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| {{Template:OROBOROS header page name}}
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| <big><big>'''Oroboros Robotics - O2k-Titration Platform'''</big></big>
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| [[File:FFG-logo.png|right|200px|FFG]]
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| __TOC__
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| == Oroboros Robotics ==
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| ::::* Cooperative project
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| ::::* '''Duration''': 18-24 months
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| ::::* '''Start''': tbc
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| == About Oroboros Robotics ==
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| ::::* '''Oroboros Robotics''' - maintain high output at increased throughput.
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| :::::: We aim at developing an O2k-Titration Platform for the [[O2k]] instrument. This titration solution will enable to automatically carry out multiple titrations with different chemicals within a single experimental assay. The application of complex [[SUIT]] protocols and handling multiple O2k-Instruments simultaneously will become easier with further improved reproducibility.
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| :::::: The [[TIP2k-Module |Titration-Injection microPump (TIP2k)]] for two-channel operation with automatic control by DatLab will remain the O2k-module of choice for oxystat and pH-stat titrations. However, the TIP2k is limited to titrations of single compounds simultaneously into both O2k-chambers. These limitations will be overcome by the O2k-Titration Robot.
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| === Aims ===
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| ::::* Instrumental development of automated O2k-Titration Robot for application in SUIT protocols.
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| ::::* Integration with the DatLab software.
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| ::::* Market launch of the O2k-Titration Robot.
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| === References ===
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| ::::* Doerrier C, Garcia-Souza LF, Krumschnabel G, Wohlfarter Y, Mészáros AT, Gnaiger E (2018) High-Resolution FluoRespirometry and OXPHOS protocols for human cells, permeabilized fibers from small biopsies of muscle, and isolated mitochondria. https://doi.org/10.1007/978-1-4939-7831-1_3
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| ::::* Gradl L, Gradl P, Gnaiger E (2021) Titration-Injection microPump TIP2k manual. Mitochondr Physiol Network 12.10(09):1-20. - [[MiPNet12.10 TIP2k-manual |»Bioblast link«]]
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| ::::* Harrison DK, Fasching M, Fontana-Ayoub M, Gnaiger E (2015) Cytochrome redox states and respiratory control in mouse and beef heart mitochondria at steady-state levels of hypoxia. https://doi.org/10.1152/japplphysiol.00146.2015
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| == Coordinators ==
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| ::::* [[Gnaiger C| '''Carolina Gnaiger''']] - Oroboros project management
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| ::::* Bernhard Sagmeister - [https://acmit.at/ ACMIT GmbH]
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| == Network ==
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| === Partners ===
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| [[File:Acmit Logo.jpg|right|200px|ACMIT]]
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| :::: '''ACMIT GmbH''' - Austrian Center for Medical Innovation and Technology - [https://acmit.at/ www.acmit.at]
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| ::::* '''DI Bernhard Nußbaumer, MAS, EMBA''' - Chief Business Development Officer
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| ::::* ACMIT is a COMET Center (K1) funded within COMET – Competence Centers for Excellent Technologies – by BMK, BMDW as well as the co-financing federal provinces Lower Austria and Tyrol. The COMET programme is managed by FFG.
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| ::::: ACMIT is an EN ISO 13485 certified research and development center in the field of medical technology and offers:
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| :::::* R&D services all along the process chain from idea to clinical use of a medical device.
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| :::::* Incubator services for medical technology startups.
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| :::::* Contract Manufacturing (small series) of medical devices.
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| :::: '''Oroboros Instruments GmbH''' - [https://www.oroboros.at/ www.oroboros.at]
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| ::::* [[Gnaiger E| '''Erich Gnaiger, Ph.D.''']] - PI
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| ::::* [[Schmitt Sabine| '''Sabine Schmitt, Ph.D''']]
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| ::::* [[Gnaiger C| '''Carolina Gnaiger''']] - Oroboros project management
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| === Third parties ===
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| ::::* WGT-Elektronik GmbH & Co KG, [[Walter-Vracevic Michael]]
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| ::::* inncode technologies gmbh, [[Haider Markus]]
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| == Oroboros Robotics Events ==
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| {{#ask:[[Category:Publications]] [[Additional label::Oroboros Diagnostics events]]
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| |?Was published in year=When
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| |?Has title=Where
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| |format=broadtable
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| |limit=5000
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| |offset=0
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| |sort=Was published in year
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| |order=descending
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| }}
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| == Oroboros Robotics Publications ==
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| {{#ask:[[Additional label::Oroboros Robotics]]
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| | mainlabel=Link
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| |?Has title=Reference
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| |?Has info=View
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| |?Was published in year=Year
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| |format=broadtable
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| |limit=5000
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| |offset=0
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| |sort=Has title
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| |order=descending
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| }}
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| == Links ==
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| '''News and articles'''
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| == Support ==
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| ::::* This project receives support from ACMIT GmbH: [https://acmit.at/company-about/#Comet-CompetenceCenter COMET - Competence Center].
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| ::::: The COMET Center (K1) ACMIT is funded within COMET – Competence Centers for Excellent Technologies – by BMK, BMDW as well as the co-financing federal provinces Lower Austria and Tyrol. The COMET programme is managed by the Austrian Research Promotion Funding Agency FFG [https://www.ffg.at/comet (www.ffg.at/comet)]. [[File:FFG-logo.png|100px]]
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