Difference between revisions of "MitoFit"
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The aim of the project is the development, evaluation and application of a new high-resolution instrument, the '''O2k-Fluorimeter''', which builds upon the [http://www.oroboros.at/index.php?oxygraph OROBOROS Oxygraph-2k] developed and extended since 2001 by [http://www.oroboros.at OROBOROS INSTRUMENTS] and [http://www.wgt.at WGT-Elektronik]. The Oxygraph-2k (O2k) provides the instrumental basis for [http://www.oroboros.at/index.php?high-resolution-respirometry high-resolution respirometry (HRR)] and represents world-wide the technologically leading instrument for diagnostic evaluation of mitochondrial respiratory function. The integration of optical devices (fluorimetry, spectrophotometry) into the O2k opens up the potential for the analysis of various diagnostically significant cellular functions, simultaneously with the measurement of mitochondrial respiration. In particular, HRR will be combined with the fluorimetric detection of reactive oxygen species (ROS; oxidative stress) and mitochondrial membrane potential using established fluorescent dyes. This innovation will further establish our technological leadership, and will extend a growing market (presently the O2k is represented in [http://www.oroboros.at/index.php?mipnet-labs 34 countries]). The technological ‘sole source’ status will be systematically secured, as a decisive feature for the successful world-wide export of a high-end diagnostic instrument. | The aim of the project is the development, evaluation and application of a new high-resolution instrument, the '''O2k-Fluorimeter''', which builds upon the [http://www.oroboros.at/index.php?oxygraph OROBOROS Oxygraph-2k] developed and extended since 2001 by [http://www.oroboros.at OROBOROS INSTRUMENTS] and [http://www.wgt.at WGT-Elektronik]. The Oxygraph-2k (O2k) provides the instrumental basis for [http://www.oroboros.at/index.php?high-resolution-respirometry high-resolution respirometry (HRR)] and represents world-wide the technologically leading instrument for diagnostic evaluation of mitochondrial respiratory function. The integration of optical devices (fluorimetry, spectrophotometry) into the O2k opens up the potential for the analysis of various diagnostically significant cellular functions, simultaneously with the measurement of mitochondrial respiration. In particular, HRR will be combined with the fluorimetric detection of reactive oxygen species (ROS; oxidative stress) and mitochondrial membrane potential using established fluorescent dyes. This innovation will further establish our technological leadership, and will extend a growing market (presently the O2k is represented in [http://www.oroboros.at/index.php?mipnet-labs 34 countries]). The technological ‘sole source’ status will be systematically secured, as a decisive feature for the successful world-wide export of a high-end diagnostic instrument. | ||
====Financial support==== | |||
'''Förderung von Wissenschaft, Forschung und Entwicklung (Programm K-Regio); EU-Regionalförderungsprogramm "Stärkung der regionalen Wettbewerbsfähigkeit Tirols 2007-2013; Landes- und EU-Förderung''' | |||
* EU-Förderung: '''€ 283,295.97''' | |||
* Landesförderung as Mitteln der Wirtschaftsförderung des Landes Tirol: '''€ 283,295.97''' | |||
* Gesamtförderung:''' € 566,591.95''' | |||
* Bemessungsgrundlage der förderbaren Kosten:''' € 1,049,010.70''' | |||
Landesräting Patrizia Zoller-Frischauf | |||
Revision as of 08:39, 18 August 2011
MitoCom Tyrol
The O2k-Fluorimeter and Mitochondrial Physiology - Das O2k-Fluorimeter und mitochondriale Physiologie (deutsch)
Applicant: Medical University of Innsbruck, A.Univ.-Prof. Dr. Erich Gnaiger
Application: 2011-04-15; Granted: 2011-07-13 (total budget € 1.05 Mill)
Project duration: 2011-05-01 to 2014-04-30
The aim of the project is the development, evaluation and application of a new high-resolution instrument, the O2k-Fluorimeter, which builds upon the OROBOROS Oxygraph-2k developed and extended since 2001 by OROBOROS INSTRUMENTS and WGT-Elektronik. The Oxygraph-2k (O2k) provides the instrumental basis for high-resolution respirometry (HRR) and represents world-wide the technologically leading instrument for diagnostic evaluation of mitochondrial respiratory function. The integration of optical devices (fluorimetry, spectrophotometry) into the O2k opens up the potential for the analysis of various diagnostically significant cellular functions, simultaneously with the measurement of mitochondrial respiration. In particular, HRR will be combined with the fluorimetric detection of reactive oxygen species (ROS; oxidative stress) and mitochondrial membrane potential using established fluorescent dyes. This innovation will further establish our technological leadership, and will extend a growing market (presently the O2k is represented in 34 countries). The technological ‘sole source’ status will be systematically secured, as a decisive feature for the successful world-wide export of a high-end diagnostic instrument.
Financial support
Förderung von Wissenschaft, Forschung und Entwicklung (Programm K-Regio); EU-Regionalförderungsprogramm "Stärkung der regionalen Wettbewerbsfähigkeit Tirols 2007-2013; Landes- und EU-Förderung
- EU-Förderung: € 283,295.97
- Landesförderung as Mitteln der Wirtschaftsförderung des Landes Tirol: € 283,295.97
- Gesamtförderung: € 566,591.95
- Bemessungsgrundlage der förderbaren Kosten: € 1,049,010.70
Landesräting Patrizia Zoller-Frischauf
