NS-pathway control state

high-resolution terminology - matching measurements at high-resolution

NS-pathway control state

Description

The Complex I&II-linked substrate state is induced in mt-preparations by addition of NADH-generating substrates (CI-linked) in combination with succinate (CII-linked). This physiological substrate combination is required for partial reconstiturion of TCA cycle function and convergent electron-input into the Q-junction to compensate for metabolite depletion into the incubation medium. An Additive effect of convergent CI&II electron flow is observed in most types of mitochondria.

Abbreviation: CI&II-linked

Reference: Gnaiger 2014 MitoPathways

MitoPedia O2k and high-resolution respirometry: "SUIT state" is not in the list (O2k hardware, DatLab, Oroboros QM, O2k-Open Support, O2k-Respirometry, O2k-FluoRespirometry) of allowed values for the "MitoPedia O2k and high-resolution respirometry" property. SUIT state"SUIT state" is not in the list (O2k hardware, DatLab, Oroboros QM, O2k-Open Support, O2k-Respirometry, O2k-FluoRespirometry) of allowed values for the "MitoPedia O2k and high-resolution respirometry" property. 

MitoPedia topics: "Respiratory state" is not in the list (Enzyme, Medium, Inhibitor, Substrate and metabolite, Uncoupler, Sample preparation, Permeabilization agent, EAGLE, MitoGlobal Organizations, MitoGlobal Centres, ...) of allowed values for the "MitoPedia topic" property. Respiratory state"Respiratory state" is not in the list (Enzyme, Medium, Inhibitor, Substrate and metabolite, Uncoupler, Sample preparation, Permeabilization agent, EAGLE, MitoGlobal Organizations, MitoGlobal Centres, ...) of allowed values for the "MitoPedia topic" property., Substrate and metabolite