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• McKeehan 1982 Cell Biol Int Rep
  |title=McKeehan WL (1982) Glycolysis, glutaminolysis and cell proliferation. Cell Biol Int Rep 6:635-50. ...ost abundant single amino acid in plasma, tissues and cell culture media. 'Glutaminolysis' is analogous to the glycolysis pathway that converts glucose to pyruvate.
  637 bytes (84 words) - 10:38, 23 February 2015
• Jardim-Messeder 2016 Anticancer Res
  ...Pacheco F (2016) 3-Bromopyruvic acid inhibits tricarboxylic acid cycle and glutaminolysis in HepG2 cells. Anticancer Res 36:2233-41. ...re inducing cell death. However, cancer cells are also highly dependent of glutaminolysis and tricarboxylic acid cycle (TCA) regarding survival and 3BrPA action in t
  2 KB (260 words) - 14:13, 12 June 2022
• Glutamate dehydrogenase
  ...e_dehydrogenase]. mtGDH is not part of the TCA cycle, but is involved in [[glutaminolysis]] as an [[anaplerosis |anaplerotic reaction]].
  437 bytes (54 words) - 20:16, 1 January 2021
• Fets 2022 Commun Biol
  ...s. We use these analogues to show that, under our experimental conditions, glutaminolysis-induced activation of mTORC1 can be uncoupled from PHD activity. Therefore,
  2 KB (313 words) - 18:08, 1 September 2022
• Kemp 2000 Thermochim Acta (Vol 355)
  ...conditions. There are two sources of lactate in cultured cells, oxidative glutaminolysis and reductive glycolysis. Only the latter is measured in the CR ratio as a ...pirometric ratio, Cultured cells, Anaerobic pathways, Lactate production, Glutaminolysis
  2 KB (244 words) - 14:02, 16 June 2015
• Gdynia 2016 Nat Commun
  ...enzyme 1, in advanced colon cancer. Moreover, pharmaceutical inhibition of glutaminolysis sensitizes tumour cells to HMGB1 providing a basis for a therapeutic strate
  2 KB (306 words) - 10:42, 9 November 2016
• Plecita-Hlavata 2015 J Bioenerg Biomembr
  ...input for OXPHOS from the elevated glycolysis, which together with ongoing glutaminolysis maintain a virtually unchanged respiration. Similar OXPHOS revival may expl |keywords=Cancer mitochondria, Glutaminolysis, HepG2 cells, Hypoxia-inducible factor, Non-canonical response to hypoxia,
  2 KB (327 words) - 15:40, 13 November 2017
• Malic enzyme
  == ME, aging, cancer and glutaminolysis == ...ost abundant single amino acid in plasma, tissues and cell culture media. 'Glutaminolysis' is analogous to the glycolysis pathway that converts glucose to pyruvate (
  4 KB (531 words) - 20:38, 30 April 2022
• Glutamate-anaplerotic pathway control state
  ...]] in the mitochondrial matrix. The G-pathway plays an important role in [[glutaminolysis]]. :::: Glutaminolysis: Glutamate derived from hydrolyzation of glutamine is an important aerobic
  2 KB (276 words) - 20:11, 1 January 2021
• Merlin 2021 Nat Metab
  ...y macrophages during homeostasis in mice. In addition, impaired macrophage glutaminolysis exacerbates atherosclerosis, a condition during which, efficient apoptotic
  2 KB (313 words) - 07:06, 4 September 2023
• 2-Hydroxyglutarate
  ...ld-type IDH1 and IDH2, notably under shifts toward reductive carboxylation glutaminolysis or changes in other enzymes, lead to “intermediate” 0.01–0.1 mM 2HG
  1 KB (146 words) - 16:31, 8 September 2020
• Wang H 2019 J Biol Chem
  ...cycle substrates between α-ketoglutarate and malate despite high rates of glutaminolysis, as determined by flux studies with isotopically labeled glutamine. Malate |keywords=Myc (c-Myc), Warburg effect, Fatty acid oxidation, Glutaminolysis, Pyruvate carboxylase (PC), Reverse carboxylation, Tricarboxylic acid cycle
  3 KB (397 words) - 18:52, 7 September 2023
• Zelenka 2013 Abstract MiP2013
  ...nka J, Smolkova K, Dvorak A, Vitek L, Jezek P (2013) Reverse carboxylation glutaminolysis in breast cancer cells. Mitochondr Physiol Network 18.08. ...truncated after citrate synthase; or as reductive carboxylation ("anoxic") glutaminolysis (RCG), using the only two enzymes of Krebs cycle acting in the reversed mod
  4 KB (574 words) - 18:23, 31 January 2020
• Kemp 1994 BTK-226
  ...PM, Gnaiger E (1994) A thermochemical study of the producion of lactate by glutaminolysis and glycolysis in mouse macrophage hybridoma cells. In: ''What is Controlli
  1 KB (173 words) - 19:14, 17 December 2023
• Zhao 2021 Mol Biomed
  ...erial needs via enhanced synthetic pathways, including aerobic glycolysis, glutaminolysis, fatty acid synthesis (FAS), and pentose phosphate pathway (PPP). To surviv
  2 KB (246 words) - 09:45, 12 November 2023
• Ma 2018 Cancer Lett
  ...oxylic acid cycle enzymes, and upregulation of de novo lipid synthesis and glutaminolysis. These alterations are pivotal to the development and maintenance of the ma
  2 KB (279 words) - 18:29, 12 September 2023
• Shen 2021 Cells
  ...production and survival, including mitochondrial respiration, glycolysis, glutaminolysis, and fatty acid metabolism. Because of metabolic plasticity, CSCs can switc
  2 KB (293 words) - 18:48, 8 October 2023
• Amoedo 2013 Biosci Rep
  ...nd out in the tumor phenotype and that require intact mitochondria such as glutaminolysis will be addressed. Furthermore, comments will be made as to how the peculia
  2 KB (303 words) - 15:34, 22 February 2018
• SUIT-007 O2 ce-pce D030
  :::* Protocol focused on the analysis of glutamate anaplerotic pathway/glutaminolysis in permeabilized cells (ce-pce).
  2 KB (244 words) - 09:00, 17 September 2020
• Liu 2018 Sci Adv
  ...trigger changes in distinct metabolic processes, including glycolysis and glutaminolysis, extrinsic and intrinsic mitochondrial uncoupling, and fatty acid oxidation
  2 KB (299 words) - 16:04, 18 April 2018

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