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 YearReferenceCouplingPathwayPreparationOrganismTissue;cell
Gvozdjakova 2020 Diagnostics (Basel)2020Gvozdjáková A, Sumbalová Z, Kucharská J, Komlósi M, Rausová Z, Vančová O, Számošová M, Mojto V (2020) Platelet mitochondrial respiration, endogenous coenzyme Q10 and oxidative stress in patients with chronic kidney disease. Diagnostics (Basel) 10:176.LEAK
ROUTINE
OXPHOS
ET
N
S
NS
ROX
Permeabilized cells
Intact cells
HumanPlatelet
Cubizolle 2020 J Cell Mol Med2020Cubizolle A, Cia D, Moine E, Jacquemot N, Guillou L, Rosell M, Angebault-Prouteau C, Lenaers G, Meunier I, Vercauteren J, Durand T, Crauste C, Brabet P (2020) Isopropyl-phloroglucinol-DHA protects outer retinal cells against lethal dose of all-trans-retinal. J Cell Mol Med 24:5057-69.LEAK
OXPHOS
ET
N
S
CIV
NS
Permeabilized cellsRatEndothelial;epithelial;mesothelial cell
Maeda 2020 J Cell Mol Med2020Maeda H, Kami D, Maeda R, Murata Y, Jo JI, Kitani T, Tabata Y, Matoba S, Gojo S (2020) TAT-dextran-mediated mitochondrial transfer enhances recovery from models of reperfusion injury in cultured cardiomyocytes. J Cell Mol Med 24:5007-20.LEAK
ROUTINE
OXPHOS
ET
N
ROX
Isolated mitochondria
Intact cells
RatHeart
Hayes 2020 Nutrients2020Hayes P, Fergus C, Ghanim M, Cirzi C, Burtnyak L, McGrenaghan CJ, Tuorto F, Nolan DP, Kelly VP (2020) Queuine micronutrient deficiency promotes Warburg metabolism and reversal of the mitochondrial ATP synthase in HeLa cells. Nutrients 12:E871.LEAK
ROUTINE
OXPHOS
ET
N
S
Gp
CIV
ROX
Permeabilized cells
Intact cells
HumanHeLa
Tichanek 2020 Sci Rep2020Tichanek F, Salomova M, Jedlicka J, Kuncova J, Pitule P, Macanova T, Petrankova Z, Tuma Z, Cendelin J (2020) Hippocampal mitochondrial dysfunction and psychiatric-relevant behavioral deficits in spinocerebellar ataxia 1 mouse model. Sci Rep 10:5418.LEAK
OXPHOS
ET
N
S
CIV
NS
ROX
HomogenateMouseNervous system
Bloise 2020 Thyroid2020Bloise FF, Santos AT, Brito JT, Andrade CBV, Oliveira TS, Souza AF, Fontes KN, Silva JD, Blanco NG, Silva PL, Rocco PRM, Fliers E, Boelen A, da-Silva WS, Ortiga-Carvalho TM (2020) Sepsis impairs thyroid hormone signaling and mitochondrial function in the mouse diaphragm. Thyroid 30:1079-90.LEAK
OXPHOS
ET
N
CIV
NS
Permeabilized tissueMouseSkeletal muscle
Baggio 2020 Neurotoxicology2020Baggio S, Zenki K, Martins Silva A, Dos Santos TG, Rech G, Lazzarotto G, Dias RD, Mussulini BH, Rico EP, de Oliveira DL (2020) Fetal alcohol spectrum disorders model alters the functionality of glutamatergic neurotransmission in adult zebrafish. Neurotoxicology 78:152-160.LEAK
OXPHOS
ET
N
S
NS
ROX
HomogenateZebrafishNervous system
Yadav 2020 Cell Death Dis2020Yadav SK, Kambis TN, Kar S, Park SY, Mishra PK (2020) MMP9 mediates acute hyperglycemia-induced human cardiac stem cell death by upregulating apoptosis and pyroptosis in vitro. Cell Death Dis 11:186.LEAK
OXPHOS
ET
N
CIV
NS
ROX
Permeabilized cellsHumanHeart
Stem cells
Gruenig 2020 Biochem Pharmacol2020Grünig D, Szabo L, Marbet M, Krähenbühl S (2020) Valproic acid affects fatty acid and triglyceride metabolism in HepaRG cells exposed to fatty acids by different mechanisms. Biochem Pharmacol 177:113860.LEAK
OXPHOS
ET
N
S
DQ
CIV
ROX
Isolated mitochondriaMouseLiver
Song 2020 Life Sci2020Song K, Zhang Y, Ga Q, Bai Z, Ge RL (2020) High-altitude chronic hypoxia ameliorates obesity-induced non-alcoholic fatty liver disease in mice by regulating mitochondrial and AMPK signaling. Life Sci 252:117633.LEAK
OXPHOS
ET
F
N
NS
HomogenateMouseLiver
