Difference between revisions of "Kuznetsov 1999 Transplant Proc"
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|journal=Transplant Proc | |journal=Transplant Proc | ||
|abstract=STUDIES of mitochondrial bioenergetics yield a quantitative assessment of cell injury after organ storage.<sup>1-4</sup> To reduce artifacts of mitochondrial isolation, we optimized high-resolution respirometry with permeabilized cells and muscle fibers for investigation of mitochondrial cold ischemia/reperfusion (CIR) injury. | |abstract=STUDIES of mitochondrial bioenergetics yield a quantitative assessment of cell injury after organ storage.<sup>1-4</sup> To reduce artifacts of mitochondrial isolation, we optimized high-resolution respirometry with permeabilized cells and muscle fibers for investigation of mitochondrial cold ischemia/reperfusion (CIR) injury. | ||
|mipnetlab=AT_Innsbruck_Gnaiger E | |mipnetlab=AT_Innsbruck_Gnaiger E | ||
|discipline=Mitochondrial Physiology, Biomedicine | |discipline=Mitochondrial Physiology, Biomedicine | ||
}} | }} | ||
{{Labeling | {{Labeling | ||
|organism=Rat | |organism=Rat | ||
|tissues=Heart | |tissues=Heart | ||
|preparations=Permeabilized cells, Permeabilized tissue | |preparations=Permeabilized cells, Permeabilized tissue | ||
|injuries=Ischemia-Reperfusion; Preservation | |||
|topics=Substrate; Glucose; TCA Cycle | |||
|couplingstates=OXPHOS | |couplingstates=OXPHOS | ||
| | |instruments=Oxygraph-2k | ||
|discipline=Mitochondrial Physiology, Biomedicine | |discipline=Mitochondrial Physiology, Biomedicine | ||
}} | }} | ||
Revision as of 15:55, 28 August 2014
| Kuznetsov AV, Brandacher G, Steurer W, Margreiter R, Gnaiger E (1999) Estimation of mitochondrial damage in heart preservation. Transplant Proc 31: 992. |
Kuznetsov AV, Brandacher G, Steurer W, Margreiter R, Gnaiger E (1999) Transplant Proc
Abstract: STUDIES of mitochondrial bioenergetics yield a quantitative assessment of cell injury after organ storage.1-4 To reduce artifacts of mitochondrial isolation, we optimized high-resolution respirometry with permeabilized cells and muscle fibers for investigation of mitochondrial cold ischemia/reperfusion (CIR) injury.
• O2k-Network Lab: AT_Innsbruck_Gnaiger E
Labels:
Stress:Ischemia-Reperfusion; Preservation"Ischemia-Reperfusion; Preservation" is not in the list (Cell death, Cryopreservation, Ischemia-reperfusion, Permeability transition, Oxidative stress;RONS, Temperature, Hypoxia, Mitochondrial disease) of allowed values for the "Stress" property. Organism: Rat Tissue;cell: Heart Preparation: Permeabilized cells, Permeabilized tissue
Regulation: Substrate; Glucose; TCA Cycle"Substrate; Glucose; TCA Cycle" is not in the list (Aerobic glycolysis, ADP, ATP, ATP production, AMP, Calcium, Coupling efficiency;uncoupling, Cyt c, Flux control, Inhibitor, ...) of allowed values for the "Respiration and regulation" property. Coupling state: OXPHOS
HRR: Oxygraph-2k
