Preston 2023 Academic Press

Preston G, El Soufi El Sabbagh D, Emmerzaal TL, Morava E, Andreazza AC, Rahman S, Kozicz T (2023) Antidepressants, mood-stabilizing drugs, and mitochondrial functions: For better or for worse. In: de Oliveira MR (ed) Mitochondrial intoxication:323-49. Academic Press. https://doi.org/10.1016/B978-0-323-88462-4.00016-X

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Preston G, El Soufi El Sabbagh D, Emmerzaal TL, Morava E, Andreazza AC, Rahman S, Kozicz T (2023) Academic Press

Abstract: Psychiatric manifestations of primary mitochondrial diseases are increasingly recognized, and optimal strategies for managing these represent a significant unmet clinical need for this group of patients with complex multisystem symptomatology and high mortality and morbidity. Secondary mitochondrial dysfunction and oxidative stress have also been implicated in the pathophysiology of various psychiatric diseases. It has been well documented that medications used to treat neuropsychiatric disorders could directly modulate mitochondrial functions. The objective of this book chapter is to review antidepressant drugs and other psychiatric medications that are available for the treatment of psychiatric disorders and the evidence that exists in relation to the mitochondria using these drugs.

• Bioblast editor: Gnaiger E

Correction: FADH₂ and Complex II

FADH₂ is shown as the substrate feeding electrons into Complex II (CII). This is wrong and requires correction - for details see Gnaiger (2024).

Gnaiger E (2024) Complex II ambiguities ― FADH₂ in the electron transfer system. J Biol Chem 300:105470. https://doi.org/10.1016/j.jbc.2023.105470 - »Bioblast link«