- high-resolution terminology - matching measurements at high-resolution
Oxidative phosphorylation
Description
Oxidative phosphorylation (OXPHOS) is the oxidation of reduced fuel substrates by electron transfer to oxygen, chemiosmotically coupled to the phosphorylation of ADP to ATP (PΒ») and accompanied by an intrinsically uncoupled component of respiration. The OXPHOS state of respiration provides a measure of OXPHOS capacity (P), which is frequently corrected for residual oxygen consumption (ROX).
Abbreviation: OXPHOS
Reference: OXPHOS capacity
Contributed by Gnaiger E (2010-09-10) edited 2021-01-01
OXPHOS
Figure: Energy transformation in coupled fluxes, J, and forces, F and Ξp, of oxidative phosphorylation. 2[H] indicates the reduced hydrogen equivalents of CHO fuel substrates and electron transfer to oxygen. JH+out is coupled output flux. Proton leaks dissipate energy of translocated protons from low pH in the positive to the negative compartment (from Gnaiger 2020 BEC MitoPathways).
Related terms in Bioblast
- OXPHOS; P
ROUTINE; R
ET capacity; E
LEAK; L
ROX; Rox
SUITbrowser question: OXPHOS respiration
- Β» OXPHOS capacity
- OXPHOS respiration is the focus of several SUIT protocols. The SUITbrowser can be used to find SUIT protocols for this and other research questions.
References
| Bioblast link | Reference | Year |
|---|---|---|
| Gnaiger 2009 Int J Biochem Cell Biol | Gnaiger E (2009) Capacity of oxidative phosphorylation in human skeletal muscle. New perspectives of mitochondrial physiology. Int J Biochem Cell Biol 41:1837-45. https://doi.org/10.1016/j.biocel.2009.03.013 | 2009 |
| BEC 2020.1 doi10.26124bec2020-0001.v1 | Gnaiger E et al β MitoEAGLE Task Group (2020) Mitochondrial physiology. Bioenerg Commun 2020.1. https://doi.org/10.26124/bec:2020-0001.v1 | 2020 |
MitoPedia concepts:
Respiratory state,
Recommended
MitoPedia methods:
Respirometry
MitoPedia topics:
EAGLE
