MitoSOX
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Revision as of 12:44, 18 September 2018 by Iglesias-Gonzalez Javier (talk | contribs) (Created page with "MitoSOX<sup>TM</sup> is a fluorescent dye design to target mitochondria in live cells for the detection of anion superoxide (O<sub>2</sub><sup>-Β°</sup>). The oxidation of the...")
MitoSOXTM is a fluorescent dye design to target mitochondria in live cells for the detection of anion superoxide (O2-Β°). The oxidation of the compund by O2-Β° is easily detected in the red spectrum, being selective for O2-Β° but not for other Reactive oxygen species or Reactive nitrogen species.
β’ Readily oxidized by superoxide but not by other ROS- or RNS-generating systems β’ Absorption/emission maxima: ~510/580 nm β’ Use for live cell imaging β’ Rapidly and selectively targeted to the mitochondria