From Bioblast
US PA Pittsburgh Goetzman ES
| O2k-Network Lab | Children's Hospital of Pittsburgh |
|---|---|
| Address | 4401 Penn Ave, 15224 |
| City | Pittsburgh |
| State/Prov | Pennsylvania (PA) |
| Country | USA |
| Weblink | |
| Contact | Goetzman Eric S |
| Team | Bharathi Sivakama S, Seminotti Bianca, Uppala Radha, Vockley Jerry, Zhang Yuxun |
| Team previous | Votyakova Tatyana V, Zeak Jennifer |
| Status | O2k 2008 – |
| Oroboros Events | IOC104, IOC56, IOC41 |
| Topics | fatty acid oxidation, post-translational modifications, sirtuins, lung metabolism, cancer metabolism |
O2k-Publications
| Published | Reference | |
|---|---|---|
| Airik 2023 Antioxidants (Basel) | 2023 | Airik M, Arbore H, Childs E, Huynh AB, Phua YL, Chen CW, Aird K, Bharathi S, Zhang B, Conlon P, Kmoch S, Kidd K, Bleyer AJ, Vockley J, Goetzman E, Wipf P, Airik R (2023) Mitochondrial ROS triggers KIN pathogenesis in FAN1-deficient kidneys. https://doi.org/10.3390/antiox12040900 |
| Dobrowolski 2022 Mol Genet Metab | 2022 | Dobrowolski SF, Phua YL, Sudano C, Spridik K, Zinn PO, Wang Y, Bharathi S, Vockley J, Goetzman E (2022) Comparative metabolomics in the Pahenu2 classical PKU mouse identifies cerebral energy pathway disruption and oxidative stress. https://doi.org/10.1016/j.ymgme.2022.03.004 |
| Dobrowolski 2021 Mol Genet Metab | 2021 | Dobrowolski SF, Sudano C, Phua YL, Tourkova IL, Spridik K, Goetzman ES, Vockley J, Blair HC (2021) Mesenchymal stem cell energy deficit and oxidative stress contribute to osteopenia in the Pahenu2 classical PKU mouse. Mol Genet Metab 132:173-79. |
| Pereyra 2021 J Lipid Res | 2021 | Pereyra AS, Harris KL, Soepriatna AH, Waterbury QA, Bharathi SS, Zhang Y, Fisher-Wellman KH, Goergen CJ, Goetzman ES, Ellis JM (2021) Octanoate is differentially metabolized in liver and muscle and fails to rescue cardiomyopathy in CPT2 deficiency. J Lipid Res 62:100069. |
| Zhang 2019 Redox Biol | 2019 | Zhang Y, Bharathi SS, Beck ME, Goetzman ES (2019) The fatty acid oxidation enzyme long-chain acyl-CoA dehydrogenase can be a source of mitochondrial hydrogen peroxide. Redox Biol 26:101253. |
| Wang H 2019 J Biol Chem | 2019 | Wang H, Lu J, Kulkarni S, Zhang W, Gorka JE, Mandel JA, Goetzman ES, Prochownik EV (2019) Metabolic and oncogenic adaptations to pyruvate dehydrogenase inactivation in fibroblasts. J Biol Chem 294:5466-86. |
| Uppala 2017 Biochem Biophys Res Commun | 2017 | Uppala R, Dudiak B, Beck ME, Bharathi SS, Zhang Y, Stolz DB, Goetzman ES (2017) Aspirin increases mitochondrial fatty acid oxidation. Biochem Biophys Res Commun 482:346-51. |
| Zhang 2017 J Biol Chem | 2017 | Zhang Y, Bharathi SS, Rardin MJ, Lu J, Maringer KV, Sims-Lucas S, Prochownik EV, Gibson BW, Goetzman ES (2017) Lysine desuccinylase SIRT5 binds to cardiolipin and regulates the electron transport chain. J Biol Chem 292:10239-49. |
| Jackson 2017 Cancer Res | 2017 | Jackson LE, Kulkarni S, Wang H, Lu J, Dolezal JM, Bharathi SS, Ranganathan S, Patel MS, Deshpande R, Alencastro F, Wendell SG, Goetzman ES, Duncan AW, Prochownik EV (2017) Genetic dissociation of glycolysis and the TCA cycle affects neither normal nor neoplastic proliferation. Cancer Res 77:5795-807. |
| Dolezal 2017 J Biol Chem | 2017 | Dolezal JM, Wang H, Kulkarni S, Jackson L, Lu J, Ranganathan S, Goetzman ES, Bharathi SS, Beezhold K, Byersdorfer CA, Prochownik EV (2017) Sequential adaptive changes in a c-Myc-driven model of hepatocellular carcinoma. J Biol Chem 292:10068-86. |
| Wang 2016 J Biol Chem | 2016 | Wang H, Lu J, Edmunds LR, Kulkarni S, Dolezal J, Tao J, Ranganathan S, Jackson L, Fromherz M, Stolz DB, Uppala R, Bharathi S, Monga SP, Goetzman ES, Prochownik EV (2016) Coordinated activities of multiple Myc-dependent and Myc-independent biosynthetic pathways in Hepatoblastoma. J Biol Chem 291:26241-51. |
| Selivanov 2012 PLoS Comput Biol | 2012 | Selivanov VA, Cascante M, Friedman M, Schumaker MF, Trucco M, Votyakova TV (2012) Multistationary and oscillatory modes of free radicals generation by the mitochondrial respiratory chain revealed by a bifurcation analysis. PLoS Comput Biol 8(9):e1002700. doi: 10.1371/journal.pcbi.1002700. |
| Selivanov 2011 PLoS Comput Biol | 2011 | Selivanov VA, Votyakova TV, Pivtoraiko VN, Zeak J, Sukhomlin T, Trucco M, Roca J, Cascante M (2011) Reactive oxygen species production by forward and reverse electron fluxes in the mitochondrial respiratory chain. PLoS Comput Biol 7(3):e1001115. doi: 10.1371/journal.pcbi.1001115. |
O2k-Abstracts
update please
