Khunderyakova N
| Name | Khunderyakova Natalya, Ph.D. in Biophysics |
|---|---|
| Institution | INSTITUE OF THEORETICAL AND EXPERIMENTAL BIOPHYSICS, RUSSIA
Laboratory of Energy in Biological Systems (Prof. Maria N. Kondrasheva) |
| Address | 31-AB28,, 142290 |
| City | Pushchino, Moscow Region |
| State/Province | |
| Country | Russia |
| [email protected] | |
| Weblink | |
| O2k-Network Lab |
Labels:
Field of research: Basic, Clinical, Diagnostic
Topics: mitochondria medicine, mitochondrial physiology, blood cells β Metabolomics β Mitochondria and cancer
Publications
| Published | Reference | |
|---|---|---|
| Zakharchenko 2013 Int J Biochem Cell Biol | 2013 | Zakharchenko MV, Zakharchenko AV, Khunderyakova NV, Tutukina MN, Simonova MA, Vasilieva AA, Romanova OI, Fedotcheva NI, Litvinova EG, Maevsky EI, Zinchenko VP, Berezhnov AV, Morgunov IG, Gulayev AA, Kondrashova MN (2013) Burst of succinate dehydrogenase and Ξ±-ketoglutarate dehydrogenase activity in concert with the expression of genes coding for respiratory chain proteins underlies short-term beneficial physiological stress in mitochondria. Int J Biochem Cell Biol 45:190-200. |
| Kondrashova 2009 Int J Biochem Cell Biol | 2009 | Kondrashova M, Zakharchenko M, Khunderyakova N (2009) Preservation of the in vivo state of mitochondrial network for ex vivo physiological study of mitochondria. Int J Biochem Cell Biol 41:2036-50. |
| Khunderyakova 2008 Biochemistry (Mosc.) | 2008 | Khunderyakova NV, Zakharchenko MV, Zakharchenko AV, Kondrashova MN (2008) Hyperactivation of succinate dehydrogenase in lymphocytes of newborn rats. Biochemistry (Mosc.) 73: 337-341. |
| Vishnevsky 2003 Mitochondrion | 2003 | Vishnevsky EL, Kondrashova MN, Pushkar DY, Vishnevsky E, Demidov AA, Sirota TV, Temnov AV, Khunderyakova NV, Zakharchenko MV, Kosyakova NI (2003) Role of the impairment of oxidative metabolism in pathogenesis of lower urinary tract symptoms with benign prostatic hyperplasia and their treatment by alpha1-adrenoblocker alfuzosin. Mitochondrion 3: 67-73. |
Abstracts
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Our group has developed a novel method called the CYTO-BIO-CHEMICAL (CBCH) method for quantitative determination of physiological state of the organism. The method measures in mitochondria ex vivo the activity of enzymes such as succinate dehydrogenase (SDH) and Ξ±-ketoglutarate dehydrogenase (KDH) which are responsible for energy supply and connect mitochondria with symphatetic and parasymphatetic regulation. The novel method of SDH, KDH measurement has been improved and tested in animal model of stress, in healthy volunteers, in not critically capable patients with initial stages of metabolic syndrome accompanyied by food allergy, in patients with hypertension and start to study patients with primary revealed tumor.
