Difference between revisions of "MitoFit"
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'''The O2k-Fluorometer and Mitochondrial Physiology - [[K-Regio_MitoCom Tyrol_(de)|Das O2k-Fluorometer und mitochondriale Physiologie (deutsch)]]''' | '''The O2k-Fluorometer and Mitochondrial Physiology - [[K-Regio_MitoCom Tyrol_(de)|Das O2k-Fluorometer und mitochondriale Physiologie (deutsch)]]''' | ||
The aim of the project is the development, evaluation and application of a new high-resolution instrument, the '''O2k-Fluorometer''', which builds upon the [http://www.oroboros.at/index.php?oxygraph OROBOROS Oxygraph-2k] developed and extended since 2001 by [http://www.oroboros.at OROBOROS INSTRUMENTS] and [http://www.wgt.at WGT-Elektronik]. The Oxygraph-2k (O2k) provides the instrumental basis for [http://www.oroboros.at/index.php?high-resolution-respirometry high-resolution respirometry (HRR)] and represents world-wide the technologically leading instrument for diagnostic evaluation of mitochondrial respiratory function. The integration of optical devices (fluorometry, spectrophotometry) into the O2k opens up the potential for the analysis of various diagnostically significant cellular functions, simultaneously with the measurement of mitochondrial respiration. In particular, HRR will be combined with the fluorometric detection of reactive oxygen species (ROS; oxidative stress) and mitochondrial membrane potential using established fluorescent dyes. This innovation will further establish our technological leadership, and will extend a growing market (presently the O2k is represented in [http://www.oroboros.at/index.php?mipnet-labs 35 countries]). The technological âsole sourceâ status will be systematically secured, as a decisive feature for the successful world-wide export of a high-end diagnostic instrument. | |||
: '''Applicant:''' Medical University of Innsbruck, A.Univ.-Prof. Dr. Erich Gnaiger | |||
: '''Application:''' 2011-04-15; '''Granted:''' 2011-07-13 (total budget ⏠1.05 Mill) | |||
''' | |||
: '''Project duration:''' 2011-05-01 to 2014-04-30 | |||
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'''Project duration:''' 2011-05-01 to 2014-04-30 | |||
*'''[[MitoCom Partners|K-Regio Project Partners]]''': [http://www.oroboros.at/index.php?mitocom-tyrol OROBOROS INSTRUMENTS], WGT Elekronik, Leopold-Franzens University of Innsbruck, Medical University of Innsbruck | *'''[[MitoCom Partners|K-Regio Project Partners]]''': [http://www.oroboros.at/index.php?mitocom-tyrol OROBOROS INSTRUMENTS], WGT Elekronik, Leopold-Franzens University of Innsbruck, Medical University of Innsbruck | ||
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== Financial support == | |||
[[File:K-Regio Icon Englisch 01.jpg|thumb|290px|left]] | |||
[[File:K-Regio Icon.jpg|thumb|290px|right]] | |||
'''Förderung von Wissenschaft, Forschung und Entwicklung (Programm K-Regio); EU-Regionalförderungsprogramm "StÀrkung der regionalen WettbewerbsfÀhigkeit Tirols 2007-2013; Landes- und EU-Förderung''' | '''Förderung von Wissenschaft, Forschung und Entwicklung (Programm K-Regio); EU-Regionalförderungsprogramm "StÀrkung der regionalen WettbewerbsfÀhigkeit Tirols 2007-2013; Landes- und EU-Förderung''' | ||
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LandesrÀtin Patrizia Zoller-Frischauf | LandesrÀtin Patrizia Zoller-Frischauf | ||
[[Category:MitoCom]] | |||
Revision as of 01:51, 14 August 2012
K-Regio Project MitoCom Tyrol
The O2k-Fluorometer and Mitochondrial Physiology - Das O2k-Fluorometer und mitochondriale Physiologie (deutsch)
The aim of the project is the development, evaluation and application of a new high-resolution instrument, the O2k-Fluorometer, which builds upon the OROBOROS Oxygraph-2k developed and extended since 2001 by OROBOROS INSTRUMENTS and WGT-Elektronik. The Oxygraph-2k (O2k) provides the instrumental basis for high-resolution respirometry (HRR) and represents world-wide the technologically leading instrument for diagnostic evaluation of mitochondrial respiratory function. The integration of optical devices (fluorometry, spectrophotometry) into the O2k opens up the potential for the analysis of various diagnostically significant cellular functions, simultaneously with the measurement of mitochondrial respiration. In particular, HRR will be combined with the fluorometric detection of reactive oxygen species (ROS; oxidative stress) and mitochondrial membrane potential using established fluorescent dyes. This innovation will further establish our technological leadership, and will extend a growing market (presently the O2k is represented in 35 countries). The technological âsole sourceâ status will be systematically secured, as a decisive feature for the successful world-wide export of a high-end diagnostic instrument.
- Applicant: Medical University of Innsbruck, A.Univ.-Prof. Dr. Erich Gnaiger
- Application: 2011-04-15; Granted: 2011-07-13 (total budget ⏠1.05 Mill)
- Project duration: 2011-05-01 to 2014-04-30
- K-Regio Project Partners: OROBOROS INSTRUMENTS, WGT Elekronik, Leopold-Franzens University of Innsbruck, Medical University of Innsbruck
Financial support
Förderung von Wissenschaft, Forschung und Entwicklung (Programm K-Regio); EU-Regionalförderungsprogramm "StÀrkung der regionalen WettbewerbsfÀhigkeit Tirols 2007-2013; Landes- und EU-Förderung
- EU-Förderung: ⏠283,295.97
- Landesförderung as Mitteln der Wirtschaftsförderung des Landes Tirol: ⏠283,295.97
- Gesamtförderung: ⏠566,591.95
- Bemessungsgrundlage der förderbaren Kosten: ⏠1,049,010.70
LandesrÀtin Patrizia Zoller-Frischauf
