Template:Next oroboros ecosystem agenda

2023 Week 7

Feb- 13 Mo - International Epilepsy Day

"NAC [N-acetylcysteine] modulates neuronal excitability and the appearance or propagation of seizures through its antioxidant capacity and ability to reduce glycolytic/lactic metabolism in WAR [Wistar Audiogenic Rat – a genetic model of epilepsy]"

Dechandt CRP, Ferrari GD, Dos Santos JR, de Oliveira JAC, da Silva-Jr RMP, Cunha AOS, Garcia-Cairasco N, Alberici LC (2019) Energy metabolism and redox state in brains of wistar audiogenic rats, a genetic model of epilepsy. Front Neurol 10:1007. »Bioblast link«

from the O2k-Network »BR Ribeirao Preto Alberici LC

Feb- 14 Tu

Oroboros O2k-Workshop on high-resolution respirometry (HRR) IOC 157 Los Angeles US Feb 14-16

Feb- 15 We - International Childhood Cancer Day

Feb- 16 Th

Do you observe simultaneous fluctuations in the O₂ slope neg. and the Peltier power?

This can indicate fluctuations in the room temperature or electrical supply. Controlling the temperature or changing the electrical supply may resolve this problem.
- »Troubleshooting«
- communicated by »Cecatto Cristiane« and »Schmitt Sabine«

Feb- 17 Fr

Feb- 18 Sa

»BPS2023 San Diego US« Feb 18-22

Feb- 19 Su

09:30 (GMT-9) Erich Gnaiger presenting at BPS2023 San Diego US - Mitochondrial bioenergetics – a quantitative analytical and diagnostic approach

13:45 (GMT-9) Sabine Schmitt poster session at at BPS2023 San Diego US - Contribution of fatty acid oxidation to respiratory control in brain mitochondria

2023 Week 8

Feb- 20 Mo

»BPS2023 San Diego US« Feb 18-22

13:45 (GMT-9) Erich Gnaiger poster session at at BPS2023 San Diego US - Respirometric substrate-uncoupler-inhibitor titration protocols for carbohydrate and fatty acid metabolism: from heart to brain mitochondria

Abstract submission deadline for »ATSPB 2023 Hall in Tirol AT«

Feb- 21 Tu

Feb- 22 We - World Encephalitis Day

Feb- 23 Th

Add catalase when measuring Complex IV (CIV) activity in permeabilized fibers (pfi)

Pfi have a high content of iron-containing proteins, which accelerate the autoxidation of tetramethyl-p-phenylenediamine (TMPD) in the CIV assay. Catalase prevents the accumulation of H₂O₂ generated by this autoxidation.
- »Chemical Background« and »Complex IV«
- communicated by »Cecatto Cristiane« and »Schmitt Sabine«

Feb- 24 Fr

2023 Week 9

Feb- 27 Mo

158^th Oroboros O2k-Coaching Days - Basic Feb 27 - Mar 1

Feb- 28 Tu - Rare Disease Day

158^th Oroboros O2k-Coaching Days - Basic Feb 27 - Mar 1

Balbaisi and Stiban review the current knowledge on Barth Syndrome, a rare disease affecting the production of cardiolipin, the only phospholipid specific to mitochondria.

Balbaisi A, Stiban J (2022) Barth syndrome: a genetic ailment with a lipid component and bioenergetic ramifications. Bioenerg Commun 2022.5. https://doi.org/10.26124/bec:2022-0005

Abstract deadline for »EUROMIT2023 Bologna IT«

Mar- 01 We

158^th Oroboros O2k-Coaching Days - Basic Feb 27 - Mar 1

Mar- 02 Th

Mar- 03 Fr - World Wildlife Day

"[...]adaptive changes in the physiology of specific mitochondrial fractions can help overcome the metabolic challenges of life in the harsh environment at high altitude."

