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A list of all pages that have property "Description" with value "'''Phosphoenolpyruvate carboxykinase''' (PEPCK) catalyzes the anabolic reaction of [[oxaloacetate]] (Oxa) to [[phosphoenolpyruvate]] at the expense of GTP. PEPCK is a cytoplasmatic enzyme involved in gluconeogenesis in mouse and rat liver, but 'is found in the mitochondria in the rabbit and chicken, and in both cytoplasm and mitochondria in the guinea pig' ([[Lehninger 1970 Worth Publishers |Lehninger 1970]]). In many anoxia-resistant animals, PEPCK plays an important catabolic role under severe hypoxia and anoxia at the PEPCK branchpoint ([[Hochachka 2002 Oxford Univ Press |Hochachka, Somero 2002)]], feeding malate into the reversed TCA cycle: malate is dismutated to pyruvate catalyzed by [[malic enzyme]] in the oxidative direction, and to fumarate in the reductive direction, leading to formation of succinate and ATP under anoxia ([[Gnaiger 1977 Invertebrate anoxibiosis |Gnaiger 1977]]).". Since there have been only a few results, also nearby values are displayed.

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    • Phosphoenolpyruvate carboxykinase  + ('''Phosphoenolpyruvate carboxykinase''' (P'''Phosphoenolpyruvate carboxykinase''' (PEPCK) catalyzes the anabolic reaction of [[oxaloacetate]] (Oxa) to [[phosphoenolpyruvate]] at the expense of GTP. PEPCK is a cytoplasmatic enzyme involved in gluconeogenesis in mouse and rat liver, but 'is found in the mitochondria in the rabbit and chicken, and in both cytoplasm and mitochondria in the guinea pig' ([[Lehninger 1970 Worth Publishers |Lehninger 1970]]). In many anoxia-resistant animals, PEPCK plays an important catabolic role under severe hypoxia and anoxia at the PEPCK branchpoint ([[Hochachka 2002 Oxford Univ Press |Hochachka, Somero 2002)]], feeding malate into the reversed TCA cycle: malate is dismutated to pyruvate catalyzed by [[malic enzyme]] in the oxidative direction, and to fumarate in the reductive direction, leading to formation of succinate and ATP under anoxia ([[Gnaiger 1977 Invertebrate anoxibiosis |Gnaiger 1977]]).[[Gnaiger 1977 Invertebrate anoxibiosis |Gnaiger 1977]]).)