Difference between revisions of "R/E control ratio"

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R/E control ratio

Description

The ROUTINE control ratio (R/E coupling control ratio) is the ratio of (partially coupled) ROUTINE respiration and (noncoupled) ET capacity. The R/E control ratio is an expression of how close ROUTINE respiration operates to ET capacity.

Abbreviation: R/E

Reference: Gnaiger 2014 MitoPathways

MitoPedia concepts: Respiratory control ratio

Boundaries of the ROUTINE control ratio

R/E increases due to (i) high ATP demand and ADP-stimulated ROUTINE respiration, (ii) partial uncoupling, and (iii) limitation of oxidative capacity by defects of substrate oxidation and complexes of the ET-pathway. The corresponding inverse ratio is the uncoupling control ratio, UCR, which can be seen as an index of apparent ET-pathway excess capacity. The lower boundary of R/E is the L/E flux control ratio, whereas the upper boundary is set by the P/E flux control ratio (OXPHOS/ET capacity).

Biochemical coupling efficiency: from 0 to <1

More details: »Biochemical coupling efficiency

Compare:

Excess E-R capacity factor, j_ExR = (E-R)/E = 1-R/E
ROUTINE coupling efficiency, j_≈R = ≈R/R = (R-L)/R = 1-L/R
NetROUTINE control ratio, ≈R/E = (R-L)/E

List of publications: ROUTINE and ET-pathway

@@ Line 1: / Line 1: @@
 {{MitoPedia
 |abbr=''R/E''
-|description=[[Image:R over E.jpg|50 px|ROUTINE control ratio]] The '''ROUTINE control ratio''' (''R/E'' coupling control ratio) is the ratio of (partially coupled) [[ROUTINE respiration]] and (noncoupled) [[ETS capacity]].  The ''R/E'' control ratio is an expression of how close ROUTINE respiration operates to ETS capacity.
+|description=[[Image:R over E.jpg|50 px|ROUTINE control ratio]] The '''ROUTINE control ratio''' (''R/E'' coupling control ratio) is the ratio of (partially coupled) [[ROUTINE respiration]] and (noncoupled) [[ET capacity]].  The ''R/E'' control ratio is an expression of how close ROUTINE respiration operates to ET capacity.
 |info=[[Gnaiger 2014 MitoPathways]]
 }}
@@ Line 9: / Line 9: @@
 == Boundaries of the ROUTINE control ratio ==
-:::: ''R/E'' increases due to (i) high ATP demand and ADP-stimulated ROUTINE respiration, (ii) partial uncoupling, and (iii) limitation of oxidative capacity by defects of substrate oxidation and complexes of the ETS. The corresponding inverse ratio is the uncoupling control ratio, UCR, which can be seen as an index of apparent ETS excess capacity. The lower boundary of ''R/E'' is the ''[[L/E]]'' flux control ratio, whereas the upper boundary is set by the ''[[P/E]]'' flux control ratio (OXPHOS/ETS capacity).
+:::: ''R/E'' increases due to (i) high ATP demand and ADP-stimulated ROUTINE respiration, (ii) partial uncoupling, and (iii) limitation of oxidative capacity by defects of substrate oxidation and complexes of the ET-pathway. The corresponding inverse ratio is the uncoupling control ratio, UCR, which can be seen as an index of apparent ET-pathway excess capacity. The lower boundary of ''R/E'' is the ''[[L/E]]'' flux control ratio, whereas the upper boundary is set by the ''[[P/E]]'' flux control ratio (OXPHOS/ET capacity).
 == Biochemical coupling efficiency: from 0 to <1 ==
@@ Line 19: / Line 19: @@
-== List of publications: ROUTINE and ETS ==
+== List of publications: ROUTINE and ET-pathway ==
 {{#ask:[[Category:Publications]] [[Coupling states::ROUTINE]] [[Coupling states::ETS]]
+|?Was published in year=Year
+|?Has title=Reference
+|?Mammal and model
+|?Tissue and cell
+|?Stress
+|?Diseases
+|format=broadtable
+|limit=5000
+|offset=0
+|sort=Was published in year
+|order=descending
+}}
+{{#ask:[[Category:Publications]] [[Coupling states::ROUTINE]] [[Coupling states::ET-pathway]]
 |?Was published in year=Year
 |?Has title=Reference