Difference between revisions of "E-L net ET capacity"
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Communicated by [[Gnaiger E]] 2014-09-21, edited 2015-01-19. | |||
[[File:EPL-free and excess.jpg|right|300px|thumb|[[Gnaiger 2014 MitoPathways |The Blue Book 2014]]: Fig. 2.4.]] | [[File:EPL-free and excess.jpg|right|300px|thumb|[[Gnaiger 2014 MitoPathways |The Blue Book 2014]]: Fig. 2.4.]] | ||
Revision as of 21:02, 23 August 2018
Description
The Free ET-capacity, βE, is the ET-capacity corrected for LEAK respiration, βE = E-L. βE is the respiratory capacity potentially available for ion transport and phosphorylation of ADP to ATP. Oxygen consumption in the ET-pathway state, therefore, is partitioned into the free ET-capacity, βE, and LEAK respiration, LP, compensating for proton leaks, slip and cation cycling: E = βE+LP (see free OXPHOS capacity).
Abbreviation: βE
Reference: Gnaiger 2014 MitoPathways
MitoPedia concepts:
Respiratory state,
Recommended,
Ergodynamics
MitoPedia topics:
EAGLE
Communicated by Gnaiger E 2014-09-21, edited 2015-01-19.
Coupling control states for βE
- Reference state, ZX: ET-capacity; E = EΒ΄-Rox
- Background state, YX: LEAK respiration; L = LΒ΄-Rox
- Metabolic control variable, X=ZX-YX: Scope of uncoupler stimulation, Free ET-capacity; βE = E-L
Flux control factor
- Β» Flux control factor, FCF
- Coupling control factor, 1-YX/ZX: E-L coupling control factor, ET-coupling efficiency: jβE = βE/E =(E-L)/E = 1-L/E
Compare
- mt-Preparations Free OXPHOS capacity, βP = P-L
- Intact cells Free ROUTINE activity, βR = R-L