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List of results

• SUIT-003 Ce1;ce3U-  + ([[File:1ce;3ceU-.jpg|150px]])
• SUIT-032 NADH mt D078  + ([[File:1mt;1PGM;2D;3Anox;4Myx;5Reox.png|300px]])
• Oxoglutarate  + ([[File:2-Oxoglutaric_acid.jpg|left|100px|2 … [[File:2-Oxoglutaric_acid.jpg|left|100px|2-Oxoglutaric acid]]</br>'''2-Oxoglutaric acid''' or alpha-ketoglutaric acid, C₅H₆O₅, occurs under physiological conditions as the anion '''2-Oxoglutarate^2-, Og'''. 2-Oxoglutarate (alpha-ketoglutarate) is formed from isocitrate as a product of [[isocitrate dehydrogenase]] (IDH) in the [[TCA cycle]], and is a substrate of [[oxoglutarate dehydrogenase]] (OgDH). The 2-oxoglutarate carrier exchanges malate^2- for 2-oxoglutarate^2- as part of the [[malate-aspartate shuttle]]. In the cytosol, oxoglutarate+aspartate are transaminated to form oxaloacetate+glutamate. Cytosolic malate dehydrogenase converts oxaloacetate+NADH to malate.transaminated to form oxaloacetate+glutamate. Cytosolic malate dehydrogenase converts oxaloacetate+NADH to malate.)
• Mitochondria-Targeted Drug Development  + ([[File:21640 - Mitochondria Targeted Thera … [[File:21640 - Mitochondria Targeted Therapeutics logo NEW.jpg|200px|left|Mitochondria-Targeted Drug Development]]</br>The '''Mitochondria-Targeted Drug Development Summit''' was first established in 2021, as an online conference. Due to its success and unmatched focus, the 2^nd edition returns to Boston this March 2022. </br>This is the only industry-led meeting that unites key stakeholders under a mutual and ambitious objective of '''accelerating the discovery and development of novel drugs that target mitochondrial functions''' for chronic, primary mitochondrial diseases, muscular dystrophy, metabolic disorders, and neurodegenerative diseases.</br>Join our speakers from '''GenSight Biologics, Abliva, Reneo Pharma, Mito BioPharma, Mitokinin''' and more with exciting networking opportunities, panel discussions and dedicated roundtables.tunities, panel discussions and dedicated roundtables.)
• Screwdriver allen wrench  + ([[File:24330-02.jpg|right|180px]]'''Screwdriver allen wrench''', a standard component of the [[O2k-FluoRespirometer]] and [[O2k-sV-Module]].)
• MultiSensor-Connector  + ([[File:30420-24 MultiSensorConnector.JPG|right|180px]] '''MultiSensor-Connector''': for separate reference electrode and [[ISE]]; only for O2k-Series B and Series C with MultiSensor electronic upgrading before 2011.)
• MultiSensor-Preamplifier 1/100  + ([[File:30430--24 NO-Attachment.JPG|right|180px]] '''MultiSensor-Preamplifier 1/100''': Required only for O2k-Series A-C, for application of NO (or other amperometric) sensors (single chamber mode of application).)
• TIP2k-Needle Safety Support with cable guide  + ([[File:31330-01 3.jpg|right|280px]] '''TIP2k-Needle Safety Support with cable guide''': for safe storage of TIP2k-needles and MultiSensor Modules cables when not required during the experiment.)
• Storage box sV  + ([[File:32001-01.jpg|right|180px]]'''Storage box sV''' empty, for storage of [[O2k-sV-Module]] components.)
• O2k-Chamber Holder sV  + ([[File:32100-01.jpg|right|180px]]'''O2k-Chamber Holder sV''' (black POM) for PVDF or PEEK stoppers (0.5-mL [[O2k-chamber]]), with [[O-ring\Viton\16x2 mm]] and [[V-ring\30-35-4.5 mm]].)
• POS-Holder sV  + ([[File:32300-01.jpg|right|180px]] '''POS-H … [[File:32300-01.jpg|right|180px]]</br>'''POS-Holder sV''', made from black POM, to be screwed into the copper block of the [[O2k-Main Unit]], guiding the [[OroboPOS|POS]] to the [[O2k-Chamber sV]], and keeping the SmartPOS/OroboPOS-Connector in a fixed position for sealing the O2k-Chamber sV with the [[POS-Seal Tip]]. In addition, the POS-Holder sV fixes the O2k-Chamber sV in an accurate rotational position by pressing against the angular cut of the glass chamber.inst the angular cut of the glass chamber.)
