Difference between revisions of "Submitochondrial particles"
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Revision as of 05:14, 17 August 2016
Description
Submitochondrial particles (smtp) consist of membrane fragments which retain most of the enzymatic machinery required in electron transfer and oxidative phosphorylation. Such membrane fragments are continuous closed vesicles formed by resealing of mt-membrane fragments after disruption of the mitochondrial structure. smtp are used to isolate the inner-membrane-bound ETS (mETS) from the upstream modules of the electron transfer system (ETS) which are located in the mt-matrix and outer mt-membrane (transporters). smtp are obtained by treatment of mitochondria with membrane-dispersing agents such as digitonin at high concentration or by sonic irradiation.
Abbreviation: smtp
Reference: Droese 2009 Biochim Biophys Acta
MitoPedia topics:
Sample preparation
Abbreviations
- It is suggested to replace other frequently used abbreviations for submitochondrial particle (such as SMP) by smtp, with reference to mt as the common abbreviation for mitochondria.