The LEAK state with ATP is obtained in mt-preparations without ATPase activity after ADP is maximally phosphorylated to ATP (State 4; Chance and Williams 1955) or after addition of high ATP in the absence of ADP (Gnaiger et al 2000). Respiration in the LEAK state with ATP, L(T), is distinguished from L(n) and L(Omy).
Reference: BEC 2020.1, Gnaiger 2020 BEC MitoPathways, Gnaiger 2000 Proc Natl Acad Sci U S A
Communicated by Gnaiger E 2010-10-18, last update 2020-04-12.
The LEAK state of respiration: towards a concept-linked terminology of respiratory states
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MitoPedia concepts: Respiratory state, Recommended
MitoPedia topics: EAGLE