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• 115th International Titisee Conferences Titisee DE  + (115th ITC: Evolutionary mitochondrial biology: molecular, biochemical, and metabolic diversity, Titisee, Germany.)
• 11th Annual Congress of Cardiology 2019 Suzhou CN  + (11th Annual Congress of Cardiology, Suzhou, China, 2019)
• MiP2015  + (11th Conference on Mitochondrial Physiology, 2015 Sep 07-11, Luční Bouda, Czech Republic.)
• Targeting Mitochondria World Congress 2020 Virtual  + (11th World Congress on Targeting Mitochond … 11th World Congress on Targeting Mitochondria, Virtual, 2020 </br></br></br>== General information == </br>:::: After a long and thorough discussion among the scientific and organizing committees, we have decided to organize our 11th Conference of Targeting Mitochondria, on October 29-30, 2020 as an ONLY Virtual Congress.</br></br>== Programme ==</br>:::: [https://targeting-mitochondria.com/preliminary-program here]</br></br>== Speakers == </br>:::: List of speakers can be found [https://targeting-mitochondria.com/speakers here]</br></br>== Registration ==</br>:::: [https://targeting-mitochondria.com/registration Registration and more information]tration Registration and more information])
• 11th ÖGMBT Annual Meeting 2019 Salzburg AT  + (11th ÖGMBT Annual Meeting - Inside the world of biomolecules, Salzburg, Austria, 2019)
• ASMRM 2015 Hangzhou CN  + (12^th Conference of the Asian Society of Mitochondrial Research and Medicine - [http://www.ig.zju.edu.cn/ASMRM/EN/ ASMRM 2015], Hangzhou CN)
• 12th International Conference on Obesity and Eating Disorders 2023 Vienna AT  + (12th International Conference on Obesity a … 12th International Conference on Obesity and Eating Disorders, Vienna, Austria, 2023 </br></br>== General Information == </br>:::: The theme of the conference is "New Emerging Challenges in Obesity and their Prevention"</br></br>== Venue ==</br>:::: [https://obesity.euroscicon.com/ How to get there]</br></br>== Program ==</br>:::: Program available [https://obesity.euroscicon.com/program-schedule here]</br></br>== Organizers ==</br>:::: The list of organizers can be found [https://obesity.euroscicon.com/organizing-committee here]</br></br>== Registration ==</br>:::: [https://obesity.euroscicon.com/registration Registration and more information]</br>:::: Early registration deadline: 203-01-27</br>:::: Late registration deadline: 2023-04-10::: Late registration deadline: 2023-04-10)
• IPC2021 Puerto Varas CL  + (12th International Phycological Congress - … 12th International Phycological Congress - IPC2021, Puerte Varas, Chile, 2021 </br></br>== Venue == </br>::::[https://ipc2021.com/logistic-information/ Venue and how to get there]</br></br>== Programme ==</br>:::: [https://ipc2021.com/scientific-program/ here]</br></br>== Speakers == </br>:::: List of speakers can be found [https://ipc2021.com/invited-speakers/ here]</br></br>== Organizers ==</br>:::: The list of organizers can be found [https://ipc2021.com/local-organizing-committee-scientific-committee/ here]</br></br>== Registration ==</br>:::: [https://ipc2021.com/registration-and-registration-fees-submission-of-abstracts/ Registration and more information]tracts/ Registration and more information])
• 12th ÖGMBT Annual Meeting 2020 Virtual Event  + (12th ÖGMBT Annual Meeting - Biomolecules in/for 21st century, Virtual Event, 2020 '''''- Conference will be held via a virtual interactive meeting. Oroboros Instruments will be present with a virtual booth.''''')
