Template:Coupling-control tables: Difference between revisions
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File:Flux control ratios related to coupling.png |link=Gnaiger_2020_MitoPathways | File:Flux control ratios related to coupling.png |link=Gnaiger_2020_MitoPathways | ||
File:Net, excess, and reserve capacities PREL.png |link=Gnaiger_2020_MitoPathways | File:Net, excess, and reserve capacities PREL.png |link=Gnaiger_2020_MitoPathways | ||
File:Flux control efficiencies related to coupling control ratios.jpg |link=Gnaiger_2020_MitoPathways | (''P-L'')/''P'' is the OXPHOS ''P-L'' | File:Flux control efficiencies related to coupling control ratios.jpg |link=Gnaiger_2020_MitoPathways | (''P-L'')/''P'' is the OXPHOS ''P-L'' control efficiency. The biochemical coupling efficiency is independent of kinetic control by the phosphorylation system when expressed as the ''E-L'' coupling efficiency, (''E-L'')/''E''. (''E-P'')/''E'' is the kinetic ''E-P'' control efficiency. | ||
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Revision as of 10:32, 12 November 2020
The Blue Book 2020
OXPHOS-, ROUTINE-, ET-, and LEAK states; respiratory capacities (P, R, E, L) corrected for residual oxygen consumption Rox.
4-compartmental OXPHOS model. (1) ET capacity E of the noncoupled electron transfer system ETS. OXPHOS capacity P is partitioned into (2) the dissipative LEAK component L, and (3) ADP-stimulated P-L net OXPHOS capacity. (4) If P-L is kinetically limited by a low capacity of the phosphorylation system to utilize the protonmotive force pmF, then the apparent E-P excess capacity is available to drive coupled processes other than phosphorylation P» (ADP to ATP) without competing with P».
(P-L)/P is the OXPHOS P-L control efficiency. The biochemical coupling efficiency is independent of kinetic control by the phosphorylation system when expressed as the E-L coupling efficiency, (E-L)/E. (E-P)/E is the kinetic E-P control efficiency.
