Difference between revisions of "Triethyltin bromide"

Revision as of 17:52, 8 February 2016

high-resolution terminology - matching measurements at high-resolution

Triethyltin bromide

Description

Triethyltin bromide (TET) is a lipophilic [1] inhibitor of the mitochondrial ATP synthase [2] which is used to induce LEAK state in intact cells of Saccharomyces cerevisiae.

Abbreviation: TET

MitoPedia topics: Inhibitor

Contributed by Kandolf G 2016-02-08

Chemical formula: (C₂H₅)₃SnBr

Synonym: Bromotriethylstannane

Sigma-Aldrich

References

Aguilaniu H, Gustafsson L, Rigoulet M, Nyström T (2001) Protein oxidation in G0 cells of Saccharomyces cerevisiae depends on the state rather than rate of respiration and is enhanced in pos9 but not yap1 mutants. J Biol Chem 276:35396-404. Bioblast Link
Cain K, Griffiths DE (1977) Studies of energy-linked reactions. Localization of the site of action of trialkyltin in yeast mitochondria. Biochem J 162:575-80. Open Access]
Also see: Sundaram V, Petkova MI, Pujol-Carrion N, Boada J, de la Torre-Ruiz MA (2015) Tor1, Sch9 and PKA downregulation in quiescence rely on Mtl1 to preserve mitochondrial integrity and cell survival. Mol Microbiol 97:93-109. Bioblast Link

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 {{MitoPedia
 |abbr=TET
-|description=Triethyltin bromide (TET) is a lipophilic [1] inhibitor of the mitochondrial ATPase [2] which is used to induce [[LEAK state]] in [[intact cells]] of ''Saccharomyces cerevisiae''.
+|description=Triethyltin bromide (TET) is a lipophilic [1] inhibitor of the mitochondrial [[ATP synthase]] [2] which is used to induce [[LEAK state]] in [[intact cells]] of ''Saccharomyces cerevisiae''.
-Linear Formula: (C<sub>2</sub>H<sub>5</sub>)<sub>3</sub>SnBr
+}}
+{{MitoPedia concepts}}
+{{MitoPedia methods}}
+{{MitoPedia O2k and high-resolution respirometry}}
+{{MitoPedia topics
+|mitopedia topic=Inhibitor
+}}
+ Contributed by [[Kandolf G]] 2016-02-08
+Chemical formula: (C<sub>2</sub>H<sub>5</sub>)<sub>3</sub>SnBr
 Synonym: Bromotriethylstannane
 [http://www.sigmaaldrich.com/catalog/product/aldrich/288047?lang=de&region=AT&gclid=CNS0idr158oCFUKeGwodeKoNjg Sigma-Aldrich]
-}}
-{{MitoPedia concepts
-|mitopedia concept=Respiratory state
-}}
-{{MitoPedia methods
-|mitopedia method=Respirometry
-}}
-{{MitoPedia O2k and high-resolution respirometry}}
-{{MitoPedia topics
-|mitopedia topic=Enzyme, Inhibitor
-}}
-Contributed by [[Kandolf G]] 2016-02-08
 === References ===