• Life Sciences Meeting 2018 Innsbruck AT  + (13th Life Sciences Meeting, Innsbruck, Aus … 13th Life Sciences Meeting, Innsbruck, Austria, 2018 </br></br>__TOC__</br></br>== General information== </br>:::: The coming meeting will take place on the 5th and 6th of April, 2018 in the CCB (Center for Chemistry and Biomedicine) and offers all participants and young researchers the possibility to present their research work in the form of a posters or a short talk. At the end of the event the best presentation will be selected by a professional jury consisting of professors of the Medical University of Innsbruck and the winners will be awarded with a prize. The closure of the meeting will be made by the famous scientist Prof. Jannie Cracking of the Netherland Cancer Institute. The Medical University of Innsbruck is looking forward to welcoming Prof. Cracking as a „Key Note Speaker“. </br></br></br>== Venue == </br>:::: Center for Chemistry and Biomedicine (CCB)</br>:::: Innrain 80, 6020 Innsbruck</br>:::: [http://biocenter.i-med.ac.at/ Location]</br></br>== Organizers ==</br>:::: Medical University of Innsbruck</br></br>==Oroboros presentation ==</br>:::: TALK: Marie Skłodowska-Curie Project '''[[TRANSMIT]]''' [[Bastos Sant'Anna Silva AC|Bastos Sant'Anna Silva Ana Carolina]]: [[Bastos Sant'Anna Silva AC 2018 Life Sciences Meeting 2018 Innsbruck AT|Effect of cell-permeable succinate and malonate prodrugs on mitochondrial respiration in prostate cancer cells]]</br>:::: POSTER: Marie Skłodowska-Curie Project '''[[TRACT]]''' [[Chang Shao-Chiang]]: [[Chang 2018 Life Sciences Meeting 2018 Innsbruck AT|pH dependence of mitochondrial respiration and H₂O₂ production in oral cancer cells – a pilot study.]]</br>:::: POSTER: K-Regio Project '''[[K-Regio_MitoFit|MitoFit]]''' [[Garcia-Souza LF|Garcia-Souza Luiz]]: [[Garcia-Souza 2018 Life Sciences Meeting 2018 Innsbruck AT|A respirometric cell viability test for peripheral-blood mononuclear cells and platelets]]-Souza 2018 Life Sciences Meeting 2018 Innsbruck AT|A respirometric cell viability test for peripheral-blood mononuclear cells and platelets]])
• 13th Targeting Mitochondria Congress 2022 Berlin DE  + (13th Targeting Mitochondria Congress, Berlin, 2022)
• EBSA2021 Vienna AT  + (13th congress of EBSA, Vienna, Austria, 2021)
• 13th ÖGMBT Annual Meeting 2021 Innsbruck AT  + (13th ÖGMBT Annual Meeting, Virtual, 2021)
• FAOBMB 2015 Hyderabad IN  + (14^th Congress of the Federation of Asian and Oceanian Biochemists and Molecular Biologists (FAOBMB) - [http://www.ccmb.res.in/faobmb2015/ FAOBMB 2015], Hyderabad IN)
• EBSA 2023 Stockholm SE  + (14th congress of EBSA, Stockholm, Sweden, 2023)
• The Power of Metabolism Linking energy supply and demand with contractile function 2017 Weimar DE  + (15th Annual Meeting: The Power of Metabolism - Linking energy supply and demand with contractile function, Weimar,)
• ASMRM 2018 Busan KR  + (15th Conference of the Asian Society of Mitochondrial Research and Medicine, Busan, South Korea, 2018.)