• O2k-Chamber sV  + ([[File:33100-01.jpg|right|180px]]'''O2k-Chamber sV''': 12 mm inner diameter, Duran® glass polished, with standard operation volume ''V'' of 0.5 mL.)
• Stirrer-Bar sV\white PVDF\11.5x6.2 mm  + ([[File:33210-01.jpg|right|180px]]'''Stirre … [[File:33210-01.jpg|right|180px]]'''Stirrer-Bar sV\white [[PVDF]]\11.5x6.2 mm''', operated in the 0.5-mL [[O2k-Chamber sV]] at constant stirring speed (standard is 750 rpm, or 12.5 Hz), to provide optimum mixing of the sample in the aqueous medium and ensure a stable signal of the polarographic oxygen sensor ([[OroboPOS]]) placed in a position of maximum current of the medium.position of maximum current of the medium.)
• Stopper sV\black PEEK\conical Shaft\central Port  + ([[File:34000-01.jpg|right|180px]]'''Stoppe … [[File:34000-01.jpg|right|180px]]'''Stopper sV\black PEEK\conical Shaft\central Port''': with conical shaft (with PTFE, graphite, carbon fiber) and one central capillary (1.0 mm diameter; 48.9 mm length), [[Volume-Calibration Ring sV]] (A or B) for volume adjustment 0.5 mL; 2 mounted O-rings ([[O-ring sV\Viton\9.5x1 mm]]).[[O-ring sV\Viton\9.5x1 mm]]).)
• O-ring sV\Viton\9.5x1 mm  + ([[File:34310-02.jpg|right|180px]]'''O-ring sV\[[Viton]]\9.5x1 mm''', for [[Stopper sV\black PEEK\conical Shaft\central Port | PEEK Stopper sV]], 2 are mounted on each PEEK Stopper sV, box of 8 as spares.)
• Asia Society for Mitochondrial Research and Medicine  + ([[File:ASMRM LOGO.JPG|200px|left]]The '''Asia Society for Mitochondrial Research and Medicine''' (ASMRM) was founded in 2003 to share the latest knowledge on mitochondrial research.)
• Acetyl-CoA  + ([[File:Acetyl coenzyme A 700.png|left|200p … [[File:Acetyl coenzyme A 700.png|left|200px|acetyl-CoA]]'''Acetyl-CoA''', C₂₃H₃₈N₇O₁₇P₃S, is a central piece in metabolism involved in several biological processes, but its main role is to deliver the acetyl group into the [[TCA cycle]] for its oxidation. It can be synthesized in different pathways: (i) in glycolysis from [[pyruvate]], by pyruvate dehydrogenase, which also forms NADH; (ii) from fatty acids β-oxidation, which releases one acetyl-CoA each round; (iii) in the catabolism of some amino acids such as leucine, lysine, phenylalanine, tyrosine and tryptophan.</br><br>In the mitochondrial matrix, acetyl-CoA is condensed with [[oxaloacetate]] to form [[citrate]] through the action of [[citrate synthase]] in the [[tricarboxylic acid cycle]]. Acetyl-CoA cannot cross the mitochondrial inner membrane but citrate can be transported out of the mitochondria. In the cytosol, citrate can be converted to acetyl-CoA and be used in the synthesis of fatty acid, cholesterol, ketone bodies, acetylcholine, and other processes. and be used in the synthesis of fatty acid, cholesterol, ketone bodies, acetylcholine, and other processes.)
