Wikstroem 1977 Nature: Difference between revisions
No edit summary |
Bader Helga (talk | contribs) No edit summary |
||
| Line 1: | Line 1: | ||
{{Publication | {{Publication | ||
|title=Wikstroem MKF (1977) Proton pump coupled to cytochrome ''c'' oxidase in mitochondria. Nature 266: 271- | |title=Wikstroem MKF (1977) Proton pump coupled to cytochrome ''c'' oxidase in mitochondria. Nature 266:271-3. | ||
|info=[http://www.ncbi.nlm.nih.gov/pubmed/15223 PMID: 15223] | |info=[http://www.ncbi.nlm.nih.gov/pubmed/15223 PMID: 15223] | ||
|authors=Wikstroem MKF | |authors=Wikstroem MKF | ||
| Line 10: | Line 10: | ||
{{Labeling | {{Labeling | ||
|area=Respiration | |area=Respiration | ||
|enzymes=Complex IV; | |enzymes=Complex IV;cytochrome c oxidase | ||
|topics=Coupling efficiency;uncoupling, Cyt c, Ion;substrate transport | |topics=Coupling efficiency;uncoupling, Cyt c, Ion;substrate transport | ||
|couplingstates=OXPHOS | |couplingstates=OXPHOS | ||
Revision as of 15:46, 19 February 2015
| Wikstroem MKF (1977) Proton pump coupled to cytochrome c oxidase in mitochondria. Nature 266:271-3. |
Wikstroem MKF (1977) Nature
Abstract: Cytochrome c oxidase is an important enzyme of aerobic metabolism, catalysing electron transport between cytochrome c and molecular oxygen. Apart from this essential redox reaction the enzyme must be involved in conservation of the released redox energy for utilisation in ATP synthesis at the socalled third site of oxidative phosphorylation. I report here that the redox activity of mitochondrial cytochrome c oxidase is coupled to the translocation of hydrogen ions across the inner mitochondrial membrane. This finding may be a clue to the role of cytochrome oxidase in energy conservation. • Keywords: Cytochrome c oxidase, proton pump, inner mitochondrial membrane
Labels: MiParea: Respiration
Enzyme: Complex IV;cytochrome c oxidase Regulation: Coupling efficiency;uncoupling, Cyt c, Ion;substrate transport Coupling state: OXPHOS
Made history