• 16th Chinese Biophysics Congress 2018 Chengdu CH  + (16th Chinese Biophysics Congress - Biophysics and human health , Chengdu, China, 2018)
• J-mit 2017 Kyoto JP  + (17^th Annual Conference of Janpanese Society of Mitochondrial Research and Medicine, Kyoto, Japan)
• 17th Chinese Biophysics Congress 2019 Tianjin CN  + (17th Chinese Biophysics Congress, Tianjin , China, 2019)
• 17th International Biochemistry of Exercise Conference 2018 Beijing CN  + (17th International Biochemistry of Exercise Conference, Beijing, China, 2018)
• The 18th Annual Meeting of the Japan Mitochondrial Association 2018 Kurume JP  + (18th Annual Meeting of the Japan Mitochondrial Association, Kurume, 2018)
• KSMRM2014  + (19^th Annual Scientific Meeting of KSMRM , Seoul, Republic of Korea; [http://2014.ksmrm.org/congress/invitation.php KSMRM2014])
• SHVM 2022 Seoul KR  + (19th Annual Meeting of the Society for Heart and Vascular Metabolism (SHVM), Seoul , South Korea, 2022)
• 19th Beijing Conference and Exhibition on Instrumental Analysis 2021 Beijing CN  + (19th Beijing Conference and Exhibition on Instrumental Analysis, Beijing, China, 2021)

• 19th Chinese Biophysics congress 2021 Anhui CN  + (19th Chinese Biophysics congress, Anhui Province, China, 2021)

• ESP2021 Salzburg AT  + (19th Congress of the European Society for … 19th Congress of the European Society for Photobiology - ESP2021, Salzburg, Austria, 2021 </br></br>== Venue == </br>:::: Faculty of Natural Sciences (NAWI) of the Paris Lodron University Salzburg (PLUS)</br>:::: Venue address: Hellbrunnerstrasse 34, 5020 Salzburg, Austria.</br>:::: [http://salzburg2021.photobiology.eu/congress-venue more information]</br></br>== Program ==</br>:::: [http://salzburg2021.photobiology.eu/ here]</br></br>== Speakers == </br>:::: List of speakers can be found [http://salzburg2021.photobiology.eu/ here]</br></br>== Organizers ==</br>:::: The list of organizers can be found [http://salzburg2021.photobiology.eu/organizing-committee here]</br></br>== Registration ==</br>:::: [http://salzburg2021.photobiology.eu/ Registration and more information]ogy.eu/ Registration and more information])
• Chlamy 2021 Ile des Embiez FR  + (19th International Conference on the Cell and Molecular Biology of Chlamydomonas, Ile des Embiez, France, 2021)
• FEBS 2023 Luso PT  + (1^st 1st FEBS Workshop “Redox Medicine Workshop, Luso, Portugal, 2023)
• MiPschool Schroecken AT 2007  + (1^st MiP''summer school'' on Mitochondrial Respiratory Physiology, 2007 July 12-18, Schroecken, AT.)
• 1st Myocardial Function Symposium 2020 Graz AT  + (1st Myocardial Function Symposium: “Targets in cardiometabolic disease”, Graz, Austria, 2020)
• SHVM 2021 Virtual  + (1st virtual meeting of the Society for Heart and Vascular Metabolism (SHVM), Virtual, 2021)
• Goncalves 2017 J Cell Commun Signal  + (1α,25-Dihydroxyvitamin D<sub>3</s … 1α,25-Dihydroxyvitamin D₃ (1,25-D₃) is critical for the maintenance of normal male reproduction since reduced fertility is observed in vitamin D-deficient rats. Gamma-glutamyl transpeptidase (GGT) is a membrane-bound enzyme that is localized on Sertoli cells and catalyses the transfer of the gamma-glutamyl residues to an amino acid or peptide acceptor. Sertoli cells are also responsible for providing nutrients, as lactate, to the development of germ cells. The aim of this study was to investigate the effect and the mechanism of action of 1,25-D₃ on GGT on Sertoli cell functions from 30-day-old immature rat testis. Results demonstrated that 1,25-D₃ stimulates GGT activity at Sertoli cells plasma membrane through a PKA-dependent mechanism of action, which was not dependent of active ''de novo'' protein synthesis. The hormone increases glucose uptake, as well as lactate production and release by Sertoli cells without altering the reactive oxygen species (ROS) generation. In addition, 1,25-D₃ did not change reduced glutathione (GSH) amount or oxygen consumption, and diminished Sertoli cell death. These findings demonstrate that 1,25-D₃ stimulatory effect on GGT activity, glucose uptake, LDH activity and lactate production seem to be an important contribution of Sertoli cells for germ cells nutrition and for a full and active ongoing spermatogenesis.mportant contribution of Sertoli cells for germ cells nutrition and for a full and active ongoing spermatogenesis.)
