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COST Action CA15203 (2016-2021): MitoEAGLE
Evolution-Age-Gender-Lifestyle-Environment: mitochondrial fitness mapping
Wiesner Rudolf J
MitoPedia topics: EAGLE
Name | Wiesner Rudolf J, Prof. Dr. |
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Institution | Institute for Vegetative Physiology,
Universtiy of Cologne, DE |
Address | Robert-Koch-Str. 39, 50931 |
City | Cologne |
State/Province | |
Country | Germany |
[email protected] | |
Weblink | |
O2k-Network Lab |
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Publications
Published | Reference | |
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BEC 2020.1 doi10.26124bec2020-0001.v1 | 2020 | Gnaiger E et al โ MitoEAGLE Task Group (2020) Mitochondrial physiology. Bioenerg Commun 2020.1. https://doi.org/10.26124/bec:2020-0001.v1 |
Schommers 2017 Mol Metab | 2017 | Schommers P, Thurau A, Bultmann-Mellin I, Guschlbauer M, Klatt AR, Rozman J, Klingenspor M, de Angelis MH, Alber J, Grรผndemann D, Sterner-Kock A, Wiesner RJ (2017) Metformin causes a futile intestinal-hepatic cycle which increases energy expenditure and slows down development of a type 2 diabetes-like state. Mol Metab 6:737-47. |
Franko 2016 Diabetes | 2016 | Franko A, Huypens P, Neschen S, Irmler M, Rozman J, Rathkolb B, Neff F, Prehn C, Dubois G, Baumann M, Massinger R, Gradinger D, Przemeck GK, Repp B, Aichler M, Feuchtinger A, Schommers P, Stรถhr O, Sanchez-Lasheras C, Adamski J, Peter A, Prokisch H, Beckers J, Walch AK, Fuchs H, Wolf E, Schubert M, Wiesner RJ, Hrabฤ de Angelis M (2016) Bezafibrate improves insulin sensitivity and metabolic flexibility in STZ-treated diabetic mice. Diabetes 65:2540-52. |
Szczepanowska 2016 EMBO J | 2016 | Szczepanowska K, Maiti P, Kukat A, Hofsetz E, Nolte H, Senft K, Becker C, Ruzzenente B, Hornig-Do HT, Wibom R, Wiesner RJ, Krรผger M, Trifunovic A (2016) CLPP coordinates mitoribosomal assembly through the regulation of ERAL1 levels. EMBO J 35:2566-83. |
Franko 2012 J Mol Med | 2012 | Franko A, von Kleist-Retzow JC, Bรถse M, Sanchez-Lasheras C, Brodesser S, Krut O, Kunz WS, Wiedermann D, Hรถhn M, Stรถhr O, Moll L, Freude S, Krone W, Schubert M, Wiesner RJ (2012) Complete failure of insulin-transmitted signaling, but not obesity-induced insulin resistance, impairs respiratory chain function in muscle. J Mol Med 90:1145-60. |
Freyer 2012 Nat Genet | 2012 | Freyer C, Cree LM, Mourier A, Stewart JB, Koolmeister C, Milenkovic D, Wai T, Floros VI, Hagstrรถm E, Chatzidaki EE, Wiesner RJ, Samuels DC, Larsson NG, Chinnery PF (2012) Variation in germline mtDNA heteroplasmy is determined prenatally but modified during subsequent transmission. Nat Genet 44:1282-5. |
Schultz 2000 J Bioenerg Biomembr | 2000 | Schultz J, Wiesner RJ (2000) Proliferation of mitochondria in chronically stimulated rabbit skeletal muscle--transcription of mitochondrial genes and copy number of mitochondrial DNA. J Bioenerg Biomembr 32:627-34. |
Wiesner 1988 Biochim Biophys Acta | 1988 | Wiesner RJ, Kreutzer U, Rรถsen P, Grieshaber MK (1988) Subcellular distribution of malate-aspartate cycle intermediates during normoxia and anoxia in the heart. Biochim Biophys Acta 936:114-23. |
Abstracts
Published | Reference | |
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Kimoloi 2019 MiPschool Coimbra | 2019 | Mitochondrial DNA (mtDNA) maintenance defects impairs muscle stem cells regenerative efficiency. |
Wiesner 2018 MiPschool Tromso E1 | 2018 | Aging-related accumulation of mitochondrial DNA deletions in skeletal muscle occurs preferentially in Type IIb fibers โ high mitophagic flux protects Type I fibers. |