Difference between revisions of "Linearity"
Harrison DK (talk | contribs) (Created page with "{{MitoPedia |abbr=Linearity |description='''Linearity''' is the ability of the method to produce test results that are proportional, either directly or by a well-defined mathemat...") Β |
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{{MitoPedia | {{MitoPedia | ||
|abbr=Linearity | |abbr=Linearity | ||
|description='''Linearity''' is the ability of the method to produce test results that are proportional, either directly or by a well-defined mathematical transformation, to the concentration of the analyte in samples within a given range. This property is inherent in the [[Beer-Lambert law]] for [[absorbance]] alone, but deviations occur in [[scattering]] media. It is also a property of [[fluorescence]], but a [[fluorophore]] may not exhibit linearity, particularly over a large range of concentrations. Β | |description='''Linearity''' is the ability of the method to produce test results that are proportional, either directly or by a well-defined mathematical transformation, to the concentration of the analyte in samples within a given range. This property is inherent in the [[Beer-Lambert law]] for [[absorbance]] alone, but deviations occur in [[scattering]] media. It is also a property of [[fluorescence]], but a [[fluorophore]] may not exhibit linearity, particularly over a large range of concentrations. | ||
|info=Paul WL (1991) USP perspectives on analytical methods evaluation. Pharm. Technol. 15: 130-141. Elwell CE (1995) A practical users guide to near infrared spectroscopy. Hamamatsu Photonics, 155pp. | |info=Paul WL (1991) USP perspectives on analytical methods evaluation. Pharm. Technol. 15: 130-141. Elwell CE (1995) A practical users guide to near infrared spectroscopy. Hamamatsu Photonics, 155pp. | ||
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{{MitoPedia methods | {{MitoPedia methods | ||
|mitopedia method= | |mitopedia method=Fluorometry, Spectrophotometry | ||
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{{MitoPedia topics}} | {{MitoPedia topics}} |
Revision as of 14:22, 21 November 2011
Description
Linearity is the ability of the method to produce test results that are proportional, either directly or by a well-defined mathematical transformation, to the concentration of the analyte in samples within a given range. This property is inherent in the Beer-Lambert law for absorbance alone, but deviations occur in scattering media. It is also a property of fluorescence, but a fluorophore may not exhibit linearity, particularly over a large range of concentrations.
Abbreviation: Linearity
Reference: Paul WL (1991) USP perspectives on analytical methods evaluation. Pharm. Technol. 15: 130-141. Elwell CE (1995) A practical users guide to near infrared spectroscopy. Hamamatsu Photonics, 155pp.
MitoPedia methods:
Fluorometry,
Spectrophotometry