• Royall 1993 Arch Biochem Biophys  + (2',7'-Dichlorofluorescein and dihydrorhoda … 2',7'-Dichlorofluorescein and dihydrorhodamine 123 were evaluated as probes for detecting changes in intracellular H2O2 in cultured endothelial cells. Stable intracellular levels of these probes were established within 15 min of exposure to the probe in culture medium. With continued presence of the probe in the medium, intracellular levels were unchanged for 1 h. However, if medium without the probes was used after intracellular loading had occurred, there was a greater than 90% loss of intracellular dichlorofluorescin, dichlorofluorescein, and dihydrorhodamine 123 while intracellular rhodamine 123 decreased by only 15%. Exposure of endothelial cells to exogenous 100 microM H2O2 for 1 h increased intracellular rhodamine 123 by 83%, but there was a reproducible decrease of 53% in intracellular dichlorofluorescein. Exposure to 0.05 mM BCNU plus 10 mM aminotriazole for 2 h increased intracellular rhodamine 123 by 111%. In vitro studies of dihydrorhodamine 123 oxidation were similar to previous reports of dichlorofluorescin oxidation. Oxidation of dihydrorhodamine 123 does not occur with H2O2 alone, but is mediated by a variety of secondary H2O2-dependent intracellular reactions including H2O2-cytochrome c and H2O2-Fe2+. Our results suggest that detection of increased oxidation of these probes in endothelial cells is most useful as a marker of a change in general cellular oxidant production.ge in general cellular oxidant production.)
• Lardy 1953 J Biol Chem  + (2,4-Dinitrophenol greatly enhanced the … 2,4-Dinitrophenol greatly enhanced the liberation of inorganic phosphate from ATP by the nuclear and mitochondrial fraction of rat liver. </br>The microsomal and supernatant fractions did not exhibit this effect. </br></br>With mitochondria (Mw) the rate of phosphate liberation was proportional to the DNP concentration up to 6 X 10-5 M In the presence of excess DNP the rate was proportional to the quantity of Mw nd to time. </br></br>With both fresh and preaged Mw, the response to DNP was much greater </br>in mediums containing salt (either NaCl or KCl) than in isotonic sucrose. Magnesium salts in appreciable concentrations depressed the response of fresh Mw to DNP, but enhanced the response in preaged Mw. Calcium salts, which activate ATP hydrolysis by fresh Mw in the absence of DNP, also depressed the effect of DNP on phosphate liberation. Magnesium salts enhanced phosphate liberation by preaged Mw both in the presence and absence of DNP. Calcium was virtually without effect in preaged Mw. </br></br>Oxalacetate enhanced phosphate liberation from ATP by fresh Mw. This dicarboxylic acid as well as succinate and L-malate depressed the </br>effect of DNP on phosphate liberation. Fatty acids also depressed the </br>effect of DNP. Caprylate enhanced phosphate liberation, probably be- </br>cause of its surface activity. </br></br>The thiol inhibitor, p-chloromercuribenzoate, strongly depressed the effect of DNP; iodoacetate and o-iodosobenzoate did not.</br></br>''Continued in Free Text''ate did not. ''Continued in Free Text'')
• Freitas-Correa 2013 Stem Cell Res  + (2,4-Dinitrophenol (DNP) is a neuroprotecti … 2,4-Dinitrophenol (DNP) is a neuroprotective compound previously shown to promote neuronal differentiation in a neuroblastoma cell line and neurite outgrowth in primary neurons. Here, we tested the hypothesis that DNP could induce neurogenesis in embryonic stem cells (ESCs). Murine ESCs, grown as embryoid bodies (EBs), were exposed to 20μM DNP (or vehicle) for 4days. Significant increases in the proportion of nestin- and β-tubulin III-positive cells were detected after EB exposure to DNP, accompanied by enhanced glial fibrillary acidic protein (GFAP), phosphorylated extracellular signal-regulated kinase (p-ERK) and ATP-linked oxygen consumption, thought to mediate DNP-induced neural differentiation. DNP further protected ESCs from cell death, as indicated by reduced caspase-3 positive cells, and increased proliferation. Cell migration from EBs was significantly higher in DNP-treated EBs, and migrating cells were positive for nestin, ß-tubulin III and MAP2, similar to that observed with retinoic acid (RA)-treated EBs. Compared to RA, however, DNP exerted a marked neuritogenic effect on differentiating ESCs, increasing the average length and number of neurites per cell. Results establish that DNP induces neural differentiation of ESCs, accompanied by cell proliferation, migration and neuritogenesis, suggesting that DNP may be a novel tool to induce neurogenesis in embryonic stem cells.duce neurogenesis in embryonic stem cells.)
