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A list of all pages that have property "Description" with value "'''Fatty acids''' are carboxylic acids with a carbon aliphatic chain. The fatty acids can be spanided by the length of this chain, being considered as short-chain (1–6 carbons), medium-chain (7–12 carbons) and long-chain and very long-chain fatty acids (>12 carbons). Long-chain fatty acids must be bound to [[Carnitine|carnitine]] to enter the mitochondrial matrix, in a reaction that can be catalysed by [[Carnitine acyltransferase|carnitine acyltransferase]]. For this reason, long-chain fatty acids, such as [[Palmitate|palmitate]] (16 carbons) is frequently supplied to mt-preparations in the activated form of [[Palmitoylcarnitine|palmitoylcarnitine]]. Fatty acids with shorter chains, as [[Octanoate|octanoate]] (8 carbons) may enter the mitochondrial matrix, however, in HRR they are more frequently supplied also in the activated form, such as [[Octanoylcarnitine|octanoylcarnitine]]. Once in the mitochondrial matrix, the [[Fatty acid oxidation|fatty acid oxidation]] (FAO) occurs, generating acetyl-CoA, NADH and FADH2. In the [[Fatty acid oxidation pathway control state|fatty acid oxidation pathway control state]] electrons are fed into the [[F-junction]] involving the [[electron transferring flavoprotein]] (CETF). FAO cannot proceed without a substrate combination of fatty acids & malate, and inhibition of CI blocks FAO. Low concentration of [[malate]], typically 0.1 mM, does not saturate the [[N-pathway]]; but saturates the [[Fatty acid oxidation pathway control state |F-pathway]].". Since there have been only a few results, also nearby values are displayed.

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    • Fatty acid  + ('''Fatty acids''' are carboxylic acids wit'''Fatty acids''' are carboxylic acids with a carbon aliphatic chain. The fatty acids can be divided by the length of this chain, being considered as short-chain (1–6 carbons), medium-chain (7–12 carbons) and long-chain and very long-chain fatty acids (>12 carbons).</br>Long-chain fatty acids must be bound to [[Carnitine|carnitine]] to enter the mitochondrial matrix, in a reaction that can be catalysed by [[Carnitine acyltransferase|carnitine acyltransferase]]. For this reason, long-chain fatty acids, such as [[Palmitate|palmitate]] (16 carbons) is frequently supplied to mt-preparations in the activated form of [[Palmitoylcarnitine|palmitoylcarnitine]].</br>Fatty acids with shorter chains, as [[Octanoate|octanoate]] (8 carbons) may enter the mitochondrial matrix, however, in HRR they are more frequently supplied also in the activated form, such as [[Octanoylcarnitine|octanoylcarnitine]].</br></br>Once in the mitochondrial matrix, the [[Fatty acid oxidation|fatty acid oxidation]] (FAO) occurs, generating acetyl-CoA, NADH and FADH2. In the [[Fatty acid oxidation pathway control state|fatty acid oxidation pathway control state]] electrons are fed into the [[F-junction]] involving the [[electron transferring flavoprotein]] (CETF). FAO cannot proceed without a substrate combination of fatty acids & malate, and inhibition of CI blocks FAO. Low concentration of [[malate]], typically 0.1 mM, does not saturate the [[N-pathway]]; but saturates the [[Fatty acid oxidation pathway control state |F-pathway]].tty acid oxidation pathway control state |F-pathway]].)