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|title=McKeehan WL (1982) Glycolysis, glutaminolysis and cell proliferation. Cell Biol Int Rep 6:635-50. ...ost abundant single amino acid in plasma, tissues and cell culture media. 'Glutaminolysis' is analogous to the glycolysis pathway that converts glucose to pyruvate.

...Pacheco F (2016) 3-Bromopyruvic acid inhibits tricarboxylic acid cycle and glutaminolysis in HepG2 cells. Anticancer Res 36:2233-41. ...re inducing cell death. However, cancer cells are also highly dependent of glutaminolysis and tricarboxylic acid cycle (TCA) regarding survival and 3BrPA action in t

...e_dehydrogenase]. mtGDH is not part of the TCA cycle, but is involved in [[glutaminolysis]] as an [[anaplerosis |anaplerotic reaction]].

...s. We use these analogues to show that, under our experimental conditions, glutaminolysis-induced activation of mTORC1 can be uncoupled from PHD activity. Therefore,

...conditions. There are two sources of lactate in cultured cells, oxidative glutaminolysis and reductive glycolysis. Only the latter is measured in the CR ratio as a ...pirometric ratio, Cultured cells, Anaerobic pathways, Lactate production, Glutaminolysis

...enzyme 1, in advanced colon cancer. Moreover, pharmaceutical inhibition of glutaminolysis sensitizes tumour cells to HMGB1 providing a basis for a therapeutic strate

...input for OXPHOS from the elevated glycolysis, which together with ongoing glutaminolysis maintain a virtually unchanged respiration. Similar OXPHOS revival may expl |keywords=Cancer mitochondria, Glutaminolysis, HepG2 cells, Hypoxia-inducible factor, Non-canonical response to hypoxia,

== ME, aging, cancer and glutaminolysis == ...ost abundant single amino acid in plasma, tissues and cell culture media. 'Glutaminolysis' is analogous to the glycolysis pathway that converts glucose to pyruvate (

...]] in the mitochondrial matrix. The G-pathway plays an important role in [[glutaminolysis]]. :::: Glutaminolysis: Glutamate derived from hydrolyzation of glutamine is an important aerobic

...y macrophages during homeostasis in mice. In addition, impaired macrophage glutaminolysis exacerbates atherosclerosis, a condition during which, efficient apoptotic

...ld-type IDH1 and IDH2, notably under shifts toward reductive carboxylation glutaminolysis or changes in other enzymes, lead to “intermediate” 0.01–0.1 mM 2HG

...cycle substrates between α-ketoglutarate and malate despite high rates of glutaminolysis, as determined by flux studies with isotopically labeled glutamine. Malate |keywords=Myc (c-Myc), Warburg effect, Fatty acid oxidation, Glutaminolysis, Pyruvate carboxylase (PC), Reverse carboxylation, Tricarboxylic acid cycle

...nka J, Smolkova K, Dvorak A, Vitek L, Jezek P (2013) Reverse carboxylation glutaminolysis in breast cancer cells. Mitochondr Physiol Network 18.08. ...truncated after citrate synthase; or as reductive carboxylation ("anoxic") glutaminolysis (RCG), using the only two enzymes of Krebs cycle acting in the reversed mod

...PM, Gnaiger E (1994) A thermochemical study of the producion of lactate by glutaminolysis and glycolysis in mouse macrophage hybridoma cells. In: ''What is Controlli

...erial needs via enhanced synthetic pathways, including aerobic glycolysis, glutaminolysis, fatty acid synthesis (FAS), and pentose phosphate pathway (PPP). To surviv

...oxylic acid cycle enzymes, and upregulation of de novo lipid synthesis and glutaminolysis. These alterations are pivotal to the development and maintenance of the ma

...production and survival, including mitochondrial respiration, glycolysis, glutaminolysis, and fatty acid metabolism. Because of metabolic plasticity, CSCs can switc

...nd out in the tumor phenotype and that require intact mitochondria such as glutaminolysis will be addressed. Furthermore, comments will be made as to how the peculia

:::* Protocol focused on the analysis of glutamate anaplerotic pathway/glutaminolysis in permeabilized cells (ce-pce).