Khamoui 2020 Physiol Genomics2020Khamoui AV, Tokmina-Roszyk D, Rossiter HB, Fields GB, Visavadiya NP (2020) Hepatic proteome analysis reveals altered mitochondrial metabolism and suppressed acyl-CoA synthetase-1 in colon-26 tumor-induced cachexia. Physiol Genomics 52:203-16.LEAK
OXPHOS
ET
N
NS
Intact cellsMouseLiver
Schoepf 2020 Nat Commun2020Schöpf Bernd, Weissensteiner Hansi, Schäfer Georg, Fazzini Federica, Charoentong Pornpimol, Naschberger Andreas, Rupp Bernhard, Fendt Liane, Bukur Valesca, Giese Irina, Sorn Patrick, Sant’Anna-Silva Ana Carolina, Iglesias-Gonzalez Javier, Sahin Ugur, Kronenberg Florian, Gnaiger Erich, Klocker Helmut (2020) OXPHOS remodeling in high-grade prostate cancer involves mtDNA mutations and increased succinate oxidation. https://doi.org/10.1038/s41467-020-15237-5LEAK
ROUTINE
OXPHOS
ET
N
S
NS
Permeabilized cells
Permeabilized tissue
HumanGenital
Other cell lines
Xia 2020 Biomed Res Int2020Xia W, Wang Q, Lu Y, Hu Y, Zhang X, Zhang J, Liu D, Song J, Zhu Z, Liu D, Zhang H (2020) Transient receptor potential channel canonical type 3 deficiency antagonizes myofibroblast transdifferentiation in vivo. Biomed Res Int 2020:1202189.LEAK
ROUTINE
OXPHOS
ET
N
S
NS
ROX
Permeabilized cells
Intact cells
HumanFibroblast
Jayakumari 2020 J Diabetes2020Jayakumari NR, Rajendran RS, Sivasailam A, Vimala SS, Nanda S, Manjunatha S, Pillai VV, Karunakaran J, Gopala S (2020) Impaired substrate-mediated cardiac mitochondrial complex I respiration with unaltered regulation of fatty acid metabolism and oxidative stress status in type 2 diabetic Asian Indians. J Diabetes 12:542-55.LEAK
OXPHOS
ET
F
N
S
NS
ROX
Isolated mitochondriaHumanHeart
Ferreira 2020 PLoS Genet2020Ferreira N, Andoniou CE, Perks KL, Ermer JA, Rudler DL, Rossetti G, Periyakaruppiah A, Wong JKY, Rackham O, Noakes PG, Degli-Esposti MA, Filipovska A (2020) Murine cytomegalovirus infection exacerbates complex IV deficiency in a model of mitochondrial disease. PLoS Genet 16:e1008604.LEAK
OXPHOS
ET
N
ROX
Isolated mitochondriaMouseLiver
Vulczak 2020 Cells2020Vulczak A, Souza AO, Ferrari GD, Azzolini AECS, Pereira-da-Silva G, Alberici LC (2020) Moderate exercise modulates tumor metabolism of triple-negative breast cancer. Cells 9:E628.LEAK
OXPHOS
ET
N
ROX
Permeabilized cellsMouseEndothelial;epithelial;mesothelial cell
Brand 2020 J Clin Med2020Brand S, Ebner K, Mikoteit T, Lejri I, Gerber M, Beck J, Holsboer-Trachsler E, Eckert A (2020) Influence of regular physical activity on mitochondrial activity and symptoms of burnout-an interventional pilot study. J Clin Med 9:E667.LEAK
OXPHOS
ET
N
CIV
ROX
Permeabilized cellsHumanLymphocyte
MitoEAGLE muscle 12020Doerrier C, Gama-Perez P, Distefano G, Pesta D, Soendergaard SD, Chroeis KM, Gonzalez-Franquesa A, Goodpaster BH, Coen P, Larsen S, Gnaiger E, Garcia-Roves PM (2020) Inter-laboratory harmonization of respiratory protocols in permeabilized human muscle fibers. - Updated: 2020-03-08LEAK
OXPHOS
ET
N
NS
S
ROX
Permeabilized tissueHumanSkeletal muscle
D'Souza 2020 Nutrients2020D'Souza K, Mercer A, Mawhinney H, Pulinilkunnil T, Udenigwe CC, Kienesberger PC (2020) Whey peptides stimulate differentiation and lipid metabolism in adipocytes and ameliorate lipotoxicity-induced insulin resistance in muscle cells. Nutrients 12:E425.LEAK
ET
F
N
Permeabilized cellsMouseSkeletal muscle
Fat
Pajuelo-Reguera 2020 Cells2020Pajuelo Reguera David, Čunátová Kristýna, Vrbacký Marek, Pecinová Alena, Houštěk Josef, Mráček Tomáš, Pecina Petr (2020) Cytochrome c oxidase subunit 4 isoform exchange results in modulation of oxygen affinity. Cells 9:E443.OXPHOS
ET
N
S
Gp
NS
Other combinations
Permeabilized cells
Oxidase;biochemical oxidation
HumanHEK
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