Description
A submitochondrial particle is a compartmentalized membranous product of the mitochondria by treatment of mitochondria with membrane-dispersing agents such as digitonin at high concentration or by sonic irradiation.
Abbreviation: SmtP
Reference: Droese 2009 Biochim Biophys Acta
The submitochondrial particles (SmtP) consist of membrane fragments which evidently retained most of the enzymatic machinery required in electron transfer and oxidative phosphorylation. Such membrane fragments are continuous closed vesicles formed by resealing of the edges of mt-membrane fragments after disruption of the mitochondrial structure. SmtP are used to isolate the inner-membrane-bound ETS (mETS) from the upstream modules of the electron transfer system (ETS).