...trigger changes in distinct metabolic processes, including glycolysis and glutaminolysis, extrinsic and intrinsic mitochondrial uncoupling, and fatty acid oxidation

...ld-type IDH1 and IDH2, notably under shifts toward reductive carboxylation glutaminolysis or changes in other enzymes, lead to “intermediate” 0.01–0.1 mM 2HG

...Warburg type metabolism, characterized by increased aerobic glycolysis and glutaminolysis, concomitant with increased ammonia and lactate production and elevated lev

...ifferent metabolic pathways such as glycolysis, pentose phosphate pathway, glutaminolysis, and lipid oxidation during secondary injury and recovery, and (c) how immu

:::* Protocol focused on analysis of glutamate anaplerotic pathway/glutaminolysis.

...malignancy. We quantified CO₂-dependent reductive carboxylation glutaminolysis (RCG) and CO₂-independent 2HG production in HTB-126 and MDA-MB-2

...asiulionis MG, Rossignol R, Rumjanek FD, Amoedo ND (2016) Enhanced OXPHOS, glutaminolysis and beta-oxidation constitute the metastatic phenotype of melanoma cells. h

.... The rate of lactate production ― corrected for the fraction generated by glutaminolysis ― is proposed as the appropriate way to estimate glycolytic flux. In gene

Our results show that glutaminolysis, an important metabolic pathway in hSCs for lactate production, is represse ...lucose consumption was not affected. These data indicates a suppression of glutaminolysis, however, it is not clear which metabolic pathway is compensating it to fos

...y. The rate of lactate production, corrected for the fraction generated by glutaminolysis, is proposed as the appropriate way to estimate glycolytic flux. In general

...by [2]). To keep TCA running in the absence of pyruvate, cancer cells use glutaminolysis, which involves deamination of glutamine, yielding glutamate and ammonia. G

| '''Coordination of glutaminolysis and glycolysis in cancer cells''' ...hondrial NADH-linked malic enzyme 2 (ME2) does not only play a key role in glutaminolysis, but its enforced expression suppresses senescence, whereas downregulation

...be measured additionally through glycolysis, pentose phosphate pathway and glutaminolysis using ²H/¹³C NMR to complement the respiratory and fl

...[Oroboros Laboratories|Oroboros O2k-Laboratory]], Project: Coordination of glutaminolysis and glycolysis in PC3 prostate cancer cells. - [[Media:20190711_Abstract_Mi ...Jessica Di Paola]]: Traces from last experiments, Project: Coordination of glutaminolysis and glycolysis in PC3 prostate cancer cells. - [[Media:20190711_Abstract_Mi

| Coordination of glutaminolysis and glycolysis in PC3 prostate cancer cells ...ssica|Di Paola Floriana Jessica]] (Germany): [[TRANSMIT]]: Coordination of glutaminolysis and glycolysis in PC3 prostate cancer cells. Jun 17 - Sept 28.

...ystwyth, Innsbruck) A thermochemical study of the production of lactate by glutaminolysis and glycolysis in mouse macrophage hybridoma cells. p 226. [[Kemp 1994 BTK-

...tabolic flux through (a) glycolysis, (b) pentose phosphate pathway and (c) glutaminolysis using 2H/13C NMR.

...ciences, Prague, CZ||[[Zelenka 2013 Abstract MiP2013|Reverse carboxylation glutaminolysis in breast cancer cells]]||C4-06 Poster

...M, Gnaiger E (1994) A thermochemical study of the production of lactate by glutaminolysis and glycolysis in mouse macrophage hybridoma cells. In What is Controlling

...M, Gnaiger E (1994) A thermochemical study of the production of lactate by glutaminolysis and glycolysis in mouse macrophage hybridoma cells. In What is Controlling

...M, Gnaiger E (1994) A thermochemical study of the production of lactate by glutaminolysis and glycolysis in mouse macrophage hybridoma cells. In What is Controlling

...M, Gnaiger E (1994) A thermochemical study of the production of lactate by glutaminolysis and glycolysis in mouse macrophage hybridoma cells. - [[Kemp 1994 BTK-226 |