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From Bioblast
Year | Reference | Coupling | Pathway | Preparation | Organism | Tissue;cell | |
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Franco 2020 bioRxiv | 2020 | Franco JLM, Genoula M, Corral D, Duette G, Ferreyra M, Maio M, Dolotowicz MB, Aparicio-Trejo OE, Patiño-Martínez E, Fuentes F, Soldan V, Moraña EJ, Palmero D, Ostrowski M, Schierloh P, Sánchez-Torres C, Hernández-Pando R, Pedraza-Chaverri J, Rombouts Y, Layre E, Hudrisier D, Vérollet C, Neyrolles O, Sasiain MC, Lugo-Villarino G, Balboa L (2020) Host-derived lipids from tuberculous pleurisy impair macrophage microbicidal-associated metabolic activity. bioRxiv doi: https://doi.org/10.1101/2020.03.23.001818 . | LEAK ROUTINE | N S CIV ROX | Intact cells | Human | Macrophage-derived |
Frangos 2023 J Biol Chem | 2023 | Frangos SM, DesOrmeaux GJ, Holloway GP (2023) Acidosis attenuates CPT-I supported bioenergetics as a potential mechanism limiting lipid oxidation. https://doi.org/10.1016/j.jbc.2023.105079 | LEAK OXPHOS | F N S NS | Permeabilized tissue Isolated mitochondria | Mouse | Skeletal muscle |
Franko 2016 Diabetes | 2016 | Franko A, Huypens P, Neschen S, Irmler M, Rozman J, Rathkolb B, Neff F, Prehn C, Dubois G, Baumann M, Massinger R, Gradinger D, Przemeck GK, Repp B, Aichler M, Feuchtinger A, Schommers P, Stöhr O, Sanchez-Lasheras C, Adamski J, Peter A, Prokisch H, Beckers J, Walch AK, Fuchs H, Wolf E, Schubert M, Wiesner RJ, Hrabě de Angelis M (2016) Bezafibrate improves insulin sensitivity and metabolic flexibility in STZ-treated diabetic mice. Diabetes 65:2540-52. | LEAK OXPHOS | N S CIV ROX | Permeabilized cells Permeabilized tissue | Human | Skeletal muscle Fibroblast |
Frederick 2014 J Biol Chem | 2014 | Frederick DW, Davis JG, Dávila A Jr, Agarwal B, Michan S, Puchowicz MA, Nakamaru-Ogiso E, Baur JA (2014) Increasing NAD synthesis in muscle via nicotinamide phosphoribosyltransferase is not sufficient to promote oxidative metabolism.. J Biol Chem. 290:1546-58. | LEAK OXPHOS | F N S ROX | Isolated mitochondria | Mouse | Skeletal muscle |
Frey 2016 Biochim Biophys Acta | 2016 | Frey S, Geffroy G, Desquiret-Dumas V, Gueguen N, Bris C, Belal S, Amati-Bonneau P, Chevrollier A, Barth M, Henrion D, Lenaers G, Bonneau D, Reynier P, Procaccio V (2016) The addition of ketone bodies alleviates mitochondrial dysfunction by restoring complex I assembly in a MELAS cellular model. Biochim Biophys Acta 1863:284-91. | ROUTINE LEAK ET | N S NS | Permeabilized cells Intact cells | Human | Nervous system |
Freyer 2010 Nucleic Acids Res | 2010 | Freyer C, Park CB, Ekstrand MI, Shi Y, Khvorostova J, Wibom R, Falkenberg M, Gustafsson CM, Larsson NG (2010) Maintenance of respiratory chain function in mouse hearts with severely impaired mtDNA transcription. Nucleic Acids Res 38:6577–88. | N S CIV | Isolated mitochondria | Mouse | Heart | |
Freyer 2012 Nat Genet | 2012 | Freyer C, Cree LM, Mourier A, Stewart JB, Koolmeister C, Milenkovic D, Wai T, Floros VI, Hagström E, Chatzidaki EE, Wiesner RJ, Samuels DC, Larsson NG, Chinnery PF (2012) Variation in germline mtDNA heteroplasmy is determined prenatally but modified during subsequent transmission. Nat Genet 44:1282-5. | ET | N S | Isolated mitochondria | Mouse | Heart Liver |
