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- P/E control ratio + ([[Image:P over E.jpg|50 px|OXPHOS-control โฆ [[Image:P over E.jpg|50 px|OXPHOS-control ratio]] The '''''P/E'' control ratio''' ([[OXPHOS]]/[[Electron transfer pathway|ET pathway]]; phosphorylation system control ratio) is an expression of the limitation of OXPHOS capacity by the [[phosphorylation system]]. The relative limitation of OXPHOS capacity by the capacity of the phosphorylation system is better expressed by the [[E-P control efficiency |''E-P'' control efficiency]], ''j<sub>E-P</sub>'' = 1-''P/E''. The ''P/E'' control ratio increases with increasing capacity of the phosphorylation system up to a maximum of 1.0 when it matches or is in excess of ET capacity. ''P/E'' also increases with uncoupling. ''P/E'' increases from the lower boundary set by ''[[L/E]]'' (zero capacity of the phosphorylation system), to the upper limit of 1.0, when there is no limitation of ''P'' by the phosphorylation system or the proton backpressure (capacity of the phosphorylation system fully matches the [[ET capacity]]; or if the system is fully [[uncoupled]]). It is important to separate the kinetic effect of ADP limitation from limitation by enzymatic capacity at saturating ADP concentration.</br>ยป [[#P.2FE_from_mouse_to_man |'''MiPNet article''']][#P.2FE_from_mouse_to_man |'''MiPNet article''']])