• Aconitase  + ([[File:Aconitase.jpg|right|500px|aconitase … [[File:Aconitase.jpg|right|500px|aconitase]]'''Aconitase''' is a [[TCA cycle]] enzyme that catalyzes the reversible isomerization of [[citrate]] to [[isocitrate]]. Also, an isoform is also present in the cytosol acting as a trans-regulatory factor that controls iron homeostasis at a post-transcriptional level.<br>tasis at a post-transcriptional level.<br>)
• Cardiovascular Exercise Research Group  + ([[File:CERG.gif|200px|left|CERG]] The '''C … [[File:CERG.gif|200px|left|CERG]]</br>The '''Cardiovascular Exercise Research Group''' (CERG) was established in January 2008 and their research focuses on identifying the key cellular and molecular mechanisms underlying the beneficial effects of physical exercise on the heart, arteries and skeletal muscle in the context of disease prevention and management through experimental, clinical and epidemiological studies. </br>Since 2003 this research group organizes the biennial seminar [http://www.ntnu.edu/cerg/seminar-2013 "Exercise in Medicine"] in Trondheim, Norway.ercise in Medicine"] in Trondheim, Norway.)
• Complex II ambiguities  + ([[File:CII-ambiguities Graphical abstract. … [[File:CII-ambiguities Graphical abstract.png|300px|left|link=Gnaiger 2023 MitoFit CII]]The current narrative that the reduced coenzymes NADH and FADH2 feed electrons from the tricarboxylic acid (TCA) cycle into the mitochondrial electron transfer system can create ambiguities around respiratory Complex CII. Succinate dehydrogenase or CII reduces FAD to FADH2 in the canonical forward TCA cycle. However, some graphical representations of the membrane-bound electron transfer system (ETS) depict CII as the site of oxidation of FADH2. This leads to the false believe that FADH2 generated by electron transferring flavoprotein (CETF) in fatty acid oxidation and mitochondrial glycerophosphate dehydrogenase (CGpDH) feeds electrons into the ETS through CII. In reality, NADH and succinate produced in the TCA cycle are the substrates of Complexes CI and CII, respectively, and the reduced flavin groups FMNH2 and FADH2 are downstream products of CI and CII, respectively, carrying electrons from CI and CII into the Q-junction. Similarly, CETF and CGpDH feed electrons into the Q-junction but not through CII. The ambiguities surrounding Complex II in the literature call for quality control, to secure scientific standards in current communications on bioenergetics and support adequate clinical applications.nd support adequate clinical applications.)
• Complex II  + ([[File:CII.png |right|200px|link=Gnaiger 2 … [[File:CII.png |right|200px|link=Gnaiger 2023 MitoFit CII]]</br>'''Complex II''' or '''succinate:quinone oxidoreductase (SQR)''' is the only membrane-bound enzyme in the [[TCA cycle]] and is part of the [[electron transfer pathway]]. The reversible oxidoreduction of succinate and fumarate is catalyzed in a soluble domain and coupled to the reversible oxidoreduction of quinol and quinone in the mitochondrial inner membrane. CII consists in most species of four subunits. The flavoprotein [[succinate dehydrogenase]] is the largest polypeptide of CII, located on the matrix face of the mt-inner membrane. Succinate:quinone oxidoreductases (SQRs, SDHABCD) favour oxidation of succinate and reduction of quinone in the canonical forward direction of the TCA cycle and electron transfer into the [[Q-junction]]. In contrast, quinol:fumarate reductases (QFRs, fumarate reductases, FRDABCD) tend to operate in the reverse direction reducing fumarate and oxidizing quinol.on reducing fumarate and oxidizing quinol.)