Friederich 2017 Hum Mol Genet | 2017 | Friederich MW, Erdogan AJ, Coughlin CR 2nd, Elos MT, Jiang H, O'Rourke CP, Lovell MA, Wartchow E, Gowan K, Chatfield KC, Chick WS, Spector EB, Van Hove JLK, Riemer J (2017) Mutations in the accessory subunit NDUFB10 result in isolated complex I deficiency and illustrate the critical role of intermembrane space import for complex I holoenzyme assembly. Hum Mol Genet 26:702-16. | ROUTINE OXPHOS ET LEAK | N S CIV NS ROX | Permeabilized cells Intact cells | Human | Fibroblast |
Friederich 2018 Nat Commun | 2018 | Friederich MW, Timal S, Powell CA, Dallabona C, Kurolap A, Palacios-Zambrano S, Bratkovic D, Derks TGJ, Bick D, Bouman K, Chatfield KC, Damouny-Naoum N, Dishop MK, Falik-Zaccai TC, Fares F, Fedida A, Ferrero I, Gallagher RC, Garesse R, Gilberti M, González C, Gowan K, Habib C, Halligan RK, Kalfon L, Knight K, Lefeber D, Mamblona L, Mandel H, Mory A, Ottoson J, Paperna T, Pruijn GJM, Rebelo-Guiomar PF, Saada A, Sainz B Jr, Salvemini H, Schoots MH, Smeitink JA, Szukszto MJ, Ter Horst HJ, van den Brandt F, van Spronsen FJ, Veltman JA, Wartchow E, Wintjes LT, Zohar Y, Fernández-Moreno MA, Baris HN, Donnini C, Minczuk M, Rodenburg RJ, Van Hove JLK (2018) Pathogenic variants in glutamyl-tRNAGln amidotransferase subunits cause a lethal mitochondrial cardiomyopathy disorder. Nat Commun 9:4065. | ROUTINE OXPHOS ET | N S CIV NS ROX | Permeabilized cells Intact cells | Human Fungi | Fibroblast |
Friederich 2019 Mol Genet Metab | 2019 | Friederich MW, Perez FA, Knight KM, Van Hove RA, Yang SP, Saneto RP, Van Hove JLK (2019) Pathogenic variants in NUBPL result in failure to assemble the matrix arm of complex I and cause a complex leukoencephalopathy with thalamic involvement. Mol Genet Metab 129:236-42. | OXPHOS ET | N S CIV NS | Human | Fibroblast | |
Fuchs 2020 J Funct Foods | 2020 | Fuchs C, Bakuradze T, Steinke R, Grewal R, Eckert GP, Richling E (2020) Polyphenolic composition of extracts from winery by-products and effects on cellular cytotoxicity and mitochondrial functions in HepG2 cells. J Funct Foods 70:103988. | LEAK OXPHOS ET | N S CIV NS ROX | Permeabilized cells | Human | Liver |
Fuhrmann 2018 Cell Mol Life Sci | 2018 | Fuhrmann DC, Wittig I, Dröse S, Schmid T, Dehne N, Brüne B (2018) Degradation of the mitochondrial complex I assembly factor TMEM126B under chronic hypoxia. Cell Mol Life Sci 75:3051-67. | LEAK ROUTINE OXPHOS ET | N S ROX | Isolated mitochondria Intact cells | Human | |
Furihata 2021 Commun Biol | 2021 | Furihata T, Takada S, Kakutani N, Maekawa S, Tsuda M, Matsumoto J, Mizushima W, Fukushima A, Yokota T, Enzan N, Matsushima S, Handa H, Fumoto Y, Nio-Kobayashi J, Iwanaga T, Tanaka S, Tsutsui H, Sabe H, Kinugawa S (2021) Cardiac-specific loss of mitoNEET expression is linked with age-related heart failure. Commun Biol 4:138. | LEAK OXPHOS ET | N S NS ROX | Isolated mitochondria | Mouse | Heart |
