Coupling-control protocol: Difference between revisions

Revision as of 12:38, 31 May 2011

high-resolution terminology - matching measurements at high-resolution

Coupling-control protocol

Description

[[Description::A phosphorylation control protocol induces different coupling control states at constant substrate supply. In intact cells, the PCP can be applied by using membrane-permeable inhibitors of the phosphorylation system (e.g. oligomycin) and uncouplers (e.g. FCCP). Coupling control states in intact cells include R, L, E; LEAK, ROUTINE, and ETS. Coupling control states in isolated mitochondria, permeabilized cells or homogenates include L, P, E; LEAK, OXPHOS, and ETS.]]

Abbreviation: PCP

Reference: [[Info::Pesta_2011_Protocols]]

MitoPedia topics: Respiratory state

Labels:

Regulation: Respiration; OXPHOS; ETS Capacity

@@ Line 2: / Line 2: @@
 |abbr=PCP
 |description=A '''phosphorylation control protocol''' induces different [[coupling control state]]s at constant substrate supply. In [[intact cell]]s, the PCP can be applied by using membrane-permeable inhibitors of the [[phosphorylation system]] (e.g. [[oligomycin]]) and [[uncoupler]]s (e.g. [[FCCP]]). Coupling control states in intact cells include ''R'', ''L'', ''E''; [[LEAK]], [[ROUTINE]], and [[ETS]]. Coupling control states in isolated mitochondria, permeabilized cells or homogenates include ''L'', ''P'', ''E''; LEAK, [[OXPHOS]], and ETS.
-|info=Pesta_2011_Protocols
+|info=[[Pesta_2011_Protocols]]
 |type=Respiration
 }}