Dawson NJ, Scott GR (2022) Adaptive increases in respiratory capacity and O2 affinity of subsarcolemmal mitochondria from skeletal muscle of high-altitude deer mice. »Bioblast link«

from the O2k-Network »CA Hamilton Scott GR

2023 Week 10

Mar- 06 Mo

Mar- 07 Tu

Mar- 08 We - International Women's Day

Mar- 09 Th

Mar- 10 Fr - World Kidney Day

"...subcapsular administration of MSC-derived EVs [extracellular vesicles secreted by adipose tissue mesenchymal cells] at the moment of reperfusion after ischemia totally recovers the normal ROS formation by mitochondria from renal proximal tubule cells in all functional respiratory states"

Lopes JA, Collino F, Rodrigues-Ferreira C, Sampaio LDS, Costa-Sarmento G, Wendt CHC, Almeida FP, Miranda KR, Kasai-Brunswick TH, Lindoso RS, Vieyra A (2022) Early effects of extracellular vesicles secreted by adipose tissue mesenchymal cells in renal ischemia followed by reperfusion: mechanisms rely on a decrease in mitochondrial anion superoxide production »Bioblast link«

from the O2k-Network »BR Rio de Janeiro Vieyra A

2023 Week 11

Mar- 13 Mo

Mar- 14 Tu

Mar- 15 We

Mar- 16 Th

Mar- 17 Fr

2023 Week 12

Mar- 20 Mo

Mar- 21 Tu

Mar- 22 We

Mar- 23 Th

Mar- 24 Fr - World Tuberculosis Day-

"The molecular structure of the bd oxidase from M. tuberculosis provides the long-sought atomic framework for the design of highly specific drugs to target this respiratory enzyme"

Safarian S, Opel-Reading HK, Wu D, Mehdipour AR, Hards K, Harold LK, Radloff M, Stewart I, Welsch S, Hummer G, Cook GM, Krause KL, Michel H (2021) The cryo-EM structure of the bd oxidase from M. tuberculosis reveals a unique structural framework and enables rational drug design to combat TB. »Bioblast link«

Mar- 25 Sa

Early bird registration deadline for »EUROMIT2023 Bologna IT«

2023 Week 13

Mar- 27 Mo

Mar- 28 Tu

Mar- 29 We

Mar- 30 Th

Mar- 31 Fr

Abstract submission deadline for »MiPschool Obergurgl 2023« & »MiP2023 Obergurgl AT«

2023 Week 14

Apr- 03 Mo

Apr- 04 Tu

Apr- 05 We

Apr- 06 Th

Apr- 07 Fr

2023 Week 15

Apr- 10 Mo

Apr- 11 Tu

Apr- 12 We

Apr- 13 Th

»ATSPB 2023 Hall in Tirol AT« Apr 13-15

Apr- 14 Fr

Early registration deadline for »MiPschool Obergurgl 2023« & »MiP2023 Obergurgl AT«

2023 Week 16

Apr- 17 Mo

Apr- 18 Tu

Apr- 19 We

FAT4BRAIN 159^th O2k-Workshop

Apr- 20 Th

»FAT4BRAIN Symposium Riga LV« April 20-21

»Mitochondrial Dysfunction and Neurodegeneration 2023 Nottingham UK« Apr 20-21

Apr- 21 Fr

2023 Week 17

Apr- 24 Mo

Apr- 25 Tu

Apr- 26 We

Apr- 27 Th

Apr- 28 Fr

2023 Week 18

May- 01 Mo

May- 02 Tu

May- 03 We

May- 04 Th

May- 05 Fr

2023 Week 19

May- 08 Mo

May- 09 Tu

May- 10 We

May- 11 Th

May- 12 Fr

2023 Week 20

May- 15 Mo

May- 16 Tu

May- 17 We

May- 18 Th

May- 19 Fr

2023 Week 21

May- 22 Mo

May- 23 Tu

May- 24 We

May- 25 Th

May- 26 Fr

2023 Week 22

May- 29 Mo

May- 30 Tu

Registration deadline for »EUROMIT2023 Bologna IT«

May- 31 We

Jun- 01 Th

Jun- 02 Fr

2023 Week 23

Jun- 05 Mo

Jun- 06 Tu

Jun- 07 We

»ESCI 2023 Prague CZ« Jun 7-9

Jun- 08 Th

»International GIBB Meeting 2023 Riva del Garda IT« Jun 8-10

Jun- 09 Fr

Jun- 10 Sa

Jun- 11 Su

»EUROMIT2023 Bologna IT« Jun 11-15

2023 Week 24

Jun- 12 Mo

»EUROMIT2023 Bologna IT« Jun 11-15

Jun- 13 Tu

Jun- 14 We

Jun- 15 Th

Jun- 16 Fr

2023 Week 25

Jun- 19 Mo