Gainutdinov 2015 Arch Biochem Biophys | 2015 | Gainutdinov T, Molkentin JD, Siemen D, Ziemer M, Debska-Vielhaber G, Vielhaber S, Gizatullina Z, Orynbayeva Z, Gellerich FN (2015) Knockout of cyclophilin D in Ppif(-/-) mice increases stability of brain mitochondria against Ca(2+) stress. Arch Biochem Biophys 579:40-6. | LEAK OXPHOS | N S ROX | Isolated mitochondria | Mouse | Nervous system |
Gainutdinov 2017 MITOEAGLE Obergurgl | Different ways of reactive oxygen species (ROS) formation by brain mitochondria. | N S Gp | Isolated mitochondria | Mouse Rat | Nervous system | ||
Galina 2012 Abstract Bioblast | Simonin V, Galina A (2012) Nitric oxide inhibits succinate dehydrogenase-driven oxygen consumption in potato tuber mitochondria in an oxygen tension-independent manner. Mitochondr Physiol Network 17.12. | OXPHOS | N S NS | ||||
Galina 2013 Abstract MiP2013 | Galina A, Messeder DJM, Camacho-Pereira J, Pereira da Silva AP, Rodrigues-Ferreira C (2013) Effects of antitumor alkylating agent 3-bromopyruvate on energy transducing pathways in hepatoma HepG2, liver mitochondria and SERCA: Is there any role for mitochondrial hexokinase activity? Mitochondr Physiol Network 18.08. | LEAK ROUTINE OXPHOS ET | N S | Permeabilized cells Isolated mitochondria Enzyme Intact cells | Rat | Skeletal muscle Nervous system Liver Other cell lines | |
Galina 2015 Abstract MiP2015 | High intensity interval training (HIIT) induces specific changes in respiration and electron leakage in the mitochondria of different rat skeletal muscles. | LEAK | N S ROX | Permeabilized tissue | Rat | Skeletal muscle | |
Galli 2013 J Exp Biol | 2013 | Galli GL, Lau GY, Richards JG (2013) Beating oxygen: chronic anoxia exposure reduces mitochondrial F1FO-ATPase activity in turtle (Trachemys scripta) heart. J Exp Biol 216:3283-93. | LEAK OXPHOS | N S CIV | Permeabilized tissue Isolated mitochondria | Reptiles | Heart |
Galli 2016 Am J Physiol Regul Integr Comp Physiol | 2016 | Galli GL, Crossley J, Elsey RM, Dzialowski EM, Shiels HA, Crossley DA 2nd (2016) Developmental plasticity of mitochondrial function in American alligators, Alligator mississippiensis. Am J Physiol Regul Integr Comp Physiol 311:R1164-72. | LEAK OXPHOS ET | N S CIV Other combinations ROX | Isolated mitochondria | Reptiles | Heart |
Galli 2021 Front Physiol | 2021 | Galli GLJ, Ruhr IM, Crossley J, Crossley DA 2nd (2021) The long-term effects of developmental hypoxia on cardiac mitochondrial function in snapping turtles. Front Physiol 12:689684. doi: 10.3389/fphys.2021.689684 | LEAK OXPHOS ET | N S CIV NS ROX | Isolated mitochondria | Reptiles | Heart |
Gam 2018 Acta Diabetol | 2018 | Gam CMBF, Mortensen OH, Larsen LH, Poulsen SS, Qvortrup K, Mathiesen ER, Damm P, Quistorff B (2018) Diabetes, myometrium, and mitochondria in pregnant women at term. Acta Diabetol 55:999-1010. | LEAK OXPHOS | F N S NS | Isolated mitochondria | Human | Genital |
Garcia 2020 Mol Hum Reprod | 2020 | Garcia BM, Machado TS, Carvalho KF, Nolasco P, Nociti RP, Del Collado M, Capo Bianco MJD, Grejo MP, Neto JDA, Sugiyama FHC, Tostes K, Pandey AK, Gonçalves LM, Perecin F, Meirelles FV, Ferraz JBS, Vanzela EC, Boschero AC, Guimarães FEG, Abdulkader F, Laurindo FRM, Kowaltowski AJ, Chiaratti MR (2020) Mice born to females with oocyte-specific deletion of mitofusin 2 have increased weight gain and impaired glucose homeostasis. Mol Hum Reprod 26:938-52. | LEAK OXPHOS ET | S | Isolated mitochondria | Mouse | Liver |
