | Nervous system |
Martell 2023 Nat Commun | 2023 | Martell E, Kuzmychova H, Kaul E, Senthil H, Chowdhury SR, Morrison LC, Fresnoza A, Zagozewski J, Venugopal C, Anderson CM, Singh SK, Banerji V, Werbowetski-Ogilvie TE, Sharif T (2023) Metabolism-based targeting of MYC via MPC-SOD2 axis-mediated oxidation promotes cellular differentiation in group 3 medulloblastoma. https://doi.org/10.1038/s41467-023-38049-9 | LEAK ROUTINE OXPHOS ET | N S CIV ROX | Permeabilized cells Intact cells | Human | Nervous system |
Mathers 2017 J Comp Physiol B | 2017 | Mathers KE, McFarlane SV, Zhao L, Staples JF (2017) Regulation of mitochondrial metabolism during hibernation by reversible suppression of electron transport system enzymes. J Comp Physiol B 187:227-34. | LEAK OXPHOS | N S CIV ROX DQ | Intact cells Isolated mitochondria | Other mammals | Liver |
Mavroudis 2018 Eur J Cardiothorac Surg | 2018 | Mavroudis CD, Karlsson M, Ko T, Hefti M, Gentile JI, Morgan RW, Plyler R, Mensah-Brown KG, Boorady TW, Melchior RW, Rosenthal TM, Shade BC, Schiavo KL, Nicolson SC, Spray TL, Sutton RM, Berg RA, Licht DJ, Gaynor JW, Kilbaugh TJ (2018) Cerebral mitochondrial dysfunction associated with deep hypothermic circulatory arrest in neonatal swine. Eur J Cardiothorac Surg 54:162-68. | LEAK ET OXPHOS | N S CIV NS ROX | Homogenate | Pig | Nervous system |
Mayeur 2013 PhD Thesis | 2013 | Mayeur S (2013) Retard de croissance intra-utérin et vulnérabilité au syndrome métabolique: recherche de marqueurs placentaires dans un modèle de dénutrition maternelle prénatale et chez l'Homme. PhD Thesis 1-225. | LEAK OXPHOS ET | N S CIV NS ROX | Isolated mitochondria | Rat | Genital |
McBride 2019 Arch Biochem Biophys | 2019 | McBride S, Wei-LaPierre L, McMurray F, MacFarlane M, Qiu X, Patten DA, Dirksen RT, Harper ME (2019) Skeletal muscle mitoflashes, pH, and the role of uncoupling protein-3. Arch Biochem Biophys 663:239-48. | LEAK OXPHOS | F N CIV NS ROX | Permeabilized tissue | Mouse | Skeletal muscle |