• SUIT-007 O2 ce-pce D030  + ([[File:Ce1;1Dig;1G;2D;2c;3M;4U;5Ama.png|400px]])
• SUIT-027 O2 ce-pce D065  + ([[File:Ce1;1Dig;1M;2D;3M;4P;5G;6Ama.png|500px]])
• SUIT-006 O2 ce-pce D029  + ([[File:Ce1;1Dig;1PM;2D;2c;3Omy;4U;5Ama.png|600px]])
• SUIT-031 O2 ce-pce D079  + ([[File:Ce1;1Dig;1PM;2D;2c;3S;4Rot;5U;6Ama.png|400px]])

• SUIT-024  + ([[File:Ce1;1Dig;1PM;2T;2D;3Omy-.png|410px]])

• SUIT-024 O2 ce-pce D056  + ([[File:Ce1;1Dig;1PM;2T;2D;3Omy;4Ama.png|410px]])
• SUIT-031 Q ce-pce D074  + ([[File:Ce1;1Dig;1Q2;1PM;2D;3S;4Rot;5U;6Anox;7Ama.png|400px]])
• SUIT-009 O2 ce-pce D016  + ([[File:Ce1;1Dig;1S;2D;2c;3P;4Rot;5Ama.png|520px|SUIT-009]])
• SUIT-009 AmR ce-pce D019  + ([[File:Ce1;1Dig;1S;2D;3P;4Rot;5Ama.png|520px|SUIT9]])
• SUIT-026 AmR ce-pce D087  + ([[File:Ce1;1Dig;1S;2Rot;3D;4Ama.png|600px]])
• SUIT-018 AmR ce-pce D068  + ([[File:Ce1;1Dig;2GMS;3D;4Ama.png|290px]])
• SUIT-003 O2 ce D037  + ([[File:Ce1;ce1Glc;ce2(Omy);ce3U;ce4Ama.png|350px]])
• SUIT-003 O2 ce-pce D018  + ([[File:Ce1;ce1P;ce2Omy;ce3U;ce4Glc;ce5Rot;ce6S;1Dig;1U;1c;2Ama;3AsTm;4Azd.png|600px]])
• SUIT-003 O2 ce D012  + ([[File:Ce1;ce1P;ce2Omy;ce3U;ce4Rot;ce5Ama.png|400px]])
• SUIT-003 Ce1;ce1SD;ce3U;ce4Rot;ce5Ama  + ([[File:Ce1;ce1SD;ce3U;ce4Rot;ce5Ama.png|200px]])
• SUIT-003  + ([[File:Ce1;ce2(Omy);ce3U-.png|250px]] [[File:Ce5S;1Dig;1c-.png|250px]])
• SUIT-003 O2 ce D038  + ([[File:Ce1;ce2(Omy);ce3U;ce3Glc;ce3'U;ce4Ama.png|350px]])
• SUIT-003 Ce1;ce2U;ce3Rot;ce4S;ce5Ama  + ([[File:Ce1;ce2U;ce3Rot;ce4S;ce5Ama.png|200px]])
• SUIT-003 Ce1;ce3U;ce4Rot;ce5S;ce6Ama  + ([[File:Ce1;ce3U;ce4Rot;ce5S;ce6Ama.png|200px]])
• Cell Symposia  + ([[File:CellSymposiaLogo.jpg|90px]] Organized by the editors of Cell Press's leading journals, '''Cell Symposia''' bring together exceptional speakers and scientists to discuss topics at the forefront of scientific research.)
• Chemical background  + ([[File:Chb.png|100px|https://wiki.oroboros … [[File:Chb.png|100px|https://wiki.oroboros.at/index.php/File:Chb.png]] '''Chemical background''' ''Chb'' is due to autooxidation of the reagents. During CIV assays, ascorbate and TMPD are added to maintain cytochrome ''c'' in a reduced state. External cytochrome ''c'' may be included in the CIV assay. The autooxidation of these compounds is linearly oxygen-dependent down to approximately 50 µM oxygen and responsible for the chemical background oxygen flux after the inhibition of CIV. Oxygen flux due to the chemical reaction of autooxidation must be corrected for the [[Oxygen flux - instrumental background|instrumental O2 background]]. The correction for chemical background is necessary to determine CIV activity, in which case the instrumental O2 background and chemical background may be combined in an overall correction term.be combined in an overall correction term.)
• Citrate  + ([[File:Citrate 300 (1).png|left|100px|citr … [[File:Citrate 300 (1).png|left|100px|citrate]]'''citrate''', C₆H₅O₇^-3, is a tricarboxylic acid trianion, intermediate of the TCA cycle, obtained by deprotonation of the three carboxy groups of citric acid. Citrate is formed from [[oxaloacetate]] and acetyl-CoA through the catalytic activity of the [[citrate synthase]]. In the TCA cycle, citrate forms isocitrate by the activity of the [[aconitase]]. Citrate can be transported out of the mitochondria by the tricarboxylate transport, situated in the inner mitochondrial membrane. The transport occurs as an antiport of malate from the cytosol and it is a key process for fatty acid and oxaloacetate synthesis in the cytosol. <br>ol and it is a key process for fatty acid and oxaloacetate synthesis in the cytosol. <br>)
• Coenzyme Q2  + ([[File:Coenzyme Q2.png|left|200px|CoQ<s … [[File:Coenzyme Q2.png|left|200px|CoQ₂]]'''Coenzyme Q₂''' or ubiquinone-2 (CoQ₂) is a [[quinone]] derivate composed of a benzoquinone ring with an isoprenoid side chain consisting of two isoprenoid groups, with two methoxy groups, and with one methyl group. In HRR it is used as a Q-mimetic to detect the redox changes of [[coenzyme Q]] at the [[Q-junction]] in conjunction with the [[Q-Module]], since the naturally occurring long-chain coenzyme Q (e.g. CoQ₁₀) is trapped within membrane boundaries. CoQ₂ can react both with mitochondrial complexes (e.g. [[CI]], [[CII]] and [[CIII]]) at their quinone-binding sites and with the [[Three-electrode system |detecting electrode]].[[Three-electrode system |detecting electrode]].)