Garcia-Corzo 2013 Hum Mol Genet | 2013 | García-Corzo L, Luna-Sánchez M, Doerrier C, García JA, Guarás A, Acín-Pérez R, Bullejos-Peregrín J, López A, Escames G, Enríquez JA, Acuña-Castroviejo D, López LC (2013) Dysfunctional Coq9 protein causes predominant encephalomyopathy associated with CoQ deficiency. Hum Mol Genet 22:1233-48. | OXPHOS | N S | Isolated mitochondria | Mouse | Heart Skeletal muscle Nervous system Kidney |
Garcia-Corzo 2014 Thesis | 2014 | García-Corzo L (2014) Fisiopatologia de la deficiencia en CoQ: evaluacion de terapias con la mitocondria como diana terapeutica. Doctoral Thesis p182. | LEAK OXPHOS | N S | Isolated mitochondria | Mouse | Heart Skeletal muscle Nervous system Kidney |
Garcia-Poyatos 2024 Dev Cell | 2024 | García-Poyatos C, Arora P, Calvo E, Marques IJ, Kirschke N, Galardi-Castilla M, Lembke C, Meer M, Fernández-Montes P, Ernst A, Haberthür D, Hlushchuk R, Vázquez J, Vermathen P, Enríquez JA, Mercader N (2024) Cox7a1 controls skeletal muscle physiology and heart regeneration through complex IV dimerization. Dev Cell [Epub ahead of print]. https://doi.org/10.1016/j.devcel.2024.04.012 | LEAK OXPHOS | N S CIV NS ROX | Isolated mitochondria | Zebrafish | Skeletal muscle |
Garcia-Roche 2018 Redox Biol | 2018 | García-Roche M, Casal A, Carriquiry M, Radi R, Celia Quijano C, Cassina A (2018) Respiratory analysis of coupled mitochondria in cryopreserved liver biopsies. Redox Biol 17:207-12. | LEAK OXPHOS ET | N NS ROX S | Permeabilized tissue | Rat Bovines | Liver |
Garcia-Roche 2019 PLoS One | 2019 | García-Roche M, Casal A, Mattiauda DA, Ceriani M, Jasinsky A, Mastrogiovanni M, Trostchansky A, Carriquiry M, Cassina A, Quijano C (2019) Impaired hepatic mitochondrial function during early lactation in dairy cows: Association with protein lysine acetylation. PLoS One 14:e0213780. | LEAK OXPHOS ET | N S NS ROX | Intact cells | Bovines | Liver |
Garcia-Roche 2022 J Dairy Sci | 2022 | García-Roche M, Talmón D, Cañibe G, Astessiano AL, Mendoza A, Quijano C, Cassina A, Carriquiry M (2022) Differential hepatic mitochondrial function and gluconeogenic gene expression in 2 Holstein strains in a pasture-based system. https://doi.org/10.3168/jds.2021-21358 | LEAK OXPHOS ET | N S NS ROX | Intact cells | Bovines | Liver |
Garcia-Roche 2023 PLoS One | 2023 | García-Roche M, Talmón D, Cañibe G, Astessiano AL, Mendoza A, Cassina A, Quijano C, Carriquiry M (2023) Hepatic metabolism of grazing cows of two Holstein strains under two feeding strategies with different levels of pasture inclusion. https://doi.org/10.1371/journal.pone.0290551 | LEAK OXPHOS ET | F N S NS ROX | Intact cells | Bovines | Liver |
Garcia-Roves 2013 Abstract MiP2013 | Garcia-Roves PM, Gonzalez-Franquesa A, Martinez-Navarro L, Fernandez-Ruiz R (2013) Metabolic flexibility before and after lifestyle intervention in a diet-induced type 2 diabetes animal model. Mitochondr Physiol Network 18.08. | LEAK OXPHOS ET | N S CIV NS | Permeabilized cells Permeabilized tissue Homogenate | Mouse | Skeletal muscle Nervous system Liver Islet cell;pancreas;thymus Fat | |
