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Difference between revisions of "Triethyltin bromide"

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{{MitoPedia
{{MitoPedia
|abbr=TET
|abbr=TET
|description=Triethyltin bromide (TET) is a lipophilic [1] inhibitor of the mitochondrial [[ATP synthase]] [2] which is used to induce [[LEAK state]] in [[intact cells]] of ''Saccharomyces cerevisiae''.
|description=Triethyltin bromide (TET) is a lipophilic [1] inhibitor of the mitochondrial [[ATP synthase]] [2] which is used to induce [[LEAK state]] in [[living cells]] of ''Saccharomyces cerevisiae''.


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{{MitoPedia concepts}}
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{{MitoPedia methods}}
{{MitoPedia O2k and high-resolution respirometry}}
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ย  Contributed by [[Kandolf G]] 2016-02-08
ย  Contributed by [[Kandolf G]] 2016-02-08


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#Cain K, Griffiths DE (1977) Studies of energy-linked reactions. Localization of the site of action of trialkyltin in yeast mitochondria. Biochem J 162:575-80. [http://www.biochemj.org/content/162/3/575.full-text.pdf Open Access]]
#Cain K, Griffiths DE (1977) Studies of energy-linked reactions. Localization of the site of action of trialkyltin in yeast mitochondria. Biochem J 162:575-80. [http://www.biochemj.org/content/162/3/575.full-text.pdf Open Access]]
#Also see: Sundaram V, Petkova MI, Pujol-Carrion N, Boada J, de la Torre-Ruiz MA (2015) Tor1, Sch9 and PKA downregulation in quiescence rely on Mtl1 to preserve mitochondrial integrity and cell survival. Mol Microbiol 97:93-109. [[Sundaram 2015 Mol Microbiol|Bioblast Link]]
#Also see: Sundaram V, Petkova MI, Pujol-Carrion N, Boada J, de la Torre-Ruiz MA (2015) Tor1, Sch9 and PKA downregulation in quiescence rely on Mtl1 to preserve mitochondrial integrity and cell survival. Mol Microbiol 97:93-109. [[Sundaram 2015 Mol Microbiol|Bioblast Link]]
{{MitoPedia concepts}}
{{MitoPedia methods}}
{{MitoPedia O2k and high-resolution respirometry}}
{{MitoPedia topics
|mitopedia topic=Inhibitor
}}

Latest revision as of 10:37, 11 September 2020


high-resolution terminology - matching measurements at high-resolution


Triethyltin bromide

Description

Triethyltin bromide (TET) is a lipophilic [1] inhibitor of the mitochondrial ATP synthase [2] which is used to induce LEAK state in living cells of Saccharomyces cerevisiae.

Abbreviation: TET


Contributed by Kandolf G 2016-02-08


Chemical formula: (C2H5)3SnBr

Synonym: Bromotriethylstannane

Sigma-Aldrich

References

  1. Aguilaniu H, Gustafsson L, Rigoulet M, Nystrรถm T (2001) Protein oxidation in G0 cells of Saccharomyces cerevisiae depends on the state rather than rate of respiration and is enhanced in pos9 but not yap1 mutants. J Biol Chem 276:35396-404. Bioblast Link
  2. Cain K, Griffiths DE (1977) Studies of energy-linked reactions. Localization of the site of action of trialkyltin in yeast mitochondria. Biochem J 162:575-80. Open Access]
  3. Also see: Sundaram V, Petkova MI, Pujol-Carrion N, Boada J, de la Torre-Ruiz MA (2015) Tor1, Sch9 and PKA downregulation in quiescence rely on Mtl1 to preserve mitochondrial integrity and cell survival. Mol Microbiol 97:93-109. Bioblast Link






MitoPedia topics: Inhibitor