Difference between revisions of "Template:Next oroboros ecosystem agenda"

Revision as of 13:56, 25 August 2023

2023 Week 35

Aug- 28 Mo

Can I compare data sets recorded with different sensor gain settings?

Oxygen signals obtained after proper calibration are independent of the gain settings, therefore oxygen concentrations (and fluxes) can be compared, as long as the corresponding air and zero calibrations are applied.
- »Gain of the O2 channel«
- communicated by »Baglivo Eleonora« and »Leo Elettra«

Aug- 29 Tu

"Altogether, our results show that chronic hypoxia optimizes the efficiency of mitochondrial ATP synthesis in the retrosplenial cortex of mice. Contrastingly, rats sustain the production of ATP only by increasing mitochondrial content and altering mitochondrial dynamics, suggesting drastic mitochondrial malfunctions."

Arias-Reyes C, Aliaga-Raduán F, Pinto-Aparicio R, Joseph V, Soliz J (2023) Mitochondrial plasticity in the retrosplenial cortex enhances ATP synthesis during acclimatization to hypoxia in mice but not in rats. MitoFit Preprints 2023.6. https://doi.org/10.26124/mitofit:2023-0006

from the O2k-Network »CA Quebec Soliz J«

Aug- 30 We

Aug- 31 Th

"Our study showed that salinity modulates the mitochondrial responses to long-term and acute hypoxia exposure in an euryhaline intertidal bivalve C. gigas."

Steffen JBM, Sokolov EP, Sokolova IM (2023) Combined effects of salinity and intermittent hypoxia on mitochondrial capacity and reactive oxygen species efflux in the Pacific oyster, Crassostrea gigas »Bioblast link«

from the O2k-Network »DE Rostock Sokolova I«

Sep- 01 Fr

2023 Week 36

Sep- 04 Mo

Sep- 05 Tu

Higher concentrations of oligomycin can decrease the ET capacity due to an inhibitory effect

Use a lower oligomycin concentration (5-10 nM) to measure LEAK respiration without impairing ET capacity and test to find the optimum concentration for your specific model.
- »Oligomycin in high-resolution respirometry«, »Doerrier 2018 Methods Mol Biol«
- communicated by »Timon-Gomez Alba« and »Grings Mateus«

Sep- 06 We

Sep- 07 Th

"...enhancing mitochondrial function by either overexpressing parkin or bypassing defective mitochondrial complexes has significant beneficial effects in a fly model of HD [Huntington's disease], rescuing neurodegeneration and enhancing viability and lifespan."

Campesan S, Del Popolo I, Marcou K, Straatman-Iwanowska A, Repici M, Boytcheva KV, Cotton VE, Allcock N, Rosato E, Kyriacou CP, Giorgini F (2023) Bypassing mitochondrial defects rescues Huntington's phenotypes in Drosophila. »Bioblast link«

from the O2k-Network »UK Leicester Giorgini F«

Sep- 08 Fr

2023 Week 37

Sep- 11 Mo

Sep- 12 Tu

Sep- 13 We

Sep- 14 Th

Sep- 15 Fr - World Lymphoma Awareness Day

"Respirometry assays confirmed that OXPHOS^high Richter transformation cells had a 3.5-fold higher oxygen consumption at ROUTINE respiration and fivefold higher electron transfer system capacity compared to chronic lymphocytic leukemia"

Nadeu F, Royo R, Massoni-Badosa R, Playa-Albinyana H, Garcia-Torre B, et al (2022) Detection of early seeding of Richter transformation in chronic lymphocytic leukemia. »Bioblast link«

from the O2k-Network »ES Barcelona Garcia-Roves PM« and »ES Barcelona IDIBAPS Hospital Clinic«

2023 Week 38

Sep- 18 Mo

Sep- 19 Tu

Sep- 20 We

Sep- 21 Th

Sep- 22 Fr

2023 Week 39

Sep- 25 Mo

Sep- 26 Tu

Sep- 27 We

Sep- 28 Th

Sep- 29 Fr

2023 Week 40

Oct- 02 Mo