Garcia-Roves 2017 MiP2017 | Mitochondrial respirometry reference values from permeabilized mouse soleus muscle fibers. MitoEAGLE WG2 pilot study. Garcia-Roves_Presentation | OXPHOS ET | N S NS ROX | Permeabilized tissue | Mouse | Skeletal muscle | |
Garcia-Roves 2018 MiP2018b | Generating mitochondrial respirometry reference values from permeabilized mouse soleus muscle fibers. Working Group 2 report. Garcia-Roves_Presentation | OXPHOS ET | N S NS ROX | Permeabilized tissue | Mouse | Skeletal muscle | |
Garcia-Roves 2019 MiPschool Coimbra | Generating reference values on mitochondrial respiration in permeabilized muscle fibers. | LEAK OXPHOS ET | N S CIV NS ROX | Permeabilized tissue | Mouse | Skeletal muscle | |
Garcia-Souza 2017 MiPschool Obergurgl | Assessment of mitochondrial respiratory function in cryopreserved platelets. | ROUTINE ET | S CIV ROX | Intact cells Permeabilized cells | Human | Blood cells Platelet | |
Garcia-Souza 2018 Life Sciences Meeting 2018 Innsbruck AT | A respirometric cell viability test for peripheral-blood mononuclear cells and platelets. | LEAK ROUTINE ET | S | Intact cells | Human | Blood cells Platelet | |
Garedew 2006 Biochim Biophys Acta | Garedew A, Lemieux H, Schachner T, Blier PU, Tardif J-C, Gnaiger E (2006) High excess capacity of cytochrome c oxidase in permeabilized fibers of the mouse heart. Biochim Biophys Acta, EBEC Short Reports Suppl 14 (2006):167-8. | OXPHOS | N S NS | Permeabilized tissue Enzyme Oxidase;biochemical oxidation | Mouse | Heart | |
Gariani 2016 Hepatology | 2016 | Gariani K, Menzies KJ, Ryu D, Wegner CJ, Wang X, Ropelle ER, Moullan N, Zhang H, Perino A, Lemos V, Kim B, Park YK, Piersigilli A, Pham TX, Yang Y, Ku SC, Koo SI, Fomitchova A, Cantó C, Schoonjans K, Sauve AA, Lee JY, Auwerx J (2016) Eliciting the mitochondrial unfolded protein response via NAD+ repletion reverses fatty liver disease. Hepatology 63:1190-204. | OXPHOS | N S | Permeabilized tissue | Mouse | Liver |
Gariani 2016 J Hepatol | 2016 | Gariani K, Ryu D, Menzies KJ, Yi HS, Stein S, Zhang H, Perino A, Lemos V, Katsyuba E, Jha P, Vijgen S, Rubbia-Brandt L, Kim YK, Kim JT, Kim KS, Shong M, Schoonjans K, Auwerx J (2016) Inhibiting poly ADP-ribosylation increases fatty acid oxidation and protects against fatty liver disease. J Hepatol 66:132-41. | OXPHOS | N S NS | Permeabilized tissue | Mouse | Liver |
Garnham 2019 J Cachexia Sarcopenia Muscle | 2019 | Garnham JO, Roberts LD, Caspi T, Al-Owais MM, Bullock M, Swoboda PP, Koshy A, Gierula J, Paton MF, Cubbon RM, Kearney MT, Bowen TS, Witte KK (2019) Divergent skeletal muscle mitochondrial phenotype between male and female patients with chronic heart failure. J Cachexia Sarcopenia Muscle 11:79-88. | LEAK OXPHOS ET | N S CIV NS ROX | Permeabilized tissue | Human | Skeletal muscle |
Garnol 2014 Physiol Res | 2014 | Garnol T, Endlicher R, Kučera O, Drahota Z, Cervinková Z (2014) Impairment of mitochondrial function of rat hepatocytes by high fat diet and oxidative stress. Physiol Res 63:271-4. | LEAK OXPHOS ET | N S | Permeabilized cells Isolated mitochondria Intact cells | Rat | Liver |
