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A list of all pages that have property "Description" with value "The '''mitochondrial free radical theory of aging''' goes back to Harman (1956) and ranks among the most popular theories of aging. It is based on postulates which are not unequivocally supported by observation (Bratic, Larsson 2013): (i) Mitochondrial ROS production increases with age caused by progressive mitochondrial dysfunction; (ii) antioxidat capacity declines with age; (iii) mutations of somatic mtDNA accumulate during aging; (iv) a vicious cycle occurs of increased ROS production caused by mtDNA mutations and degenerated mt-function, and due to ROS-induced ROS production.". Since there have been only a few results, also nearby values are displayed.

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Mitochondrial free radical theory of aging + (The '''mitochondrial free radical theory o … The '''mitochondrial free radical theory of aging''' goes back to Harman (1956) and ranks among the most popular theories of aging. It is based on postulates which are not unequivocally supported by observation (Bratic, Larsson 2013):</br>(i) Mitochondrial ROS production increases with age caused by progressive mitochondrial dysfunction;</br>(ii) antioxidat capacity declines with age;</br>(iii) mutations of somatic mtDNA accumulate during aging;</br>(iv) a vicious cycle occurs of increased ROS production caused by mtDNA mutations and degenerated mt-function, and due to ROS-induced ROS production.on, and due to ROS-induced ROS production.)

Mitochondrial free radical theory of aging +