• Sebollela 2010 Neurotox Res  + (2,4-Dinitrophenol (DNP) is classically kno … 2,4-Dinitrophenol (DNP) is classically known as a mitochondrial uncoupler and, at high concentrations, is toxic to a variety of cells. However, it has recently been shown that, at subtoxic concentrations, DNP protects neurons against a variety of insults and promotes neuronal differentiation and neuritogenesis. The molecular and cellular mechanisms underlying the beneficial neuroactive properties of DNP are still largely unknown. We have now used DNA microarray analysis to investigate changes in gene expression in rat hippocampal neurons in culture treated with low micromolar concentrations of DNP. Under conditions that did not affect neuronal viability, high-energy phosphate levels or mitochondrial oxygen consumption, DNP induced up-regulation of 275 genes and down-regulation of 231 genes. Significantly, several up-regulated genes were linked to intracellular cAMP signaling, known to be involved in neurite outgrowth, synaptic plasticity, and neuronal survival. Differential expression of specific genes was validated by quantitative RT-PCR using independent samples. Results shed light on molecular mechanisms underlying neuroprotection by DNP and point to possible targets for development of novel therapeutics for neurodegenerative disorders.rapeutics for neurodegenerative disorders.)
• 2014 Mitochondrial Disease Clinical Conference  + (2014 Mitochondrial Disease Clinical Conference, Los Angeles, Ca US; [http://www.mitoaction.org/laconference 2014 Mitochondrial Disease Clinical Conference])
• 2015 Spring PaduaMuscleDays  + (2015 Spring PaduaMuscleDays: Translational Myology in Aging and Neuromuscular Disorders, Padova, IT; [http://www.pagepressjournals.org/index.php/bam/announcement/view/176 2015 Spring PaduaMuscleDays].)
• 2016 Spring PaduaMuscleDays Padua IT  + (2016 Spring PaduaMuscleDays: Muscle Decline in Aging and Neuromuscular Disorders - Mechanisms and Countermeasures, Padua, IT)
• JSBBA 2017 Kyoto JP  + (2017 Annual Meeting of the Japan Society for Bioscience, Biotechnology, and Agrochemistry (JSBBA), Kyoto, Japan)
• Movement and Cognition 2018 MA US  + (2018 world conference on Movement and Cognition, Boston, Massachusetts, USA, 2018)
• Movement and Cognition 2019 Tel-Aviv IL  + (2019 World conference on Movement and Cognition, Tel-Aviv, Israel, 2019)
• 2020 PaduaMuscleDays Padua IT  + (2020 PaduaMuscleDays - 30 years of translational research, Vitual Event, 2020)
• Movement and Cognition 2020 Paris FR  + (2020 World conference on Movement and Cognition, Paris, France, 2020)
• EBEC2018 Budapest HU  + (20^th European Bioenergetics Conference 2018, Budapest, Hungary, 2018)
• SHVM 2023 Graz AT  + (20th Annual Meeting of the Society for Heart and Vascular Metabolism (SHVM), Graz, Austria, 2023)
• SFRR 2021 Virtual  + (20th Biennial Meeting of SFRR International, Virtual, 2021)
• International Botanical Congress 2024 Madrid ES  + (20th International Botanical Congress (IBC), Madrid, ES, 2024)
• EBEC2022 Aix-en-Provence FR  + (21^st European Bioenergetics Conference 2022, Aix-en-Provence, France, 2022.)
• EBEC2024 Innsbruck AT  + (22^st European Bioenergetics Conference 2024, Innsbruck, Austria, 2024)