Garratt 2014 Proc Natl Acad Sci U S A | 2014 | Garratt M, Pichaud N, Glaros EN, Kee AJ, Brooks RC (2014) Superoxide dismutase deficiency impairs olfactory sexual signaling and alters bioenergetic function in mice. Proc Natl Acad Sci U S A 111:8119-24. | LEAK OXPHOS ET | F N S CIV NS ROX | Permeabilized tissue | Mouse | Liver |
Garrido-Maraver 2019 Cell Death Dis | 2019 | Garrido-Maraver J, Celardo I, Costa AC, Lehmann S, Loh SHY, Martins LM (2019) Enhancing folic acid metabolism suppresses defects associated with loss of Drosophila mitofusin. Cell Death Dis 10:288. | OXPHOS ET | N S | Permeabilized tissue | Drosophila | |
Gasmi 2021 Arch Toxicol | 2021 | Gasmi A, Peana M, Arshad M, Butnariu M, Menzel A, Bjørklund G (2021) Krebs cycle: activators, inhibitors and their roles in the modulation of carcinogenesis. Arch Toxicol 95:1161-78. https://doi.org/10.1007/s00204-021-02974-9 | S | ||||
Gautam 2023 Neurobiol Dis | 2023 | Gautam M, Genç B, Helmold B, Ahrens A, Kuka J, Makrecka-Kuka M, Günay A, Koçak N, Aguilar-Wickings IR, Keefe D, Zheng G, Swaminathan S, Redmon M, Zariwala HA, Özdinler PH (2023) SBT-272 improves TDP-43 pathology in ALS upper motor neurons by modulating mitochondrial integrity, motility, and function. https://doi.org/10.1016/j.nbd.2023.106022 | LEAK OXPHOS | N S CIV NS ROX | Permeabilized tissue Homogenate | Rat | Heart Nervous system |
Gehrig 2016 Orphanet J Rare Dis | 2016 | Gehrig SM, Mihaylova V, Frese S, Mueller SM, Ligon-Auer M, Spengler CM, Petersen JA, Lundby C, Jung HH (2016) Altered skeletal muscle (mitochondrial) properties in patients with mitochondrial DNA single deletion myopath. Orphanet J Rare Dis 11:105. | LEAK OXPHOS | F N S CIV NS Other combinations ROX | Permeabilized tissue | Human | Skeletal muscle |
Gellerich 2010 Biochim Biophys Acta | 2010 | Gellerich FN, Gizatullina Z, Trumbeckaite S, Nguyen HP, Pallas T, Arandarcikaite O, Vielhaber S, Seppet E, Striggow F (2010) The regulation of OXPHOS by extramitochondrial calcium. Biochim Biophys Acta 1797:1018-27. | LEAK OXPHOS | N S | Isolated mitochondria | Rat | Nervous system |
Gerber 2017 Brain | 2017 | Gerber S, Charif M, Chevrollier A, Chaumette T, Angebault C, Kane MS, Paris A, Alban J, Quiles M, Delettre C, Bonneau D, Procaccio V, Amati-Bonneau P, Reynier P, Leruez S, Calmon R, Boddaert N, Funalot B, Rio M, Bouccara D, Meunier I, Sesaki H, Kaplan J, Hamel CP, Rozet JM, Lenaers G (2017) Mutations in DNM1L, as in OPA1, result indominant optic atrophy despite opposite effects on mitochondrial fusion and fission. Brain 140:2586-96. | LEAK OXPHOS ET | N S NS | Permeabilized cells | Human | Endothelial;epithelial;mesothelial cell Fibroblast |
Geyer 1951 J Biol Chem | 1951 | Geyer RP, Cunningham M, Bendergast J (1951) Inhibition studies on radioactive fatty acid metabolism. J Biol Chem 188:185-91 | F S | Rat | Liver | ||
Gifford 2017 J Appl Physiol (1985) | 2017 | Gifford JR, Trinity JD, Kwon OS, Layec G, Garten RS, Park SY, Nelson AD, Richardson RS (2017) Altered skeletal muscle mitochondrial phenotype in COPD: disease versus disuse. J Appl Physiol (1985) 124:1045-53. | OXPHOS | N S NS | Permeabilized tissue | Human | Skeletal muscle |