• Company of Scientists  + ([[File:Company-of-Scientists logo.jpg|left|140px|link=http://www.company-of-scientists.com|Company of Scientists]] The '''Company of Scientists''' evolves as a concept for implementing scientific innovations on the market.)
• Unit  + ([[File:Count-vs-number.png|right|120px|lin … [[File:Count-vs-number.png|right|120px|link=Elementary entity]]</br>A '''unit''' is defined as 'a single individual thing' in Euclid's ''Elements'' (Book VII). This defines the [[elementary entity]] ''U''_''X'' of entity-type ''X'' (thing). The [[International System of Units]] defines the unit as 'simply a particular example of the quantity concerned which is used as a reference'. Then the ''value'' of a quantity ''Q'' is the product of a number ''N'' and a unit ''u''_''Q''. The symbols ''U''_''X'' and ''u''_''Q'' are chosen here with ''U'' and ''u'' for 'unit': ''U''_''X'' is the Euclidean or entetic unit ('eunit'), and ''u''_''Q'' is the abstract unit ('aunit'). Subscripts ''X'' and ''Q'' for 'entity-type' and 'quantity-type' reflect perhaps even more clearly than words the contrasting meanings of the two fundamental definitions of an entetic versus abstract 'unit'. The term 'unit' with its dual meanings is used and confused in practical language and the scientific literature today. In the elementary entity ''U''_''X'', the unit (the 'one') relates to the entity-type ''X'', to the single individual thing (single individual or undivided; the root of the word ''thing'' has the meaning of 'assembly'). The quantity involved in the unit of a single thing is the ''count'', ''N''_''X'' = ''N''·''U''_''X'' [x]. In contrast to counting, a unit ''u''_''Q'' is linked to the measurement of quantities ''Q''_''u'' = ''N''·''u''_''Q'', such as volume, mass, energy; and these quantities — and hence the units ''u''_''Q'' — are abstracted from entity-types, pulled away from the world of real things. The new SI (2019-05-20) has completed this total abstraction of units, from the previous necessity to not only provide a quantitative definition but also a physical realization of a unit in the form of an 'artefact', such as the international prototype (IPK) for the unit kilogram. The new definitions of the base SI units are independent of any physical realization: ''u''_''Q'' is separate from ''X''. The classical unit of Euklid is the elementary unit for counting, entirely independent of measuring. Therefore, the quantity [[count]] is unique with respect to two properties: (''1'') in contrast to all other quantities in the metric system, the count depends on quantization of entities ''X''; and (''2'') in the SI, the '''N'''umber 1 is the '''U'''nit of the '''C'''ount of '''entities''' — NUCE.ntrast to all other quantities in the metric system, the count depends on quantization of entities ''X''; and (''2'') in the SI, the '''N'''umber 1 is the '''U'''nit of the '''C'''ount of '''entities''' — NUCE.)
