Mitochondria: Difference between revisions
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|description='''Mitochondria''' (Greek ''mitos'': thread; ''chondros'': granule) are small structures within cells, which function in cell respiration as powerhouses or batteries. Mitochondria belong to the '''[[bioblasts]]''' of Richard Altmann. Abbreviation: mt, as generally used in mtDNA. Singular: mitochondrion (bioblast); plural: mitochondria (bioblasts). | |description='''Mitochondria''' (Greek ''mitos'': thread; ''chondros'': granule) are small structures within cells, which function in cell respiration as powerhouses or batteries. Mitochondria belong to the '''[[bioblasts]]''' of Richard Altmann. Abbreviation: mt, as generally used in mtDNA. Singular: mitochondrion (bioblast); plural: mitochondria (bioblasts). | ||
|info=Gnaiger | |info=:::: Gnaiger Erich et al ― MitoEAGLE Task Group (2020) Mitochondrial physiology. Bioenerg Commun 2020.1. doi:10.26124/bec:2020-0001.v1. - [[BEC 2020.1 doi10.26124bec2020-0001.v1 |»BEC 2020.1«]] | ||
}} | }} | ||
== Mitochondria are the electric engines in our cells - and research with the Oroboros O2k == | |||
== Mitochondria are the electric engines in our cells == | |||
:::: Mitochondria burn the calories of food and convert them into useful work. How fast do our mitochondrial engines run? With the world-wide successful Oroboros O2k instrument, scientists measure oxygen consumption or cell respiration. With oxygen sensors the O2k addresses the question of rate: how fast does the engine run? | :::: Mitochondria burn the calories of food and convert them into useful work. How fast do our mitochondrial engines run? With the world-wide successful [[Oroboros O2k]] instrument, scientists measure oxygen consumption or cell respiration. With oxygen sensors the O2k addresses the question of rate: how fast does the engine run? | ||
:::: The [[NextGen-O2k]] combines measurement of | :::: The [[NextGen-O2k]] combines measurement of O<sub>2</sub> flux (how fast?) with recording of the redox state of Coenzyme Q, which is centre-place at the [[Q-junction]] of mitochondrial pathways in core energy metabolism. An integrated new Q-sensor provides information on the state of the engine: how hot does it get (actually: how reduced or oxidized does it get). Our mitochondrial engines may run fast, but they may burn out if they get too hot. The new Q-sensor thus adds diagnostic core information on pathologies, which will make the NextGen-O2k the leading technology for mitochondrial research and medicine. This revolutionary all-in-one device is the next step to conquer mitochondrial disease. | ||
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Continue the discussion: [[Talk:Mitochondria]] | Continue the discussion: [[Talk:Mitochondria]] | ||
== References == | |||
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Latest revision as of 17:03, 26 May 2020
- high-resolution terminology - matching measurements at high-resolution
Mitochondria
Description
Mitochondria (Greek mitos: thread; chondros: granule) are small structures within cells, which function in cell respiration as powerhouses or batteries. Mitochondria belong to the bioblasts of Richard Altmann. Abbreviation: mt, as generally used in mtDNA. Singular: mitochondrion (bioblast); plural: mitochondria (bioblasts).
Abbreviation: mt
Reference:
- Gnaiger Erich et al ― MitoEAGLE Task Group (2020) Mitochondrial physiology. Bioenerg Commun 2020.1. doi:10.26124/bec:2020-0001.v1. - »BEC 2020.1«
Mitochondria are the electric engines in our cells - and research with the Oroboros O2k
- Mitochondria burn the calories of food and convert them into useful work. How fast do our mitochondrial engines run? With the world-wide successful Oroboros O2k instrument, scientists measure oxygen consumption or cell respiration. With oxygen sensors the O2k addresses the question of rate: how fast does the engine run?
- The NextGen-O2k combines measurement of O2 flux (how fast?) with recording of the redox state of Coenzyme Q, which is centre-place at the Q-junction of mitochondrial pathways in core energy metabolism. An integrated new Q-sensor provides information on the state of the engine: how hot does it get (actually: how reduced or oxidized does it get). Our mitochondrial engines may run fast, but they may burn out if they get too hot. The new Q-sensor thus adds diagnostic core information on pathologies, which will make the NextGen-O2k the leading technology for mitochondrial research and medicine. This revolutionary all-in-one device is the next step to conquer mitochondrial disease.
Mitochondrial disease
- Among 4,000 people, 1 is a patient affected by mitochondrial disease - a deadly pathology, progressive, little understood, and therefore largely without hope for a cure. Beyond mitochondrial diseases, mitochondria are recognized as key players in disease related to a sedentary lifstyle and aging, such as Alzheimer's. The Oroboros O2k technology supports research to make a difference.
mt
- The field of mitochondrial physiology might gain by aiming at a consensus on the abbreviation for 'mitochondrial'. It is not best practice to use in the same context 'mt' for mtDNA, but 'mi' for miCK (mitochondrial creatine kinase; compare miRNA), and 'm' for mPTP (mitochondrial permeability transition pore). The use of 'mt' in mtDNA seems to be most common and robust, hence the suggestion to use mtCK, etc. --Gnaiger Erich 07:01, 24 April 2012 (CEST)
Continue the discussion: Talk:Mitochondria
References
| Bioblast link | Reference | Year |
|---|---|---|
| BEC 2020.1 doi10.26124bec2020-0001.v1 | Gnaiger E et al ― MitoEAGLE Task Group (2020) Mitochondrial physiology. Bioenerg Commun 2020.1. https://doi.org/10.26124/bec:2020-0001.v1 | 2020 |
MitoPedia concepts:
MiP concept
