Talk:Bioblast alert 2015

Bioblast alert - in preparation

Bioblast alert 2014(01): 2014-##-##

• MiP2014 - Joint IUBMB/MiP Symposium on Mitochondrial Physiology - a Point/Counterpoint Meeting: This MiPconference will cover genotype/phenotype and structure/function relationships; focus on optimization of experimental protocols, quality control and normalization of mt-function; compare mt-preparations, experimental platforms and tissue/species specific models; extend networking of national/international organizations.
• MitoGlobal_Events_2014: Check out this year’s emerging list of world-wide mitochondrial events. Let us know about additional mt-events to be listed. In the spirit of positive feedback, please refer on your website to the Mitochondrial Global Network.
• MitoPedia Glossary: Malate as substrate in respirometry – inhibition at higher concentrations. The type and concentration of respiratory substrates is important for the design of substrate-uncoupler-inhibitor titration (SUIT) protocols. 0.5 mM malate saturates CI linked respiration in combination with pyruvate and/or glutamate, whereas 2 mM malate inhibits CII linked (succinate+rotenone) and CI+II linked respiration, as shown in mouse heart (collaboration with the group of Sameh Ali), mouse brain homogenate, beef heart mitochondria, human permeabilized skeletal muscle fibres, dog permeabilized skeletal muscle fibers (IOC84), brine shrimp embryo (Artemia franciscana) mitochondria (collaboration with Steve Hand), fish liver and heart homogenates (post IOC80 training course).

New topics

• MitoPedia Glossary: Electron transfer system versus electron transport chain

Topics not yet covered

• MitoGlobal: Consortia and research centres with a focus on mitochondrial research and medicine are listed as MitoGlobal_Centres.
• Topic: O2-kinetics
• Preparation: Homogenate/isolated mitochondria; intact/permeabilized cells; permeabilized fibre/in vivo
• Protocols

Bioblast alert - concept

Here is a brief summary on the concept of Bioblast alert. Some of the following topics (not more than four per alert) will be selected for a Bioblast alert.

High-resolution terminology

• high-resolution terminology - matching measurement at high-resolution. Term of the week: Basal respiration
• Define – Measure: terminology and experimental approach
• Define – Clarify: consider discrepancies, resolve problems

MiPevents

• Conferences and Workshops

Bioblast News

• What is new or updated on the website: Lists (chemicals, protocols, scientific service, ..). A term may be selected (perhaps related to the publication), updated, discussed in our group, and then presented in the Bioblast alert. As Bioblast is updated, the updated ‘article’ can be added to the prepared points for a future Bioblast alert.
• Projects in mitochondrial science (COST HypoxiaNet; Framework programs; ..)
• Links on the Bioblast website; networking in mitochondrial science, presentation of: MIG List, Mitochondrion journal and website; Mitochondrial Societies

Not included in Bioblast alert

MiPNet O2k-Publications

A Bioblast editor may select an O2k-Publication (or a small number of related publications), particularly from a MiPNet Reference Laboratory, may get in contact with the particular reference lab, update info on the lab, and ‘present’ the lab on the start page of the Bioblast website.

MiPNet Laboratories of the World

Contact the MiPNet laboratories: show link on the wiki, ask for updates on group, references, website, perhaps major projects (HypoxiaNet), perhaps add pictures, perhaps keywords/short description. Circular: link to presented lab / special occasion (e.g. publication; conference presentation; new member; PhD thesis, ..

Popular Bioblast page

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