• Elementary entity  + ([[File:Count-vs-number.png|right|120px|lin … [[File:Count-vs-number.png|right|120px|link=Unit]]</br>An '''elementary entity''' is an [[entity]] of type ''X'', distinguished as a single ''[[unit]]'' of countable objects (''X'' = molecules, cells, organisms, particles, parties, items) or events (''X'' = beats, collisions, emissions, decays, celestial cycles, instances, occurrences, parties). "An elementary entity may be an atom, a molecule, an ion, an electron, any other particle or specified group of particles" ([[Bureau International des Poids et Mesures 2019 The International System of Units (SI) |Bureau International des Poids et Mesures 2019)]]. An elementary entity, therefore, needs to be distinguished from non-countable entities and the general class of entities ''X''. This distinction is emphasized by the term 'elementary' (synonymous with 'elementary entity') with symbol ''U''_''X'' and [[unit |elementary unit]] [x].</br></br>If an object is defined as an assembly of particles (a party of two, a molecule as the assembly of a stoichiometric number of atoms), then the elementary is the assembly but not the assembled particle. A number of defined elementaries ''U''_''X'' is a [[count]], ''N''_''X'' = ''N''·''U''_''X'' [x], where ''N'' is a number, and as such ''N'' is dimensionless, and ''N'' is a ''number'' (stop) and is not 'a number of ..'. Elementaries are added as items to a count. The elementary ''U''_''X'' has the [[dimension]] U of the [[count]] ''N''_''X''. The elementary ''U''_''X'' has the same unit [x] as the count ''N''_''X'', or more accurately it gives the count the defining 'counting-unit', which is the 'elementary unit' [x]. From the definition of count as the number (''N'') of elementaries (''U'') of entity type ''X'', it follows that count divided by elementary is a pure number, ''N'' = ''N''_''X''·''U''_''X''^-1. The unit x of a count can neither be the entity ''X'' nor a number. The elementary of type ''X'' defines the identity ''X'' of the elementary ''U''_''X'' with the unit 'elementary unit' with symbol [x]. Since a count ''N''_''X'' is the number of elementary entities, the elementary ''U''_''X'' is not a count (''U''_''X'' is not identical with ''N''·''U''_''X'').''N''_''X'' is the number of elementary entities, the elementary ''U''_''X'' is not a count (''U''_''X'' is not identical with ''N''·''U''_''X'').)
• Count  + ([[File:Count-vs-number.png|right|120px|lin … [[File:Count-vs-number.png|right|120px|link=Number]]</br>'''Count''' ''N''_''X'' is the [[number]] ''N'' of elementary entities of [[entity]]-type ''X''. The single [[elementary entity]] ''U''_''X'' is a countable object or event. ''N''_''X'' is the number of objects of type ''X'', whereas the term 'entity' and symbol ''X'' are frequently used and understood in dual-message code indicating both (''1'') the entity-type ''X'' and (''2'') a count of ''N''_''X'' = 1 x for a single elementary entity ''U''_''X''. 'Count' is synonymous with 'number of entities' (number of particles such as molecules, or objects such as cells). Count is one of the most fundamental quantities in all areas of physics to biology, sociology, economy and philosophy, including all perspectives of the statics of countable objects to the dynamics of countable events. The term 'number of entities' can be used in short for 'number of elementary entities', since only elementary entities can be counted, and as long as it is clear from the context, that it is not the number of different entity types that are the object of the count.rom the context, that it is not the number of different entity types that are the object of the count.)
• Elementary unit  + ([[File:Count-vs-number.png|right|120px|lin … [[File:Count-vs-number.png|right|120px|link=Elementary entity]]The '''elementary unit''' [x] is the unit of a [[count]] ''N''_''X'' [x]. The [[International System of Units]] defines the unit of a count as 1. Then the '''N'''umber 1 is the '''U'''nit of the '''C'''ount of '''E'''ntities — NUCE. This causes a number of formal inconsistencies which are resolved by introducing the elementary unit [x] as the abstracted unit of Euclid’s unit, which is an [[elementary entity]] ''U''_''X'' [x], and as the unit of Euclid’s number, which is a count ''N''_''X'' [x].it of Euclid’s number, which is a count ''N''_''X'' [x].)
• DORA  + ([[File:Dorabadge5.png|150px|right]] The Declaration on Research Assessment '''DORA''' recognizes the need to improve the ways in which researchers and the outputs of scholarly research are evaluated.)
• Level flow  + ([[File:E.jpg |link=ET capacity]] '''Level … [[File:E.jpg |link=ET capacity]] '''Level flow''' is a [[steady state]] of a system with an input process coupled to an output process (coupled system), in which the output force is zero. ''Clearly, energy must be expended to maintain level flow, even though output is zero'' (Caplan and Essig 1983; referring to zero output force, while output flow may be maximum). force, while output flow may be maximum).)